Independent validation of the adjusted GAPSS: Role of thrombotic risk assessment in the real-life setting

Lupus ◽  
2017 ◽  
Vol 26 (12) ◽  
pp. 1328-1332 ◽  
Author(s):  
N Fernandez Mosteirin ◽  
L Saez Comet ◽  
C Salvador Osuna ◽  
J M Calvo Villas ◽  
J Velilla Marco
Keyword(s):  
Risk Assessment ◽  
Real Life ◽  
Thrombotic Risk ◽  
The Real ◽  
Independent Validation ◽  
Real Life Setting

Current role of local treatments for erectile dysfunction in the real-life setting

2016 ◽  
Vol 26 (2) ◽  
pp. 123-128 ◽  
Author(s):  
Kyriakos Moisidis ◽  
Nikolaos Kalinderis ◽  
Konstantinos Hatzimouratidis
Keyword(s):  
Erectile Dysfunction ◽  
Real Life ◽  
Current Role ◽  
The Real ◽  
Real Life Setting

scholarly journals Management of Patients with Pancreatic Ductal Adenocarcinoma in the Real-Life Setting: Lessons from the French National Hospital Database

Cancers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 3515
Author(s):  
Christelle de la Fouchardière ◽  
Mustapha Adham ◽  
Anne-Marie Marion-Audibert ◽  
Antoine Duclos ◽  
Claude Darcha ◽  
...  
Keyword(s):  
Pancreatic Ductal Adenocarcinoma ◽  
Real Life ◽  
Ductal Adenocarcinoma ◽  
University Hospitals ◽  
National Hospital ◽  
Curative Intent ◽  
The Real ◽  
Oncological Treatment ◽  
Real Life Setting ◽  
Number Of Patients

Pancreatic ductal adenocarcinoma (PDAC) remains a major public health challenge, and faces disparities and delays in the diagnosis and access to care. Our purposes were to describe the medical path of PDAC patients in the real-life setting and evaluate the overall survival at 1 year. We used the national hospital discharge summaries database system to analyze the management of patients with newly diagnosed PDAC over the year 2016 in Auvergne-Rhône-Alpes region (AuRA) (France). A total of 1872 patients met inclusion criteria corresponding to an incidence of 22.6 per 100,000 person-year. Within the follow-up period, 353 (18.9%) were operated with a curative intent, 743 (39.7%) underwent chemo- and/or radiotherapy, and 776 (41.4%) did not receive any of these treatments. Less than half of patients were operated in a high-volume center, defined by more than 20 PDAC resections performed annually, mainly university hospitals. The 1-year survival rate was 47% in the overall population. This study highlights that a significant number of patients with PDAC are still operated in low-volume centers or do not receive any specific oncological treatment. A detailed analysis of the medical pathways is necessary in order to identify the medical and territorial determinants and their impact on the patient’s outcome.

scholarly journals Abiraterone in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: a systematic review of ‘real-life’ studies

2018 ◽  
Vol 10 (10) ◽  
pp. 305-315 ◽  
Author(s):  
Michele Marchioni ◽  
Petros Sountoulides ◽  
Maida Bada ◽  
Sebastiano Rapisarda ◽  
Cosimo De Nunzio ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Adverse Events ◽  
Meta Analysis ◽  
Real Life ◽  
Castration Resistant Prostate Cancer ◽  
The Real ◽  
Castration Resistant ◽  
Real Life Setting ◽  
Grade 3 ◽  
Baseline Psa

Background: To assess the efficacy and safety of treatment with abiraterone acetate (AA) in chemotherapy-naïve men with metastatic castration-resistant prostate cancer (mCRPC) in the ‘real-life’ setting. Methods: Data acquisition on the outcomes of the use of AA in chemotherapy-naive patients with mCRPC was performed by a MEDLINE comprehensive systematic literature search using combinations of the following key words: ‘prostate cancer’, ‘metastatic’, ‘castration resistant’, ‘abiraterone’, ‘real life’, and excluding controlled clinical trials (phase II and III studies). Identification and selection of the studies was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) criteria. Outcomes of interest were overall survival (OS), progression-free survival (PFS), 12-week 50% reduction in prostate-specific antigen (PSA), and grade 3 and higher adverse events. Data were narratively synthesized in light of methodological and clinical heterogeneity. Results: Within the eight identified studies that fulfilled the criteria, a total of 801 patients were included in the meta-analysis. Baseline PSA ranged between 9.5 and 212.0 ng/ml. Most of the patients had bone metastases. Duration of treatment with AA was longer in the studies with lower baseline PSA levels. The median OS ranged between 14 and 36.4 months. The PFS, assessed according to different definitions, ranged from 3.9 to 18.5 months. A 50% PSA reduction at 12 weeks was reached by a variable percentage of patients ranging from 36.0% to 62.1%. Finally, the rate of grade 3 and higher adverse events was reported in three studies and ranged from 4.4% to 15.5%. Conclusions: Despite the high grade of heterogeneity among studies, treatment with AA seems to ensure good survival outcomes in the ‘real-life’ setting. However, prospective studies based on patients’ characteristics being more similar to ‘real-life’ patients are necessary.

scholarly journals Role Playing In the Field Of Education

2018 ◽  
pp. 1-13
Author(s):  
Yuan Lo
Keyword(s):  
Real Life ◽  
Role Playing ◽  
Real Field ◽  
Real Situation ◽  
The Real ◽  
Artificial Environment ◽  
Life Education

The character and status are presented together. Others have to play the role. The real situation is to be presented in a simple way. It can be understood how to adapt yourself to the real field. The role of the actress is to be revealed. Students get real-life education in the artificial environment. Performances of speech and expression are improved.

New Perspectives Of Media-Text Under The Conditions Of Mass Media Conversion

2021 ◽  
Vol 03 (02) ◽  
pp. 28-33
Author(s):  
Avaz Khamitovich Mirzajonov ◽  
Keyword(s):  
Mass Media ◽  
Individual Recognition ◽  
Real Life ◽  
Media Convergence ◽  
The Real ◽  
Communication Processes ◽  
The Mass Media ◽  
Modern Mass

The article is devoted to the analysis of changes in the communication processes of the late XX - early XXI centuries, reflecting the powerful impact on the real life of modern mass media, the problems associated with understanding media text in the condition of Mass Media convergence, clarifying the role of the Mass Media in forming society and individual recognition and how far their influence extends on modern man.

scholarly journals Efficacy and safety of erenumab in the real-life setting of S. Antonio Abate Hospital’s Headache Center (Gallarate)

2020 ◽  
Vol 41 (S2) ◽  
pp. 465-465
Author(s):  
Elisabetta Dalla Valle ◽  
Manlio Di Falco ◽  
Andrea Mancioli ◽  
Simona Corbetta ◽  
Isidoro La Spina
Keyword(s):  
Real Life ◽  
Efficacy And Safety ◽  
The Real ◽  
Real Life Setting ◽  
Headache Center
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