The effect of age and sex on glycated hemoglobin in dogs

2021 ◽  
pp. 104063872110650
Author(s):  
Ioannis L. Oikonomidis ◽  
Theodora K. Tsouloufi ◽  
Maria Kritsepi-Konstantinou ◽  
Nectarios Soubasis

We investigated the effect of age and sex on canine glycated hemoglobin (HbA1c) using a validated capillary electrophoresis assay. Aliquots of EDTA blood samples collected for routine health checks were used. HbA1c was measured using the Capillarys 2 flex-piercing system (Sebia). We included 58 clinically and hematologically healthy, normoglycemic dogs (29 males, 29 females), allocated to 3 age groups: young (14 dogs <1-y-old), adult (31 dogs 1–7.9-y-old), and senior (13 dogs ≥8-y-old). The mean (± SD) HbA1c was not significantly different ( p = 0.428) between the age groups (young: 1.68 ± 0.54%; adult: 1.59 ± 0.41%; senior: 1.80 ± 0.57%). The HbA1c was not significantly correlated with age (rho = 0.144, p = 0.280). The median (range) HbA1c was not significantly different ( p = 0.391) between male [1.7% (0.5–2.5%)] and female [1.5% (1.0–2.7%)] dogs. Age and sex do not appear to affect canine HbA1c; however, a study of geriatric dogs would be needed to fully exclude an effect of age on HbA1c.

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1474 ◽  
Author(s):  
Aya Fujiwara ◽  
Kentaro Murakami ◽  
Keiko Asakura ◽  
Ken Uechi ◽  
Minami Sugimoto ◽  
...  

Due to a lack of a food composition database on starch and sugars, we developed a comprehensive database on starch and seven types of sugars in commonly consumed foods (n = 2222) in Japan. Dietary record data of 368 toddlers (aged 18–35 months), 376 preschool children (aged 3–6 years), 915 schoolchildren (aged 8–14 years) and 392 adults (aged 20–69 years) were used. The mean starch intake ranged from 55.6 g/day (female toddlers) to 206.0 g/day (male schoolchildren). Irrespective of age and sex, >50% of starch was provided by rice and grains. The mean total sugar intake ranged from 46.1 g/day (female toddlers) to 68.7 g/day (male schoolchildren). In all age and sex groups, the major contributors of total sugar included sucrose (mean: 18.2–34.0 g/day), glucose (7.8–13.1 g/day), lactose (5.3–13.1 g/day) and fructose (7.6–11.1 g/day). The top food sources were dairy products (toddlers) and confectionaries (other age groups) for total sugar, confectionaries for sucrose, fruits (toddlers) and vegetables (other age groups) for glucose, dairy products for lactose and fruits (toddlers and preschool children) and vegetables (schoolchildren and adults) for fructose. In conclusion, this study clarified the starch and sugar intake in Japan and provides a foundation for future research.


1998 ◽  
Vol 28 (1-2) ◽  
pp. 55-62 ◽  
Author(s):  
S. P. Whiteside ◽  
C. Hodgson

This brief study investigates the development of fundamental frequency (FO) in pre-adolescent children as a function of age and sex. The children who took part in the study were divided into three age groups: 6, 8 and 10 years. Each group consisted of three males and three females. Each subject produced nine target phrases with [] in phrase-final position, which were elicited via a picture-naming task. FO was estimated for the nine target utterances and the following FO parameters were derived: mean FO for the whole phrase; FO range for the whole phrase; standard deviation values of FO for the whole phrase and mean FO for the phrase-final vowel [α:]. Results indicated that FO parameters generally decreased with age, and by age 10 years the males had lower values than the females for all four parameters. Results also indicated that the mean standard deviation of FO across the phrase was significantly higher for the females compared to that for the males.


1987 ◽  
Author(s):  
J Vallés ◽  
M M Santos ◽  
J Aznar

Age, sex and platelet hyperactivity are factors that condition the development of coronary heart disease (CHD). Platelet function is believed to be influenced by its FA pattern, which can be modulated by the FA composition of plasma lipid fractions. Therefore, it seemed of interest to evaluate the effect of age and sex on platelet FA and ascertain whether the plasma influence on platelet FA is modified by age and sex. The study has been performed in 98 subjects, 49 couples, men (M) and women (W), living together and with the same dietary habits. The subjects were divided into three age groups : G I:16-40, GII:40-60,and G III: 60. Plasma and platelet FA of phospholipids (PL), triglycerides, and free FA fractions were evaluated by gas-chromatography. The results showed scarce differences in platelet FA in relation to sex. With respect to age, the percentages of 18:2 and 20:5 in most platelet lipid fractions both in M and in W decrease with age. More interesting are the differences in correlation found between plasma and platelet FA, particularly in the PL fraction, with age and sex. In this respect an increase in the correlation coefficient was found for 16:0,18:0 and 20:4 and a decrease for 20:5 in middle aged men and postmenopausic women (Table). The similarity between these two groups of subjects may have a physiopathological meaning, if we take into account that both are more susceptible to CHD and that an increase in 16:0, 18:0 and 20:4 as well as a decrease in 20:5 may condition a platelet hyperfuntion, circumstance that may be more easily produced by plasma influence in those subjects.The results of the present study also confirm that that in general plasma greately influences the platelet content in 18:1, 18:2 and to a lower extent the saturated FA.


1986 ◽  
Vol 32 (2) ◽  
pp. 358-360 ◽  
Author(s):  
R R Little ◽  
J D England ◽  
H M Wiedmeyer ◽  
E M McKenzie ◽  
R Mitra ◽  
...  

Abstract As the clinical utility of glycated hemoglobin (gHb) measurement increases, so does the need for standardization of values between different methods and different laboratories. Using three different methods, we examined the feasibility of interlaboratory standardization of gHb measurement. A liquid-chromatographic (HPLC) system from our research laboratory was designated the reference method. For gHb standards we used erythrocyte hemolysates prepared from blood samples from nondiabetic and diabetic subjects. Values assigned to each standard were based on the mean of multiple gHb determinations by the HPLC method. A clinical laboratory routinely prepared hemolysates and assayed gHb by commercially available ion-exchange ("mini column") and affinity chromatographic methods. For each assay a standard curve was constructed and gHb values were derived from these curves. Samples analyzed in the clinical laboratory were also analyzed in the research laboratory and the curve-derived values were compared with the HPLC-measured values, to determine the accuracy of our interlaboratory standardization procedure. Correlations were excellent (r = 0.99). The lack of significant differences between calculated and HPLC-measured values indicates that interlaboratory standardization is feasible.


1990 ◽  
Vol 104 (8) ◽  
pp. 603-605 ◽  
Author(s):  
D. Chatterjee ◽  
T. B. Ghosh ◽  
B. B. Ghosh

AbstractA radiographic planimetric study of mastoid air cell system was carried out on 100 normal human subjects of which 50 were males and 50 females–who were further subdivided into five age groups. They had no history of past ear disease or any other clinical ENT abnormality. The mean area of the mastoid air cell system was measured planimetrically on X-rays and the data analysed according to age and sex. It was 12.05±0.67 cm2 in males and 11.45±0.70 cm2 in females (which are more or less the same as that of Western people).The size of the cranial bones has no apparent role in the size variation of the mastoid air cell system. The development of the latter was very rapid up to 10 years of age in both sexes and it continued even after 20 years of age but at a much slower rate.


1968 ◽  
Vol 46 (1) ◽  
pp. 77-87 ◽  
Author(s):  
D. M. Scott ◽  
A. L. A. Middleton

An analysis of the spermatogenic condition and of the weights of testes from about 450 brown-headed cowbirds (Molothrus ater) was made to determine the annual cycle of this species at London, Ontario, and to ascertain variation in the cycle due to age. Testes of birds more than 1 year old (adult) reached maximal weights in late April and early May coincident with the beginning of egg-laying, and about 3 weeks before the testes of 1-year-old birds (yearlings) reached their maximal weight. The mean weights of testes of adults were usually greater, often significantly so, than those of yearlings. From about May 23 to June 23 there were no statistically significant differences in the weights of testes from the two age groups. Beginning in late June, the weights of testes declined rapidly in both age groups and reached a minimum in August. Minimal weights of testes persisted in captive birds until February.Large amounts of sperm were present in the testes of adults in mid-April and of yearlings in late April well in advance of maximal testicular weights. Sperm production occurred in most birds until early July but had ceased in most by late July.Testes, apparently undergoing regression, were noted significantly (p <.005) more frequently in adults than in yearlings in May and early June at the height of the breeding season. The significance of this observation and some aspects of testicular regression, previously unrecorded, are discussed. Adult birds are more sedentary than most yearlings in the breeding season and, unlike the latter, habitually associate with the same female. These behavioral differences may be related to the observed differences between the age groups in the testicular cycle.


2020 ◽  
Author(s):  
Ibrahim Sahbaz

Abstract Background: Differences in far interpupillary distance (IPD) in Turkish and Azerbaijani adults of the same ethnic background from different age groups were examined to investigate the effects of ethnicity, genetics, geography, and environmental factors on IPD. Methods: A total of 1,400 healthy individuals aged ≥18 years were enrolled. The far IPD of each individual was determined in both communities. IPD data for 700 subjects in Azerbaijan and 700 subjects in Turkey was analyzed. Males and females were divided into six age ranges: 18–24, 25–34, 35–44, 45–54, 55–64, and ≥65 years. Far IPD data in Turkey and Azerbaijan was collected using two types of autorefractometers: Topcon RM 8800 and Topcon TRK-2P.Results: The mean age of the 700 subjects in Turkey was 44.5 ± 17.6 years. The mean IPD was 62.1 ± 3.7 mm. The mean IPD in females was 61 mm, which was less than males (63 mm) (P < 0.05). The mean age of the 700 Azerbaijani subjects was 44.0 ± 15.6 years. The mean IPD of the subjects was 65.0 ± 3.1 mm. The mean IPD (64 mm) in females was significantly lower than the mean IPD (66 mm) in males (P < 0.05). Differences in IPD between age groups in both communities were statistically significant (P < 0.05). The mean IPD in all age groups in the Azerbaijani population was greater than that of the Turkish population. Compared with other ethnic groups, the mean IPD in the Azerbaijani population was remarkably high.Conclusions: When mean far IPD values in individuals aged ≥18 years in the Azerbaijani and Turkish populations were compared, statistically significant differences were observed. In Azerbaijani Turks, mean IPD values in both males and females were greater than those observed in the Turkish population in all age groups. The mean IPD values of the Azerbaijani population were greater than those of other ethnic groups when classified by both age and sex. As well as ethnicity, geographical and environmental factors influenced far IPD values.


Animals ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 660
Author(s):  
Agnieszka Ludwiczak ◽  
Joanna Składanowska-Baryza ◽  
Marek Stanisz

The goal of the study was to examine the effect of age and sex on the quality of wild boar offal and meat. A number of 32 hunt-harvested animals was assigned to groups according to age (juveniles and sub-adults) and sex. The quality of offal (liver, kidneys, heart and tongue) and m. semimembranosus was examined. The pH value of m. semimembranosus ranged from 5.45 to 5.88. The highest pH was recorded in the kidney and the liver (6.32–6.54 and 6.12–6.31). The meat in the group of juveniles was brighter (p = 0.042), yellower (p = 0.039), showed a greater drip loss (p = 0.007), cooking loss (p = 0.039), and plasticity (p = 0.028), compared to the sub-adults. The extractable fat content in the m. semimembranosus and offal (p = 0.004), and water to crude protein ratio (p = 0.033), also differed between age groups. The results of the study show different quality attributes of offal and meat of wild boars from two age groups. The obtained quality measures suggest that the culinary and technological usefulness of offal and meat from the wild boars may differ according to the age of hunted animals.


2017 ◽  
Vol 96 (10-11) ◽  
pp. E17-E22 ◽  
Author(s):  
Indranil Pal ◽  
Anindita Sinha Babu ◽  
Indranil Halder ◽  
Saumitra Kumar

Our aim was to find out the association between nasal smear eosinophil count and allergic rhinitis (AR) and to determine a cutoff value that is significant for a diagnosis of AR. We also wanted to determine whether this count is related to the predominant symptoms, duration, or type and severity of AR, or to the presence of coexisting asthma. We selected 100 patients with a clinical diagnosis of allergic rhinitis across all age groups and an equal number of age- and sex-matched controls for the study. Their nasal smear eosinophil counts were recorded in terms of the number of eosinophils per high-power field (HPF). All patients were then clinically assessed for asthma and underwent spirometry. The data were recorded and appropriate statistical analysis done. The difference in the mean eosinophil counts of patients with AR and controls was found to be statistically significant (p = 0.000). A nasal smear eosinophil count of >0.3 per HPF had a 100% specificity and a 100% positive predictive value for AR. Asthma was associated with allergic rhinitis in 40% of patients; an association was not found between nasal smear eosinophil count and the symptoms, duration, type, and severity of allergic rhinitis or coexistent asthma. We conclude that an eosinophil count of >0.3 per HPF in nasal smears is a highly specific criterion for the diagnosis of AR. However, nasal smear eosinophil counts are poor indicators of the degree, duration, or type of upper or associated lower airway inflammation due to allergy.


1959 ◽  
Vol 37 (4) ◽  
pp. 557-570 ◽  
Author(s):  
Margot R. Roach ◽  
Alan C. Burton

Autopsy specimens of iliac arteries of 63 individuals of ages between birth and 91 years have been used to measure pressure–volume curves from which elastic diagrams, i.e. tension vs. elongation, and 'elastances' were deduced. For a smaller number of specimens, the longitudinal elastance was also measured. The resistance to deformation was also derived from the amount of excess pressure outside, which was required to empty the vessel (collapse pressure). The mean curves of tension vs. stretch for the different age groups showed a remarkable increase in resistance to stretch with age for both circumferential and longitudinal elastance. The incidence of atherosclerosis, shown by the independent grading of the histologist, increased with age, but vessels not showing atherosclerosis also showed a significant increase in 'elastance' with age. The thickness of the arterial wall was increased from birth to age 20 (about 3 times) but did not change significantly thereafter. There was a significant trend for the diameter of the lumen to decrease after age 30. This was not accounted for by intimal thickening, found in some specimens of greater age. Biophysical analysis in terms of the quantity of collagen fibers present in the wall suggests that not only does the quantity of collagenous material increase with age, but more importantly, the un-stretched length of these fibers decreases with age, as the 'slack' in them is taken up, possibly by cross-linkages or adhesions.


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