Morbidity and Mortality in Cardiovascular Disorders: Impact of Reduced Heart Rate

2001 ◽  
Vol 6 (4) ◽  
pp. 313-331 ◽  
Author(s):  
Bramah N. Singh
Keyword(s):  
Heart Rate ◽  
Morbidity And Mortality ◽  
Cardiovascular Disorders

scholarly journals Short-term secondhand smoke exposure decreases heart rate variability and increases arrhythmia susceptibility in mice

2008 ◽  
Vol 295 (2) ◽  
pp. H632-H639 ◽  
Author(s):  
Chao-Yin Chen ◽  
Drin Chow ◽  
Nipavan Chiamvimonvat ◽  
Kathryn A. Glatter ◽  
Ning Li ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Secondhand Smoke ◽  
Suspended Particle ◽  
Air Pollutant ◽  
Cardiovascular Morbidity ◽  
Morbidity And Mortality ◽  
Short Term ◽  
Cardiovascular Morbidity And Mortality ◽  
Shs Exposure

Exposure to secondhand smoke (SHS), a major indoor air pollutant, is linked to increased cardiovascular morbidity and mortality, including cardiac arrhythmias. However, the mechanisms underlying the epidemiological findings are not well understood. Impaired cardiac autonomic function, indexed by reduced heart rate variability (HRV), may represent an underlying cause. The present study takes advantage of well-defined short-term SHS exposure (3 days, 6 h/day) on HRV and the susceptibility to arrhythmia in mice. With the use of electrocardiograph telemetry recordings in conscious mice, HRV parameters in the time domain were measured during the night after each day of exposure and 24 h after 3 days of exposure to either SHS or filtered air. The susceptibility to arrhythmia was determined after 3 days of exposure. Exposure to a low concentration of SHS [total suspended particle (TSP), 2.4 ± 3.2; and nicotine, 0.3 ± 0.1 mg/m3] had no significant effect on HRV parameters. In contrast, the exposure to a higher but still environmentally relevant concentration of SHS (TSP, 30 ± 1; and nicotine, 5 ± 1 mg/m3) significantly reduced HRV starting after the first day of exposure and continuing 24 h after the last day of exposure. Moreover, the exposed mice showed a significant increase in ventricular arrhythmia susceptibility and atrioventricular block. The data suggest that SHS exposure decreased HRV beyond the exposure period and was associated with an increase in arrhythmia susceptibility. The data provide insights into possible mechanisms underlying documented increases in cardiovascular morbidity and mortality in humans exposed to SHS.

scholarly journals Analisa Denyut Jantung Menggunakan Aplikasi Mobile Self Integrated BioInformatics System

2019 ◽  
Vol 6 (2) ◽  
pp. 67-74
Author(s):  
Rani Purbaningtyas
Keyword(s):  
Physical Activity ◽  
Heart Rate ◽  
Data Analysis ◽  
Professional Status ◽  
Case Based Reasoning ◽  
Cardiovascular Disorders ◽  
Rate Data ◽  
Heart Rate Data ◽  
Case Based ◽  
Heart Condition

Heart disease is still ranked first in the WHO most dangerous and deadly disease in the world. This is also influenced by the individual's reluctance to check his heart condition routinely. So we need an application that is able to help overcome this. SIBioS application is a mobile-based application that functions to analyze heart rate. SIBioS is useful to help with the initial diagnosis of the presence or absence of cardiovascular disorders in individuals. The method applied for data analysis in SIBioS applications is case-based reasoning. Each heart rate data obtained will be calculated the degree of closeness of the distance to the heart rate contained in the knowledge base owned. So that the individual's heart rate can be informed. The test results show SIBioS is able to provide information about the status of the heart condition tester in accordance with the real condition of the tester at the time of measurement. In addition to using the right data analysis method, the results of heart rate data analysis are also influenced by the smartwatch device which is used as a media for tapping heart rate data, gender, age, daily physical activity, individual professional status, and supporting factors when measuring the resting heart rate. Case-based reasoning analysis methods can be applied to heart rate analysis to determine the condition of a person's heart under normal conditions or the presence of cardiovascular disorders. The physical activity recommendations given by the system are determined based on the individual's heart condition.

scholarly journals Association of Age, Systolic Blood Pressure, and Heart Rate with Adult Morbidity and Mortality after Urgent Care Visits

2016 ◽  
Vol 17 (5) ◽  
pp. 591-599 ◽  
Author(s):  
James Hart ◽  
Michael Woodruff ◽  
Elizabeth Joy ◽  
Joseph Dalto ◽  
Gregory Snow ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Morbidity And Mortality ◽  
Urgent Care ◽  
Adult Morbidity

scholarly journals Khat (Catha Edulis) as a Risk Factor for Cardiovascular Disorders: Systematic Review and Meta-Analysis

2017 ◽  
Vol 11 (1) ◽  
pp. 146-155 ◽  
Author(s):  
Teshale Ayele Mega ◽  
Nikodimos Eshetu Dabe
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Cardiovascular System ◽  
Meta Analysis ◽  
Conclusive Evidence ◽  
Mean Difference ◽  
Cardiovascular Disorders ◽  
Khat Chewing ◽  
The Mean

Background:About 20 million people worldwide are believed to be using khat. Although some studies reported that khat chewing might result in cardiovascular disorders, conclusive evidence is limited.Method:The objective of this review was to synthesize the best available evidence for the effect of khat on the cardiovascular system. Databases searched were PubMed, Cochrane database of systematic reviews, CINAHL, poplin, LILACS, MedNar and Scopus. All papers included in the review were subjected to rigorous appraisal using the Joanna Briggs Institute (JBI) standardized critical appraisal tool. Review Manager Software (Revman 5.3) was used for meta-analysis and effect size and the 95% confidence interval (CI) was calculated.Result:Data was extracted from 10 articles. Our meta-analysis included 9,207 subjects, (2123 chewers and 7084 non-chewers, respectively) to elucidate the effect of khat on heart rate, diastolic and systolic blood pressure. The mean diastolic and systolic blood pressure of khat chewers was higher than the non-chewers with a mean difference of 5.1 mmHg, 95%CI [2.7,7.5] and 7.9 mmHg, 95%CI [2.65, 13.18], respectively. Similarly, the heart rate of the chewers remained consistently higher, making the mean difference of 6.9 beats/min, 95%CI [0.5, 13.3]. In addition, khat was found to have either a causative or worsening effect on stroke, myocardial infarction and heart failure.Conclusion:We showed that khat chewing could significantly affect the cardiovascular system through its effect on heart rate and blood pressure. Therefore, health promotion should be aimed to encourage quitting khat chewing.

scholarly journals Comprehensive pregnancy monitoring with a network of wireless, soft, and flexible sensors in high- and low-resource health settings

2021 ◽  
Vol 118 (20) ◽  
pp. e2100466118
Author(s):  
Dennis Ryu ◽  
Dong Hyun Kim ◽  
Joan T. Price ◽  
Jong Yoon Lee ◽  
Ha Uk Chung ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Body Position ◽  
Vital Signs ◽  
Blood Oxygenation ◽  
Morbidity And Mortality ◽  
Low Resource Settings ◽  
Low Resource ◽  
Vital Signs Monitoring ◽  
Wide Range

Vital signs monitoring is a fundamental component of ensuring the health and safety of women and newborns during pregnancy, labor, and childbirth. This monitoring is often the first step in early detection of pregnancy abnormalities, providing an opportunity for prompt, effective intervention to prevent maternal and neonatal morbidity and mortality. Contemporary pregnancy monitoring systems require numerous devices wired to large base units; at least five separate devices with distinct user interfaces are commonly used to detect uterine contractility, maternal blood oxygenation, temperature, heart rate, blood pressure, and fetal heart rate. Current monitoring technologies are expensive and complex with implementation challenges in low-resource settings where maternal morbidity and mortality is the greatest. We present an integrated monitoring platform leveraging advanced flexible electronics, wireless connectivity, and compatibility with a wide range of low-cost mobile devices. Three flexible, soft, and low-profile sensors offer comprehensive vital signs monitoring for both women and fetuses with time-synchronized operation, including advanced parameters such as continuous cuffless blood pressure, electrohysterography-derived uterine monitoring, and automated body position classification. Successful field trials of pregnant women between 25 and 41 wk of gestation in both high-resource settings (n = 91) and low-resource settings (n = 485) demonstrate the system’s performance, usability, and safety.

scholarly journals Fixed combination of bisoprolol and a low-dose hydrochlorothiazide in arterial hypertension

2018 ◽  
Vol 146 (5-6) ◽  
pp. 330-337
Author(s):  
Branislava Ivanovic ◽  
Milan Pavlovic ◽  
Arsen Ristic ◽  
Dragan Kovacevic
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Hypertension ◽  
Thiazide Diuretic ◽  
Beta Blockers ◽  
Cardiovascular Morbidity ◽  
Morbidity And Mortality ◽  
Thiazide Diuretics ◽  
Cardiovascular Morbidity And Mortality ◽  
Dose Dependent

Beta-blockers showed better results in lowering elevated blood pressure in the younger age group of patients with higher renin plasma levels. Actual recommendations from the European Society of Cardiology for treatment of arterial hypertension from 2013 insist that heart rate should always be measured along with blood pressure. These recommendations point out the significance of resting heart rate as an independent predictor of cardiovascular morbidity and mortality in patients with arterial hypertension. Beta-blockers have a compelling indication for treatment of arterial hypertension in patients with coexistence of coronary artery disease, especially post myocardial infarction, as well as in patients with systolic heart failure. Bisoprolol, a highly selective beta-blocker with a long half-life and a prolonged antihypertensive effect, has shown consistent blood pressure control over a period of 24 hours. It has been demonstrated in placebo-controlled studies that administration of thiazide diuretics, in addition to lowering blood pressure levels, had also been associated with a reduction of cardiovascular morbidity and mortality rates. It is evident that effectiveness of thiazide diuretics is dose-dependent; however, undesirable effects of drugs are also dose-dependent. Depending on the dose, they aggravate glucose intolerance, increase lipid levels, cause hypokalemia, hyponatremia, and hypomagnesemia, and increase levels of uric acid. Administration of very low doses of a thiazide diuretic is acceptable in combination with other antihypertensive drugs, because it potentiates the action of other drugs without causing undesirable metabolic effects. The effectiveness and safety of the combination of bisoprolol (in various doses) and a thiazide diuretic in a small dose has been proven in clinical trials.

Sign in / Sign up

Export Citation Format

Share Document