Comparison of phaco time parameters in eyes with and without glaucoma filtration surgery due to pseudoexfoliation glaucoma

2021 ◽  
pp. 112067212110177
Author(s):  
Ayse Gul Kocak Altintas ◽  
Cagri Ilhan
Keyword(s):  
Clinical Characteristics ◽  
Pseudoexfoliation Glaucoma ◽  
Filtration Surgery ◽  
Glaucoma Filtration Surgery ◽  
Mean Values ◽  
Time Parameters ◽  
The Mean ◽  
Group 2 ◽  
Surgical Manipulations ◽  
Phaco Time

Purpose: To compare the phaco time parameters including ultrasound time (UST), effective phaco time (EPT), and average phaco power (APP) in eyes with pseudoexfoliation glaucoma (PEG) and had or had not glaucoma filtration surgery. Methods: In this retrospective comparative study, Group 1 was constructed with 84 PEG patients who had not operated previously, and Group 2 was constructed with 49 PEG patients who had glaucoma filtration surgery. The mean values of UST, EPT, and APP were compared. The preoperative clinical characteristics and surgical manipulations were also compared. Results: The mean ages and male-to-female ratios of the groups were similar ( p > 0.05, for both). There was no difference in the preoperative clinical characteristics, including biometric values between the groups ( p > 0.05, for all). Some surgical manipulations, including pupillary stretching ( p = 0.004), pupillary membrane peeling ( p = 0.021), iris hook using ( p = 0.041), and capsular tension ring implantation ( p = 0.041), were significantly performed more commonly in Group 2. Although the mean UST and EPT values were similar ( p > 0.05, for both), the mean APP value was significantly lower in Group 2 ( p = 0.011). Conclusion: The lower APP parameter was observed in PEG patients having had glaucoma filtration surgery. Needing more surgical manipulation to overcome poor pupillary dilation and weak zonular instability can be a reason for this result.

scholarly journals The Effect of Glaucoma Filtration Surgery on Structural and Functional Eye Parameters in a Short-Term Study

2017 ◽  
Vol 71 (1-2) ◽  
pp. 27-32
Author(s):  
Kristīne Baumane ◽  
Renāte Ranka ◽  
Guna Laganovska
Keyword(s):  
Optic Nerve ◽  
Visual Fields ◽  
Glaucoma Surgery ◽  
Treatment Method ◽  
Positive Influence ◽  
Retinal Nerve Fibre Layer ◽  
Filtration Surgery ◽  
Glaucoma Filtration Surgery ◽  
Mean Values ◽  
The Mean

Abstract Glaucoma filtration surgery (trabeculectomy) is an effective glaucoma treatment method that provides significant intraocular pressure (IOP) reduction. Indications for this method are in cases where other forms of therapy, like medicines or lasers, have failed, other forms of therapy are not suitable (compliance or side-effects are a problem), in cases where a target pressure is required to prevent clinically significant disease progression that cannot be reached with topical medications and/or laser and in cases that have such advanced glaucoma and high IOP at presentation that other forms of treatment are unlikely to be successful. The aim of this study was to evaluate the effect of glaucoma surgery on the structural and functional eye parameters at different stages of glaucoma. A total of 96 eyes of 96 patients (only one eye from each patient) with different stages of glaucoma (stages 2 to 4) who were undergoing trabeculectomy were recruited. Quadrant retinal nerve fibre layer RNFL) thickness (33 patients), cup/disc vertical and horizontal ratio (36 patients) and MD of visual fields (27 patients) were analysed up to one week before and 1 month after the successful surgery. The results show that the MD value was slightly improved in 50%, 85.7%, and 71.4% of patients with glaucoma stages 2, 3, and 4, respectively. The mean RNFL of all four optic nerve head quadrants increased slightly after the surgery for patients with glaucoma stage 2; in contrast, a decrease in the mean RNFL values for all four quadrants was observed for patients with glaucoma stage 4. Statistically significant changes in the mean values for the optic nerve horizontal c/d ratio after glaucoma surgery were observed (p = 0.033) in contrast to the vertical c/d values (p = 0.77). In total, improvement of the horizontal and vertical c/d ratio was detected in 61.1% and 55.6% of the glaucoma patients, respectively. Although the observed changes were statistically insignificant, the positive influence of glaucoma surgery on the structural and functional eye parameters was more pronounced in moderate stages than in advanced or severe stages of glaucoma.

Application of femtolaser-assisted phacoemulsification in combined pathology of cataract and glaucoma

2021 ◽  
pp. 18-21
Author(s):  
A.P. Voznyuk ◽  
◽  
S.I. Anisimov ◽  
S.Y. Anisimova ◽  
L.L. Arutyunyan ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Biomechanical Properties ◽  
Mean Values ◽  
Long Term Follow Up ◽  
The Mean ◽  
Group 2 ◽  
Observation Period ◽  
Group 1

Purpose. To evaluate the efficacy and safety of femtolaser-assisted phacoemulsification in glaucomatous eyes in the long-term follow-up. Materials and methods. A retrospective analysis of the results of the surgical treatment of patients with combined cataract and glaucoma pathology was analyzed. The patients were divided into groups depending on the method of surgical intervention: 1) phacoemulsification with femtolaser support (26 eyes, 23 patients); 2) phacoemulsification (36 eyes, 30 patients); Results. Before surgery, there were no statistically significant differences in IOP and corneal hysteresis (СН) between groups 1 and 2. The mean values of IOP cc, IOP g and СН of group 1 before surgery were 22.7±6.1 mm Hg, 20.9±6.9 mm Hg, 8.5±1.6 mm Hg; 2 group – 22.9±8.7 mm Hg, 21.6±8.9 mm Hg, 8.9±1.6 mm Hg respectively. Average values of IOP cc, IOP g and CН 5 years after the surgical treatment in group 1 were 15.3±1.2 mm Hg, 14.4±3.4 mm Hg, 9.6±4.2 mm Hg; in group 2 – 18.0±4.2 mm Hg, 16.1±4.2 mm Hg, 8.8±2.2 mm Hg respectively. In both groups, stabilization of IOP and CH indices was noted, which remained throughout the entire observation period, which shows the normalization of the biomechanical properties of the corneoscleral membrane of the eye in the long-term postoperative period. Conclusion. Femtolaser accompaniment of phacoemulsification is an effective and safe method of cataract surgery for combined pathology. Key words: femtolaser, cataract, glaucoma, phacoemulsification.

Mechanism of the glucocorticoid-induced increase in glomerular filtration rate

1978 ◽  
Vol 234 (2) ◽  
pp. F166-F170 ◽  
Author(s):  
C. Baylis ◽  
B. M. Brenner
Keyword(s):  
Control Group ◽  
Hydraulic Pressure ◽  
Mean Values ◽  
Pressure Equilibrium ◽  
The Mean ◽  
Glomerular Ultrafiltration ◽  
Group Averaging ◽  
Group 2 ◽  
Normal Controls ◽  
Group 1

In order to investigate the mechanism(s) by which glucocorticoids increase GFR the determinants of glomerular ultrafiltration were measured in two groups of seven Munich-Wistar rats. Group 1 rats were normal controls and group 2 rats were pretreated with methylprednisolone (MP), 15 mg/kg per day for 4 days prior to study. In rats given MP mean values for SNGFR were about 25% higher than in the control group, averaging 33.6 +/- 1.6 (SE) vs. 27.0 +/- 1.0 nl/min. Mean values for initial glomerular plasma flow rate (QA) were also about 25% higher in MP-treated rats, averaging 83.4 +/- 3.9 vs. 65.9 +/- 1.9 nl/min in controls. Mean values of the transglomerular hydraulic pressure difference (deltaP) as well as afferent (IIA) and efferent (IIE) oncotic pressures were essentially similar between control and MP-treated rats. Filtration pressure equilibrium, i.e., equality between IIE and deltaP, obtained in both groups and the mean minimum estimates of the ultrafiltration coefficient (Kf) were also similar between control and MP-treated rats. Thus, the rise in SNGFR following MP is entirely due to the increase in AQ, rather than to changes in the other determinants of ultrafiltration.

scholarly journals Techniques for preparing of guide planes: in vitro comparative study

2014 ◽  
Vol 17 (2) ◽  
pp. 20 ◽  
Author(s):  
Eduardo Shigueyuki Uemura ◽  
João Maurício Silva ◽  
Alexandre Luiz Souto Borges ◽  
Eron Toshio Colauto Yamamoto
Keyword(s):  
Removable Partial Denture ◽  
Mean Values ◽  
Group 4 ◽  
Intraoral Device ◽  
Significant Difference ◽  
Group 3 ◽  
The Mean ◽  
Group 2 ◽  
Preparation Techniques

<p>The correct parallelism of guiding planes when constructing a Removable Partial Denture not only defines the axis of insertion and removal of the prosthesis, but also limits the possible axes of movement during functioning. Therefore, the purpose of the study was to compare some techniques and the use of an intra-oral device for those preparations. Dummies were performed in a direct manner, simulating the absence of teeth 15, 45, 12 and 42. The four preparation techniques chosen were: Group 1 – freehand preparation; group 2 - guide pins; Group 3 - crown guides and Group 4 - parallel intraoral device – ParalAB. No statistical difference was shown between the mean values of angles found for the freehand (82.85°) and guide pin (83.60°) groups. Also, no statistical significant difference was observed between the mean values of angles found for the resin cap (of 88.83) and intraoral device (88.58 º) groups; however they were superior to the findings for the freehand and guide pin groups. The studied methods are effective for what they were proposed; however, one should select the method according to the experience and skills, to promote the best results.</p>

scholarly journals Influence of Anterior Guidance on the Inclination of Horizontal Condylar Guidance in Dentulous Subjects - A Clinical Study

2021 ◽  
Vol 10 (28) ◽  
pp. 2072-2077
Author(s):  
Naresh Shetty ◽  
Sanath Shetty ◽  
Hasan Sarfaraz ◽  
Syed Ghouse Ahmed ◽  
Fahad Mohammad
Keyword(s):  
Pearson Correlation ◽  
Mean Values ◽  
Incisal Edge ◽  
Anterior Guidance ◽  
Correlation Tests ◽  
The Mean ◽  
Group 2 ◽  
The Right ◽  
Interocclusal Records ◽  
One Way Anova

BACKGROUND One of the most widely used methods to record horizontal condylar guidance is the use of protrusive interocclusal records. Therefore, this study was done to evaluate the reliability of protrusive interocclusal record with and without the influence of anterior determinant on horizontal condylar guidance among dentulous patients. METHODS Diagnostic impressions of 21 participants were made and casts were poured. Facebow record were obtained and transferred to semi-adjustable articulator. Protrusive interocclusal records were made using Alu-wax. In group 1, protrusive interocclusal records were obtained at incisal edge to edge position (conventional method). In group 2, 3 and 4 protrusive interocclusal records were obtained at a distance of 4 mm, 6 mm and at incisal edge to edge position respectively using a customized flat anterior jig. Programming of the Hanau articulator were done for all the 4 groups. One-way ANOVA test and Pearson’s correlation tests were done to compare and correlate horizontal condylar guidance. RESULTS The mean values obtained for flat anterior jig at incisal edge to edge position, at 4 mm and 6 mm provided good Pearson correlation values for the right (R = 0.773, R = 0.779, R = 0.632) as well as the left side (R = 0.631, R = 0.601, R = 0.545) respectively, on comparison with the conventional incisal edge to edge values. This indicated a positive correlation which was statistically significant. CONCLUSIONS The horizontal condylar guidance is influenced by anterior determinant. Therefore, the reliability of protrusive records is dependent on eliminating the influence of anterior determinant. KEY WORDS Horizontal Condylar Guidance, Anterior Determinant, Protrusive Interocclusal Records

scholarly journals Validity of Autotaxin as a Novel Diagnostic Marker for Liver Fibrosis in Egyptian Chronic HCV Patients

2013 ◽  
Vol 1 (1) ◽  
pp. 21-26 ◽  
Author(s):  
Wafaa M. Ezzat ◽  
Halla M. Ragab ◽  
Nabila Abd El Maksoud ◽  
Nour A. Abdulla ◽  
Yasser A. Elhosary
Keyword(s):  
Liver Fibrosis ◽  
Diagnostic Marker ◽  
Fibrosis Score ◽  
Laboratory Assessment ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean ◽  
Group 2 ◽  
Chronic Hcv ◽  
Group 1

We aimed to detect the validity of serum ATX as a diagnostic marker for liver fibrosis. Forty-eight males and 16 females were enrolled in the current study. Their ages ranged from 29-57 years with mean of 45.09, all were chronically HCV infected. Laboratory assessment was done for all subjects in form of complete blood picture; liver function test; lipid profile and serum detection of ATX. Patients were grouped according to the stage of fibrosis into group 1: fibrosis score 0, 1, 2, 3; group 2: fibrosis score: 4, 5, 6.The mean values of ATX in all studied patients with chronic HCV infection was 63.02 ± 36.29 while that of healthy controls was 65.31 ± 12.24 without any significant difference. Surprisingly, mean values of ATX were higher among patients with group 1 but it did not reach the significant level. In each group of them, the differences between mean values of ATX among different grades of liver fibrosis were insignificant. It was also noticed that the mean values of ATX were higher among men than in women .It was concluded that Autotoxin might not be used as a useful diagnostic marker for liver fibrosis in Egyptian chronic HCV patients.

Correlation between GSV diameter and varicose clinics

Phlebologie ◽  
2016 ◽  
Vol 45 (01) ◽  
pp. 29-35 ◽  
Author(s):  
F. Amsler ◽  
E. Kalodiki ◽  
E. Mendoza
Keyword(s):  
Varicose Veins ◽  
Clinical Severity ◽  
Venous Disease ◽  
Published Data ◽  
Mean Values ◽  
Venous Clinical Severity Score ◽  
The Mean ◽  
Group 2 ◽  
Disease Stratification ◽  
Group 1

Summary Background Great saphenous vein (GSV) incompetence is involved in the majority of cases of varicose disease. Stratification of venous disease severity is still difficult. This study aims to correlate GSV diameters with C of CEAP and the venous clinical severity score (VCSS). Methods Legs without GSV reflux (Control legs, Group 1) and legs with untreated isolated GSV reflux and varicose veins limited to the GSV territory (Group 2) were studied clinically and with duplex ultrasound in a prospective study. The GSV diameters were measured both next to the saphenofemoral junction (SFJ) and at proximal thigh (PT) and correlated to the C of CEAP and VCSS. Results The control legs-group 1 were: n=33, 6 male, mean age 53, mean BMI 26.The legs with reflux-group 2 were: n=78, 16 male, mean age 54, mean BMI 27.The mean diameters for the SFJ ( ± SD) for groups 1 and 2 were 6.4 ± 1.8 and 9.9 ± 3.4. For PT they were 3.6 ± 0.9 and 5.9 ± 1.8 respectively. In legs with reflux the SFJ diameter correlates strongly with the PT diameter (r=0.69) and moderately with the C of CEAP and VCSS; 0.42 and 0.45 respectively. The PT diameter correlates slightly better with the C of CEAP and VCSS than the SFJ diameter (0.55 and 0.57). The mean values of VCSS for groups 1 and 2 were 0.70. and 4.69. The C of CEAP and VCSS show a strong correlation among them with r=0.79 in group 2 and 0.80 in the whole sample. Conclusion The GSV diameters next to the SFJ and particularly at the PT in patients having reflux correlate strongly with both the C of CEAP and VCSS. Recording the GSV diameters at the SFJ and PT in a standardized way may improve comparison of published data and contribute to choice of treatment in the future.

scholarly journals Evaluation of Choroidal Thickness in Patients with Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Ayhan Dursun ◽  
Ayse Vural Ozec ◽  
Oznur Dogan ◽  
Feyza Gulac Dursun ◽  
Mustafa Ilker Toker ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Choroidal Thickness ◽  
Healthy Controls ◽  
Pseudoexfoliation Glaucoma ◽  
Mean Values ◽  
Glaucomatous Damage ◽  
Peripapillary Choroidal Thickness ◽  
The Mean ◽  
Glaucoma Group

Purpose. To compare the macular and peripapillary choroidal thickness in eyes with pseudoexfoliation (PEX) syndrome and PEX glaucoma with the normal eyes of healthy controls.Materials and Methods. In this prospective study, 30 eyes of 30 patients with PEX syndrome, 28 eyes of 28 patients with PEX glaucoma, and 30 eyes of 30 age-matched healthy subjects were enrolled. Choroidal thicknesses in the macular and peripapillary areas were measured by using spectral domain optical coherence tomography.Results. Gender, age, and axial length did not significantly differ between the groups (all,p>0.05). The mean values of choroidal thickness in the macular and peripapillary areas (except the superior quadrant) in the patients with PEX syndrome and PEX glaucoma were lower compared with controls (allp<0.05). The mean values of the macular and peripapillary choroidal thickness in the PEX glaucoma group were lower compared with PEX syndrome group; however this difference was not significant.Conclusions. The findings of this study revealed that macular and peripapillary choroidal thicknesses were decreased in PEX syndrome and PEX glaucoma cases. The role of choroid in the development of glaucomatous damage in patients with PEX syndrome remains unclear.

scholarly journals Longitudinal Evaluation of Bond Strength to Enamel of Dental Adhesive Systems Associated with Nd:YAG Laser

2015 ◽  
Vol 40 (3) ◽  
pp. E122-E131 ◽  
Author(s):  
DC Barcellos ◽  
GR Batista ◽  
CR Pucci ◽  
ES Persici ◽  
AB Borges ◽  
...  
Keyword(s):  
Bond Strength ◽  
Laser Irradiation ◽  
Nd:Yag Laser ◽  
Storage Time ◽  
Interaction Technique ◽  
Mean Values ◽  
Group 4 ◽  
Electron Microscope Analysis ◽  
The Mean ◽  
Group 2

SUMMARY Objectives This study evaluated the durability of bond strength to enamel using total-etch (Single Bond/SB) and self-etch (Clearfil SE Bond/CSEB) adhesives associated with neodymium:yttrium-aluminu- garnet (Nd:YAG) laser irradiation through the uncured adhesives. Methods Bovine incisors were worn to expose an area of enamel and were divided into four groups: group 1 (control) SB + polymerization; group 2 (control) CSEB + polymerization; group 3 (laser) − SB + Nd:YAG laser (174.16 J/cm2) + polymerization; and group 4 (laser) CSEB + Nd:YAG (174.16 J/cm2) + polymerization. Blocks of composite were fabricated and stored for 24 hours or 12 months, sectioned into beams, and submitted to microtensile tests. Results were analyzed by three-way analysis of variance (ANOVA) (adhesive, technique, and storage time) and Tukey tests. Results ANOVA revealed significant differences for adhesive × technique and technique × storage time (p&lt;0.05). The mean values (MPa) for interaction adhesive × technique (standard deviation) were as follows: SB/control = 35.78 (6.04)a; SB/laser = 26.40 (7.25)b, CSEB/control = 26.32 (5.71)b, CSEB/laser = 23.90 (7.49)b. For interaction technique × storage time the mean values were as follows: control/24 hours = 32.58 (6.49)a; control/12 months = 29.52 (8.38)a; laser/24 hours = 29.37 (5.71)a; laser/12 months = 20.92 (6.5)b. Groups with the same letters showed no statistically significant differences. Conclusion Scanning electron microscope analysis showed evident areas of micromorphological alterations in lased samples after 12 months of water storage. Nd:YAG laser irradiation of enamel through unpolymerized total-etch adhesive significantly reduced bond strength compared with the control. Bond strength decreased when enamel samples irradiated with Nd:YAG laser through unpolymerized adhesives were stored in water for 12 months.

scholarly journals MARKERS LEVEL OF ENDOTHELIAL DYSFUNCTION (ENDOTELIN-1 AND NITROGEN OXIDE) IN BLOOD SYROVISTS AND ALBUMINURIA IN CHILDREN WITH ERYTHROCYTURIA

2017 ◽  
pp. 49-54
Author(s):  
V. Minakova
Keyword(s):  
Endothelial Dysfunction ◽  
Kidney Diseases ◽  
Control Group ◽  
Mean Values ◽  
Endothelium Dysfunction ◽  
Hereditary Nephritis ◽  
Group 3 ◽  
The Mean ◽  
Group 2 ◽  
Group 1

The aim of our study was to investigate the levels of endothelin-1 and aside nitrogen in the serum of children with kidney diseases that clinically present with hematuria syndrome. Materials and methods: a total of 158 children aged 1 to 18 years with kidney disease, having a course with hematuria. Patients were divided into 3 groups: group 1 – glomerulonephritis; group 2 – hereditary nephritis; group 3 – dismetabolic nephropathy. It was studied the level of endothelin, nitric oxide in serum, the level of hematuria, AU in urine, blood biochemistry, glomerular filtration. Results: the highest level of ET-1 was detected in patients with glomerulonephritis - 0,82±0.055 fmol/ml, with the variation range from 0.10 to 3.2 fmol/ml, which twice exceeded the mean values in the control group, whereas the growth rate of hereditary nephritis and DN was more moderate (0,64±0,063 and 0,54±0,072 fmol/ml, respectively). The NO level increased significantly in patients with glomerulonephritis to 120,2±12,3 μmol/l. Conclusions. Determining the level of ET-1 and NO in the serum of children with kidney diseases, having a course with hematuria, gives the opportunity to get an idea about the presence of endothelium dysfunction. Indicators of endothelial dysfunction can be used as markers of severity and progression of the disease.

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