Lipodystrophia Centrifugalis Abdominalis Infantilis

2016 ◽  
Vol 20 (4) ◽  
pp. 349-351
Author(s):  
Daniel Paluzzi ◽  
Tess Peters ◽  
Richard M. Haber
Keyword(s):  
Plasma Cells ◽  
Age Of Onset ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Fat Necrosis ◽  
Lower Abdomen ◽  
Ipsilateral Side ◽  
First Case ◽  
Dermatological Condition ◽  
Inguinal Lymphadenopathy

Background: Lipodystrophia centrifugalis abdominalis infantilis (LCAI) is an uncommon dermatological condition characterized by a centrifugally expanding area of lipoatrophy involving the lower abdominal area and is frequently associated with inguinal lymphadenopathy. The average age of onset is 4 years and female individuals from Japan, China, and Korea are affected more often. Objectives: To report the first case of LCAI in a Vietnamese patient. Methods: A complete clinical assessment was done and a biopsy from the affected area was performed. Results: There was an atrophic, slightly hyperpigmented patch at the lower abdomen with prominent underlying vasculature. Inguinal lymphadenopathy was noted on the ipsilateral side. A biopsy showed a lobular panniculitis with fat necrosis and lymphohistiocytic infiltrate with scattered plasma cells and multinucleated giant cells. Conclusion: To our knowledge, this is the first reported case of LCAI in a Vietnamese patient.

Calcium oxalate granuloma of the nose of a chronically dialysed nephritic patient

2001 ◽  
Vol 115 (6) ◽  
pp. 514-516 ◽  
Author(s):  
Andrej Böör ◽  
Ivan Jurkovič ◽  
Imrich Friedmann ◽  
Marian Benický ◽  
Pavol Kočan
Keyword(s):  
Calcium Oxalate ◽  
Nasal Cavity ◽  
Interstitial Nephritis ◽  
Granulation Tissue ◽  
Plasma Cells ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Polypoid Mass ◽  
Left Nasal Cavity ◽  
Crystalline Deposits

The patient was a 54-year-old woman who had been suffering from chronic tubulo-interstitial nephritis for about seven years, requiring haemodialysis. More recently, she developed a polypoid mass in the left nasal cavity causing discomfort on breathing and slight epistaxis. The tumour was of gritty consistency and measured 28 × 8 × 5 mm. Microscopy showed a lobulated almost cystic structure composed of granulation tissue with comparatively few plasma cells and many multinucleated giant cells lining the spaces filled with crystalline deposits of calcium oxalate.

Intralymphatic Histiocytosis of the Appendix and Fallopian Tube Associated With Primary Peritoneal High-Grade, Poorly Differentiated Adenocarcinoma of Müllerian Origin

2017 ◽  
Vol 25 (4) ◽  
pp. 357-364
Author(s):  
Tien Anh N. Tran ◽  
Quang Tran ◽  
J. Andrew Carlson
Keyword(s):  
Fallopian Tube ◽  
Giant Cells ◽  
Pathological Process ◽  
High Grade ◽  
Multinucleated Giant Cells ◽  
Current Case ◽  
Poorly Differentiated Adenocarcinoma ◽  
First Case ◽  
Poorly Differentiated ◽  
Intralymphatic Histiocytosis

Intralymphatic histiocytosis (ILH) is a peculiar pathological process characterized by the collections of benign histiocytes in dilated lymph vessels. Although the majority of ILH patients present clinically with various forms of cutaneous manifestation, rare extracutaneous incidences have been reported in the literature. To date, ILH has not been described in an internal visceral organ. We report the case of a 68-year-old woman who underwent an appendectomy during a surgical procedure for a primary peritoneal high-grade, poorly differentiated adenocarcinoma of Müllerian origin. Although no malignancy was identified in the appendix, the appendiceal mucosa and submucosa were expanded by dilated vascular channels harboring aggregates of uniform epithelioid cells. Similar histological changes were also identified in the right fallopian tube. Immunohistochemical studies revealed the lymphatic nature of the vessels and the histiocytic origin of the intravascular cells. Of note was the presence of scattered multinucleated giant cells in the histiocytic population, a histological feature not described hitherto in ILH. To the best of the authors’ knowledge, this is the first case of ILH harboring multinucleated giant cells, involving internal visceral organs, and associated with a malignant tumor of the gynecological system. As such, the current case report expands the clinical and histological spectrum of ILH.

scholarly journals Xanthogranulomatous salpingo-oophoritis: a case report and review of literature

2020 ◽  
Vol 9 (10) ◽  
pp. 4316
Author(s):  
Keval A. Patel ◽  
Kinalee P. Chothani ◽  
Bimal Patel ◽  
Dhaneshwar N. Lanjewar
Keyword(s):  
Case Report ◽  
Rare Disease ◽  
Plasma Cells ◽  
Giant Cells ◽  
Ovarian Tumour ◽  
Multinucleated Giant Cells ◽  
Review Of Literature ◽  
Xanthogranulomatous Inflammation ◽  
Extensive Surgery

Xanthogranulomatous inflammation of ovary is a rare disease that is characterized by presence of large number of lipid laden macrophages with an admixture of neutrophils, lymphocytes, plasma cells and multinucleated giant cells. It is misdiagnosed as ovarian tumour that leads to extensive surgery including hysterectomy. In this report we describe a case of Xanthogranulomatous salpingo-oophoritis along with review of literature.

Primary Paranasal Aspergillus Granuloma: Case Report and Review of the Literature

2002 ◽  
Vol 16 (3) ◽  
pp. 165-168 ◽  
Author(s):  
John Currens ◽  
Patricia S. Hutcheson ◽  
Raymond G. Slavin ◽  
Martin J. Citardi
Keyword(s):  
United States ◽  
Chronic Infection ◽  
Plasma Cells ◽  
Giant Cells ◽  
The United States ◽  
Fungal Sinusitis ◽  
Review Of The Literature ◽  
Invasive Fungal Sinusitis ◽  
First Case ◽  
Chronic Invasive

Background Primary paranasal aspergillus granuloma (PPAG) is a slowly progressive chronic infection of the sinus extending beyond the confines of the sinus. It has been reported only in patients from the Sudan and India. Microscopically, it differs from chronic invasive fungal sinusitis in that there are pseudotubercles containing giant cells, histiocytes, lymphocytes, plasma cells, newly formed capillaries, eosinophils, and Aspergillus fungal elements. Conclusion We describe the first case of PPAG in the United States in an immunocompetent nonatopic woman who had never left Missouri.

scholarly journals Granulomatous myelitis associated with hemorrhagic syndrome due to consumption of Vicia villosa by cattle

2010 ◽  
Vol 40 (8) ◽  
pp. 1848-1851 ◽  
Author(s):  
Luciana Sonne ◽  
Djeison Lutier Raymundo ◽  
Nadia Aline Bobbi Antoniassi ◽  
Paulo Mota Bandarra ◽  
Paula Rodrigues de Almeida ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Unusual Case ◽  
Plasma Cells ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Vicia Villosa ◽  
Holstein Cow ◽  
Microscopic Findings

An unusual case of spontaneous Vicia villosa poisoning affected a 6-year-old Holstein cow. Although the most striking findings included a generalized hemorrhagic condition associated with granulomatous myelitis, histological lesions typically seen with the vetch-associated systemic granulomatous syndrome were also present. Prominent gross findings were bloody nasal and oral discharges, disseminated hemorrhages, and bloody feces. Generalized hemorrhages associated with infiltration of numerous organs by lymphocytes, plasma cells, macrophages, multinucleated giants cells, and eosinophils were the main microscopic findings. Anti-CD68 immunostaining confirmed the presence of moderate histiocytic infiltrate and multinucleated giant cells in the bone marrow. These changes in the bone marrow probably caused the generalized hemorrhagic changes described here.

scholarly journals Meningoencephalitis Tuberculosa in a Holstein Cow

2005 ◽  
Vol 42 (6) ◽  
pp. 856-858 ◽  
Author(s):  
E. Oruç
Keyword(s):  
Bovine Spongiform Encephalopathy ◽  
Plasma Cells ◽  
Clinical Signs ◽  
Giant Cells ◽  
Spongiform Encephalopathy ◽  
Multinucleated Giant Cells ◽  
Holstein Cow ◽  
Acid Fast Bacilli ◽  
The Brain

The gross and histopathologic lesions of meningoencephalitis tuberculosa in a 4-year-old Holstein cow showing clinical signs compatible with bovine spongiform encephalopathy are described in this report. Grossly, numerous gray to yellow, firm and caseous nodules were seen on the ventral surfaces of the brain and in the lateral and fourth ventricles. Histopathologically, foci of caseation and dystrophic mineralization were surrounded by multinucleated giant cells, epitheloid macrophages, plasma cells, lymphocytes and fibrous proliferation. Ziehl-Neelsen stains of the lesions revealed masses of slender acid-fast bacilli in the necrotic centers of lesions and within surrounding giant cells.

scholarly journals  Avian tuberculosis in a captured Ruppell's griffon vulture (Gyps ruppellii): a case report

2010 ◽  
Vol 55 (No. 7) ◽  
pp. 348-352 ◽  
Author(s):  
M. Skoric ◽  
P. Fictum ◽  
L. Frgelecova ◽  
P. Kriz ◽  
I. Slana ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Granulomatous Inflammation ◽  
Giant Cells ◽  
Body Cavity ◽  
The Body ◽  
Multinucleated Giant Cells ◽  
Quantitative Real Time Pcr ◽  
Griffon Vulture ◽  
Avium Infection ◽  
Variable Layer

Avian tuberculosis was diagnosed in a captured female Ruppell's griffon vulture (Gyps ruppellii) with granulomatous splenitis and hepatitis. At necropsy, whitish to yellow nodules of various sizes were found in the spleen and liver, and fibrinous coelomitis was present in the body cavity. Histopathologically, the granulomas appeared to be typical of avian tuberculosis. In some granulomas, necrotic centres surrounded by a variable layer of palisading epithelioid macrophages and multinucleated giant cells with variable admixture of lymphocytes and plasma cells were present. Signs of mineralization in granulomas were not observed. Using Ziehl-Neelsen staining the presence of acid-fast bacilli was demonstrated in organs affected by granulomatous inflammation. A diagnosis of Mycobacterium avium subsp. avium infection was confirmed by culture and quantitative Real-Time PCR examination for the presence of specific insertion sequences for avian tuberculosis (IS901 and IS1245) in the liver and spleen.  

scholarly journals Cellular Composition of Calcified Bioprosthetic Heart Valves

2015 ◽  
Vol 70 (6) ◽  
pp. 662-668 ◽  
Author(s):  
Rinat Avkhadievich Mukhamadiyarov ◽  
Natal'ya Vital'evna Rutkovskaya ◽  
Ol'ga Dmitrievna Sidorova ◽  
Leonid Semenovich Barbarash
Keyword(s):  
Smooth Muscle ◽  
Heart Valves ◽  
Plasma Cells ◽  
Giant Cells ◽  
Cellular Infiltration ◽  
Cellular Composition ◽  
Multinucleated Giant Cells ◽  
Bioprosthetic Heart Valves ◽  
Calcium Deposits ◽  
Multiple Cells

With the aim to assess the mechanisms of the structural dysfunctions associated with xenograft tissue calcification, we investigated the cellular composition of the explanted xenoaortic epoxy-treated bioprosthetic heart valves. In the leaflets, we revealed multiple cells with retained internal structure. Most of them located on the leaflet surface, at the areas of collagen destruction, and near calcium deposits. Monocytes were the predominant cell fraction on the leaflet surface whilst immune (macrophages, multinucleated giant cells, plasma cells, neutrophils) and connective tissue (fibroblasts, fibrocytes, endothelial, and smooth muscle cells) cells prevailed at the areas of collagen destruction and near calcium deposits. Calcification of the leaflets was accompanied by cellular infiltration, therefore suggesting that pathological mineralization may be associated with cell-mediated processes.

scholarly journals Primary splenic diffuse large B-cell lymphoma with multinucleated giant cells in a horse

2021 ◽  
Vol 66 (No. 2) ◽  
pp. 76-79
Author(s):  
W Hananeh ◽  
R Al Rukibat ◽  
M Daradka
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Splenic Mass ◽  
Large B Cell Lymphoma ◽  
First Case ◽  
Large B Cell

A diagnosis of a diffuse splenic large B-cell lymphoma with multinucleated giant cells in a 5-year-old mare was made based upon the clinical, pathological, and immunohistochemical findings. The enormous primary splenic mass weighed 51.75 kg. To the best of our knowledge, this is the biggest reported splenic mass and the first case of an equine diffuse large B-cell lymphoma with multinucleated giant cells.

scholarly journals Inflammatory myofibroblastic tumours of the respiratory tract: A series of three cases with varying clinical presentations and treatment

2015 ◽  
Vol 143 (7-8) ◽  
pp. 458-463
Author(s):  
Dragana Tegeltija ◽  
Aleksandra Lovrenski ◽  
Goran Stojanovic ◽  
Milorad Bijelovic ◽  
Ivana Jelicic ◽  
...  
Keyword(s):  
Inflammatory Myofibroblastic Tumor ◽  
Plasma Cells ◽  
Lower Lobe ◽  
Inflammatory Cells ◽  
Complete Removal ◽  
Giant Cells ◽  
Multinucleated Giant Cells ◽  
Clinical Presentations ◽  
Choice Of Treatment ◽  
The Right

Introduction. Inflammatory myofibroblastic tumor in the respiratory system is a rare and controversial disease. It is macroscopically well-circumscribed, non-encapsulated, firm and usually a yellowish-white mass. Histologically it is composed of the following spindled and inflammatory cells: lymphocytes, plasma cells, and histiocytes, including Touton type multinucleated giant cells. Case Outline. The series included a 49-year-old man with a tracheal inflammatory myofibroblastic tumor who complained of hoarseness; a 42-year-old man who was coughing and had a blood-stained sputum, and inflammatory myofibroblastic tumor was in the right main and intermediate bronchus; and a 32-yearold man with chest pain and inflammatory myofibroblastic tumor as a solitary peripheral nodule in the left lower lobe. In all the cases, the tumor was resected bronchoscopically and surgically. Conclusion. Inflammatory myofibroblastic tumor of the lung and the trachea is rare. Complete resection, when possible, should be the choice of treatment. After the complete removal, prognosis is generally excellent and recurrences are rare.

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