Sexual dysfunction in newly diagnosed multiple sclerosis women

2008 ◽  
Vol 14 (4) ◽  
pp. 561-563 ◽  
Author(s):  
Vassilios Tzortzis ◽  
Konstantinos Skriapas ◽  
George Hadjigeorgiou ◽  
Iraklis Mitsogiannis ◽  
Konstantinos Aggelakis ◽  
...  

Objectives The aim of the study was to evaluate female sexuality in a selective population of newly diagnosed multiple sclerosis (MS) women. Materials and methods In this clinic-based study, 63 newly diagnosed consecutive women affected by definite MS were admitted. Disability and depression were evaluated with the expanded disability status scale (EDSS) and Beck depression inventory, respectively. Sexual function was evaluated with the female sexual function index (FSFI). A group of 61 healthy female volunteers with the same baseline characteristics were used as controls. Postmenopausal women and patients with other major concomitant neurological, endocrinological, vascular, gynecological, psychiatric disorders, use of medicines that can cause female sexual dysfunction (FSD) and disease-modifying drugs were excluded from the study. Results All the evaluated patients were ambulant with no major neurological impairment (mean EDSS score 2.5, range 0—3.5). None of the patients were considered clinically depressed, but some of them were sad or worried. According to the sexual history and FSFI scores, sexual dysfunction was diagnosed in 22 (34.9%) out of the 63 patients and in 13 (21.31%) out of the 61 healthy females ( P > 0.05). Conclusions In the newly diagnosed MS patients, FSD represent an important issue even though disability and other concomitant disorders affecting sexual function were excluded. Multiple Sclerosis 2008; 14: 561—563. http://msj.sagepub.com

2008 ◽  
Vol 14 (8) ◽  
pp. 1131-1136 ◽  
Author(s):  
DK Tepavcevic ◽  
J Kostic ◽  
ID Basuroski ◽  
N Stojsavljevic ◽  
T Pekmezovic ◽  
...  

Objective Sexual dysfunction (SD) is a common but often overlooked symptom in multiple sclerosis (MS). The aim of this study was to estimate the frequency, type, and intensity of SD in our patients with MS and to investigate its influence on all the domains of quality of life. Methods The study population comprised a cohort of 109 patients with MS (McDonald's criteria, 2001). SD was quantified by a Szasz sexual functioning scale. Health-related quality of life was measured by a disease-specific instrument MSQoL-54 (Serbian version). Results The presence of at least one symptom of SD was found in about 84% of the men and in 85% of the women. The main complaints in women were reduced libido, difficulties in achieving orgasm, and decreased vaginal lubrication; in men, the main complaints were reduced libido, incomplete erections, and premature ejaculation. In women, statistically significant negative correlations between the presence and level of SD and quality of life domains were reached for all subscales ( P < 0.01), except for the Pain subscale ( P = 0.112). In men, negative correlations were also observed for all domains, but they were statistically significant for physical health, physical role limitations, social function, health distress, sexual function, and sexual function satisfaction ( P < 0.01). We found that the presence of all the analyzed types of sexual problems statistically significantly lowered scores on the sexual function and the sexual function satisfaction subscales in both men and women ( P < 0.01). The most prominent impact on both domains was observed for the total loss of erection in men and for anorgasmia in women. Conclusions Our results reveal that frequent occurrence of SD in MS patients prominently affects all aspects of their quality of life.


2020 ◽  
Author(s):  
Jennifer Potter

Sexuality is important to women of all ages. Although changes in sexual function occur with aging, hormonal transitions, illness, the use of medications, and disability, many women can maintain a satisfying sex life by making appropriate adaptations. Clinicians who take the time to obtain a complete and careful sexual history and perform a pertinent physical examination can help the majority of women who present with sexual complaints. Effective treatment must address the contribution of psychological, relationship, and biologic factors and often requires the collaboration of physicians and psychotherapists, as well as sex and physical therapists in many circumstances. Simply initiating a discussion about sexual concerns is frequently the most valuable aspect of treatment for women and their partners. Also useful are provision of basic education about normal female genital anatomy and sexual function across the lifespan; permission to explore masturbation, erotica, and versatile sexual techniques, as well as nongenital pleasuring; information about lubricants; and the prescription of estrogen in the setting of vulvovaginal atrophy. There are as yet no approved agents to treat the biologic component of hypoactive sexual desire. However, it may be appropriate to consider using androgen supplementation in patients with surgical menopause, as well as the addition of bupropion in patients taking selective serotonin reuptake inhibitors (SSRIs). This review discusses the epidemiology of female sexual disorders, the female sexual response and sexual behavior, and the diagnosis and management of specific sexual disorders, including desire, arousal, orgasm, and sexual-pain problems.  This review contains 4 figures, 41 tables, and 96 references. Keywords: Sexual dysfunction disorder, arousal, orgasm, desire, dyspareunia, vulvodynia, vestibulitis, vaginismus


Urology ◽  
2007 ◽  
Vol 70 (3) ◽  
pp. 74
Author(s):  
K. Skriapas ◽  
C. Konstantinidis ◽  
V. Tzortzis ◽  
G. Hadjigeorgiou ◽  
M. Samarinas ◽  
...  

2016 ◽  
Vol 34 (3_suppl) ◽  
pp. 87-87
Author(s):  
Gerard Edward Heath ◽  
Pamela Fairchild ◽  
Mitchell Berger ◽  
Anagha Tolpadi ◽  
Christina Chapman ◽  
...  

87 Background: Following radiation therapy (RT), gynecologic oncology patients report high rates of sexual dysfunction. However, little is known regarding communication of sexual health among these patients and their healthcare providers. The aim of this study was to assess the beliefs/attitudes of patients regarding sexual history taking. Methods: Survey results were obtained from 75 women who presented for follow up care for gynecologic cancers in the radiation oncology department. The surveys assessed patient beliefs about sexual health and its impact on overall quality of life, the role practitioners should play in obtaining an accurate sexual history, and preferences and level of embarrassment regarding sexual history collection. Overall level of sexual functioning was assessed using the Female Sexual Function Index (FSFI). Chi-squared tests were used to analyze categorical variables and logistic regression modeling was used to predict agreement with survey statements. Results: Most subjects were white and married with a mean FSFI score of 9.9 [(SD = 10.3) sexual dysfunction is defined as < 26.5]. 78.7% agreed that sexual function is an important component of overall health, and only 12.0% reported embarrassment about discussing their sexual health with healthcare providers. 62.79% agreed that medical providers should take a sexual history on a regular basis. However, 58.7% and 22.7% of women report never or almost never being asked about their sexual health by their primary care physician or Ob/Gyn, respectively. Approximately two-thirds of women expressed a preference to have a female provider obtain their sexual health history. Conclusions: Gynecologic cancer patients s/p RT report low sexual function scores. A majority agree that sexual function is essential to overall health. They report little embarrassment regarding discussions of sexual health, yet, note limited discussion about the topic with their healthcare providers. This work highlights the need for improvements in communication about sexual health. We suggest that healthcare providers caring for women with gynecologic cancers should more regularly inquire about their patients’ sexual health and function.


2014 ◽  
Vol 20 (13) ◽  
pp. 1761-1768 ◽  
Author(s):  
AC Lúcio ◽  
CAL D’Ancona ◽  
MHBM Lopes ◽  
MC Perissinotto ◽  
BP Damasceno

Background: Sexual dysfunction (SD) affects up to 80% of multiple sclerosis (MS) patients and pelvic floor muscles (PFMs) play an important role in the sexual function of these patients. Objectives: The objective of this paper is to evaluate the impact of a rehabilitation program to treat lower urinary tract symptoms on SD of women with MS. Methods: Thirty MS women were randomly allocated to one of three groups: pelvic floor muscle training (PFMT) with electromyographic (EMG) biofeedback and sham neuromuscular electrostimulation (NMES) (Group I), PFMT with EMG biofeedback and intravaginal NMES (Group II), and PFMT with EMG biofeedback and transcutaneous tibial nerve stimulation (TTNS) (Group III). Assessments, before and after the treatment, included: PFM function, PFM tone, flexibility of the vaginal opening and ability to relax the PFMs, and the Female Sexual Function Index (FSFI) questionnaire. Results: After treatment, all groups showed improvements in all domains of the PERFECT scheme. PFM tone and flexibility of the vaginal opening was lower after the intervention only for Group II. All groups improved in arousal, lubrication, satisfaction and total score domains of the FSFI questionnaire. Conclusion: This study indicates that PFMT alone or in combination with intravaginal NMES or TTNS contributes to the improvement of SD.


2021 ◽  
Vol 17 ◽  
Author(s):  
Negin Sayari ◽  
Katayon Vakilian ◽  
Zohre Khalajinia ◽  
Seyyed Amir Hejazi ◽  
Mostafa Vahedian

Aims: Improving sexual function in women with disability such as multiple sclerosis was aimed. Background: Sexual dysfunction and the consequent low satisfaction is very common in females with Multiple Sclerosis (MS). Objectives: This study aimed to investigate the effectiveness of Relationship Enhancement Therapy (REP) on sexual function and satisfaction of females with MS. Methods: the present study was an educational design with two groups, in which 44 females with MS participated and their spouses (N= 88) participated and randomly divided in two groups of intervention (N= 22 couples) and control (N= 22 couples). They signed written consent forms and were included in the project. The intervention group received the REP in six 90-minute sessions. The groups completed standard questionnaires of sexual dysfunction and sexual satisfaction in three stages of pretest-posttest and 3 months later. The Descriptive and inferential statistics (Two- way repeated measures ANOVA, chi-square, t-test and Mann-Whitney U test) were used to analyze data. Results: The results of analysis showed that there was a clinically significant difference between the scores of sexual dysfunction in different phases of the assessment between two groups (p <0.05). Also sexual satisfaction was higher in the intervention group vs. in the control (p <0.05). Conclusion: according to the findings, marital enrichment program was effective in improvement of sexual function and sexual satisfaction of females with multiple sclerosis. It is recommended to healthcare providers to use enrichment alongside medical services to improve patients' sexual life.


2004 ◽  
Vol 10 (4) ◽  
pp. 455-461 ◽  
Author(s):  
Diane Borello-France ◽  
Wendy Leng ◽  
Margie O'Leary ◽  
Macrina Xavier ◽  
Janet Erickson ◽  
...  

Objective: Genitourinary dysfunction is common in women with multiple sclerosis (MS), yet few studies have evaluated the association between bladder and sexual dysfunction in these women. The aim of this study was to determine factors, including demographic and bladder function, associated with sexual dysfunction in a sample of women with MS. Methods: One hundred and thirty-three women with MS completed questionnaires related to overall heath status, bladder function and sexual function. Response frequencies and percentages were calculated for questionnaire responses. Multivariate logistic regression analyses were performed to determine predictors of sexual dysfunction. Results: Sixty-one per cent of the sample indicated that they had a problem with bladder control. Forty-seven per cent of respondents indicated that their neurological problems interfered with their sex life. Over 70% of the sample reported that they enjoyed, felt aroused and experienced orgasm during sexual activity. Not having a sexual partner and the indication of bothersome neurological problems were the best predictors of sexual dysfunction. Interestingly, patients bothered by their urge incontinence had higher levels of orgasm compared to women not bothered by urge incontinence. Conclusions: Although over half of the women reported voiding symptoms, most still enjoyed, felt aroused and could experience orgasm. Neurological symptoms and lacking a sexual partner emerged as the best predictors of sexual dysfunction. Urge incontinence may not be a risk factor for anorgasm. Our findings elucidate the complex nature of sexual dysfunction in women with MS.


1999 ◽  
Vol 5 (6) ◽  
pp. 418-427 ◽  
Author(s):  
M Zorzon ◽  
R Zivadinov ◽  
A Bosco ◽  
L Monti Bragadin ◽  
R Moretti ◽  
...  

Sexual dysfunction is a very important but often overlooked symptom of multiple sclerosis. To investigate the type and frequency of symptoms of sexual dysfunction in patient suffering from multiple sclerosis, we performed a case-control study comparing 108 unselected patient with definite multiple sclerosis, 97 patient with chronic disease and 1 10 healthy individuals with regard to sexual function, sphincteric function, physical disorders impeding sexual activity and the impact of sexual dysfunction on social life. Information has been collected from a face-to-face structured interview performed by a doctor of the same gender as the patient. The disability, the cognitive performances, the psychiatric conditions and the psychological profile of patien t a nd co ntrols have bee n assessed. Sexul a dysfu nction was prese nt in 73.1% of cases, in 39.2% of chronic disease co ntrols and in 12.7% of h e althy co ntrols (P < 0.000 1). Male cases reported symptoms of sexual dysfunction more freq ue ntly th an female cases (P <0.002). Symptoms of sexual dysfunction more commonly reported in patient with multiple scerosis were anorgasmia or hyporgasmia (37.1%), decreased vaginal lubrication (35.7%) and reduced libido (31.4%) in women, and impotence or erectile dysfunction (63.2%), ejaculatory dysfunction and/or orgasmic dysfunction (50%) and reduced libido (39.5%) in men. Seventy-five per cent of cases, 51.% of chronic disease controls and 28.2% of healthy controls (P <0.0001) experienced symptoms of sphincteric dysfunction. In conldusion, a substantial part of our sample of patient with multiple sclerosis reported symptoms of sexual and sphincteric dysfunction. Both sexual and sphincteric dysfunction were significantly more common in patient with multiple sclerosis than in either control group. Our findings suggest that a peculiar damage of the structures involved in sexual function is responsible for the dysfunction in patient with multiple scerosis, but the highly significant lower frequency of symptoms of depression and anxiety in healthy controls may also imply a possible causative role of psychological factors.


2018 ◽  
Vol 80 (1-2) ◽  
pp. 34-41 ◽  
Author(s):  
Katharina M. Hösl ◽  
Martina Deutsch ◽  
Ruihao Wang ◽  
Sankanika Roy ◽  
Klemens Winder ◽  
...  

Background: In women with multiple sclerosis (MS), depression and sexual dysfunction (SD) are common. Whether SD promotes depression or vice versa remains unclear despite therapeutic relevance. Therefore, we aimed to assess whether SD more likely triggers depression or vice versa. Methods: In 83 female MS patients and 21 age-matched healthy women, we assessed depression, using the Beck Depression Inventory-V (BDI-V), and SD using the Female Sexual Function Index (FSFI). We diagnosed depression with BDI-V-scores >35 and SD with FSFI scores < 26.55. We divided patients into groups with and without SD, with and without depression. Between groups, we compared prevalence of SD and depression (Fisher’s-exact-test), age, MS-duration, MS-severity, BDI-V-, and FSFI scores (Mann-Whitney U-test; significance: p < 0.05). Results: A total of 37/83 MS patients and 1/21 controls had SD; 28/83 patients and 3/21 controls had depression; 51.4% patients with SD but only 19.6% without SD had depression (p = 0.003). SD was present in 67.9% depressed and 32.7% non-depressed patients. BDI-V-scores were higher in patients with SD than in patients without SD. FSFI scores were lower in depressed than non-depressed patients. Conclusion: In conclusion, SD was more common than depression. SD afflicted 67.9% depressed MS patients and was also more common in non-depressed MS patients than controls. SD may occur independently from depression while increased depressiveness seems linked to coexistent SD.


Author(s):  
V. Tzortzis ◽  
K. Skriapas ◽  
G. Hadjigeorgiou ◽  
I. Mitsogiannis ◽  
K. Aggelakis ◽  
...  

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