scholarly journals Rainbow of colors: Inspissated bile syndrome secondary to hemolytic disease of the newborn and concomitant serum dynamics

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110254
Author(s):  
Veronica Mugarab Samedi ◽  
Mehrieh Rahimi ◽  
Kaartigean Kalaniti ◽  
Martha Lyon ◽  
Sibasis Daspal

The recent clinical experience with hemolytic disease of the newborn and its post-icteric sequelae is limited among high-income countries because of nearly over four decades of effective prevention care. In this case, we will discuss the sequelae of a baby born with hemolytic disease of the newborn to an Rh negative mother with no prenatal care from remote northern Saskatchewan. Inspissated bile syndrome is a rare but serious complication of hemolytic disease of the newborn. The concentration of hemolytic products parallels with serum color changes.

1975 ◽  
Vol 292 (19) ◽  
pp. 1014-1016 ◽  
Author(s):  
Vincent J. Freda ◽  
John G. Gorman ◽  
William Pollack ◽  
Edward Bowe

1999 ◽  
Vol 5 (1_suppl) ◽  
pp. 14-17 ◽  
Author(s):  
Miklós Tõrõk ◽  
Zsuzsa Turi ◽  
Ferenc Kovács

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Emily W. Harville ◽  
Gloria P. Giarratano ◽  
Pierre Buekens ◽  
Eurydice Lang ◽  
Jennifer Wagman

Abstract Background Congenital syphilis is completely preventable through screening and treatment, but rates have been rising in the United States. Certain areas are at particularly high risk. We aimed to assess attitudes, knowledge, and barriers around effective prevention of congenital syphilis among health care providers and community women potentially at risk. Methods Two parallel studies were conducted: in-depth interviews with health care providers and focus groups with community women in the area of Baton Rouge, Louisiana. Each group was questioned about their experience in providing or seeking prenatal care, knowledge and attitudes about congenital syphilis, sources of information on testing and treatment, perceptions of risk, standards of and barriers to treatment. Results were transcribed into QSR NVivo V10, codes developed, and common themes identified and organized. Results Providers identified delays in testing and care, lack of follow-through with partner testing, and need for community connection for prevention, as major contributors to higher rates of congenital syphilis. Women identified difficulties in accessing Medicaid contributing to delayed start of prenatal care, lack of transportation for prenatal care, and lack of knowledge about testing and prevention for congenital syphilis. Conclusions Providers and community members were in broad agreement about factors contributing to higher rates of congenital syphilis, although some aspects were emphasized more by one group or another. Evidence-based interventions, likely at multiple levels, need to be tested and implemented to eliminate congenital syphilis.


2021 ◽  
pp. 140349482110477
Author(s):  
Simone Gad Kjeld ◽  
Maja Bæksgaard Jørgensen ◽  
Maria Aundal ◽  
Lotus Sofie Bast

Aims: Smoking in youth remains a major public health issue. As increasing tobacco prices is considered one of the most effective prevention strategies, examining youth’s responsiveness to price changes on cigarettes will provide crucial knowledge. This study aims systematically to review research examining the price elasticity of demand for cigarettes among youths (<30 years of age) in high-income countries. Methods: Searches were conducted in three databases (Web of Science, Pubmed and Scopus). Inclusion criteria were publications within the past 10 years (2011–2021) written in English and with a population of youths below 30 years of age, concerning price elasticity of demand for cigarettes and from high-income countries. Searches were screened by two independent reviewers and the quality of studies was assessed using a quality assessment tool. Results: Four outcomes related to price elasticity of demand for cigarettes were examined in six studies included in this review; that is, cigarette initiation, consumption, prevalence and cessation. Overall, findings indicate that increasing tobacco prices affect youth tobacco use. The effect was associated with gender and age; young women were more price sensitive concerning smoking initiation, whereas young men were more price sensitive concerning cigarette prevalence and consumption. Moreover, younger age was associated with higher price elasticity. Conclusions: Estimates for price elasticity varied across the included studies. This may be caused by differences in data sources, collection methods used and country of origin. Most included studies were of older date. Therefore, to make reliable predictions of the expected effects of increased tobacco prices, further examinations of up-to-date and locally embedded measures are required.


2018 ◽  
Vol 131 ◽  
pp. 176S
Author(s):  
Matt Tschirgi ◽  
Betsy Swope ◽  
Catherine Terhaar ◽  
Lindsay Dohany ◽  
Christina Settler

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
D Tsygankova ◽  
G.V Artamonova ◽  
O.L Barbarash

Abstract Introduction Recent data indicate that the population diet quality is related to its socio-economic status. Identification of dietary characteristics depending on the population status will help to determine effective prevention strategies diet-related diseases. Objective To assess the population dietary pattern depending on their income level, education and marital status. Methods A total of 1,600 people aged 35–70 years were examined in accordance with the program of Prospective Urban Rural Epidemiology (PURE) study. All participants were interviewed to determine the level of education, income, marital status and dependents. Diet was assessed using the Food Frequency Questionnaire. During data processing, products with similar characteristics were grouped into categories. To calculate the consumption frequency of particular group of products, following points were assigned: never, less than once a month – 1 point; 1–3 times a month – 2; once a week – 3; 2–4 times a week – 4; 5–6 times a week – 5; once a day – 6; 2–3 times a day – 7; 4–5 times a day – 8; more than 6 times a day – 9 points. Statistical processing was carried out using a software package Statistica 6.0. Results Women were more likely to eat fruits (27.37±8.50 points, p=0.000), vegetables (95.56±22.01 points, p=0.000) and cereals (16.02±4.08, p=0,000) than men. The consumption of the above mentioned products increased with age. In comparison with rural population, urban population were more likely to eat fruits in season (27.0±8.66 and 25.8±7.99 points respectively, p=0.028) and nuts (2.25±1.37 and 1.98±1.30 points, p=0.000). University-educated responders compared to less educated respondents more often used the following product groups: grain/cereals (16.15±4.06 and 15.22±4.20 points, p=0.000), nuts (2.40±1.40 and 2.04±1.31 points, p=0.000). High-income respondents compared with low-income subjects were more likely to eat fruits in season (27.75±8.55 and 26.26±8.41 points, p=0.001), vegetables out of season (76.83±18.57 and 74.99±18.49 points, p=0.047), products of animal origin (47.23±10.35 and 45.56±9.99 points, p=0.005). High-income respondents preferred sweets less than respondents with a low-income level. In contrast to single respondents, people living with a family were more like to consume fruits in season (27.00±8.43 and 26.01±8.53, p=0.038), heat-treated vegetables (32.08±8.40 and 30.73±8.55, p=0.001), animal products (47.51±9.84 and 43.06±10.00 points, p=0.000), soups (17.13±4.55 and 16.17±4.61 points, p=0.000), potatoes (25.49±5.33 and 24.20±6.04 points, p=0.000) and bakery products (40.93±7.09 and 39.93±8.04, p=0.008). Conclusion The urban population with a high level of income, educated at university and having a family, as well as women and older age group responders, more often ate fruits and vegetables, cereals, nuts than respondents living in rural areas with a low level of income and education or without family. Funding Acknowledgement Type of funding source: Other. Main funding source(s): Pfizer initiative reserch grant


BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e017321
Author(s):  
Marc Bardou ◽  
Bruno Crépon ◽  
Anne-Claire Bertaux ◽  
Aurélie Godard-Marceaux ◽  
Astrid Eckman-Lacroix ◽  
...  

IntroductionPrenatal care is recommended during pregnancy to improve neonatal and maternal outcomes. Women of lower socioeconomic status (SES) are less compliant to recommended prenatal care and suffer a higher risk of adverse perinatal outcomes. Several attempts to encourage optimal pregnancy follow-up have shown controversial results, particularly in high-income countries. Few studies have assessed financial incentives to encourage prenatal care, and none reported materno-fetal events as the primary outcome. Our study aims to determine whether financial incentives could improve pregnancy outcomes in women with low SES in a high-income country.Methods and analysisThis pragmatic cluster-randomised clinical trial includes pregnant women with the following criteria: (1) age above 18 years, (2) first pregnancy visit before 26 weeks of gestation and (3) belonging to a socioeconomically disadvantaged group. The intervention consists in offering financial incentives conditional on attending scheduled pregnancy follow-up consultations. Clusters are 2-month periods with random turnover across centres. A composite outcome of maternal and neonatal morbidity and mortality is the primary endpoint. Secondary endpoints include maternal or neonatal outcomes assessed separately, qualitative assessment of the perception of the intervention and cost-effectiveness analysis for which children will be followed to the end of their first year through the French health insurance database. The study started in June 2016, and based on an expected decrease in the primary endpoint from 18% to 14% in the intervention group, we plan to include 2000 women in each group.Ethics and disseminationEthics approval was first gained on 28 September 2014. An independent data security and monitoring committee has been established. Results of the main trial and each of the secondary analyses will be submitted for publication in a peer-reviewed journal.Trial registration numberNCT02402855; pre-results.


2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Sergey Moskvin ◽  
Evgeniy Askhadulin ◽  
Andrey Kochetkov

Objectives. The aim of the article is to justify the application of low-level laser therapy (LLLT) to prevent the development of endothelial dysfunction in COVID-19 patients. The results of treating and rehabilitating patients with COVID-19 and prevention of the disease using low-level laser therapy (LLLT) are evaluated. Methods. A literature review is conducted on mechanisms of vascular homeostasis regulation, biomodulating effect of laser light, and LLLT methods for preventing endothelial dysfunction. A total of 106 patients were treated in two COVID-19 healthcare centers in Russia. 22 patients with SARS (+) pneumonia at the stage of resolving the pathological lesion were admitted to rehabilitation using pulsed IR laser. 14 patients with acute forms of COVID-19 were treated using LASMIK device: wavelength 904 nm, pulsed mode, externally and ILBI-525 (intravenous laser blood illumination) + LUVBI (ultraviolet laser blood illumination). 70 persons underwent preventive courses of noninvasive LLLT. Results. It was shown that LLLT is effective in preventing the development of endothelial dysfunction. Clinical experience demonstrated good tolerability of the treatment, improvement in sputum discharge, and an improvement in overall health. The severity of general hypoxia decreased by the 5th procedure. The procedures for prevention of the disease were well tolerated; there were no cases of COVID-19. Conclusion. Low-level laser therapy is a justified treatment method that promotes lung tissue regeneration and mitigates the consequences of the disease. The obtained results confirm that LLLT can be used for the effective prevention and treatment of COVID-19 patients.


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