scholarly journals Precision Medicine for Breath-Focused Mind-Body Therapies for Stress and Anxiety: Are We Ready Yet?

2021 ◽  
Vol 10 ◽  
pp. 216495612098612
Author(s):  
Helen Lavretsky ◽  
Jack L Feldman PhD
Keyword(s):  
Public Health ◽  
Emotion Regulation ◽  
Precision Medicine ◽  
Breathing Control ◽  
Human Models ◽  
Breathing Techniques

In this viewpoint, we present an argument for transdisciplinary “precision medicine” approaches that combine studies of basic neurobiology of breathing in animal and human models of stress that can help characterize physiological and neural biomarkers and mechanisms of breathing control and emotion regulation in humans. Such mechanistic research is fundamental for the development of more effective and mechanism-based mind-body therapies. The potential for this research to positively impact public health is high, as breathing techniques are inexpensive, accessible, and cross-culturally accepted, with fewer complications then observed with other standard therapies for stress-related disorders.

scholarly journals Advancing precision public health using human genomics: examples from the field and future research opportunities

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Megan C. Roberts ◽  
Alison E. Fohner ◽  
Latrice Landry ◽  
Dana Lee Olstad ◽  
Amelia K. Smit ◽  
...  
Keyword(s):  
Public Health ◽  
Precision Medicine ◽  
Behavioral Science ◽  
Public Health Research ◽  
Future Research ◽  
Human Genomics ◽  
Precision Public Health ◽  
Genomics Research ◽  
Health Initiatives ◽  
Public Health Initiatives

AbstractPrecision public health is a relatively new field that integrates components of precision medicine, such as human genomics research, with public health concepts to help improve population health. Despite interest in advancing precision public health initiatives using human genomics research, current and future opportunities in this emerging field remain largely undescribed. To that end, we provide examples of promising opportunities and current applications of genomics research within precision public health and outline future directions within five major domains of public health: biostatistics, environmental health, epidemiology, health policy and health services, and social and behavioral science. To further extend applications of genomics within precision public health research, three key cross-cutting challenges will need to be addressed: developing policies that implement precision public health initiatives at multiple levels, improving data integration and developing more rigorous methodologies, and incorporating initiatives that address health equity. Realizing the potential to better integrate human genomics within precision public health will require transdisciplinary efforts that leverage the strengths of both precision medicine and public health.

scholarly journals Generic Cost-Effectiveness Models: A Proof of Concept of a Tool for Informed Decision-Making for Public Health Precision Medicine

2018 ◽  
Vol 21 (5-6) ◽  
pp. 217-227 ◽  
Author(s):  
Susan R. Snyder ◽  
Jing Hao ◽  
Larisa H. Cavallari ◽  
Zhi Geng ◽  
Amanda Elsey ◽  
...  
Keyword(s):  
Public Health ◽  
Decision Making ◽  
Cost Effectiveness ◽  
Precision Medicine ◽  
Informed Decision ◽  
Informed Decision Making ◽  
Proof Of Concept

scholarly journals Artificial Intelligence–Aided Precision Medicine for COVID-19: Strategic Areas of Research and Development (Preprint)

2020 ◽  
Author(s):  
Enrico Santus ◽  
Nicola Marino ◽  
Davide Cirillo ◽  
Emmanuele Chersoni ◽  
Arnau Montagud ◽  
...  
Keyword(s):  
Public Health ◽  
Artificial Intelligence ◽  
Health Care ◽  
Research And Development ◽  
Precision Medicine ◽  
Patient Outcomes ◽  
Medical Literature ◽  
Drug Repurposing ◽  
Public Health Systems ◽  
Improve Patient

UNSTRUCTURED Artificial intelligence (AI) technologies can play a key role in preventing, detecting, and monitoring epidemics. In this paper, we provide an overview of the recently published literature on the COVID-19 pandemic in four strategic areas: (1) triage, diagnosis, and risk prediction; (2) drug repurposing and development; (3) pharmacogenomics and vaccines; and (4) mining of the medical literature. We highlight how AI-powered health care can enable public health systems to efficiently handle future outbreaks and improve patient outcomes.

scholarly journals Importance of Genetic Studies of Cardiometabolic Disease in Diverse Populations

2020 ◽  
Vol 126 (12) ◽  
pp. 1816-1840
Author(s):  
Lindsay Fernández-Rhodes ◽  
Kristin L. Young ◽  
Adam G. Lilly ◽  
Laura M. Raffield ◽  
Heather M. Highland ◽  
...  
Keyword(s):  
Public Health ◽  
Precision Medicine ◽  
Association Studies ◽  
Evidence Base ◽  
Cardiometabolic Disease ◽  
Polygenic Risk Score ◽  
Genome Wide Association Studies ◽  
Genetic Studies ◽  
Genome Wide ◽  
Current Variation

Genome-wide association studies have revolutionized our understanding of the genetic underpinnings of cardiometabolic disease. Yet, the inadequate representation of individuals of diverse ancestral backgrounds in these studies may undercut their ultimate potential for both public health and precision medicine. The goal of this review is to describe the imperativeness of studying the populations who are most affected by cardiometabolic disease, to the aim of better understanding the genetic underpinnings of the disease. We support this premise by describing the current variation in the global burden of cardiometabolic disease and emphasize the importance of building a globally and ancestrally representative genetics evidence base for the identification of population-specific variants, fine-mapping, and polygenic risk score estimation. We discuss the important ethical, legal, and social implications of increasing ancestral diversity in genetic studies of cardiometabolic disease and the challenges that arise from the (1) lack of diversity in current reference populations and available analytic samples and the (2) unequal generation of health-associated genomic data and their prediction accuracies. Despite these challenges, we conclude that additional, unprecedented opportunities lie ahead for public health genomics and the realization of precision medicine, provided that the gap in diversity can be systematically addressed. Achieving this goal will require concerted efforts by social, academic, professional and regulatory stakeholders and communities, and these efforts must be based on principles of equity and social justice.

scholarly journals Precision Public Health for the Era of Precision Medicine

2016 ◽  
Vol 50 (3) ◽  
pp. 398-401 ◽  
Author(s):  
Muin J. Khoury ◽  
Michael F. Iademarco ◽  
William T. Riley
Keyword(s):  
Public Health ◽  
Precision Medicine ◽  
Precision Public Health

Sarcopenia: Beyond Muscle Atrophy and into the New Frontiers of Opportunistic Imaging, Precision Medicine, and Machine Learning

2018 ◽  
Vol 22 (03) ◽  
pp. 307-322 ◽  
Author(s):  
Leon Lenchik ◽  
Robert Boutin
Keyword(s):  
Public Health ◽  
Machine Learning ◽  
Precision Medicine ◽  
Muscle Atrophy ◽  
State Of The Art ◽  
The State ◽  
Future Directions ◽  
Common Diagnosis ◽  
The Impact

AbstractAs populations continue to age worldwide, the impact of sarcopenia on public health will continue to grow. The clinically relevant and increasingly common diagnosis of sarcopenia is at the confluence of three tectonic shifts in medicine: opportunistic imaging, precision medicine, and machine learning. This review focuses on the state-of-the-art imaging of sarcopenia and provides context for such imaging by discussing the epidemiology, pathophysiology, consequences, and future directions in the field of sarcopenia.

Public Health in the Precision-Medicine Era

2015 ◽  
Vol 373 (6) ◽  
pp. 499-501 ◽  
Author(s):  
Ronald Bayer ◽  
Sandro Galea
Keyword(s):  
Public Health ◽  
Precision Medicine
Sign in / Sign up

Export Citation Format

Share Document