Anticancer Drug Prescription Patterns in Japan: Future Directions in Cancer Therapy

2018 ◽  
Vol 52 (6) ◽  
pp. 718-723 ◽  
Author(s):  
Shoyo Shibata ◽  
Maiko Matsushita ◽  
Yoshimasa Saito ◽  
Takeshi Suzuki
Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 723
Author(s):  
Valerie J. Carpenter ◽  
Tareq Saleh ◽  
David A. Gewirtz

Senolytics represent a group of mechanistically diverse drugs that can eliminate senescent cells, both in tumors and in several aging-related pathologies. Consequently, senolytic use has been proposed as a potential adjuvant approach to improve the response to senescence-inducing conventional and targeted cancer therapies. Despite the unequivocal promise of senolytics, issues of universality, selectivity, resistance, and toxicity remain to be further clarified. In this review, we attempt to summarize and analyze the current preclinical literature involving the use of senolytics in senescent tumor cell models, and to propose tenable solutions and future directions to improve the understanding and use of this novel class of drugs.


2009 ◽  
Vol 42 (02) ◽  
pp. 66-71 ◽  
Author(s):  
S. Weinbrenner ◽  
H.-J. Assion ◽  
T. Stargardt ◽  
R. Busse ◽  
G. Juckel ◽  
...  

2020 ◽  
Vol 50 (3) ◽  
Author(s):  
Ritesh Bhole ◽  
Shradha Jadhav ◽  
Yogesh B. Zambare ◽  
Rupesh V. Chikhale ◽  
Chandrakant Bonde

2011 ◽  
Vol 12 (5) ◽  
pp. 681-691 ◽  
Author(s):  
Laetitia Albertini ◽  
Gérard Siest ◽  
Elise Jeannesson ◽  
Sophie Visvikis-Siest

Nanoscale ◽  
2019 ◽  
Vol 11 (14) ◽  
pp. 6519-6532 ◽  
Author(s):  
Lucie Reinišová ◽  
Soňa Hermanová ◽  
Martin Pumera

A biomedical perspective is used to assess micro/nanomotor-based anticancer drug delivery systems with recommendations for their effective future development.


Sign in / Sign up

Export Citation Format

Share Document