scholarly journals Salicylate blockade of granulocyte adherence and the inflammatory response to experimental peritonitis

Blood ◽  
1979 ◽  
Vol 53 (5) ◽  
pp. 1018-1022
Author(s):  
PJ Spagnuolo ◽  
JJ Ellner
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Inflammatory Response ◽  
Sodium Salicylate ◽  
Nylon Fiber ◽  
Intraperitoneal Infection ◽  
And Staphylococcus Aureus ◽  
Human And Mouse

Aspirin profoundly inhibited the in vitro augmentation of human and mouse granulocyte adherence to nylon fiber induced by the bacterial products Escherichia coli endotoxin and Staphylococcus aureus culture filtrate. Granulocytes obtained from normal volunteers during the 48 hr following ingestion of aspirin did not respond normally to endotoxin stimulation. Furthermore, pretreatment of mice with sodium salicylate prior to intraperitoneal infection with Streptococcus pneumoniae impaired granulocyte exudation and resulted in uncontrolled bacteremia and greater lethality of infection.

scholarly journals Salicylate blockade of granulocyte adherence and the inflammatory response to experimental peritonitis

Blood ◽  
1979 ◽  
Vol 53 (5) ◽  
pp. 1018-1022 ◽  
Author(s):  
PJ Spagnuolo ◽  
JJ Ellner
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Streptococcus Pneumoniae ◽  
Inflammatory Response ◽  
Sodium Salicylate ◽  
Nylon Fiber ◽  
Intraperitoneal Infection ◽  
And Staphylococcus Aureus ◽  
Human And Mouse

Abstract Aspirin profoundly inhibited the in vitro augmentation of human and mouse granulocyte adherence to nylon fiber induced by the bacterial products Escherichia coli endotoxin and Staphylococcus aureus culture filtrate. Granulocytes obtained from normal volunteers during the 48 hr following ingestion of aspirin did not respond normally to endotoxin stimulation. Furthermore, pretreatment of mice with sodium salicylate prior to intraperitoneal infection with Streptococcus pneumoniae impaired granulocyte exudation and resulted in uncontrolled bacteremia and greater lethality of infection.

scholarly journals Evaluation preliminary phytochemistry and antimicrobial activity of extracts in Eugenia uniflora L. on Escherichia coli and Staphylococcus aureus

2021 ◽  
Vol 10 (13) ◽  
pp. e329101320579
Author(s):  
Alexandre Horácio Couto Bittencourt ◽  
Jaqueline Souza Machado ◽  
Mariana Garcia da Silva ◽  
Braz Antônio Pereira Cosenza
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Eugenia Uniflora ◽  
E Coli ◽  
And Staphylococcus Aureus

Devido ao aumento da resistência de patógenos humanos e animais aos medicamentos atuais, pesquisas por novos antimicrobianos têm sido incentivadas, principalmente por meio de plantas medicinais. Eugenia uniflora L., conhecida como pitangueira, é popularmente utilizada com diversas funções terapêuticas, justificando estudos nesta espécie. Assim, os objetivos deste estudo foram avaliar a atividade antibacteriana “in vitro” de extratos de folhas e cascas de Eugenia uniflora L. sobre Escherichia coli e Staphylococcus aureus. Para as etapas de triagem fitoquímica e microbiologia, foram utilizadas as metodologias usuais nessas áreas para obtenção dos extratos e avaliação da atividade antibacteriana com uso de controle positivo e negativo. Os resultados obtidos mostraram que no extrato das folhas foi verificada a presença de saponinas, flavonóides, alcalóides e taninos, enquanto na casca foram obtidos apenas saponinas e alcalóides. Os extratos da folha e da casca foram capazes de inibir o crescimento de Stapylococcus aureus apenas, promovendo halos de inibição de meio de 19,4 mm e 14,4 mm, respectivamente. As análises permitiram concluir que os extratos apresentam metabólitos secundários interessantes e de grande potencial antimicrobiano e que esses extratos foram capazes de inibir apenas as cepas de S. aureus, sendo resistentes às cepas de E. Coli.

Compatibility of Cephalosporins and Aminogl Ycosides in Peritoneal Dialysis Fluid

1983 ◽  
Vol 3 (3) ◽  
pp. 128-129 ◽  
Author(s):  
Carol Loeppky ◽  
Eugene Tarka ◽  
E. Dale Everett
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Peritoneal Dialysis ◽  
In Vitro Studies ◽  
Dialysis Fluid ◽  
Peritoneal Dialysis Fluid ◽  
The Individual ◽  
And Staphylococcus Aureus

Often dialysis -associated peritonitis is treated before the results of cultures are known with a cephalosporin and an aminoglycoside in combination. Because there may be antagonism between the individual drugs in such combinations, we have investigated this possibility through the use of timed, killing curves in dialysate effluent. We tested various cephalosporins and aminoglycosides alone and in combination at concentrations usually instilled into the peritoneum and determined their activity against one strain each of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. The results of these in-vitro studies show no evidence of antagonism but rather suggest an additive effect as evidenced by more rapid killing.

In vitro bactericidal activity of diterpenoids isolated from Aframomum melegueta K.Schum against strains of Escherichia coli , Listeria monocytogenes and Staphylococcus aureus

2014 ◽  
Vol 151 (3) ◽  
pp. 1147-1154 ◽  
Author(s):  
Kenneth G. Ngwoke ◽  
Olivier Chevallier ◽  
Venasius K. Wirkom ◽  
Paul Stevenson ◽  
Christopher T. Elliott ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Listeria Monocytogenes ◽  
Bactericidal Activity ◽  
And Staphylococcus Aureus

The production of antibacterial tubing, sutures, and bandages by in situ precipitation of metallic salts

1991 ◽  
Vol 37 (6) ◽  
pp. 445-449 ◽  
Author(s):  
Samuel R. Farrah ◽  
Gregory W. Erdos
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Silver Ions ◽  
Silicone Tubing ◽  
Metallic Salts ◽  
Second Procedure ◽  
And Staphylococcus Aureus

Two procedures were used to modify gauze bandages, polyester sutures, silicone tubing, and polyvinyl chloride tubing. In one procedure, the materials were first modified by in situ precipitation of metallic hydroxides and then used to adsorb silver ions. In the second procedure, the materials were soaked in sodium pyrophosphate or sodium chloride, dried, and then soaked in silver nitrate. These procedures produced materials with silver deposited on the surface of the tubing and sutures and both on the surface and within the gauze fibers. The modified materials inhibited the growth of Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus in vitro. Key words: tubing, sutures, bandages, antibacterial.

scholarly journals Studies of antagonistic effect between Lactobacillus sakei on Escherichia coli, Listeria monocytogenes and Staphylococcus aureus

2012 ◽  
Vol 3 (1) ◽  
pp. 10-17
Author(s):  
Augustus Caeser Franke Portella ◽  
Raimundo Wagner de Souza Aguiar ◽  
Jefferson da Luz Costa ◽  
André Luís Lopes Da Silva ◽  
Gessiel Newton Scheidt
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Listeria Monocytogenes ◽  
Antagonistic Effect ◽  
Lactobacillus Sakei ◽  
E Coli ◽  
And Staphylococcus Aureus

A atividade antimicrobiana de uma cultura comercial probiótica  deLactobacillus  sakei  (ATCC  1521)  foi avaliada em termos de concentração celular (30, 42, 60, 78 e 90 mcg / ml, 105 - 107UFC/mL), temperatura de incubação (4, 10, 20, 30, 37 ° C) e pH inicial do meio de cultura (3.5, 4.0, 4.5, 5.0 e 5.5) contra três patógenos alimentares, Escherichia coli, Listeria monocytogenes e Staphylococcus aureus. O efeito antagônico da cultura probiótica in vitro foi realizada através da aplicação de método quantitativo espectrofotométrico. Os resultados indicaram que uma substância inibitória presente em caldo de cultura de 24 horas poderia ser vantajoso quando mantendo a cultura dominante durante fermentações mais prolongadas. Para a maior produção de ácido láctico (1,04%v/v), o período de incubação da bactéria em caldo MRS foi de 24 horas em condições aeróbicas e a 37 ºC, com um valor de pH mínimo do sobrenadante (3,5). Os dados sugerem que o sobrenadante pode ter atividade bacteriostática significativa contra E. coli,L. monocytogenes e S. aureus, e pode fornecer carnes curadas com um grau de protecção contra este microorganismo, particularmente se empregada com uma combinação de pH ácido, e de refrigeração adequada.

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