scholarly journals EHMTI-0386. Chronic subdural hematoma and spinal cerebrospinal fluid leak and in non-geriatric patients

2014 ◽  
Vol 15 (S1) ◽  
Author(s):  
J Beck ◽  
CT Ulrich ◽  
J Gralla ◽  
J Fichtner ◽  
C Fung ◽  
...  
2021 ◽  
Vol 12 ◽  
pp. 578
Author(s):  
Antonio Colamaria ◽  
Matteo Sacco ◽  
Savino Iodice ◽  
Nicola Pio Fochi ◽  
Francesco Carbone

Background: Chronic subdural hematoma (CSDH) represents the most common neurosurgical disease. Given the demographic shift toward an aging population, the overall incidence of this condition is increasing. Nevertheless, clarity in the pathophysiological process is yet to be made. Several etiological mechanisms have been proposed to initiate and consequently promote fluid collection in the subdural space. Traumatic injury of the bridging veins has long been considered the primum movens of the pathology but increasing evidence shows that trauma is not the only factor involved. Along with recent advances we sought to understand the role of the cerebrospinal fluid (CSF) in the buildup of the intense inflammatory reaction that characterizes CSDH. Methods: In the present study, we examined histological features of reactive membranes secondary to extracranial CSF leakage with CSDH-related membranes. Similarity and differences between the specimens were examined by means of light microscopy. Results: Histological similarities were consistently found between CSDH membranes and reactive membranes secondary to CSF leakage in the extracranial space. Activated histiocytes were highlighted in all specimens along with an intense inflammatory reaction. Conclusion: CSDH is most likely the result of a complex interaction among different pathophysiological events resulting from both traumatic and inflammatory etiologies. In the present work, we highlight how CSF leakage could be an early factor that leads to a cascade of events that culminates in CSDH formation.


2019 ◽  
Vol 14 (3) ◽  
pp. 44-47
Author(s):  
Anna Whalen-Browne ◽  
Kristyne Onizuka ◽  
Maria Tiboni ◽  
Ragini Srinivasan

ABSTRACTHeadaches in the post-partum period are common, while new seizures are not. While many causes of post-partum headache are benign, it can be difficult to determine which patients warrant a more comprehensive workup to investigate for serious causes, which may only present later with neurologic sequelae such as new seizures. We suggest that persistent post-dural puncture headaches in the context of intrapartum epidural anesthesia can be suggestive of a serious cause such as intracranial hypotension or subdural hematoma. We describe a case of a 28-year-old G1P1 female presenting with a first-time seizure at 19 days post-partum caused by subdural hematoma from a persistent cerebrospinal fluid leak. This was in the context of a history of typical post-dural puncture headache following delivery. RÉSUMÉLes maux de tête dans la période post-partum sont fréquents, alors que les nouvelles crises ne le sont pas. Bien que de nombreuses causes de céphalées post-partum soient bénignes, il peut être difficile de déterminer quels patients justifient un bilan plus complet pour rechercher les causes graves, qui peuvent ne se présenter que plus tard avec des séquelles neurologiques comme de nouvelles crises. Nous suggérons que les maux de tête persistants post-ponctionnels dans le contexte de l’anesthésie épidurale intra-partum peuvent suggérer une cause grave comme l’hypotension intracrânienne ou un hématome sous-dural. Nous décrivons le cas d’une femme G1P1 de 28 ans qui présente une première crise d’épilepsie 19 jours après l’accouchement causée par un hématome sous-dural causé par une fuite persistante de liquide céphalorachidien. C’était dans le contexte d’une histoire de céphalées typiques après une ponction post-durale après l’accouchement.


Skull Base ◽  
2009 ◽  
Vol 19 (S 02) ◽  
Author(s):  
E. Pasquini ◽  
G. Tenti ◽  
C. Bordonaro ◽  
P. Farneti ◽  
V. Sciarretta ◽  
...  

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