scholarly journals Study on the relationship of depression, anxiety, lifestyle and eating habits with the severity of reflux esophagitis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rongxin Wang ◽  
Jing Wang ◽  
Shuiqing Hu
Keyword(s):  
Quality Of Life ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Reflux Esophagitis ◽  
Eating Habits ◽  
Positive Correlation ◽  
Relationship Of ◽  
The Relationship

Abstract Background The etiology of reflux esophagitis (RE) is multi-factorial. This study analyzed the relationship of depression, anxiety, lifestyle and eating habits with RE and its severity and further explored the impact of anxiety and depression on patients’ symptoms and quality of life. Methods From September 2016 to February 2018, a total of 689 subjects at Xuanwu Hospital Capital Medical University participated in this survey. They were divided into the RE group (patients diagnosed with RE on gastroscopy, n = 361) and the control group (healthy individuals without heartburn, regurgitation and other gastrointestinal symptoms, n = 328). The survey included general demographic information, lifestyle habits, eating habits, comorbidities, current medications, the gastroesophageal reflux disease (GERD) questionnaire (GerdQ), the Patient Health Questionnaire-9 depression scale and the General Anxiety Disorder-7 anxiety scale. Results The mean age and sex ratio of the two groups were similar. Multivariate logistic regression analysis identified the following factors as related to the onset of RE (p < 0.05): low education level; drinking strong tea; preferences for sweets, noodles and acidic foods; sleeping on a low pillow; overeating; a short interval between dinner and sleep; anxiety; depression; constipation; history of hypertension; and use of oral calcium channel blockers. Ordinal logistic regression analysis revealed a positive correlation between sleeping on a low pillow and RE severity (p = 0.025). Depression had a positive correlation with the severity of symptoms (rs = 0.375, p < 0.001) and patients’ quality of life (rs = 0.306, p < 0.001), whereas anxiety showed no such association. Conclusions Many lifestyle factors and eating habits were correlated with the onset of RE. Notably, sleeping on a low pillow was positively correlated with RE severity, and depression was positively related to the severity of symptoms and patients’ quality of life.

scholarly journals Study on the relationship of depression, anxiety, lifestyle and eating habits to the severity of reflux esophagitis

2020 ◽  
Author(s):  
Rongxin Wang ◽  
Jing Wang ◽  
Shuiqing Hu
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Reflux Esophagitis ◽  
Eating Habits ◽  
Positive Correlation ◽  
Independent Risk Factors

Abstract Background: The etiology of reflux esophagitis (RE) is multi-factorial. This study aims to analyze the risk factors of the RE, its severity and further explore the impact of anxiety and depression on the patients' symptoms and quality of life. Methods: From September 2016 to February 2018, a total of 689 subjects at Xuanwu Hospital Capital Medical University participated in the survey. They were divided into RE group (patients diagnosed as RE on gastroscopy, n = 361) and control group (healthy individuals without heartburn, regurgitation and other typical symptoms, n = 328). The survey included general demographic data, lifestyle habits, eating habits, GERD questionnaire (GerdQ), PHQ-9 depression scale and GAD-7 anxiety scale. Results: The mean age and sex ratio of the two groups were similar. Multivariate logistic regression analysis showed that low education level, drinking strong tea, preference for sweets and acidic foods, overeating, short interval between dinner and sleep, anxiety, depression, sleeping on low pillow and constipation were independent risk factors for RE (p< 0.05). Ordinal logistic regression analysis showed positive correlation between sleeping on low pillow and the severity of RE (p=0.024). Depression had positive correlation with the severity of symptoms (rs=0.375，P<0.001) and the quality of life (rs=0.306，P<0.001), whereas anxiety had no such association. Conclusions: Many lifestyle and eating habits are independent risk factors for the development of RE. Sleeping on low pillow was positively correlated with the severity of RE. Depression was positively related to the severity of symptoms and the quality of life.

scholarly journals Sex differences in the relationship among alcohol, smoking, and Helicobacter pylori infection in asymptomatic individuals

2020 ◽  
Vol 48 (5) ◽  
pp. 030006052092603
Author(s):  
Wenzhi Wu ◽  
Marcis Leja ◽  
Vladislav Tsukanov ◽  
Zarrin Basharat ◽  
Dong Hua ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Alcohol Consumption ◽  
Logistic Regression Analysis ◽  
Helicobacter Pylori Infection ◽  
Multivariable Logistic Regression Analysis ◽  
H Pylori ◽  
Relationship Of ◽  
The Relationship

Objective We aimed to investigate the relationship of Helicobacter pylori infection with alcohol and smoking. Methods We conducted a cross-sectional study among participants who underwent health check-ups for H. pylori infection between January 2013 and March 2017. We subsequently investigated the relationship of H. pylori infection with alcohol and smoking. Results A total of 7169 participants were enrolled in this study. The overall prevalence of H. pylori infection was 55.2%. Participants with H. pylori infection were more likely to be older than those without H. pylori infection. For male participants with H. pylori infection, multivariable logistic regression analysis indicated that both smoking (odds ratio (OR): 1.61; 95% confidence interval (CI): 1.41–1.83) and alcohol consumption (OR: 1.30; 95% CI: 1.10–1.52) were independently positively associated with H. pylori infection. For female participants, multivariable logistic regression analysis indicated that both smoking (OR: 0.03; 95% CI: 0.02–0.07) and alcohol consumption (OR: 0.20; 95% CI: 0.12–0.33) were inversely significantly associated with H. pylori infection after adjustment for age. Conclusions Smoking and alcohol consumption were risk factors for male participants but these were protective factors for female individuals with H. pylori infection.

scholarly journals Variables associated with the post-treatment healing of lesions in patients with American cutaneous leishmaniasis in Paraná State, Brazil

2009 ◽  
Vol 45 (4) ◽  
pp. 841-847 ◽  
Author(s):  
Maria Teresinha Gomes Casavechia ◽  
Thaís Gomes Verzignassi Silveira ◽  
Ueslei Teodoro ◽  
Vanderly Janeiro ◽  
Margareth Udo ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Cutaneous Leishmaniasis ◽  
Clinical Evaluation ◽  
Logistic Regression Analysis ◽  
Immunofluorescence Assay ◽  
American Cutaneous Leishmaniasis ◽  
Several Variables ◽  
Relationship Of ◽  
The Relationship

The purpose of this study was to investigate the relationship of several variables to the healing of lesions in patients with American cutaneous leishmaniasis (ACL). The patients with clinical and/or laboratorial diagnoses of the disease were followed up for varying periods after treatment by clinical evaluation and indirect immunofluorescence assay (IFA), from September 2000 to December 2003. The lesions of 85.3% of the 163 patients had healed by their last return for clinical evaluation, and of these, 82.7% had negative IFA results, indicating an association between the healing of lesions and IFA negativity (p=0.000). In patients evaluated up to 120 days after treatment, there was a significant association between negative IFA results and the healing of lesions (p=0.0000). Logistic regression analysis showed that negative IFA results on patients' first return after treatment predicted a 2.175 fold greater chance of lesion healing (p=0.0001). These results indicate an association between IFA negativity at the first return up to a period of 120 days, and the healing of lesions, and that the chances of healing are significantly higher in patients with negative IFA results at their first return after treatment.

Higher Plasma Aldosterone Concentrations Are Associated With Elevated Risk of Aortic Dissection and Aneurysm: a Case-Control Study

Hypertension ◽  
2022 ◽  
Author(s):  
Qing Zhu ◽  
Mulalibieke Heizhati ◽  
Mengyue Lin ◽  
Menghui Wang ◽  
Xiaoguang Yao ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Aortic Dissection ◽  
Logistic Regression Analysis ◽  
Primary Aldosteronism ◽  
Plasma Aldosterone ◽  
Control Group ◽  
Case Group ◽  
Relationship Of ◽  
The Relationship

Background: Animal models demonstrate circulating aldosterone leads to aortic dissection and aneurysm, whereas data from humans are lacking. Therefore, we aimed to examine the associations of plasma aldosterone concentrations (PAC) with aortic dissection and aneurysm. Methods: We identified patients with aortic dissection and aneurysm with assessed PAC before disease onset from hospital-based electronic database and set as case group. Simultaneously, age and gender-matched cohort with PAC measurement whereas without aortic dissection and aneurysm were selected as control group using ratio of 1:4. Multi-variable logistic regression analysis was used to assess the relationship of PAC with aortic dissection and aneurysm. Results: Totally, 133 cases and 531 controls (all hypertensive) were enrolled between 2004 and 2021, with 77.9% men, mean age of 55.5 years and PAC of 13.9 ng/dL. Case group showed significantly higher PAC(14.51 versus 13.65 ng/dL, P =0.012) than did control group. In logistic regression analysis, higher PAC exhibited 1.68-fold higher odds (95% CI, 1.14–2.48, P =0.008) for presence of aortic dissection and aneurysm, significant in adjusted model (odds ratio, 1.69 [95% CI, 1.11–2.57], P =0.015). In stratified analysis, the association between the 2 was observed in women of all ages and in men with coronary artery disease. Sensitivity analysis by excluding those under interfering agents at PAC measurement and those with primary aldosteronism did not change the relationship of the 2. Conclusions: Higher PAC is associated with the increased odd for aortic dissection and aneurysm in patients with hypertension, even in the absence of primary aldosteronism, implying that PAC might be a target for prevention.

scholarly journals Quality of life of elderly people who care for other elderly people with neurological diseases

2018 ◽  
Vol 21 (4) ◽  
pp. 428-438 ◽  
Author(s):  
Julimar Fernandes de Oliveira ◽  
Lais Lopes Delfino ◽  
Samila Sathler Taveres Batistoni ◽  
Anita Liberalesso Neri ◽  
Meire Cachioni
Keyword(s):  
Quality Of Life ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Elderly People ◽  
Logistic Regression Analysis ◽  
Neurological Diseases ◽  
The Elderly ◽  
Care Recipient ◽  
Categorical Variables

Abstract Objective: to investigate the relationships between the perceived quality of life of elderly people who care for other elderly people with neurological diseases (dementia and strokes) and the gender, age and caregiver burden, diagnosis, functional dependence, and cognitive status of the care recipient. Method: 75 caregivers aged over 60 years were interviewed using the Quality of Life Scale (CASP-19) and Zarit Burden Interview. The levels of physical vulnerability of the elderly were identified through the Lawton and Brody questionnaires and the Katz scale and the cognitive assessment of elderly care recipients was assessed with the Clinical Dementia Rating. The data were analyzed by chi-squared test (for comparison of categorical variables), Mann-Whitney and Kruskal-Wallis U tests (for comparison of continuous variables). To study the associations between variables, univariate logistic regression analysis was performed, followed by multivariate logistic regression analysis. Results: the age, gender of the caregiver, type of neurological condition, and physical and cognitive functioning of the care recipient did not statistically influence the quality of life of the caregiver. Elderly caregivers with higher levels of burden (≥29) were 11.4 times more likely to have a worse quality of life score (CI: 3.16-36.77; p <0.001). Conclusion: the quality of life of the elderly caregiver is negatively influenced by the burden involved in caring for another elderly person. Identifying the negative emotional aspects of caregivers that negatively affect their quality of life should be considered a target for intervention by health teams.

scholarly journals Chronic pain after breast surgery: incidence, associated factors, and impact on quality of life, an observational prospective study

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Gianluca Villa ◽  
Raffaele Mandarano ◽  
Caterina Scirè-Calabrisotto ◽  
Valeria Rizzelli ◽  
Martina Del Duca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Chronic Pain ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Breast Surgery ◽  
Factors Associated ◽  
Axillary Surgery

Abstract Background Chronic pain after breast surgery (CPBS) has a disabling impact on postoperative health status. Mainly because of the lack of a clear definition, inconsistency does exist in the literature concerning both the actual incidence and the risk factors associated to CPBS. The aim of this prospective, observational study is to describe the incidence of and risk factors for CPBS, according to the definition provided by the IASP taskforce. The impact of CPBS on patients’ function and quality of life is also described. Methods Women aged 18+ undergoing oncological or reconstructive breast surgery from Jan until Apr 2018 at the Breast Unit of Careggi Hospital (Florence, Italy) were prospectively observed. Postoperative pain was measured at 0 h, 3 h, 6 h, 12 h, 24 h, 48 h, and 3 months (CPBS) after surgery. Preoperative, intraoperative, and postoperative factors were compared in CPBS and No-CPBS groups through multivariate logistic regression analysis. Results Among the 307 patients considered in this study, the incidence of CPBS was 28% [95% CI 23.1–33.4%]. Results from the logistic regression analysis suggest that axillary surgery (OR [95% CI], 2.99 [1.13–7.87], p = 0.03), preoperative use of pain medications (OR [95% CI], 2.04 [1.20–3.46], p = 0.01), and higher dynamic NRS values at 6 h postoperatively (OR [95% CI], 1.28 [1.05–1.55], p = 0.01) were all independent predictors for CPBS. Conclusions Chronic pain after breast surgery is a frequent complication. In our cohort, long-term use of analgesics for pre-existing chronic pain, axillary surgery, and higher dynamic NRS values at 6 h postoperatively were all factors associated with increased risk of developing CPBS. The possibility to early detect persistent pain, particularly in those patients at high risk for CPBS, might help physicians to more effectively prevent pain chronicisation. Trial registration ClinicalTrials.gov registration NCT04309929.

scholarly journals Association of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse in Singapore

2005 ◽  
Vol 134 (2) ◽  
pp. 329-332 ◽  
Author(s):  
Y.-J. SUN ◽  
A. S. G. LEE ◽  
S.-Y. WONG ◽  
N. I. PATON
Keyword(s):  
Logistic Regression ◽  
Mycobacterium Tuberculosis ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Multivariate Logistic Regression Analysis ◽  
Beijing Genotype ◽  
Multivariate Logistic Regression ◽  
Tuberculosis Relapse ◽  
Relationship Of ◽  
The Relationship

The relationship of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse was examined. Beijing strains were detected from 32 out of 45 (71%) relapsed cases and 148 out of 290 (51%) non-relapsed cases. Multivariate logistic regression analysis revealed that Beijing genotype was significantly associated with tuberculosis relapse (OR 2·64, 95% CI 1·30–5·34, P=0·005).

scholarly journals Chronic pain after breast surgery: incidence, associated factors and impact on quality of life, an observational prospective study

2020 ◽  
Author(s):  
Gianluca Villa ◽  
Raffaele Mandarano ◽  
Caterina Scirè Calabrisotto ◽  
Valeria Rizzelli ◽  
Martina Del Duca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Chronic Pain ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Breast Surgery ◽  
Factors Associated ◽  
Axillary Surgery

Abstract Background. Chronic pain after breast surgery (CPBS) has a disabling impact on postoperative health status. Mainly because of the lack of a clear definition, inconsistency does exist in the literature concerning both the actual incidence and the risk factors associated to CPBS. The aim of this prospective, observational study is to describe the incidence of and risk factors for CPBS, according to the definition provided by the IASP taskforce. The impact of CPBS on patients’ function and quality of life is also described. Methods. Adult female patients scheduled for oncological or reconstructive breast surgery at the Breast Unit of Careggi Hospital (Florence, Italy) were prospectively observed. Postoperative pain was evaluated at 3 months (CPBS) after surgery. Preoperative, intraoperative, and postoperative factors were compared in CPBS and No-CPBS groups through multivariate logistic regression analysis. Results. Among the 307 patients considered in this study, the incidence of CPBS was 28% [95%CI 23.1%-33.4%]. Results from the logistic regression analysis suggest that axillary surgery (OR [95%CI], 2.99 [1.13-7.87], p=0.03), preoperative use of pain medications (OR [95%CI], 2.04 [1.20-3.46], p=0.01), and higher dynamic NRS values at 6 hours postoperatively (OR [95%CI], 1.28 [1.05-1.55], p=0.01) were all independent predictors for CPBS. Conclusions. Chronic pain after breast surgery is a frequent complication. In our cohort, long-term use of analgesics for preexisting chronic pain, axillary surgery, and higher dynamic NRS values at 6 hours postoperatively were all factors associated with increased risk of developing CPBS. The possibility to early detect persistent pain, particularly in those patients at high risk for CPBS, might help physicians to more effectively prevent pain chronicisation.Trial registration: clinicalTrials.gov registration NCT04309929

scholarly journals Chronic pain after breast surgery: incidence, associated factors and impact on quality of life, an observational prospective study

2021 ◽  
Author(s):  
Gianluca Villa ◽  
Raffaele Mandarano ◽  
Caterina Scirè Calabrisotto ◽  
Valeria Rizzelli ◽  
Martina Del Duca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Chronic Pain ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Breast Surgery ◽  
Factors Associated ◽  
Axillary Surgery

Abstract Background. Chronic pain after breast surgery (CPBS) has a disabling impact on postoperative health status. Mainly because of the lack of a clear definition, inconsistency does exist in the literature concerning both the actual incidence and the risk factors associated to CPBS. The aim of this prospective, observational study is to describe the incidence of and risk factors for CPBS, according to the definition provided by the IASP taskforce. The impact of CPBS on patients’ function and quality of life is also described. Methods. Women aged 18+ undergoing oncological or reconstructive breast surgery from Jan until Apr 2018 at the Breast Unit of Careggi Hospital (Florence, Italy) were prospectively observed. Postoperative pain was measured at 0hrs, 3hrs, 6hrs, 12hrs, 24hrs, 48hrs, and 3 months (CPBS) after surgery. Preoperative, intraoperative, and postoperative factors were compared in CPBS and No-CPBS groups through multivariate logistic regression analysis. Results. Among the 307 patients considered in this study, the incidence of CPBS was 28% [95%CI 23.1%-33.4%]. Results from the logistic regression analysis suggest that axillary surgery (OR [95%CI], 2.99 [1.13-7.87], p=0.03), preoperative use of pain medications (OR [95%CI], 2.04 [1.20-3.46], p=0.01), and higher dynamic NRS values at 6 hours postoperatively (OR [95%CI], 1.28 [1.05-1.55], p=0.01) were all independent predictors for CPBS. Conclusions. Chronic pain after breast surgery is a frequent complication. In our cohort, long-term use of analgesics for pre-existing chronic pain, axillary surgery, and higher dynamic NRS values at 6 hours postoperatively were all factors associated with increased risk of developing CPBS. The possibility to early detect persistent pain, particularly in those patients at high risk for CPBS, might help physicians to more effectively prevent pain chronicisation.Trial registration: clinicalTrials.gov registration NCT04309929

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