scholarly journals A case of chronic retinal necrosis after tube shunt surgery for secondary glaucoma associated with cytomegalovirus corneal endotheliitis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Katsue Imamachi ◽  
Aika Tsutsui ◽  
Kaoru Manabe ◽  
Masaki Tanito
Keyword(s):  
Visual Acuity ◽  
Secondary Glaucoma ◽  
Panretinal Photocoagulation ◽  
Shunt Surgery ◽  
Case Presentation ◽  
Retinal Lesion ◽  
Oral Valganciclovir ◽  
Tube Shunt ◽  
Better Than ◽  
Corneal Endotheliitis

Abstract Background We report a case of chronic retinal necrosis (CRN) combined with cytomegalovirus (CMV) corneal endotheliitis. Case presentation An 80-year old man was diagnosed with CRN that developed after tube shunt surgery with vitrectomy for secondary glaucoma associated with CMV corneal endotheliitis. After the use of oral valganciclovir and panretinal photocoagulation, the retinal lesion resolved rapidly and he has maintained visual acuity better than before the onset of CRN. Conclusions Use of oral valganciclovir, prophylactic panretinal photocoagulation for the non- perfusion area and vitrectomy were effective in maintaining the visual acuity for the patient with CRN.

Visual Loss

2013 ◽  
Author(s):  
Jess T. Whitson
Keyword(s):  
Visual Acuity ◽  
Visual Loss ◽  
Vision Loss ◽  
Neovascular Glaucoma ◽  
Shunt Surgery ◽  
Shunt Implantation ◽  
Shunt Group ◽  
Long Term Follow Up ◽  
Tube Shunt

Tube shunt surgery use has increased significantly in recent years. Once reserved as a treatment option for more refractory types of disease, such as uveitic or neovascular glaucoma, or for eyes that had failed one or more trabeculectomies, tube shunts are now being used by some surgeons in place of trabeculectomy as a first-line surgical alternative in eyes with other less aggressive or less difficult to control forms of glaucoma. Visual loss can occur following tube shunt implantation as a result of complications during the postoperative period or from the progression of underlying disease (see Table 40.1). Although tube shunt implantation is associated with similar postoperative complications as trabeculectomy surgery, such as hypotony, hemorrhage, and failure to control IOP, there are several unique complications that may develop with the use of tube shunts, many of which may result in vision loss. Visual loss following tube shunt surgery is not uncommon. A large, systematic literature review of tube shunts by Hong and coworkers reported rates of vision loss following tube shunt surgery (defined as loss of 2 or more lines of visual acuity at last follow-up) ranging from (mean [SD]) 24 (7)% with the Ahmed™ Glaucoma Valve (New World Medical, Inc., Rancho Cucamonga, California) to 33 (18)% with the Molteno® implant (Molteno Ophthalmic Ltd., Dunedin, New Zealand). In the Tube Versus Trabeculectomy (TVT) Study, an ongoing, prospective, randomized clinical trial that is comparing the Baerveldt® 350 mm tube shunt (Abbott Medical Optics, Inc., Santa Ana, California) to trabeculectomy with mitomycin-C (MMC) in eyes with previous trabeculectomy and/or cataract surgery, vision loss (defined as loss of 2 or more lines of Snellen visual acuity) occurred in 31 of the 107 patients (29%) in the tube shunt group. The occurrence of any postoperative complication significantly increased the risk of vision loss (p < 0.001), and this risk correlated to the number of complications. Corneal decompensation has been reported to occur in up to 30% of patients during long-term follow-up after tube shunt surgery.

scholarly journals Does ganciclovir exert retinal toxicity after multiple continuous intravitreal injections?

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Feng Hu ◽  
Ya Ma ◽  
Xiaoyan Peng
Keyword(s):  
Visual Acuity ◽  
Capillary Density ◽  
Acute Retinal Necrosis ◽  
Case Presentation ◽  
Visual Damage ◽  
Retinal Capillary ◽  
Single Flash ◽  
Interdigitation Zone ◽  
Anatomical Outcomes ◽  
Flash Response

Abstract Background The objective of this study is to report a case of acute retinal necrosis in which abnormalities in visual function did not correspond to retinal anatomical outcomes. Case presentation A 39-year-old female diagnosed with acute retinal necrosis underwent repeated (nine rounds) intravitreal ganciclovir injection (3 mg/0.1 ml) into the left eye, one injection every 2 weeks. During the therapy, the patient noticed her visual acuity declining gradually. The best corrected visual acuity in the left eye was 20/33. The visual field showed massive visual damage. There was no posterior necrotizing involvement, no macular edema or exudation, and only slight abnormity of the interdigitation zone in the fovea area was visible on OCT. Angio-OCT revealed normal capillary density of three retinal capillary and choriocapillaris layers. The visually evoked potential was normal. The photopic single-flash response showed a declined amplitude of a-wave and b-wave. The amplitudes of photopic 30 Hz flicker were decreased. Multifocal electroretinography revealed macular dysfunction. Conclusion Ganciclovir-associated photoreceptor damage may induce abnormalities in retinal function in response to multiple continuous intravitreal ganciclovir injections at a relatively high dosage (3 mg/0.1 ml).

scholarly journals Risk factors associated with progression of diabetic retinopathy in eyes treated with panretinal photocoagulation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sung Uk Baek ◽  
Min Seon Park ◽  
Bum-Joo Cho ◽  
In Won Park ◽  
Soonil Kwon
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Platelet Count ◽  
Multivariate Logistic Regression Analysis ◽  
Panretinal Photocoagulation ◽  
Lower Baseline ◽  
Uncontrolled Diabetes ◽  
High Platelet Count ◽  
Baseline Visual Acuity

AbstractUncontrolled diabetes has been associated with progression of diabetic retinopathy (DR) in several studies. Therefore, we aimed to investigate systemic and ophthalmic factors related to worsening of DR even after completion of panretinal photocoagulation (PRP). We retrospectively reviewed DR patients who had completed PRP in at least one eye with a 3-year follow-up. A total of 243 eyes of 243 subjects (mean age 52.6 ± 11.6 years) were enrolled. Among them, 52 patients (21.4%) showed progression of DR after PRP (progression group), and the other 191 (78.6%) patients had stable DR (non-progression group). The progression group had higher proportion of proliferative DR (P = 0.019); lower baseline visual acuity (P < 0.001); and higher platelet count (P = 0.048), hemoglobin (P = 0.044), and hematocrit, (P = 0.042) than the non-progression group. In the multivariate logistic regression analysis for progression of DR, baseline visual acuity (HR: 0.053, P < 0.001) and platelet count (HR: 1.215, P = 0.031) were identified as risk factors for progression. Consequently, we propose that patients with low visual acuity or high platelet count are more likely to have progressive DR despite PRP and require careful observation. Also, the evaluation of hemorheological factors including platelet counts before PRP can be considered useful in predicting the prognosis of DR.

scholarly journals Visual Outcomes of Macula-Involving Rhegmatogenous Retinal Detachment in Patients with and Without Age-Related Macular Degeneration

2022 ◽  
Author(s):  
P. Barrett Paulk ◽  
Dala Eloubeidi ◽  
John O. Mason III ◽  
Christine A. Curcio ◽  
Jason N. Crosson ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retinal Detachment ◽  
Macular Degeneration ◽  
Rhegmatogenous Retinal Detachment ◽  
Age Related Macular Degeneration ◽  
Light Perception ◽  
Postoperative Visual Acuity ◽  
Age Related ◽  
Functional Vision ◽  
Better Than

Abstract Background Patients presenting with macula-off rhegmatogenous retinal detachment (RRD) with concomitant age-related macular degeneration (AMD) and their treating physicians would benefit from knowledge regarding the visual prognosis after repair. The prognosis for such patients is not well known. The purpose of this study is to compare visual outcomes in macula-off RRD in eyes with AMD versus a group of comparison eyes without AMD. Methods This was a retrospective chart review of 1,149 patients. A total of 191 eyes met study criteria, 162 non-AMD eyes (controls) and 29 AMD eyes. The main outcome measure was postoperative visual acuity in control eyes versus AMD eyes, and this was compared using Fisher’s exact test. Results There was a statistically significant difference in postoperative visual acuity by AMD status, with those without AMD having a higher frequency of Count Fingers (CF), Hand Motion (HM), Light Perception (LP), or No Light Perception (NLP) vision (p = 0.023). More specifically 5.56% of non-AMD eyes and 3.45% of AMD eyes were 20/40 or better, 77.16% of non-AMD and 55.17% of AMD eyes were worse than 20/40 and better than 20/200, 10.49% of non-AMD eyes and 37.93% of AMD eyes were 20/200 or worse, and there were 11 eyes in the non-AMD group with CF, HM, LP, or NLP vision while there was only 1 eye in the AMD group with CF vision. Conclusions Though postoperative visual acuity was worse in the non-AMD group with a higher frequency of patients having final vision of CF, HM, LP, or NLP, this is not likely a clinically significant finding. Rather, it is a function of the difference in sample size and composition between the two groups. Importantly, this study suggests AMD patients can expect similar outcomes to non-AMD patients after RRD repair. Our study suggests that approximately 58% of patients with AMD can expect to maintain functional vision better than 20/200. We conclude that AMD patients can achieve functional vision after RRD surgery, similar to those without AMD. These findings may be helpful in guiding realistic expectations of AMD patients with RRD.

scholarly journals Epstein-Barr Virus-related Corneal Endotheliitis Accompanied with Secondary Glaucoma

2020 ◽  
Vol 61 (2) ◽  
pp. 205
Author(s):  
Yong Wun Cho ◽  
Hyun Ji Kang ◽  
Gyu Nam Kim ◽  
Hyun A Kim ◽  
In Young Chung ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Secondary Glaucoma ◽  
Barr Virus ◽  
Epstein Barr ◽  
Corneal Endotheliitis

scholarly journals Clinical differences between toric intraocular lens (IOL) and monofocal intraocular lens (IOL) implantation when myopia is determined as target refraction

2020 ◽  
Author(s):  
Da young Shin ◽  
Ho Sik Hwang ◽  
Hyun Seung Kim ◽  
Man Soo Kim ◽  
Eun Chul Kim
Keyword(s):  
Visual Acuity ◽  
Intraocular Lens ◽  
Corneal Astigmatism ◽  
Spherical Equivalent ◽  
Toric Intraocular Lens ◽  
Toric Iol ◽  
Iol Implantation ◽  
Monofocal Iol ◽  
Target Refraction ◽  
Better Than

Abstract Background: To analyze and compare the clinical results of toric intraocular lens (IOL) and monofocal IOL implantation when the target refraction value is determined -3 diopter (D) in cataract patients with corneal astigmatism >1.5 diopters (D).Methods: We performed a retrospective chart review for patients with corneal astigmatism >1.5D who underwent cataract surgery and their target refraction is determined -3D. 100 eyes (100 patients; monofocal IOL, 60; toric IOL, 40) were enrolled in the current study. Near and distant uncorrected visual acuity (UCVA), corrected VA, spherical equivalent and refractive, corneal astigmatism were evaluated before and after surgery.Results: The near UCVA of the toric IOL group (0.26±0.33) after cataract surgery was significantly better than that of the monofocal IOL group (0.48±0.32) (p=0.030). The distant UCVA of the toric IOL group (0.38 ± 0.14) was also significantly better than that of the monofocal IOL group (0.55 ± 0.22) (p = 0.026). There were no significant intergroup differences in postoperative best-corrected visual acuity (p = 0.710) and mean spherical equivalent (p = 0.465). In the toric IOL group, postoperative refractive astigmatism was -0.80 ± 0.46D and postoperative corneal astigmatism was -1.50 ± 0.62D, whereas the corresponding values in the monofocal IOL group were -1.65 ± 0.77D and -1.45 ± 0.64D; residual refractive astigmatism was significantly lower with toric IOL implantation compared with monofocal IOL implantation (p = 0.001). Conclusions: When myopic refraction such as -3D was determined as the target power in patients with corneal astigmatism, toric IOL implantation led to excellent improvement in both near and distant UCVA.

scholarly journals Effects of spectacles and telescopes on visual function in students with oculocutaneous albinism

2020 ◽  
Vol 20 (2) ◽  
pp. 758-767
Author(s):  
Siddeeqa Jhetam ◽  
Khathutshelo P Mashige
Keyword(s):  
Visual Acuity ◽  
Contrast Sensitivity ◽  
Reading Rate ◽  
Oculocutaneous Albinism ◽  
Eye Care ◽  
Significant Difference ◽  
Observational Study Design ◽  
The Mean ◽  
Better Than ◽  
Spectacle Correction

Purpose: To investigate the effects of spectacle and telescope corrections on visual acuity (VA), contrast sensitivity (CS) and reading rates (RR) in students with oculocutaneous albinism (OCA). Methods: An observational study design was conducted on 81 students with OCA. Distance and near VA, CS and RR were measured without correction, with spectacle correction and with a combination of spectacle correction and telescopes. Results: The mean distance and near VA values with a combination of spectacle correction and telescopes were significantly better than those without correction and with spectacle correction alone (p = 0.01). Mean CS values achieved with spectacles alone were significantly better than those obtained with a combination of spectacles and telescopes (p = 0.01). There was no significant difference between logCS values obtained without correction compared to those obtained with a combination of spectacle correction and telescopes. There were no significant differences between RR values obtained with a combination of spectacles and telescopes and those without and with spectacle correction alone (all p > 0.05). Conclusion: This article provides valuable information to eye care practitioners on the effects of spectacles and telescopes on visual acuity, contrast sensitivity and reading rate in students with OCA. Keywords: Oculocutaneous albinism; visual acuity; telescope; contrast sensitivity; reading rate.

Tube Shunt Related Complications of the Orbit

2013 ◽  
Author(s):  
Marc R. Criden
Keyword(s):  
Glaucoma Surgery ◽  
Shunt Surgery ◽  
Ocular Surgery ◽  
Significant Treatment ◽  
Mechanical Complications ◽  
Surface Areas ◽  
Eyelid Edema ◽  
Shunt Implantation ◽  
Orbital Complications ◽  
Tube Shunt

Orbital complications during or after glaucoma filtering or tube shunt surgery are relatively rare but may pose a significant treatment challenge or threat to vision. The incidence of complications is highly variable, and transient events may not be reported as frequently as those that persist. A variety of orbital complications occur following glaucoma surgery. Complications may be categorized as mechanical, infectious, neurogenic, or myogenic. However, each complication may be multimodal and fall into more than one category. Mechanical complications are the most frequent type of orbit complication related to glaucoma surgery and more specifically to tube shunt implantation. Mechanical complications include ptosis, lid retraction, strabismus, and proptosis. Several theories address why ptosis may occur after ocular surgery and why it may be either transient or permanent. The levator muscle may be damaged or dehisced by an eyelid speculum, leading to a lid droop. Bridle sutures, which are often used during glaucoma surgery, have also been implicated as they apply counter traction against the superior rectus muscle. Prolonged eyelid edema and local anesthesia have each been more strongly associated with postoperative ptosis. For more information on ptosis, see Chapter 25. Strabismus after tube shunt implantation is most commonly related to either the device itself or to scarring and fibrosis that develop postoperatively. Transient strabismus may be related to swelling or edema of local tissues and may also follow retrobulbar injection. The strabismus is usually incomitant and does not present with a characteristic pattern of deviation; thus, prisms and other nonsurgical treatments are seldom adequate. Although strabismus following tube shunt surgery is usually transient, persistent diplopia may occur. The type of implant, size, location, and material each play a role. Implants with larger surface areas have a higher incidence of motility disturbance due to mass effect. Tube shunt plates that require placement below the rectus muscles risk direct muscle injury or adhesion scarring to the implant. In addition, a pseudo-Brown’s syndrome may be created by a superonasal implant due to interference with the superior oblique muscle function. The bleb that develops around the tube shunt reservoir can also act as a mass.

Scleral Perforation

2013 ◽  
Author(s):  
Jorge L. Rivera-Velez
Keyword(s):  
Rare Complication ◽  
Scleral Buckling ◽  
Shunt Surgery ◽  
Santa Ana ◽  
Shunt Implantation ◽  
Increased Risk ◽  
Shunt Group ◽  
Risk Patients ◽  
Tube Versus ◽  
Tube Shunt

Scleral perforation during tube shunt implantation is a rare complication. In a recent publication of the Tube Versus Trabeculectomy Study, 3 out of 107 patients in the tube shunt group had scleral perforation during placement of a device. Merino-de-Palacios et al reported scleral perforation during tube shunt surgery in 1 of 86 eyes. The type of device used does not seem to be important in the incidence of scleral perforation. In the Tube Versus Trabeculectomy Study, Baerveldt® devices (Abbott Medical Optics, Inc., Santa Ana, California) were used exclusively, and Ahmed™ Glaucoma Valves (New World Medical, Inc., Rancho Cucamonga, California) and Molteno® implants (Molteno Ophthalmic, Ltd., Dunedin, New Zealand) were used in the study by Merino-de-Palacios et al. Serious sequelae, such as endophthalmitis or retinal detachment, have not been reported in recent literature following scleral perforation during tube shunt placement; nonetheless, this complication should be prevented and, if it does occur, managed promptly. Patients who are believed to have an increased risk for scleral perforation are myopic patients (>-6.00 D) and patients with previous extraocular muscle surgery. Patients with previous scleral buckle surgery, autoimmune diseases, scleritis, or any other conditions that cause or perpetuate thinning of the sclera potentially increase the risk. Patients with previous scleral buckling procedures who require tube shunt surgery will benefit from having the device anchored behind the buckle or directly over the buckle. No attempt should be made to dissect under the buckling device, as dissection may lead to the buckle anchoring sutures perforating the eye. The most common site for tube shunt implantation is the superotemporal quadrant, between the superior and lateral rectus muscles. This location offers the benefit of having the implant hidden under the superior eyelid, no oblique muscles in the region, and better intraoperative exposure, allowing the surgeon to place the implant farther from the limbus. The plate of the implant is usually attached to the sclera approximately 8–10 mm posterior to the limbus. This is also the thinnest portion of the sclera. Exposure when implanting the tube shunt is probably the most important factor in avoiding scleral perforation.

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