scholarly journals The role of oxytocin receptor gene (OXTR) DNA methylation (DNAm) in human social and emotional functioning: a systematic narrative review

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Catherine Maud ◽  
Joanne Ryan ◽  
Jennifer E. McIntosh ◽  
Craig A. Olsson
2022 ◽  
Vol 12 (1) ◽  
pp. 98
Author(s):  
Stefano Anzani ◽  
Loreta Cannito ◽  
Fabio Bellia ◽  
Alberto Di Domenico ◽  
Bernardo Dell’Osso ◽  
...  

Individual differences in temporal and probabilistic discounting are associated with a wide range of life outcomes in literature. Traditional approaches have focused on impulsiveness and cognitive control skills, on goal-oriented personality traits as well as on the psychological perception of time. More recently, literature started to consider the role of social and contextual factors in discounting behavior. Between others, higher generalized trust in human beings and specific trust in people who will deliver the future/probabilistic rewards have been related to a stronger willingness to wait and to assume risk. Moreover, the tendency to trust others has been associated with the oxytocin receptor gene regulation that can be modified by life experiences. In this perspective, we hypothesized that differences in the tendency to wait and to take risks for a more desirable reward according to the proposer’s trustworthiness could be related to a different level of DNA methylation at the oxytocin receptor gene. Findings confirmed that participants are less willing to wait and to risk when the proposer is considered highly untrustworthy and revealed how higher oxytocin receptor gene DNA methylation is associated with a stronger effect due to the presence of an untrustworthy proposer. Limits and future directions are outlined.


Author(s):  
Amanda Denes ◽  
Anuraj Dhillon ◽  
Ambyre L. P. Ponivas ◽  
Kara L. Winkler

Sexual communication is a pivotal part of interpersonal relationships; recent research reveals associations between sexual communication and various relational outcomes. Within the broad domain of sexual communication, current scholarship specifically addresses the role of postsex communication in relationships and its links to physiological and genetic markers. Given these advancements, the present chapter offers an overview of research linking physiology, hormones, and genes to communication after sexual activity. The chapter first presents reviews of two key hormones in sexual communication research: testosterone (T) and oxytocin (O). The oxytocin receptor gene and its link to social behavior broadly, and sexual behavior specifically, is also explored. The chapter then offers a review of several theories relevant to understanding the hormonal underpinnings of sexual communication, as well as future directions for research exploring sexual communication and physiology.


2019 ◽  
Vol 98 ◽  
pp. 104151 ◽  
Author(s):  
Ashley M. Ebbert ◽  
Frank J. Infurna ◽  
Suniya S. Luthar ◽  
Kathryn Lemery-Chalfant ◽  
William R. Corbin

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