scholarly journals Suicidal ideation, psychopathology and associated factors among HIV-infected adults in Indonesia

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Youdiil Ophinni ◽  
Adrian ◽  
Kristiana Siste ◽  
Martina Wiwie ◽  
Gina Anindyajati ◽  
...  

Abstract Background Suicidal behavior is a prevalent psychiatric emergency in HIV-infected adults. Detection of suicidal ideation is important in planning early psychiatric intervention and optimizing HIV/AIDS management. Characterization of suicidal ideation among HIV-infected adults is crucial; however, practically there is no data in Indonesia, the country with the second largest burden of HIV/AIDS epidemic in Asia. This study aims to identify suicidal ideation and analyze the associated psychopathology and determining factors among HIV-infected adults in Indonesia. Methods An observational cross-sectional study was conducted among HIV-infected adults aged 18–65 years old receiving antiretroviral therapy (ART). Measurement using Symptom Checklist-90 (SCL-90) was performed to assess the existing psychopathology. Firth’s penalized logistic regression analysis was performed to identify factors associated with suicidal ideation. Results A total of 86 subjects were recruited. Most subjects were male (65.1%), median age was 35 years, and median latest CD4 count was 463 cells/μl. Lifetime suicidal ideation was identified in 20 subjects (23.3%). Mean SCL-90 T-score for depressive and anxiety symptoms were both significantly higher among subjects with suicidal ideation (M = 60.75, SD = 12.0, p = 0.000 and M = 57.9, SD = 2.8, p = 0.001, respectively) compared to those without. Bivariate analyses showed that lifetime suicidal ideation was associated with depressive and anxiety symptoms, non-marital status, CD4 count < 500 cells/μl, and efavirenz use. Multivariate analysis identified that a single-point increase in SCL-90 depression symptoms score (AOR 1.16, 95% CI 4.5–123.6, p = 0.000) and efavirenz use (AOR 5.00, 95% CI 1.02–24.6, p = 0.048) were significant independent factors related to suicidal ideation. Conclusion Suicidal ideation is commonly found among Indonesian HIV-infected adults on ART. Depressive symptoms and efavirenz use are independent factors related to the presence of suicidal ideation. Thus, early screening of psychopathology as well as substitution of efavirenz with other ART regiment are recommended to prevent suicide and improve HIV/AIDS management outcome.

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Huluagresh Bitew ◽  
Gashaw Andargie ◽  
Agitu Tadesse ◽  
Amsalu Belete ◽  
Wubalem Fekadu ◽  
...  

Background. Suicide is a serious cause of mortality worldwide and is considered as a psychiatric emergency. Suicide is more frequent in peoples living with HIV/AIDS than in general population.Objective. To assess the proportion and determining factors of suicidal ideation and attempt among peoples living with HIV/AIDS in Ethiopia.Methods. Institutional based cross-sectional study was conducted from May to June 2015 by selecting 393 participants using systematic random sampling technique. Suicide manual of Composite International Diagnostic Interview (CIDI) was used to collect data. Logistic regression was carried out and odds ratio with 95% confidence intervals was computed.Results. The proportion of suicidal ideation and attempt was 33.6% and 20.1%, respectively. Female sex (AOR = 2.6, 95%CI: 1.27–5.22), marital status (AOR = 13.5, 95%CI: 4.69–39.13), depression (AOR = 17.0, 95%CI: 8.76–33.26), CD4 level (AOR = 2.57, 95%CI: 1.34–4.90), and presence of opportunistic infection (AOR = 5.23, 95%CI: 2.51–10.88) were associated with suicidal ideation, whereas marital status (AOR = 8.44, 95%CI: 3.117–22.84), perceived HIV stigma (AOR = 2.9, 95%CI: 1.45–5.99), opportunistic infection (AOR = 2.37, 95%CI: 1.18–4.76), and poor social support (AOR = 2.9, 95%CI: 1.58–5.41) were significantly associated with suicidal attempt.Conclusion. Suicidal ideation and attempt were high among HIV positive patients. Therefore early screening, treatment, and referral of suicidal patients are necessary in HIV clinics.


2010 ◽  
Vol 5 (1) ◽  
pp. 29-32
Author(s):  
L Shrestha ◽  
BK Subedi ◽  
A Subedi

HIV/AIDS epidemic has been gradually spreading in Nepal. It is one of the major public health problems of the nation. Treatment, Care and Support are the critical and essential components of the response to HIV infection and AIDS related morbidity in Nepal. The cross sectional study was carried out at four public and three private Anti Retroviral Therapy (ART) sites during last 6 months of 2006 by selecting public ART sites based on the developmental regions of the country. From institutional set-up, human resources supply and availability of ART medicine's perspectives, the management practices of ART in Nepal is satisfactory. However, services need to be improved to make it more effective and efficient and client friendly, considering the standardization and sustainability of services. Government has targeted to increase the number of certified service delivery points for provision of comprehensive treatment and care services in relation to HIV/AIDS. Hence, in order to achieve the targets with increasing the coverage there is a need to review the management process in established ART service delivery sites. Key Words: HIV/AIDS; Nepal; ART DOI: 10.3126/saarctb.v5i1.3081 SAARC J. Tuber. Lung Dis. HIV/AIDS 2008 Vol.5(1)


2020 ◽  
Vol 11 ◽  
pp. 215013272095368 ◽  
Author(s):  
Alexander Bäuerle ◽  
Jasmin Steinbach ◽  
Adam Schweda ◽  
Jil Beckord ◽  
Madeleine Hetkamp ◽  
...  

Introduction: COVID-19 is causing an enormous psychological burden for most people. This study aims to assess individual changes in mental health and health status before and after the COVID-19 outbreak, and to explore potential predictors of change. Methods: A cross-sectional study in Germany (n = 15 037) were conducted. Demographics, depression and anxiety symptoms (PHQ-2, GAD-2), distress (DT), and health status (EQ-5D-3L) were assessed. Additionally, all instruments used were adapted to measure the participants’ mental health and health status before the COVID-19 outbreak. COVID-19-related fear, trust in governmental actions to face COVID-19, and the subjective level of information about COVID-19 were examined. Results: Overall, the participants showed a significant increase in depression and anxiety symptoms, and distress, while health status deteriorated since the COVID-19 outbreak. Impairment in mental health was predicted by COVID-19-related fear. Pre-existing mental illness predicted an increase in depression symptoms and a deterioration in health status. Trust in governmental actions and the subjective level of information predicted less increase in psychological burden. Conclusions: Our data revealed that there have been changes in mental health and health status at an individual level since the outbreak of COVID-19. In order to maintain mental health, the observed predictors should be addressed.


PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192940 ◽  
Author(s):  
Wei Wang ◽  
Chenchang Xiao ◽  
Xing Yao ◽  
Yinmei Yang ◽  
Hong Yan ◽  
...  

2013 ◽  
Vol 2 (2) ◽  
pp. 23-27 ◽  
Author(s):  
Mohammed Shahed Jahan ◽  
Mushfiq Hassan Shaikh ◽  
Jahanara Begum ◽  
Tazdik G Chowdhury ◽  
Morshed Hasan

Aims:This was a cross-sectional study done in the City Dental College, Malibagh, Chowdhurypara. The objective of the study was to assess the level of knowledge about HIV/AIDS among the final year dental students during the period between April to June 2012. Materials and Method:Convenient sampling technique was used and a total of 77 final year dental students were included. A pretested questionnaire was used in English and information was gathered by face to face interview regarding demographic characteristics and HIV/AIDS related knowledge which contained; meaning of HIV/AIDS cause of HIV/AIDS, mode of transmission, risk group, preventive measure. Result:The data were analyzed by computer software SPSS version 17. The study showed that 23.4 percent of the respondents had poor knowledge on HIV/AIDS. About 18.1% know that AIDS can be transmitted if having sexual contact with HIV positive case. Moreover, 13.8% have knowledge about HIV contaminated blood transfusion, 15.1% have knowledge about HIV infected mother to child, 14.6 % know that HIV infection can cause by pricking an infected needle and 10.5% know that it can transmit through body fluids like blood; semen etc. 45.1% had knowledge about injury by infected surgical instrument. Conclusion:The study revealed that the relationship between the knowledge of HIV/AIDS among dental students and sex of the respondents is statistically significant. It is evident that even in the second decade of the AIDS epidemic, final year dental students continue to have a lack of proper knowledge about HIV/AIDS. Training Programme should be arranged on HIV/AIDS for the dental students during clinical attachment. DOI: http://dx.doi.org/10.3329/updcj.v2i2.15531 Update Dent. Coll. j: 2012; 2 (2): 23-27


2009 ◽  
Vol 48 (173) ◽  
Author(s):  
Bidhan Nidhi Paudel ◽  
SR Chaudhary ◽  
S Sharma ◽  
GP Dhunagana ◽  
P Paydel

INTRODUCTION:Due to unavailability of vaccine against HIV/AIDS, there are no ways other than relying on ART. We select group of late stage HIV/AIDS with CD4<50 so that opportunistic infections and outcome of patients in this late stage of severe immunosuppression after initiation of ART can be knownMETHODS:A cross sectional study was carried out in 53 HIV patients with CD4 count <50 cells/cu mm blood undergoing ART in Seti Zonal Hospital Dhangadi between December 2006 and May 2008 with objectives to explore the treatment outcome in this late stage of immunosuppression. Only those patients with CD4 count <50 were consecutively selected and recommended for various laboratory test on the basis of which ART regimen were prescribed.RESULTS:Among 53 patients, 42 (79.2%) were males and 11 (20.8%) were females, with predominant age group of 30-40 years (49.1%). Fever (71.7%), diarrhea (56.6%), pneumonia (52.8%), weight loss (52.8%) and oral thrush (33.9%) were found to be the major clinical presentation/Opportunistic infections. 19 (35.8%) patients showed normal activity throughout the treatment period with increase in CD4 count, 10 (19%) were recovered and transferred out. Only 1 (1.8%) showed decrease in CD4 count even after taking ART. Significant relationship was established between the intake of ART and increase in CD4 level (pair t = 7.88, p<0.05).CONCLUSIONS:ART service was found to be efficient enough to increase the CD4 count significantly after 6 months of therapy but the prevalence of OIs/clinical manifestations were sufficiently higher in this group of patients with low CD4 count.Keywords: antiretroviral therapy, cell count, fever, opportunistic infections 


2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Etsay Hailu Gebremariam ◽  
Mebratu Mitiku Reta ◽  
Zebiba Nasir ◽  
Fisseha Zewdu Amdie

Background. Human Immune Deficiency Virus (HIV/AIDS) continues to be an underrecognized risk for suicidal ideation, suicidal attempt, and completion of suicide. Suicidal ideation and attempt in HIV/AIDS is not only a predictor of future attempted suicide and completed suicide.Methods. An institution based cross-sectional study was conducted among HIV-positive patients attending HIV care at Zewditu Memorial Hospital. Systematic random sampling technique was used to recruit 423 participants from April to May 2014. Composite International Diagnostic Interview was used to collect data. Multivariable logistic regression was computed to assess factors associated with suicidal ideation and attempt.Result. Suicidal ideation and suicidal attempt were found to be 22.5% and 13.9%, respectively. WHO clinical stage of HIV, not being on HAART, depression, family history of suicidal attempt, and perceived stigma were associated with suicidal ideation. WHO clinical stage, being female, not being on HAART, use of substance, and depression were associated with suicidal attempt.Conclusion. Early diagnosis and treatment of opportunistic infections, depression, and early initiation of ART need to be encouraged in HIV-positive adults. Furthermore, counseling on substance use and its consequences and early identification of HIV-positive people with family history of suicidal ideation have to be considered.


2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Miyabi Uda ◽  
Motomu Hashimoto ◽  
Ryuji Uozumi ◽  
Mie Torii ◽  
Takao Fujii ◽  
...  

Abstract Background The management of anxiety and depression symptoms in rheumatoid arthritis (RA) patients is vital. Previous study findings on this topic are conflicting, and the topic remains to be thoroughly investigated. This study aimed to clarify the association of RA disease activity with anxiety and depression symptoms after controlling for physical disability, pain, and medication. Methods We conducted a cross-sectional study of RA patients from the XXX Rheumatoid Arthritis Management Alliance cohort. We assessed patients using the Disease Activity Score (DAS28), Health Assessment Questionnaire Disability Index (HAQ-DI), and Hospital Anxiety and Depression Scale (HADS). Anxiety and depression symptoms were defined by a HADS score ≥ 8. We analyzed the data using multivariable logistic regression analyses. Results Of 517 participants, 17.6% had anxiety symptoms and 27.7% had depression symptoms. The multivariable logistic regression analysis demonstrated that DAS28 was not independently associated with anxiety symptoms (odds ratio [OR] [95% confidence interval; CI] 0.93 [0.48–1.78]; p = 0.82) and depression symptoms (OR [95% CI] 1.45 [0.81–2.61]; p = 0.22). However, DAS28 patient global assessment (PtGA) severity was associated with anxiety symptoms (OR [95% CI] 1.15 [1.02–1.29]; p = 0.03) and depression symptoms (OR [95% CI] 1.21 [1.09–1.35]; p < 0.01). Additionally, HAQ-DI scores ≤ 0.5 were associated with anxiety symptoms (OR [95% CI] 3.51 [1.85–6.64]; p < 0.01) and depression symptoms (OR [95% CI] 2.65 [1.56–4.50]; p < 0.01). Patients using steroids were more likely to have depression than those not using steroids (OR [95% CI] 1.66 [1.03–2.67]; p = 0.04). Conclusions No association was found between RA disease activity and anxiety and depression symptoms in the multivariable logistic regression analysis. Patients with high PtGA scores or HAQ-DI scores ≤ 0.5 were more likely to experience anxiety and depression symptoms, irrespective of disease activity remission status. Rather than focusing solely on controlling disease activity, treatment should focus on improving or preserving physical function and the patient’s overall sense of well-being.


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