scholarly journals Characteristics and trends of childhood cancer in Pudong, China, 2002–2015

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Junqi Ji ◽  
Zheng Luo ◽  
Yichen Chen ◽  
Xiaoyun Xu ◽  
Xiaopan Li ◽  
...  

Abstract Background With the growing threat of cancer to children’s health, it is necessary to analyze characteristics and trends of childhood cancer to formulate better cancer prevention strategies. Methods Data on the 430 children with cancer during 2002–2015 were collected from the Pudong Cancer Registry, diagnosed with the International Classification of Diseases for Oncology and categorized according to the International Classification of Childhood Cancer. The incidence rate, trends over time, and survival of patients grouped by sex, age, and region were explored using the Kaplan-Meier, Cox regression, and Joinpoint Regression models. Results The crude childhood cancer incidence and world age-standardized incidence rate (ASR) were 115.1/1,000,000 and 116.3/1,000,000 person-years. The two most frequent cancers were leukemia (136/430, 31.63%, ASR, 37.8/1,000,000 person-years) and central nervous system (CNS) tumors (86/430, 20.00%, ASR, 22.9/1,000,000 person-years). Our findings indicate that the survival rate for children between 10 and 15 years of age was higher than that for 5–10; and the survival rate for children who had leukemia was higher than that of children with CNS tumors. However, the overall incidence of childhood cancer, and leukemia, CNS tumors remained relatively stable in Pudong between 2002 and 2015. Conclusions The incidence and survival rate for childhood cancer patients varied by age and cancer type. The overall trends of childhood cancer incidence remained relatively stable in Pudong from 2002 to 2015 even though socioeconomic development has been unprecedentedly fast in this region.

2018 ◽  
Vol 14 (1) ◽  
pp. 51 ◽  
Author(s):  
Jane Kelly Oliveira Friestino ◽  
Denisa Mendonça ◽  
Pedro Oliveira ◽  
Carla Maria Oliveira ◽  
Djalma De Carvalho Moreira Filho

Analizamos los patrones espaciales y las incidencias de cáncer en niños, niñas y adolescentes de 0 a 19 años de edad residentes en la ciudad de Campinas, al sureste de Brasil, diagnosticados entre 1996 y 2005. Se clasificaron los cánceres según los grupos de la tercera revisión de la International Classification of Childhood Cancer (ICCC-3). Se incluyeron los cuatro grupos más comunes: leucemias, linfomas, y las neoplasias del sistema nervioso central y de tejidos blandos. Se calcularon tasas de incidencia estandarizadas por edad utilizando la población mundial estándar. Se ajustó un modelo espacial de regresión jerárquica de Bayes (controlando por la heterogeneidad de los datos y la autocorrelación espacial), que asume que el número de casos sigue una distribución de Poisson. Se diagnosticó un total de 180 casos durante el periodo de estudio. La tasa de incidencia bruta para las edades 0-19 años fue de 54,2 por millón y la tasa de incidencia estandarizada por edad fue de 56,5 por millón. Si bien algunas regiones presentan tasas de incidencia más altas al considerar la heterogeneidad y la autocorrelación, no se observaron diferencias estadísticamente significativas en los riesgos relativos.


2019 ◽  
Vol 21 (Supplement_5) ◽  
pp. v1-v100 ◽  
Author(s):  
Quinn T Ostrom ◽  
Gino Cioffi ◽  
Haley Gittleman ◽  
Nirav Patil ◽  
Kristin Waite ◽  
...  

AbstractThe Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) tumors in the United States (US) and represents the entire US population. This report contains the most up-to-date population-based data on primary brain tumors available and supersedes all previous reports in terms of completeness and accuracy. All rates are age-adjusted using the 2000 US standard population and presented per 100,000 population. The average annual age-adjusted incidence rate (AAAIR) of all malignant and non-malignant brain and other CNS tumors was 23.41 (Malignant AAAIR = 7.08, non-Malignant AAAIR = 16.33). This rate was higher in females compared to males (25.84 versus 20.82), Whites compared to Blacks (23.50 versus 23.34), and non-Hispanics compared to Hispanics (23.84 versus 21.28). The most commonly occurring malignant brain and other CNS tumor was glioblastoma (14.6% of all tumors), and the most common non-malignant tumor was meningioma (37.6% of all tumors). Glioblastoma was more common in males, and meningioma was more common in females. In children and adolescents (age 0–19 years), the incidence rate of all primary brain and other CNS tumors was 6.06. An estimated 86,010 new cases of malignant and non-malignant brain and other CNS tumors are expected to be diagnosed in the US in 2019 (25,510 malignant and 60,490 non-malignant). There were 79,718 deaths attributed to malignant brain and other CNS tumors between 2012 and 2016. This represents an average annual mortality rate of 4.42. The five-year relative survival rate following diagnosis of a malignant brain and other CNS tumor was 35.8%, and the five-year relative survival rate following diagnosis of a non-malignant brain and other CNS tumors was 91.5%.


2013 ◽  
Vol 13 (4) ◽  
pp. 335-344
Author(s):  
Glaucia Perini Zouain-Figueiredo ◽  
Eliana Zandonade ◽  
Maria Helena Costa Amorim

OBJECTIVES: to analyze the patient characteristics and evaluate overall survival, survival according to demographic variables, the most common tumor groups and subgroups, the stages of disease, and risk factors after at least 5 years among children and adolescents with cancer who were admitted to a state referral hospital between 2000 and 2005. METHODS: the Kaplan-Meier method was employed to estimate survival. The survival curves were compared using the log-rank test. The Cox regression model was used to estimate the effect of independent variables. RESULTS: a total of 571 new cases were registered. The most frequent cancer groups were leukemia (34%), lymphoma (18%), and central nervous system (CNS) tumors (15%).The overall survival rate was 59%. The risk factors associated with lower survival were an age of more than 4 years or less than 1 year, the presence of CNS tumors, and non-localized disease. CONCLUSION: although this was not a populationbased study, it provides important epidemiological information about a state where population data on childhood and adolescent cancer are scarce and where hospital-based data do not exist. The survival rate found here should serve as a framework for future improvements, helping to guide policymakers focused on pediatric oncology in the state.


PEDIATRICS ◽  
1984 ◽  
Vol 74 (1) ◽  
pp. 160-161
Author(s):  
ARNALL PATZ

The new international classification of the acute retinopathy of prematurity appearing in this issue1 is a timely and important contribution to the ocular examination and management of the retinopathy in these premature infants. During the epidemic period of the retinopathy of prematurity, generally designated then as retrolental fibroplasia, the survival rate of very small premature infants with birth weight less than 1,000 g was less than 10%. By the 1980s, due to improved neonatal care, that survival rate has increased by fourfold or greater. These low-birth-weight infants, who are at the highest risk of developing the retinopathy of prematurity, are surviving today, but in the early 1950s they would not have lived long enough to develop the disease.


Cancer ◽  
2005 ◽  
Vol 103 (7) ◽  
pp. 1457-1467 ◽  
Author(s):  
Eva Steliarova-Foucher ◽  
Charles Stiller ◽  
Brigitte Lacour ◽  
Peter Kaatsch

2012 ◽  
Vol 32 (3) ◽  
pp. 131-139 ◽  
Author(s):  
D. Mitra ◽  
A.K. Shaw ◽  
K. Hutchings

Introduction Cancer is the leading cause of disease-related death in children aged 1 to 14 years in Canada. Despite the importance to public health of childhood cancer, there have been few reports on Canadian trends published in the peer-reviewed literature. This study examines childhood cancer trends by age, sex, and province of residence using the most current cancer registration data. Methods Data from the population-based Canadian Cancer Registry were used to compute incidence trends in primary cancers diagnosed between 1992 and 2006 in children (0-14 years) for the 12 major diagnostic groups of the International Classification of Childhood Cancer, 3rd edition. Results Between 1992 and 2006, incidence rates for all cancers remained stable, although trends varied by cancer type. We observed a significant decrease in retinoblastoma in boys for the entire period (−6.5% per year) and an increase in leukemia from 1992 to 1999 (+3.5% per year). In girls, there was a significant decrease in renal tumours from 1998 to 2006 (−5.7% per year) and an increase in hepatic tumours from 1997 to 2006 (+8.1% per year). Differences by age and province were also apparent. Some caution should be exercised when interpreting trends involving a small number of cases per year and those with wide 95% confidence intervals. Conclusion Our findings suggest an ongoing need for population-based surveillance and etiologic research.


2020 ◽  
Vol 51 (4) ◽  
pp. 914-938
Author(s):  
Anna Cronin ◽  
Sharynne McLeod ◽  
Sarah Verdon

Purpose Children with a cleft palate (± cleft lip; CP±L) can have difficulties communicating and participating in daily life, yet speech-language pathologists typically focus on speech production during routine assessments. The International Classification of Functioning, Disability and Health: Children and Youth Version (ICF-CY; World Health Organization, 2007 ) provides a framework for holistic assessment. This tutorial describes holistic assessment of children with CP±L illustrated by data collected from a nonclinical sample of seven 2- to 3-year-old children, 13 parents, and 12 significant others (e.g., educators and grandparents). Method Data were collected during visits to participants' homes and early childhood education and care centers. Assessment tools applicable to domains of the ICF-CY were used to collect and analyze data. Child participants' Body Functions including speech, language, and cognitive development were assessed using screening and standardized assessments. Participants' Body Structures were assessed via oral motor examination, case history questionnaires, and observation. Participants' Activities and Participation as well as Environmental and Personal Factors were examined through case history questionnaires, interviews with significant others, parent report measures, and observations. Results Valuable insights can be gained from undertaking holistic speech-language pathology assessments with children with CP±L. Using multiple tools allowed for triangulation of data and privileging different viewpoints, to better understand the children and their contexts. Several children demonstrated speech error patterns outside of what are considered cleft speech characteristics, which underscores the importance of a broader assessment. Conclusion Speech-language pathologists can consider incorporating evaluation of all components and contextual factors of the ICF-CY when assessing and working with young children with CP±L to inform intervention and management practices.


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