Trend analysis of cardiovascular disease mortality, incidence, and mortality-to-incidence ratio: results from global burden of disease study 2017

Abstract Background Cardiovascular diseases (CVDs) are one of the global leading causes of concern due to the rising prevalence and consequence of mortality and disability with a heavy economic burden. The objective of the current study was to analyze the trend in CVD incidence, mortality, and mortality-to-incidence ratio (MIR) across the world over 28 years. Methods The age-standardized CVD mortality and incidence rates were retrieved from the Global Burden of Disease (GBD) Study 2017 for both genders and different world super regions with available data every year during the period 1990–2017. Additionally, the Human Development Index was sourced from the United Nations Development Programme (UNDP) database for all countries at the same time interval. The marginal modeling approach was implemented to evaluate the mean trend of CVD incidence, mortality, and MIR for 195 countries and separately for developing and developed countries and also clarify the relationship between the indices and Human Development Index (HDI) from 1990 to 2017. Results The obtained estimates identified that the global mean trend of CVD incidence had an ascending trend until 1996 followed by a descending trend after this year. Nearly all of the countries experienced a significant declining mortality trend from 1990 to 2017. Likewise, the global mean MIR rate had a significant trivial decrement trend with a gentle slope of 0.004 over the time interval. As such, the reduction in incidence and mortality rates for developed countries was significantly faster than developing counterparts in the period 1990–2017 (p < 0.05). Nevertheless, the developing nations had a more rather shallow decrease in MIR compared to developed ones. Conclusions Generally, the findings of this study revealed that there was an overall downward trend in CVD incidence and mortality rates, while the survival rate of CVD patients was rather stable. These results send a satisfactory message that global effort for controlling the CVD burden was quite successful. Nonetheless, there is an urgent need for more efforts to improve the survival rate of patients and lower the burden of this disease in some areas with an increasing trend of either incidence or mortality.

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Relation Between Lung Cancer Incidence and Mortality Rates with Human Development Index and Its Components: A Global Ecological Study

Iranian Journal of Cancer Prevention ◽

10.17795/ijcp-5310 ◽

2016 ◽

Vol In Press (In Press) ◽

Cited By ~ 2

Author(s):

Mokhtar Soheylizad ◽

Salman Khazaei ◽

Somayeh Khazaei ◽

Shahab Rezaeian

Keyword(s):

Lung Cancer ◽

Human Development ◽

Cancer Incidence ◽

Human Development Index ◽

Ecological Study ◽

Mortality Rates ◽

Lung Cancer Incidence ◽

Development Index ◽

Incidence And Mortality

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Global incidence and mortality rates in pancreatic cancer and the association with the Human Development Index: decomposition approach

Public Health ◽

10.1016/j.puhe.2017.12.015 ◽

2018 ◽

Vol 156 ◽

pp. 87-91 ◽

Cited By ~ 9

Author(s):

Y. Veisani ◽

E. Jenabi ◽

S. Khazaei ◽

Sh. Nematollahi

Keyword(s):

Pancreatic Cancer ◽

Human Development ◽

Human Development Index ◽

Mortality Rates ◽

Decomposition Approach ◽

Development Index ◽

Incidence And Mortality ◽

Index Decomposition

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689 THE HUMAN DEVELOPMENT INDEX IS ASSOCIATED WITH THE GLOBAL INCIDENCE AND MORTALITY RATES OF LIVER CANCER

Journal of Hepatology ◽

10.1016/s0168-8278(13)60691-1 ◽

2013 ◽

Vol 58 ◽

pp. S279-S280

Author(s):

Q.-D. Hu ◽

Q. Zhang ◽

W. Chen ◽

T.-B. Liang

Keyword(s):

Liver Cancer ◽

Human Development ◽

Human Development Index ◽

Mortality Rates ◽

Development Index ◽

Incidence And Mortality

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The incidence and mortality of cancer in Eastern Mediterranean Regional Office (EMRO) and its relationship with Human Development Index (HDI): An Ecological Study

Asian Pacific Journal of Environment and Cancer ◽

10.31557/apjec.2018.1.1.59-67 ◽

2018 ◽

Vol 1 (1) ◽

pp. 59-67

Author(s):

Zaher Khazaei ◽

Mojgan Navabi ◽

Isan Darvishi ◽

Elham Goodarzi

Keyword(s):

Human Development ◽

Human Development Index ◽

Mediterranean Region ◽

Eastern Mediterranean ◽

Developed Countries ◽

East Mediterranean ◽

Regional Office ◽

Development Index ◽

Incidence And Mortality ◽

East Mediterranean Region

Background: the cancer was considered as the second cause of mortality in the developed countries and all around the world after the cardiovascular diseases. Also, it was reported as the third cause of mortality in the less developed countries after cardiovascular diseases. The current study was aimed to evaluate the epidemiology, incidence, and mortality of all cancers in East-Mediterranean region by gender and age. Methods: This study was an ecologic study in Asia for assessment of the correlation between age-specific incidence rate (ASIR) and age-specific mortality rate (ASMR) with HDI (life expectancy at birth, mean years of schooling and gross national income (GNI) per capita) Data about SIR and SMR for every Asian country for the year 2012 were obtained from the global cancer project. Correlation bivariate method for assessment of the correlation between incidence and mortality rates was used. Statistical analysis using Stata-14 and P 05/0, respectively and a significant <0.05. Results: in East-Mediterranean region, some 555318 cases of cancer recorded in 2012. The highest incidence rates of cancer were reported for breast, colo-rectum, lung, liver, and bladder being 17.9%, 5.9%, 5.9%, 5.3%, and 5%, respectively. Also, the highest mortality of cancer were reported for breast, colo-rectum, lung, liver, and bladder being 11.5%, 5.8%, 5.9%, 7.6%, and 3.8%, respectively. The highest and lowest mortality ratios were reported for Somalia, and Saudi Arabia being 106.2, and 53.9 cases per 100000 people, respectively. Lung cancer and Human Development Index (HDI) had significant correlation with each other (P> 0.05). Also, a significant correlation was seen between Human Development Index (HDI) and mortality rates of breast, colorectal, lung and liver cancer (P> 0.05). Conclusion: the cancer was considered as one of the main causes of mortality in the most countries of East-Mediterranean region. The breast and colorectal cancers were reported as the most common types of cancer in this region. As for the alarming trend and remarkable distribution of cancer to the disease load in East-Mediterranean countries, controlling the cancer should be considered as one of the priorities of health policy. Key words: Cancer, Incidence, Mortality, Eastern Mediterranean Regional Office (EMRO).

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Variations in the Incidence and Mortality of Ovarian Cancer and Their Relationship with the Human Development Index in European Countries in 2012

Biomedical Research and Therapy ◽

10.15419/bmrat.v4i08.228 ◽

2017 ◽

Vol 4 (08) ◽

pp. 1541 ◽

Cited By ~ 1

Author(s):

Mahdi Mohammadian ◽

Mahin Ghafari ◽

Bahman Khosravi ◽

Hamid Salehiniya ◽

Mohammad Aryaie ◽

...

Keyword(s):

Ovarian Cancer ◽

Human Development ◽

Human Development Index ◽

National Income ◽

Mortality Rates ◽

European Countries ◽

Development Index ◽

Life Expectancy At Birth ◽

Bivariate Correlation ◽

Incidence And Mortality

Background: Ovarian cancer (OC) has high incidence and mortality rates among the reproductive system cancers. This study investigated the relationship between the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of OC and Human Development Index (HDI) in European countries in 2012. Methods: This ecological study assessed the correlation between the ASIR and ASMR of OC and HDI and its components including life expectancy at birth, average years of schooling, and gross national income (GNI) per capita. Bivariate correlation analysis was used for assessing the correlation between the ASIR and ASMR of OC and HDI and its components. All reported P values were two-sided. Statistical analyses were performed using SPSS (Version 15.0, SPSS Inc.). Results: The maximum ASIR of OC was observed in Latvia, Bulgaria, and Poland. The highest ASMR of OC was observed in Latvia, Lithuania, and Poland. The incidence and mortality rates of OC are expected to increase between 2012 and 2035. This increase will be more pronounced in women ≥ 65 years. HDI had a weak negative correlation with the ASIR of OC (r=- 0.213; P=0.186) and a weak positive correlation with the ASMR of OC (r=0.072; P=0.659). Conclusion: According to the results of this study, health policy makers must make appropriate decisions to deal with the increasing morbidity and mortality of OC, especially in women over 65 years of age, in regions with lower access to prevention and treatment services.

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Global Incidence and Mortality Rates of Stomach Cancer and the Human Development Index: an Ecological Study

Asian Pacific Journal of Cancer Prevention ◽

10.7314/apjcp.2016.17.4.1701 ◽

2016 ◽

Vol 17 (4) ◽

pp. 1701-1704 ◽

Cited By ~ 14

Author(s):

Salman Khazaei ◽

Shahab Rezaeian ◽

Mokhtar Soheylizad ◽

Somayeh Khazaei ◽

Azam Biderafsh

Keyword(s):

Human Development ◽

Stomach Cancer ◽

Human Development Index ◽

Ecological Study ◽

Mortality Rates ◽

Development Index ◽

Incidence And Mortality

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Abstract P1-09-06: Breast cancer in the Pan-American region: Inequities in incidence and mortality rates according to the human development index

10.1158/0008-5472.sabcs13-p1-09-06 ◽

2013 ◽

Cited By ~ 1

Author(s):

CH Barrios ◽

G Werutsky ◽

J Martínez-Mesa

Keyword(s):

Breast Cancer ◽

Human Development ◽

Human Development Index ◽

Mortality Rates ◽

Development Index ◽

Incidence And Mortality ◽

Pan American ◽

Pan American Region ◽

American Region

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Incidence and mortality of kidney cancer and its relationship with HDI (Human Development Index) in the world in 2012

Medicine and Pharmacy Reports ◽

10.15386/cjmed-691 ◽

2017 ◽

Vol 90 (3) ◽

pp. 286-293 ◽

Cited By ~ 4

Author(s):

Maryam Mohammadian ◽

Reza Pakzad ◽

Farhad Towhidi ◽

Behnam Reza Makhsosi ◽

Abbas Ahmadi ◽

...

Keyword(s):

Mortality Rate ◽

Human Development ◽

Kidney Cancer ◽

Human Development Index ◽

Developed Countries ◽

World Health ◽

Development Index ◽

Positive Correlation ◽

Incidence And Mortality ◽

The World

Background and aims. Kidney cancer is among the cancers that have the highest growth rate in all age and racial groups in the world and is as the most deadly type of urinary tract cancer. Since awareness about this cancer incidence status and mortality is essential for better planning, this study aimed to investigate the incidence and mortality rate of kidney cancer and its relationship with the development index in the world in 2012.Method. This study was an ecological study conducted based on GLOBOCAN project of the World Health Organization (WHO) for the countries in the world. The correlation between Standardized Incidence Rates (SIRs) and Standardized Mortality Rates (SMRs) of kidney cancer with HDI and its components was assessed using SPSS18.Results. In total, 337,860 incidence cases (213,924 were men and 123,936 women) and 143,406 deaths (90,802 cases in men and 52,604 in women) of kidney cancer were recorded in 2012. A positive correlation of 0.731 was seen between SIR of kidney cancer and HDI (p≤0.001). Also, a negative correlation of 0.627was seen between SMR of kidney cancer and HDI (p≤0.001). Conclusion. The incidence and mortality rate of kidney cancer is higher in developed countries. A significant positive correlation has been seen between the standardized incidence and mortality rate of kidney cancer with the Human Development Index and its components. We need more studies to examine variation in incidence and mortality of kidney cancer and its related factors in the world.

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