scholarly journals Projections of disability-adjusted life years for major diseases due to a change in vegetable intake in 2017–2040 in Japan

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Shiori Tanaka ◽  
Daisuke Yoneoka ◽  
Aya Ishizuka ◽  
Peter Ueda ◽  
Keiji Nakamura ◽  
...  

Abstract Background Low vegetable intake is one of the key dietary risk factors known to be associated with a range of health problems, including cardiovascular diseases (CVDs), cancer, and diabetes and kidney diseases (DKDs). Using data from Japan’s National Health and Nutrition Surveys and the Global Burden of Diseases study in 2017, this study aimed to forecast the impact of change in vegetable intake on disability-adjusted life years (DALYs) between 2017 and 2040 for three diseases. Methods We generated a three-component model of cause-specific DALYs, including changes in major behavioural and metabolic risk predictors, the socio-demographic index and an autoregressive integrated moving average model to project future DALY rates for 2017–2040 using the data between 1990 and 2016. Data on Vegetable consumption and risk predictors, and DALY rate were obtained from Japan’s National Health and Nutrition Surveys and the Global Burden of Diseases Study in 2017. We also modelled three scenarios of better, moderate and worse cases to evaluate the impact of change in vegetable consumption on the DALY rates for three diseases (CVDs, cancer, and DKDs). Results Projected mean vegetable intake in the total population showed a decreasing trend through 2040 to 237.7 g/day. A significant difference between the reference scenario and the better case scenario was observed with un-overlapped 95% prediction intervals of DALY rates in females aged 20–49 years (− 8.0%) for CVDs, the total population for cancer (− 5.6%), and in males (− 8.2%) and females (− 13.7%) for DKDs. Conclusions Our analysis indicates that increased vegetable consumption would have a significant reduction in the burdens of CVDs, cancer and DKDs in Japan. By estimating the disease burden attributable to low vegetable intake under different scenarios of future vegetable consumption, our study can inform the design of targeted interventions for public health challenges.

2020 ◽  
Author(s):  
Shiori Tanaka ◽  
Daisuke Yoneoka ◽  
Aya Ishizuka ◽  
Peter Ueda ◽  
Keiji Nakamura ◽  
...  

Abstract Background: Low vegetable intake is one of the key dietary risk factors known to be associated with a range of health problems, including cardiovascular diseases (CVDs), cancer, and diabetes and kidney diseases (DKDs). Using data from Japan's National Health and Nutrition Surveys and the Global Burden of Diseases study in 2017, this study aimed to forecast the impact of change in vegetable intake on disability-adjusted life years (DALYs) between 2017 and 2040 for three diseases. Methods: We generated a three-component model of cause-specific DALYs, including changes in major behavioural and metabolic risk predictors, the socio-demographic index and an autoregressive integrated moving average model to project future DALY rates for 2017-2040 using the data between 1990 and 2016. Data on Vegetable consumption and risk predictors, and DALY rate were obtained from Japan’s National Health and Nutrition Surveys and the Global Burden of Diseases Study in 2017. We also modelled three scenarios of better, moderate and worse cases to evaluate the impact of change in vegetable consumption on the DALY rates for three diseases (CVDs, cancer, and DKDs). Results: Projected mean vegetable intake in the total population showed a decreasing trend through 2040 to 237.7g/day. A significant difference between the reference scenario and the better case scenario was observed with un-overlapped 95% prediction intervals of DALY rates in females aged 20-49 years (-8.0%) for CVDs, the total population for cancer (-5.6%), and in males (-8.2%) and females (-13.7%) for DKDs. Conclusions: Our analysis indicates that increased vegetable consumption would have a significant reduction in the burdens of CVDs, cancer and DKDs in Japan. By estimating the disease burden attributable to low vegetable intake under different scenarios of future vegetable consumption, our study can inform the design of targeted interventions for public health challenges.


Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Shahab Khatibzadeh ◽  
Ashkan Afshin ◽  
Renata Micha ◽  
Peilin Shi ◽  
Mohammad Yawar Yakoob ◽  
...  

Background: Consumption of fruits and of vegetables each influence CVD risk. Yet, the global CVD mortality attributable to low intakes of each, by country, age, and sex, are not established. Objectives: To quantify the burdens of CVD attributable to low fruit consumption and low vegetable consumption by age and sex in 187 countries in 2010. Methods: We characterized consumption of fruits and vegetables by age, sex, and country based on 204 national and subnational surveys from 109 countries representing 85.2% of the world’s adult population complemented by bayesian hierarchical imputation for missing data. Etiologic effects of fruit and vegetable intake on CHD and stroke were quantified based on meta-analyses of prospective observational studies, supported by effects on CVD risk factors in intervention studies. Cause-specific mortality rates were obtained from the 2010 Global Burden of Diseases Study. CHD and stroke mortality attributable to low intakes of fruits [<300g/d] and vegetables (including legumes) [<400g/d] were estimated using comparative risk assessment, by country, age, and sex. Results: In 2010, 2,814,850 CVD deaths [95%UI: 2,652,230-2,977,471] were attributable to low fruit intake [36% CHD, 17% ischemic stroke, 47% hemorrhagic and other nonischemic stroke] and 1,922,582 CVD deaths [1,839,270-2,005,894] were attributable to low vegetable intake [42% CHD, 21% ischemic stroke, 37% hemorrhagic other nonischemic stroke]. Burdens were similar by sex: 55% and 54% of these deaths, respectively, occurred in men. Nearly 1 in 2 CVD deaths attributable to fruits and 2 in 5 attributable to vegetables occurred prematurely, before age 70 y. Substantial heterogeneity was evident across nations (Figure). Conclusions: These results highlight the substantial burdens as well as disparities in CVD attributable to insufficient consumption of fruits and vegetables around the world, informing prevention strategies and priorities.


2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Samuel Soledayo Babatola

Air pollution has remained a major issue of concern over the years with serious toxicological effects on human health. This paper evaluates the comparison of estimates and describes the global burden of diseases related to air pollution in the regions of WHO from 1990 to 2015. The study uses existing data from IHME on global burden of diseases (Mortality and Disability Adjusted Life Years) related to air pollution such as Trachea, Bronchus and Lung cancer, COPD, Ischemic heart disease and Stroke. This study shows that air pollution is one of the major environmental risk factors for the global burden of disease in 1990-2015 and has remained relatively stable for the past 25 years. By region, the largest burden of disease related to air pollution is found in Western Pacific and South-East Asia, reflecting the heavy industry and air pollution hotspots within the developing nations of these regions. Moreover, the rates of Disability Adjusted Life Years increased because of increase in pollution, especially in South-East Asia region, African region, and Eastern Mediterranean region where populations are both growing and ageing.


2017 ◽  
Vol 20 (suppl 1) ◽  
pp. 129-141 ◽  
Author(s):  
Paulo Andrade Lotufo ◽  
Alessandra Carvalho Goulart ◽  
Valéria Maria de Azeredo Passos ◽  
Fabio Mitsuhiro Satake ◽  
Maria de Fátima Marinho de Souza ◽  
...  

RESUMO: Objetivo: Verificar as tendências temporais das taxas de mortalidade, dos anos de vida perdidos (years of life lost - YLL) e dos anos de vida perdidos devido à incapacidade (years lost due to disability - YLD) motivadas pela doença cerebrovascular no Brasil entre 1990 e 2015. Métodos: Utilizou-se as informações do Global Burden of Diseases 2015 (GBD 2015) para analisar a magnitude e as tendências das taxas de mortalidade e dos anos de vida ajustados por incapacidade (DALY - disability-adjusted life years) nas 27 unidades da Federação, entre 1990 e 2015, pela doença cerebrovascular (CID-10: I-60-69). Os estados brasileiros foram analisados pelo índice de desenvolvimento social (IDS), composto por renda per capita, proporção de escolaridade formal aos 15 anos e taxa de fecundidade. Resultados: Apesar do aumento do número absoluto de mortes pela doença cerebrovascular, a proporção de mortes abaixo dos 70 anos de idade reduziu pela metade entre 1990 e 2015. A aceleração da queda foi maior entre as mulheres, e mais acentuada no período de 1990 e 2005 do que de 2005 a 2015. O risco de morte reduziu-se à metade em todo o país; porém, os estados no tercil inferior tiveram reduções menos expressivas para homens e mulheres (respectivamente, -1,23 e -1,84% ao ano), comparados aos no tercil médio (-1,94 e -2,22%) e no tercil superior (-2,85 e -2,82%). Os anos perdidos por incapacidade também apresentam redução entre os estados, mas de forma menos expressiva. Conclusão: Apesar da redução das taxas ajustadas por idade em todo o país, a doença cerebrovascular ainda apresenta alta carga de doença, principalmente nos estados com menor desenvolvimento socioeconômico.


2020 ◽  
pp. 095646242095298
Author(s):  
Augusto Cesar Lara de Sousa ◽  
Tatiana de Araujo Eleuterio ◽  
José Victor Afonso Coutinho ◽  
Raphael Mendonça Guimarães

To describe the trends of HIV/AIDS metrics related to the burden of disease for Brazil between 1990 and 2017 we conducted a timeseries analysis for HIV/AIDS indicators by extracting data from the Global Burden of Disease study. We calculated traditional prevalence, incidence and mortality rates, the number of years lost by HIV-related deaths (YLL) and disability (YLD), and disability-adjusted life years (DALY). We estimated time series models and assessed the impact of highly active antiretroviral therapy (HAART) on the same indicators. In the set of disability-adjusted life years (DALY), the highest weight of its magnitude was due to YLL. There was a decline, especially after 1996, of DALY, mortality and YLL for HIV/AIDS. However, YLD, incidence, and prevalence increased over the same period. Also, the analysis of interrupted time series showed that the introduction of HAART into health policy had a significant impact on indicators, especially for DALY and YLL. We need to assess the quality of life of people living with HIV, especially among older adults. In addition, we need to focus on primary prevention, emphasizing methods to avoid infection and public policies should reflect this.


2021 ◽  
Vol 31 (1) ◽  
Author(s):  
Deesha Deepak Ghorpade ◽  
Anchala Raghupathy ◽  
Jyoti Deepak Londhe ◽  
Sapna Jitendra Madas ◽  
Nisha Vijay Kale ◽  
...  

AbstractCOPD is the second leading cause of death and disability adjusted life years (DALYs) in India, yet, it remains poorly recognized. We aimed to study the level of awareness of COPD in urban slums of Pune city in India and its neighboring rural areas. All male and female subjects above the age of 30 years residing in 13 randomly selected slums of Pune city (total population of 3000) and 7 randomly selected neighboring rural villages (total population of 3000) were invited to participate in this cross-sectional community survey. After obtaining written informed consent, 13 trained community health workers (CHWs) administered a questionnaire that captured their level of awareness of COPD. Of the 6000 subjects approached, 5420 residents (mean age ± SD = 48.0 ± 13.5 years; 38% males) consented and answered all questions. The number of people who had ever heard the word COPD was 49/5420 [0.9% (0.6–1.1%); 0.7% (0.5–1.3%) of the urban slum dwellers and 1.15% (0.5–1.3%) of rural residents]. Among those who had never heard the word COPD (n = 5371), when asked what was the name of the disease caused by long-term tobacco smoking, 38% said cancer, 16.7% said asthma, and 4.4% said TB. Among those who had heard the word COPD (n = 49), 6.1% said it was a disease of the heart, and 61% attributed COPD to smoke and dust pollution and 20% to tobacco smoking. The level of awareness of COPD in the Indian community is extremely low, highlighting the need to have nationwide mass awareness programs in India.


2020 ◽  
Author(s):  
jefferson buendia ◽  
Fernando Polack ◽  
Juana Patricia Sanchez Villamil

Abstract BACKGROUND: Respiratory syncytial virus infection is the leading cause of bronchiolitis in Colombia. There is growing evidence about the impact of Respiratory syncytial virus on society in terms of years of life lost due to this condition. The objective of the present study is to determine the Disability-Adjusted Life Years for respiratory syncytial virus in children under 2 years in ColombiaMETHODS: Data from the national epidemiological surveillance system were used to estimate DALYs, calculated from the sum of years of life lost and years lived with disability due to RSV infection in Colombia. A bootstrapped method with 10000 iterations was used to estimate each statistical parameter using the package DALY calculator in R. RESULTS: In 2019, 260 873 years of life (CI95% 208 180- 347 023) were lost due to RSV bronchiolitis in Colombian children under 2 years. The estimated rate was 20 DALYs / 1000 person-year (95% CI 16 – 27).CONCLUSION: This is the first report estimating the impact of RSV bronchiolitis morbidity and mortality in Colombia. The findings of the present study suggest that the actual burden and cost of bronchiolitis due to RSV is high. Prevention strategies, such as RSV vaccination, to reduce morbidity associated with RSV infection should be encouraged in our country.


2021 ◽  
Vol 8 ◽  
Author(s):  
Jean Wilguens Lartigue ◽  
Olaoluwa Ezekiel Dada ◽  
Makinah Haq ◽  
Sarah Rapaport ◽  
Lorraine Arabang Sebopelo ◽  
...  

Background: Worldwide, neurological disorders are the leading cause of disability-adjusted life years lost and the second leading cause of death. Despite global health capacity-building efforts, each year, 22.6 million individuals worldwide require neurosurgeon's care due to diseases such as traumatic brain injury and hydrocephalus, and 13.8 million of these individuals require surgery. It is clear that neurosurgical care is indispensable in both national and international public health discussions. This study highlights the role neurosurgeons can play in supporting the global health agenda, national surgical plans, and health strengthening systems (HSS) interventions.Methods: Guided by a literature review, the authors discuss key topics such as the global burden of neurosurgical diseases, the current state of neurosurgical care around the world and the inherent benefits of strong neurosurgical capability for health systems.Results: Neurosurgical diseases make up an important part of the global burden of diseases. Many neurosurgeons possess the sustained passion, resilience, and leadership needed to advocate for improved neurosurgical care worldwide. Neurosurgical care has been linked to 14 of the 17 Sustainable Development Goals (SDGs), thus highlighting the tremendous impact neurosurgeons can have upon HSS initiatives.Conclusion: We recommend policymakers and global health actors to: (i) increase the involvement of neurosurgeons within the global health dialogue; (ii) involve neurosurgeons in the national surgical system strengthening process; (iii) integrate neurosurgical care within the global surgery movement; and (iv) promote the training and education of neurosurgeons, especially those residing in Low-and middle-income countries, in the field of global public health.


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