scholarly journals Health behaviors and metabolic risk factors are associated with dyslipidemia in ethnic Miao Chinese adults: the China multi-ethnic cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Fang Nie ◽  
Ziyun Wang ◽  
Qibing Zeng ◽  
Han Guan ◽  
Jingyuan Yang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Health Behaviors ◽  
Cardiovascular Risk Factors ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Metabolic Risk Factors ◽  
Lipoprotein Cholesterol ◽  
Metabolic Risk ◽  
Chinese Adults

Abstract Background Cardiovascular risk factors in Chinese ethnic minority groups are rarely reported. Objective To quantify the cardiovascular risk factors in Miao Chinese adults and to examine the association of health behaviors and metabolic risk factors with dyslipidemia. Methods A cross-sectional analysis was conducted using baseline data from the China Multi-Ethnic Cohort (CMEC) study. A representative sample of 5559 Miao participants aged 30 to 79 years were surveyed and given physical and laboratory exams. The proportion of behavioral and metabolic risk factors were described in ethnic Miao adults. Logistic regression was utilized to evaluate the odds ratio (OR) and 95% confidence interval (CI) of the association between health behaviors and metabolic risk factors with dyslipidemia. Results In Miao Chinese adults, the prevalence of dyslipidemia was 32.8%. After multivariate adjustment, subjects with poor waist-to-hip ratio (WHR), body mass index (BMI), fasting blood glucose (FBG) and blood pressure (BP) were more likely to have higher risk of triglycerides (TG) abnormality, regardless of gender and age. Furthermore, the strongly association was detected between poor WHR and low density lipoprotein cholesterol (LDL-C) abnormality (adjusted OR = 5.24, 95%CI: 2.42–11.34) in the older subgroup (≥ 60 years). Males who current smoking were an independent risk factor only for high density lipoprotein cholesterol (HDL-C) abnormality (adjusted OR = 1.44, 95%CI: 1.05–1.99). However, in the subgroup age, current smoker were at greater risk of high TG and low HDL-C. Males with regular drinking were less likely to be high LDL-C (adjusted OR = 0.51, 95%CI: 0.32–0.81). Conclusions The present findings indicated that Miao adults with metabolic risk factors were at greater risk of dyslipidemia.

scholarly journals Age at period cessation and trajectories of cardiovascular risk factors across mid and later life

Heart ◽  
2020 ◽  
Vol 106 (7) ◽  
pp. 499-505 ◽  
Author(s):  
Linda Marie O'Keeffe ◽  
Diana Kuh ◽  
Abigail Fraser ◽  
Laura D Howe ◽  
Debbie Lawlor ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Later Life ◽  
Glycated Haemoglobin ◽  
Lipoprotein Cholesterol ◽  
The Impact

ObjectiveTo examine the association between age at period cessation and trajectories of anthropometry, blood pressure, lipids and glycated haemoglobin (HbA1c) from midlife to age 69 years.MethodsWe used data from the UK Medical Research Council National Survey of Health and Development to examine the association between age at period cessation and trajectories of systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI) and waist circumference (WC) from 36 to 69 years and trajectories of triglyceride, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and HbA1c from 53 to 69 years.ResultsWe found no evidence that age at period cessation was associated with trajectories of log triglyceride, LDL-C and HDL-C from 53 to 69 years and trajectories of SBP or DBP from 36 to 69 years, regardless of whether period cessation occurred naturally or due to hysterectomy. While we found some evidence of associations of age at period cessation with log BMI, log WC and log HbA1c, patterns were not consistent and differences were small at age 69 years, with confidence intervals that spanned the null value.ConclusionHow and when women experience period cessation is unlikely to adversely affect conventional cardiovascular risk factors across mid and later life. Women and clinicians concerned about the impact of type and timing of period cessation on conventional cardiovascular intermediates from midlife should be reassured that the impact over the long term is small.

scholarly journals The Prevalence of Cardiovascular Risk Factors among Polish Soldiers: The Results from the MIL-SCORE Program

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Grzegorz Gielerak ◽  
Paweł Krzesiński ◽  
Katarzyna Piotrowicz ◽  
Piotr Murawski ◽  
Andrzej Skrobowski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Pressure Control ◽  
Cross Sectional Study ◽  
Lipoprotein Cholesterol ◽  
Risk Scores ◽  
Cross Sectional

The MIL-SCORE (Equalization of Accessibility to Cardiology Prophylaxis and Care for Professional Soldiers) program was designed to assess the prevalence and management of cardiovascular risk factors in a population of Polish soldiers. We aimed to describe the prevalence of cardiovascular risk factors in the MIL-SCORE population with respect to age. This observational cross-sectional study enrolled 6440 soldiers (97% male) who underwent a medical history, physical examination, and laboratory tests to assess cardiovascular risk. Almost half of the recruited soldiers were past or current smokers (46%). A sedentary lifestyle was reported in almost one-third of those over 40 years of age. The prevalence of hypertension in a subgroup over 50 years of age was almost 45%. However, the percentage of unsatisfactory blood pressure control was higher among soldiers below 40 years of age. The prevalence of overweight and obese soldiers increased with age and reached 58% and 27%, respectively, in those over 50 years of age. Total cholesterol was increased in over one-half of subjects, and the prevalence of abnormal low-density lipoprotein cholesterol was even higher (60%). Triglycerides were increased in 36% of soldiers, and low high-density lipoprotein cholesterol and hyperglycemia were reported in 13% and 16% of soldiers, respectively. In the >50 years of age subgroup, high and very high cardiovascular risk scores were observed in almost one-third of soldiers. The relative risk assessed in younger subgroups was moderate or high. The results from the MIL-SCORE program suggest that Polish soldiers have multiple cardiovascular risk factors and mirror trends seen in the general population. Preventive programs aimed at early cardiovascular risk assessment and modification are strongly needed in this population.

scholarly journals Evaluation of Anthropometric Indices for Metabolic Syndrome and their Association with Metabolic Risk Factors among Healthy Individuals in New Belgrade

2013 ◽  
Vol 30 (1) ◽  
pp. 21-30
Author(s):  
Veroslava Stanković ◽  
Svetlana Stojanović ◽  
Nađa Vasiljević
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Blood Glucose ◽  
Health Risk ◽  
Density Lipoprotein ◽  
Metabolic Risk Factors ◽  
Lipoprotein Cholesterol ◽  
Metabolic Risk ◽  
Anthropometric Indices

Summary People with metabolic syndrome (MetSy) are about twice as likely to develop cardiovascular disease and over four times as likely to develop type 2 diabetes compared to subjects without metabolic syndrome. Waist circumferences (WC) and body mass index (BMI) are useful screening tools for making the diagnosis. MetSy has increased the health risk in primary care. The aim of the study was to evaluate the anthropometric indices for MetSy and determine which of simple anthropometric measurements is most closely associated with metabolic risk factors. The research included 264 individuals, of which 132 men with mean age (±SD) of 44.73 ±9.37 years and 132 women with mean age (±SD) of 46.67±8.44 years. Antropometric indicators were measured using standard protocols, without shoes and outerwear. BMI was calculated as weight/height2(kg/m2) ratio, as recommended by the World Health Organization (WHO). Blood pressure measurements were obtained with the subject in a seated position by using a standard mercury sphygmomanometer. Blood samples were obtained after a minimum of 12-h fast; the metabolic parameters (high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, triglycerides, blood glucose) were analyzed by standard procedures. Analysis of the examinees’ medical records was also performed. Metabolic syndrome was diagnosed using the International Diabetes Federation (IDF) criteria. The analysis of the research results were performed using the Statistical Package for Social Science version 10.0 (SPSS 10.0 for Windows). The prevalence of the metabolic syndrome was 44.7% in men and 43.2% in women. Normal-weight subjects of both sexes were significantly younger and had significantly lower blood glucose, total cholesterol, LDL and triglycerides than overweight and obese subjects. Systolic and diastolic blood pressure values were significantly increased in parallel with increasing of BMI. For the whole sample, both anthropometric indices had significant associations with the other five components of MetSy. Waist circumference is a simple measure of adiposity most strongly associated with metabolic abnormalities. The results obtained in this study indicate that WC is a good indicator of health risk in women but not in men. Measurement of WC by BMI categories may indicate a person with an increased risk of development of chronic diseases.

Effects of nutrition education on cardio-metabolic outcomes: A randomised clinical trial

2019 ◽  
Vol 79 (4) ◽  
pp. 458-470
Author(s):  
Hildemar Dos Santos ◽  
W Lawrence Beeson ◽  
Gina Segovia-Siapco ◽  
Brenda Koranda ◽  
Tony Jehi
Keyword(s):  
Risk Factors ◽  
Clinical Trial ◽  
Health Education ◽  
Intervention Group ◽  
Density Lipoprotein ◽  
Randomised Clinical Trial ◽  
Metabolic Risk Factors ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Metabolic Risk

Objective: The aim of this study was to assess the effect of Full Plate Diet (FPD) on the primary prevention of cardio-metabolic risk factors. Design: Randomised clinical trial. Setting: Drayson Center, Loma Linda University, CA, USA. Methods: Forty individuals were randomly assigned to either an intervention group receiving the FPD health education for 10 weeks or to a control group not receiving this intervention. Comprehensive evaluations of clinical and anthropometric outcomes were conducted at baseline and at the end of intervention. To assess within-group changes and between-group differences, a general linear model was used. Results: Significant reductions in weight (−1.54 kg, 95% confidence interval [CI] −2.5, −.54) and total cholesterol (TC) (−11.7 mg/dL; 95% CI −21.4, −2) and non-significant reductions in means for low-density lipoprotein cholesterol (LDL-C) (−7.3 mg/dL, 95% CI −16, 1.5) and triglycerides (−18.7 mg/dL, 95% CI −46, 8.5) were observed in the intervention group after 10 weeks compared with baseline. These reductions were non-significantly higher in the intervention compared with the control group. There were no significant mean changes in systolic and diastolic blood pressure, high-density lipoprotein cholesterol (HDL-C) and haemoglobin A1c (A1c) in the intervention group after 10 weeks. Conclusion: A multi-component programme comprising 10 weeks of health education that emphasised the high intake of fibre failed to significantly reduce cardio-metabolic risk factors. It did show a downward trend in triglycerides, TC and body weight that may be of clinical importance suggesting that a future investigation with a longer intervention duration is needed.

scholarly journals Distribution of C-reactive Protein and Its Association with Cardiovascular Risk Factors in a Population-Based Sample of Chinese

2010 ◽  
Vol 28 (6) ◽  
pp. 333-342 ◽  
Author(s):  
Yanfang Zhao ◽  
Rui Wang ◽  
Xiuqiang Ma ◽  
Xiaoyan Yan ◽  
Zhansai Zhang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Population Based ◽  
Lipoprotein Cholesterol ◽  
Urban Region ◽  
C Reactive Protein ◽  
Reactive Protein

C-reactive protein (CRP) levels vary remarkably with ethnic status. Its distribution and correlates should be investigated across diverse populations, and these were limited in a representative Chinese population. We investigated 3133 participants aged 18–80 years in Shanghai, which were sampled using a randomized, stratified, multi-stage sampling method. The distribution of CRP was highly skewed toward a lower level. The median CRP was 0.55 mg/L (0.61 mg/L in males, 0.51 mg/L in females). Participants living in urban region had higher CRP levels than those in rural region (0.67 vs. 0.46 mg/L). CRP levels showed significant correlation with traditional cardiovascular risk factors, and it was most strongly correlated with body mass index. Multivariate logistic regression analyses indicated that elevated CRP (being in the top 15 percentile of CRP; CRP ≥ 2.09 mg/L) was significantly associated with obesity, hypertension, diabetes, low high-density lipoprotein cholesterol, high low-density lipoprotein cholesterol, high triglycerides and cardiovascular disease history. In conclusion, the distribution of CRP in adult Chinese was comparable with that of many other Asian populations but different from that of Western populations. Metabolic impairment was associated with elevated CRP, and CRP levels should be interpreted in conjunction with the lipid profile.

scholarly journals Endothelial-mediated coronary flow reserve in patients with mild thyroid hormone deficiency

2009 ◽  
Vol 161 (2) ◽  
pp. 323-329 ◽  
Author(s):  
Bernadette Biondi ◽  
Maurizio Galderisi ◽  
Loredana Pagano ◽  
Milena Sidiropulos ◽  
Melania Pulcrano ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Coronary Flow Reserve ◽  
Coronary Flow ◽  
Cold Pressor Test ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Flow Reserve ◽  
Endothelial Response

ContextAlthough coronary flow reserve (CFR) is reduced in patients with subclinical hypothyroidism (SHypo), the endothelial response of coronary vasomotion has never been explored in this clinical setting.ObjectiveTo investigate the endothelial response of coronary flow in young and middle-aged patients with SHypo, without associated cardiovascular risk factors compared with healthy control subjects.Patients and methodsThe study population consisted of 20 women (mean age 38.4+12.1 years) with newly diagnosed, untreated and persistent SHypo due to Hashimoto's thyroiditis. A total of 15 volunteers served as controls. Age, gender, body surface area, glucose, insulin levels, heart rate, systolic, diastolic, and mean blood pressure were similar in patients and controls. Body mass index was significantly higher in SHypo patients. Total cholesterol and low-density lipoprotein cholesterol, despite not significant, tended to be higher, and high-density lipoprotein cholesterol to be lower in SHypo. Coronary blood flow velocities were recorded in patients at rest and after the cold pressor test (CPT), a stimulus that can be considered totally endothelium-dependent. CFR was calculated as the ratio of hyperemic-to-resting diastolic peak velocities.ResultsCoronary diastolic peak velocities at rest did not differ between the two groups but were significantly lower after CPT in patients with SHypo, thereby resulting in a lower CFR. The difference remained significant after adjusting resting and CPT velocities for the respective mean blood pressures. TSH was inversely correlated with CFR in the pooled population.ConclusionPatients with SHypo without associated cardiovascular risk factors have a coronary endothelial dysfunction that appears in response to a physiological stimulus (the CPT).

scholarly journals Dietary diversity score and cardiovascular risk factors in Tehranian adults

2006 ◽  
Vol 9 (6) ◽  
pp. 728-736 ◽  
Author(s):  
Leila Azadbakht ◽  
Parvin Mirmiran ◽  
Ahmad Esmaillzadeh ◽  
Fereidoun Azizi
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Glucose Concentration ◽  
Dietary Diversity ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Lipoprotein Cholesterol ◽  
Sectional Study ◽  
Cross Sectional

AbstractAimTo evaluate the relationship between dietary diversity score (DDS) and cardiovascular risk factors in Tehranian adults.MethodsIn this population-based cross-sectional study, a representative sample of 581 subjects (295 males and 286 females) aged over 18 years, residents of Tehran, participated. Hypercholesterolaemia, hypertriglyceridaemia and low high-density lipoprotein cholesterol were defined according to the Adult Treatment Panel III guidelines of the National Cholesterol Education Program. Diabetes was defined as fasting plasma glucose concentration ≥ 126 mg dl−1or 2-h post challenge glucose concentration ≥ 200 mg dl−1. Hypertension was defined on the basis of the sixth report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Dietary diversity was defined according to the Diet Quality Index revised.ResultsMean (±standard deviation) DDS was 6.15 ± 1.02. The probability of having diabetes (odds ratio (OR) among quartiles: 1.45, 1.26, 1.11 and 1.00, respectively;Pfor trend = 0.04) and hypertriglyceridaemia (OR = 1.41, 1.23, 1.05 and 1.00, respectively;Pfor trend = 0.04) decreased with increasing quartile of the diversity score for whole grains. The probability of having obesity (OR among quartiles: 1.39, 1.06, 1.03 and 1.00, respectively;Pfor trend = 0.03), hypercholesterolaemia (OR = 1.46, 1.28, 1.11 and 1.00, respectively;Pfor trend = 0.03), hypertension (OR = 1.32, 1.17, 1.13 and 1.00, respectively;Pfor trend = 0.03) and high low-density lipoprotein cholesterol (LDL-C) (OR = 1.25, 1.12, 1.07 and 1.00, respectively;Pfor trend = 0.04) decreased with increasing quartile of the diversity score for vegetables. The probability of having hypercholesterolaemia, high LDL-C, hypertension and diabetes decreased with quartile of the DDS. But the probability of being obese increased with quartile of the DDS (Pfor trend = 0.03).ConclusionDDS was inversely associated with cardiovascular risk factors in this cross-sectional study. Increased diversity scores of diets, to increase the variety score for vegetables, may be emphasised in programmes attempting to bring about changes in lifestyle.

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