scholarly journals Risk factors for some tropical diseases in an African country

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
F.-M. E. Uzoka ◽  
C. Akwaowo ◽  
C. Nwafor-Okoli ◽  
V. Ekpin ◽  
C. Nwokoro ◽  
...  

Abstract Background Often, non-clinical risk factors could affect the predisposition of an individual to diseases. Understanding these factors and their impacts helps in disease prevention and control. This study identified risk factors for malaria, yellow fever, typhoid, chickenpox, measles, hepatitis B, and urinary tract infection in a population in an African country. Methods Our study was an observational, correlational, and quantitative one that explored relationships among risk variables and disease prevalence - without modifying or controlling the variables. Data for this study was obtained through random sampling of a population of patients and physicians in the eastern/southern, western, and northern parts of Nigeria in 2015–2016. A total of 2199 patient consultation forms were returned by 102 (out of 125) physicians, and considered useful for analysis. Demographic data of patients, physicians, and diagnosis outcomes were analysed descriptively through frequency distributions, aggregate analysis, and graphs. The influence of risk factors on the disease manifestations (diagnosis outcomes) was determined using regression analysis. Results Our results show that living in a tropical climate is by far a major risk factor associated with tropical diseases (malaria: t = 19.9, typhoid: t = − 3.2, chickenpox: t = − 6.5 and typhoid: t = 12.7). The risk for contracting infections is relative to specific diseases; for example, contact with chickenpox infected person poses a high risk of contracting the virus (t = 41.8), while poor personal hygiene predisposes people to high risk of urinary tract infection (t = 23.6). On the other hand, urbanization and homelessness pose very low risks of disposing the individual to the diseases under consideration, while low fluid intake, lack of voiding, and wearing non-cotton underwear predispose individuals to few diseases. Conclusion The risk factors identified in our study exert differential and discriminating influences in the causation, predisposition, and transmission of these disease studied. It is recommended that significant effort be devoted by governments in the tropics to the mitigation of these modifiable risk factors. The most important strategy to mitigate the occurrence of these risk factors will be improving the living conditions of people and the provision of social protection measures to reduce the occurrence and burden of these diseases.

2017 ◽  
Vol 45 (3) ◽  
pp. 134-137 ◽  
Author(s):  
Jannatul Ferdaus ◽  
Golam Moinuddin ◽  
Mohammad Tariqul Islam ◽  
Md Harun Or Rashid ◽  
Mahjabin Rahman Shawly ◽  
...  

Urinary Tract Infection (UTI) is the leading cause of death in children below five years of age in Bangladesh. Identification of modifiable risk factors of UTI may reduce the chances of the disease. This hospital based case-control study was conducted from January 2008 to December 2008 in Bangabandhu Sheikh Mujib Medical University, Dhaka to determine risk factors associated with UTI in preschool children. A group of 201 children with UTI on the basis of urgency and frequency in micturition & lower abdominal pain with or without fever were considered as case subjects under this study. Analysis was conducted comparing data from case group against a control group of 311 healthy children who were reported to have no fever and abdominal pain. Wiping (from back to front), circumcision status, nappy use, obstructive uropathy, neurogenic bladder, poor personal hygiene and constipation were found to be potential factors for UTI under logistic regression. Among them, nappy use was the main contributing factor and circumcision status and constipation were the second and third largest contributing factors for UTI. Age and sex had no statistically significant association.Bangladesh Med J. 2016 Sep; 45 (3): 134-137


2018 ◽  
Vol 1 (3) ◽  
pp. 26-38
Author(s):  
Abdulghani Mohamed Alsamarai ◽  
Shler Ali Khorshed

Background: Urinary tract infection is common with health impact in women and characterised by failure to treatment and recurrent episodes. Aim: This study was conducted to determine the risk factors for the development of urinary tract infection in diabetic and pregnant women in comparison to student female. Materials and methods: A prospective cross-sectional study conducted during the period from 1st of June 2015 to the end of January 2016. The population included in the study are 563 women, of them 425 were outpatients, and 138 were inpatients. Their age range between 18 and 80 years, with a mean age of 33.59±15.29 years. Urine samples collected and cultured on blood agar and MacConkey agar by spread plate technique. Bacterial colonies with different morphology were selected, purified and identified according to their biochemical characteristics using conventional standard methods. Results: In diabetic women, there were no significant difference in mean age and BMI values between culture positive and culture negative groups. However, pus cell mean scale was significantly higher [P=0.000] in women with urinary tract infection [1.76±1.25] than in those with negative culture [0.69±1.00]. In pregnant women, BMI mean value was significantly [P=0.013] lower in pregnant women with UTI [26.14] as compared to those without infection [26.99]. Pus cell scale mean value was significantly [P=0.000] higher in pregnant women with UTI [1.55] than women with negative UTI [0.85]. While there was no significant difference in mean age between UTI positive and negative pregnant women. In female student, there was a significant difference between UTI infected and non-infected in mean age [P=0.041] and pus cell scale [P=0.000]. However, BMI was not significantly different between infected and non-infected female student. Other risk factors association are variables in the 3 groups when analysed using X2, while AUC and OR show different trends of association between risk factors and UTI. Conclusion: BMI, pus cell scale, child number, delivery method, operation history and hospital setting were significantly associated with culture positivity in the 3 studied groups as determined by AUC. While OR confirmed association with pus sale scale in the 3 groups.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tanya Babich ◽  
Noa Eliakim-Raz ◽  
Adi Turjeman ◽  
Miquel Pujol ◽  
Jordi Carratalà ◽  
...  

AbstractHospital readmissions following severe infections are a major economic burden on the health care system and have a negative influence on patients' quality of life. Understanding the risk factors for readmission, particularly the extent to which they could be prevented, is of a great importance. In this study we evaluated potentially preventable risk factors for 60-day readmission in patients surviving hospitalization for complicated urinary tract infection (cUTI). This was a multinational, multicentre retrospective cohort study conducted in Europe and the Middle East. Our cohort included survivors of hospitalization due to cUTI during the years 2013–2014. The primary outcome was 60-day readmission following index hospitalization. Patient characteristics that could have influenced readmission: demographics, infection presentation and management, microbiological and clinical data; were collected via computerized medical records from infection onset up to 60 days after hospital discharge. Overall, 742 patients were included. The cohort median age was 68 years (interquartile range, (IQR) 55–80) and 43.3% (321/742) of patients were males. The all-cause 60-day readmission rate was 20.1% (149/742) and more than half were readmitted for infection [57.1%, (80/140)]. Recurrent cUTI was the most frequent cause for readmission [46.4% (65/140)]. Statistically significant risk factors associated with 60-day readmission in multivariable analysis were: older age (odds ratio (OR) 1.02 for an one-year increment, confidence interval (CI) 1.005–1.03), diabetes mellitus (OR 1.63, 95% CI 1.04–2.55), cancer (OR 1.7, 95% CI 1.05–2.77), previous urinary tract infection (UTI) in the last year (OR 1.8, 95% CI: 1.14–2.83), insertion of an indwelling bladder catheter (OR 1.62, 95% CI 1.07–2.45) and insertion of percutaneous nephrostomy (OR 3.68, 95% CI 1.67–8.13). In conclusion, patients surviving hospitalization for cUTI are frequently re-hospitalized, mostly for recurrent urinary infections associated with a medical condition that necessitated urinary interventions. Interventions to avoid re-admissions should target these patients.


2014 ◽  
Vol 27 (3) ◽  
pp. 364 ◽  
Author(s):  
Ana Bispo ◽  
Milene Fernandes ◽  
Cristina Toscano ◽  
Teresa Marques ◽  
Domingos Machado ◽  
...  

<strong>Introduction:</strong> Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients.<br /><strong>Material and Methods:</strong> This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections.<br /><strong>Results:</strong> A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p &lt; 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p &lt; 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the<br />most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions.<br /><strong>Discussion:</strong> Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated.<br /><strong>Conclusion:</strong> Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions.<br /><strong>Keywords:</strong> Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.


2004 ◽  
Vol 163 (4-5) ◽  
pp. 234-238 ◽  
Author(s):  
Els Bakker ◽  
Jan van Gool ◽  
Marc van Sprundel ◽  
Jean Claude van der Auwera ◽  
Jean-Jacques Wyndaele

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