scholarly journals Low frequency of HPV positivity in breast tumors among patients from south-central Poland

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Beata Biesaga ◽  
Anna Janecka-Widła ◽  
Marta Kołodziej-Rzepa ◽  
Anna Mucha-Małecka ◽  
Dorota Słonina ◽  
...  
Keyword(s):  
Nested Pcr ◽  
Low Frequency ◽  
Breast Tumors ◽  
Hpv Infection ◽  
Breast Cancers ◽  
Study Objective ◽  
Papilloma Virus ◽  
Central Poland ◽  
South Central ◽  
Hpv Prevalence

Abstract Background Some studies suggest that Human Papilloma Virus (HPV) infection is important factor in carcinogenesis of breast tumors. This study’ objective was to analyze HPV prevalence in breast cancers of patients from south-central Poland. Materials and methods The study was performed based on archival paraffin embebbed and formalin fixed blocks in the group of 383 patients with breast cancer. HPV prevalence and its genotype were assessed, respectively by: nested PCR (with two groups of primers: PGMY09/PGMY11 and GP5+/GP6+), quantitative PCR (qPCR). Tumors were classified as HPV positive in case of at least one positive result in nested PCR and positive results in genotyping procedure. For all HPV positive tissues P16 immunostaining was applied in order to confirm active viral infection. Results In the group of 383 breast cancers, HPV positivity was found in 17 samples (4.4%) in nested PCR. All these samples were subjected to HPV genotyping. This analysis revealed presence of HPV type 16 into two tumors (0.5%). In these two cancers, P16 overexpression was reported. Conclusion In breast tumors of patients from south-central Poland in Poland, HPV positivity is demonstrated in very low percentage of cases.

The prevalence of HPV infection in rectal cancer – Report from South – Central Poland (Cracow region)

2019 ◽  
Vol 215 (9) ◽  
pp. 152513 ◽  
Author(s):  
Beata Biesaga ◽  
Anna Janecka-Widła ◽  
Marta Kołodziej-Rzepa ◽  
Dorota Słonina ◽  
Zbigniew Darasz ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Hpv Infection ◽  
Central Poland ◽  
South Central

Prevalence of human papilloma virus (HPV) and type distribution of genotypes (6, 11, 16 and 18) among Egyptian women

2020 ◽  
Vol EJMM29 (4) ◽  
pp. 45-50
Author(s):  
Sahar A. Ibrahim ◽  
Shimaa A. Abdel-Salam ◽  
Mohamed I. Amer ◽  
Abeer A. El-Sayed ◽  
Rania A. Hassan
Keyword(s):  
Reproductive Tract ◽  
Hpv Infection ◽  
Dna Testing ◽  
Papilloma Virus ◽  
Type Distribution ◽  
Hpv Dna ◽  
Hpv Dna Testing ◽  
Hpv Prevalence ◽  
Egyptian Women ◽  
Polymerase Chain

Background: Human papillomavirus (HPV) is the most common viral infection of the reproductive tract and the causative agent of cervical cancer and genital warts. Objectives: to study prevalence of HPV infection and type distribution of genotypes (6, 11, 16 and 18) among Egyptian females. Methodology: 65 Egyptian women were subjected to conventional Pap cytology, HPV DNA testing by polymerase chain reaction (PCR) and genotyping by multiplex PCR for genotypes (6, 11, 16 and 18) during the period from May 2018 until October 2018. Results: The prevalence of HPV among participants was (23.1%). only 20% of HPV positive cases, were infected by single HPV genotype and 80% were co-infected by more than one genotype. Conclusion: These data expand the knowledge concerning HPV prevalence and type distribution in Egypt which may help to create a national HPV prevention program.

scholarly journals Prevalence and determinants of high risk human papilloma virus in Hyderabad, India

2018 ◽  
Vol 7 (3) ◽  
pp. 1012 ◽  
Author(s):  
Chandana V. ◽  
Rasheeda Begum Gaguturu
Keyword(s):  
Cervical Cancer ◽  
High Risk ◽  
Human Papilloma Virus ◽  
Age Groups ◽  
Hpv Infection ◽  
Papilloma Virus ◽  
Hpv Dna ◽  
Economic Class ◽  
South Central ◽  
One Year

Background: Cervical cancer is the most common cancer among india women and age standardized mortality rate are the highest in south central Asia. In the past decade an among aetiologic association between infection with high risk human papilloma virus and development of cervical cancer has been increased. The study was aimed at studying the prevalence and determinants of high risk human papilloma virus in these patients.Methods: This study was conducted for a period of one year to know the prevalence and determinants of high risk human papilloma virus in the patients attending gynaec out patient department. A total of 266 married women between 15-75 were randomly selected for the study.Results: There is high prevalence of HPV in low (43.3%)/mid (37.4%) socio economic class (17.6%). But the result was not statistically significant (p=0.149). higher prevalence of HPV was found in multiparas (39.4%) compared to multiparas (33.3%) which was not statistically significant (p=0.233). Husbands of 252 women were circumcised out of which 96 wives were positive for HPV DNA (38.1%). Among 14 women with no history of circumcision in their husband HPV DNA positive (28.6%). Correlation of cytology with HPV DNA among different age groups showed increasing prevalence with age but the result was not statistically significant (p=0.115). the result showed that age at marriage, higher the prevalence of HPV DNA. The result was statistically significant (p=0.017). with increasing state of education, the prevalence of HPV infection decreased, but the result was not statically significant (p=0.142).51.3% of women of who were not education were positive for HPV as against only 25% of graduates were HPV positive.Conclusions: Genital hygiene, genetic polymorphisms and other environmental cofactors among HPV DNA positive women, which prevent oncogenesis.

scholarly journals Characteristics of clinical manifestation of pointed condylomas in men practicing sex with men

2019 ◽  
Vol 20 (4) ◽  
pp. 17-23
Author(s):  
V. B. Stoyanov ◽  
T. B. Semenova ◽  
V. A. Molochkov ◽  
O. B. Zhukov ◽  
S. Yu. Fominykh
Keyword(s):  
Oral Mucosa ◽  
Clinical Manifestation ◽  
Hpv Infection ◽  
Study Objective ◽  
Papilloma Virus ◽  
Doctor Visit ◽  
Rapid Dissemination ◽  
Hpv Types ◽  
Sex With Men ◽  
Stable Pairs

The study objective is to investigate the characteristics of clinical manifestation of pointed condylomas (PCs) in men practicing sex with men (MSM).Materials and methods. Eight MSM were under observation: 2 stable pairs and 4 unrelated homosexuals. Among them, 5 were between the ages of 18 and 26, 3 – between 40 and 51. In every case, men complained of nodular rash in the area of external genitals or anus. A test was performed to determine the presence of human papilloma virus (HPV) of high (16, 18, 26, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68, 71, 82) and low (6, 11, 44) cancerogenic risk.Results. In 4 patients, PCs were previously removed by destructive therapy multiple times. Remission lasted from 1 to 9 months. At the first examination, PCs on the penis were observed in all 8 patients, and in 3 PCs were also observed in the perineal area; 3 patients had PCs on the oral mucosa along with anogenital PCs. PCs appeared in the period between 3 weeks and 1.5 months prior to doctor visit. A trend towards rapid dispersion and expansion and fusion of PCs was noted by all patients. Associations of 2 HPV types were observed in 2 patients, of 3 types – in 3 patients, of 4 types – in 2 patients. HPV types of both high and low oncogenic risk were detected, but urethra, mouth and anus materials always contained DNA markers for type 6 and 11 HPV.Conclusion. MSM have the highest risk of HPV infection. All forms of homosexual sex are risk factors for HPV infection. Multicentricity and variety of proliferative skin and mucosal lesions are characteristic of the infection caused by HPV in MSM. Even in the absence of complaints, it is necessary to examine oral mucosa, tonsils and throat to rule out possible infection (including asymptomatic forms of HPV). PCs in MSM have a tendency towards rapid dissemination and growth. Type 6 and 11 HPV absolutely dominate in PCs. Meanwhile, different types of HPV in urethral, oral and anal materials can be explained both by contamination and uneven affinity of different HPV types towards epithelial cells of derma and mucosa. 

scholarly journals Association of serum 25-hydroxyvitamin D with prevalence, incidence, and clearance of vaginal HPV infection in young women

2020 ◽  
Author(s):  
Mariam El-Zein ◽  
Farzin Khosrow-Khavar ◽  
Ann N Burchell ◽  
Pierre-Paul Tellier ◽  
Shaun Eintracht ◽  
...  
Keyword(s):  
Vitamin D ◽  
Proportional Hazards ◽  
Hpv Infection ◽  
Cox Proportional Hazards ◽  
Baseline Serum ◽  
Hpv Dna ◽  
Hydroxyvitamin D ◽  
Hpv Prevalence ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D

Abstract Background We assessed the association between serum 25-hydroxyvitamin D levels and genital human papillomavirus (HPV) prevalence, incidence, and clearance among female participants of the HITCH cohort study. Methods We genotyped HPV DNA in vaginal samples and quantified baseline serum 25-hydroxyvitamin D levels using Roche’s Linear Array and Total vitamin D assay, respectively. We used logistic and Cox proportional hazards models to respectively estimate adjusted odds ratios (OR) and hazards ratios (HR) with 95% confidence intervals (CI). Results There was no association between vitamin D levels (every 10ng/mL increase) at baseline and HPV prevalence (OR=0.88, CI:0.73-1.03) or incidence (HR=0.88, CI:0.73-1.06), but we observed a modest negative association with HPV clearance (HR=0.76, CI:0.60-0.96). Vitamin D levels <30ng/mL, compared to ≥30ng/mL, were not associated with HPV prevalence (OR=0.98, CI:0.57-1.69) or incidence (HR=0.87, CI:0.50-1.43), but were associated with a marginally significant increased clearance (OR=2.14, CI:0.99-4.64). We observed consistent results with restricted cubic spline modelling of vitamin D levels and clinically defined categories. HPV type-specific analyses accounting for multiple HPV infections per participant showed no association between vitamin D levels and all study outcomes. Conclusion This study provided no evidence of an association between low vitamin D levels and increased HPV prevalence, acquisition, or clearance.

Signs of predation in the Middle Jurassic of south-central Poland: evidence from echinoderm taphonomy

Lethaia ◽  
2007 ◽  
Vol 40 (2) ◽  
pp. 139-151 ◽  
Author(s):  
MICHAŁ ZATOŃ ◽  
LOÏC VILLIER ◽  
MARIUSZ A. SALAMON
Keyword(s):  
Middle Jurassic ◽  
Central Poland ◽  
South Central

HPV prevalence among healthy Italian male sexual partners of women with cervical HPV infection

2008 ◽  
Vol 80 (7) ◽  
pp. 1275-1281 ◽  
Author(s):  
Maria Benevolo ◽  
Marcella Mottolese ◽  
Ferdinando Marandino ◽  
Mariantonia Carosi ◽  
Maria Grazia Diodoro ◽  
...  
Keyword(s):  
Hpv Infection ◽  
Sexual Partners ◽  
Hpv Prevalence ◽  
Male Sexual Partners

scholarly journals Awareness and Knowledge about Human Papilloma Virus Infection among Students at Secondary Occupational Health School in China

2021 ◽  
Vol 18 (12) ◽  
pp. 6321
Author(s):  
Xin Wang ◽  
Taifeng Du ◽  
Xiaoling Shi ◽  
Kusheng Wu
Keyword(s):  
Occupational Health ◽  
Human Papilloma Virus ◽  
Healthcare Providers ◽  
Human Papilloma Virus Infection ◽  
First Grade ◽  
Hpv Infection ◽  
Cross Sectional Study ◽  
Causal Link ◽  
Cross Sectional ◽  
Papilloma Virus

Cervical cancer (CC) is one of the most common causes of cancer-related deaths worldwide. CC is mainly caused by human papilloma virus (HPV), which can be prevented by vaccination. We conducted a cross-sectional study in secondary occupational health school (SOHS) through a questionnaire aimed to assess the awareness and knowledge regarding HPV infection of students. A total of 2248 students participated in the survey, 45.3% of them had heard about CC, while only 21.9% of them had heard about HPV; and 74.2% had no idea of the causal link between HPV infection and CC. Most participants displayed poor awareness and knowledge about HPV infection. The results suggested that age, grade, major, academic performance, etc. were correlated with higher awareness of CC, HPV and HPV infection (p < 0.05). In multivariable logistic analysis, third-grade students had the most increased awareness of CC (OR = 17.13, 95%CI: [8.11, 36.15]), HPV (OR = 6.59, 95%CI: [4.16, 10.43]) and HPV vaccine (OR = 2.78, 95%CI: [1.78, 4.32]) when compared to first-grade. Awareness and knowledge regarding HPV infection were insufficient among students in SOHS. As the future healthcare providers, these results highlight the need to supplement targeted education to improve their awareness and knowledge of HPV and vaccination.

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