scholarly journals Pilates and dance to patients with breast cancer undergoing treatment: study protocol for a randomized clinical trial – MoveMama study

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Leonessa Boing ◽  
Tatiana do Bem Fretta ◽  
Melissa de Carvalho Souza Vieira ◽  
Gustavo Soares Pereira ◽  
Jéssica Moratelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Body Image ◽  
Side Effects ◽  
Sleep Quality ◽  
Control Group ◽  
Belly Dance ◽  
Belly Dancing

Abstract Background Breast cancer is a global public health issue. The side effects of the clinical treatment can decrease the quality of life of these women. Therefore, a healthy lifestyle is essential to minimize the physical and psychological side effects of treatment. Physical activity has several benefits for women with breast cancer, and Pilates solo and belly dancing can be an enjoyable type of physical activity for women with breast cancer undergoing clinical treatment. The purpose of this study is to provide a Pilates solo and a belly dance protocol (three times per week/16 weeks) for women undergoing breast cancer treatment and compare its effectiveness with that in the control group. Methods The participants will be allocated to either the intervention arm (Pilates solo or belly dance classes three times per week for 16 weeks) or a control group (receipt of a booklet on physical activity for patients with breast cancer and maintenance of habitual physical activity routine). The Pilates solo and belly dance classes will be divided into three stages: warmup and stretching, the main stage, and relaxation. Measurements of the study outcomes will take place at baseline; postintervention; and 6, 12, and 24 months after the end of the intervention (maintenance period). The data collection for both groups will occur with a paper questionnaire and tests covering general and clinical information. The primary outcome will be quality of life (EORT QLQ-C30 and EORT QLQ-BR23), and secondary outcomes will be physical aspects such as cardiorespiratory fitness (6-min walk test and cycle ergometer), lymphedema (sum of arm circumference), physical activity (IPAQ short version), disabilities of the arm (DASH), range of motion (goniometer test), muscular strength (dynamometer test) and flexibility (sit and reach test), and psychological aspects such as depressive symptoms (Beck Depression Inventory), body image (Body Image After Breast Cancer Questionnaire), self-esteem (Rosenberg), fatigue (FACT-F), pain (VAS), sexual function (FSFI), and sleep quality (Pittsburgh Sleep Quality Index). Discussion In view of the high prevalence of breast cancer among women, the implementation of a specific protocol of Pilates solo and belly dancing for patients with breast cancer is important, considering the necessity to improve their physical and psychological quality of life. Pilates solo and belly dancing are two types of physical activity that involve mental and physical concentration, music, upper limb movements, femininity, and social involvement. An intervention with these two physical activities could offer options of supportive care to women with breast cancer undergoing treatment, with the aim being to improve physical and psychological quality of life. Trial registration ClinicalTrials.gov, NCT03194997. Registration date 12 August 2017. Universal Trial Number (World Health Organization), U1111-1195-1623.

scholarly journals Pilates and dance to breast cancer patients undergoing treatment: study protocol for a randomized clinical trial – MoveMama study

2019 ◽  
Author(s):  
Leonessa Boing ◽  
Tatiana do Bem Fretta ◽  
Melissa de Carvalho Souza Vieira ◽  
Gustavo Soares Pereira ◽  
Jéssica Moratelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Body Image ◽  
Side Effects ◽  
Psychological Aspects ◽  
Control Group ◽  
Belly Dance ◽  
Breast Cancer Patients

Abstract Background: Breast cancer is a global public health issue and the side effects of the clinical treatment can decline the quality of life of these women. Therefore, a healthy lifestyle is essential to minimize the physical and psychological side effects of treatment. Physical activity has several benefits for breast cancer women and Pilates solo and belly dance can be an enjoyable type of physical activity for breast cancer women undergoing clinical treatment. The purpose of the study will be to provide a Pilates solo and a belly dance protocol (3x/16 weeks) for women undergoing breast cancer treatment and compare its effects with the control group. Methods: The participants will be allocated to either the intervention arm (Pilates solo or belly dance classes 3x/week for 16 weeks) or a control group (receipt of a booklet on physical activity for breast cancer patients and maintenance of habitual physical activity routine). The Pilates solo and belly dance classes will be divided into three stages: warm-up and stretching; the main stage and relaxation. Measurements of study outcomes will take place at baseline, post-intervention, 6-, 12- and 24-months (maintenance period). The data collection for both groups will occur with a questionnaire application and tests, covering general and clinical information, primary outcome will be quality of life (EORT QLQ C30 and BR23), secondary outcomes will be physical aspects as cardiorespiratory fitness (6-minute walk test and cycle ergometer), lymphedema (sum of arm circumference), physical activity (IPAQ short version), disabilities of the arm (DASH), range of motion (goniometer test), strength (dynamometer test) and flexibility (sit and reach test) and psychological aspects as depressive symptoms (BECK Inventory), body image (Body Image After Breast Cancer Questionnaire), self-esteem (Rosenberg), fatigue (FACT-F), pain (VAS), sexual function (FSFI) and sleep quality (Pittsburgh Sleep Quality Index). Discussion: In view of the high prevalence of breast cancer among women, the implementation a specific protocol of Pilates solo and belly dance for patients with breast cancer is important considering the needs to improve the quality of life, physical and psychological aspects of their life. Pilates solo and belly dance are two kinds of physical activity that involves mental and body concentration, music, upper limb movements, femininity, and social involvement. An intervention with these two physical activities could offer a choice of supportive care to breast cancer women undergoing treatment to improve quality of life, physical and psychological aspects. Trial registration: ClinicalTrials.gov Identifier: NCT03194997 (registration date: 12 August 2017). Universal Trial Number (World Health Organization): U1111-1195-1623. https://clinicaltrials.gov/ct2/show/NCT03194997

scholarly journals Pilates and dance to breast cancer patients undergoing treatment: study protocol for a randomized clinical trial – MoveMama study

2019 ◽  
Author(s):  
Leonessa Boing ◽  
Tatiana do Bem Fretta ◽  
Melissa de Carvalho Souza Vieira ◽  
Gustavo Soares Pereira ◽  
Jéssica Moratelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Body Image ◽  
Side Effects ◽  
Psychological Aspects ◽  
Control Group ◽  
Belly Dance ◽  
Breast Cancer Patients

Abstract Background: Breast cancer is a global public health issue and the side effects of the clinical treatment can decline the quality of life of these women. Therefore, a healthy lifestyle is essential to minimize the physical and psychological side effects of treatment. Physical activity has several benefits for breast cancer women and Pilates solo and belly dance can be an enjoyable type of physical activity for breast cancer women undergoing clinical treatment. The purpose of the study will be to provide a Pilates solo and a belly dance protocol (3x/16 weeks) for women undergoing breast cancer treatment and compare its effects with the control group. Methods: The participants will be allocated to either the intervention arm (Pilates solo or belly dance classes 3x/week for 16 weeks) or a control group (receipt of a booklet on physical activity for breast cancer patients and maintenance of habitual physical activity routine). The Pilates solo and belly dance classes will be divided into three stages: warm-up and stretching; the main stage and relaxation. Measurements of study outcomes will take place at baseline, post-intervention, 6-, 12- and 24-months (maintenance period). The data collection for both groups will occur with a questionnaire application and tests, covering general and clinical information, primary outcome will be quality of life (EORT QLQ C30 and BR23), secondary outcomes will be physical aspects as cardiorespiratory fitness (6-minute walk test and cycle ergometer), lymphedema (sum of arm circumference), physical activity (IPAQ short version), disabilities of the arm (DASH), range of motion (goniometer test), strength (dynamometer test) and flexibility (sit and reach test) and psychological aspects as depressive symptoms (BECK Inventory), body image (Body Image After Breast Cancer Questionnaire), self-esteem (Rosenberg), fatigue (FACT-F), pain (VAS), sexual function (FSFI) and sleep quality (Pittsburgh Sleep Quality Index). Discussion: In view of the high prevalence of breast cancer among women, the implementation a specific protocol of Pilates solo and belly dance for patients with breast cancer is important considering the needs to improve the quality of life, physical and psychological aspects of their life. Pilates solo and belly dance are two kinds of physical activity that involves mental and body concentration, music, upper limb movements, femininity, and social involvement. An intervention with these two physical activities could offer a choice of supportive care to breast cancer women undergoing treatment to improve quality of life, physical and psychological aspects. Trial registration: ClinicalTrials.gov Identifier: NCT03194997 (registration date: 12 August 2017). Universal Trial Number (World Health Organization): U1111-1195-1623. https://clinicaltrials.gov/ct2/show/NCT03194997

scholarly journals EFFECTS OF BELLY DANCING ON BODY IMAGE AND SELF-ESTEEM IN WOMEN WITH BREAST CANCER – PILOT STUDY

2019 ◽  
Vol 25 (6) ◽  
pp. 464-468 ◽  
Author(s):  
Micheli Carminatti ◽  
Leonessa Boing ◽  
Bruna Leite ◽  
Fabiana Flores Sperandio ◽  
Thaina Korpalski ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Physical Activity ◽  
Body Image ◽  
Self Esteem ◽  
The Body ◽  
Control Group ◽  
Study Group ◽  
Belly Dance ◽  
Total Period ◽  
Belly Dancing

ABSTRACT Introduction Breast cancer has innumerable consequences in women’s lives and physical activity can be beneficial during this period. Objectives To analyze the influence of belly dancing on the body image and self-esteem of women during and after breast cancer treatment. Methods Nineteen women diagnosed with breast cancer, divided into a control group (8 women) and a study group (11 women), who were under treatment or post-treatment at the Center for Oncological Research (CEPON), participated in the study. A questionnaire was used for data collection, divided into three blocks as follows: a) general information - sociodemographic and clinical characterization; b) body image - Body Image After Breast Cancer; and c) self-esteem - Rosenberg Self-Esteem Scale. The study group underwent a belly dance intervention consisting of 60-minute classes, twice a week, for a total period of 12 weeks. Women in the control group only maintained their routine activities. Results Significant changes were observed in the improvement of body image in the belly dance group in the pre- and post-intervention periods in the body stigma (p = 0.017) and transparency (p = 0.021) scales. There were no changes in regards to self-esteem. The control group had no changes in either body image or self-esteem. Conclusion The influence of belly dancing on the improvement of women’s body image was observed after 12 weeks of intervention. Thus, it is understood that physical activity may help these women after breast cancer, and should be encouraged by health professionals in this field. Level of evidence II; Therapeutic studies - Investigation of treatment results.

scholarly journals Does a ketogenic diet have any adverse effect on quality of life, physical activity, or biochemical factors in patients with breast cancer? A randomized controlled trial.

2020 ◽  
Author(s):  
Adeleh Khodabakhshi ◽  
Mohammad Esmaeil Akbari ◽  
Thomas N. Seyfried ◽  
Maryam Mahmoudi ◽  
Miriam Kalamian ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Dietary Intake ◽  
Locally Advanced ◽  
Control Group ◽  
Thyroid Function Tests ◽  
Ketogenic Diets ◽  
Global Quality Of Life

Abstract Introduction: Despite the potential benefits of ketogenic diets (KDs) for cancer, evidence of its effects on quality of life is lacking. This study has aimed to find out whether KD has adverse effects on quality of life, physical activity, and biomarkers in patients with breast cancer.Method: A total of 80 patients with locally advanced or metastatic breast cancer were randomly assigned to either a KD or a control group for this 12-week trial. Concurrent with the first, third, and fifth chemotherapy sessions (12-week), the quality of life, physical activity, and biomarkers (thyroid function tests, electrolytes, albumin, ammonia, ALP, lactate and serum ketones) were assessed. Dietary intake was also recorded on admission and the end of the treatment.Results: No significant differences were seen in the quality of life or physical activity between the two groups after 12 weeks; however, the KD group showed a better global quality of life compared to the control group at 6 weeks (P=0.02). Also, serum lactate and ALP levels decreased significantly in KD group compared to the control group after intervention (10.7±3 vs 13.3±4, 149±71 vs 240±164, P=0.02 and P=0.007, respectively). KD did not have any negative impact on thyroid hormones, electrolytes, or physical activity. Compliance among KD subjects ranged from 66.7% to 79.2% as assessed by dietary intake and serum ketones levels of >0.5.Conclusion: According to our results, chemotherapy combined with KD does not negatively impact the quality of life, physical activity, or biomarkers tracked during our study. Ketosis may improve the effectiveness of chemotherapy in patients with breast cancer in part by decreasing lactate and ALP.

scholarly journals Does a ketogenic diet have beneficial effects on quality of life, physical activity or biomarkers in patients with breast cancer: A randomized controlled clinical trial.

2020 ◽  
Author(s):  
adeleh khodabakhshi ◽  
Thomas N. Seyfried ◽  
Miriam Kalamian ◽  
maryam mahmoudi ◽  
Sayed Hossein Davoodi
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Dietary Intake ◽  
Control Group ◽  
Thyroid Function Tests ◽  
Beneficial Effects ◽  
Global Quality ◽  
Global Quality Of Life

Abstract Introduction: Despite recent interest in the use of ketogenic diets (KDs) for cancer, evidence of beneficial effects is lacking. This study examined the impact of a randomly assigned KD on quality of life, physical activity and biomarkers in patients with breast cancer.Method: A total of 80 patients with locally advanced or metastatic breast cancer and without a history of renal disease or diabetes were randomly assigned to either a KD or a control group for this 12-week trial. Concurrent with the first, third, and fifth chemotherapy sessions, quality of life, physical activity, and biomarkers (thyroid function tests, electrolytes, albumin, ammonia, ALP, lactate and serum ketones) were assessed. Dietary intake was also recorded on admission and the end of the treatment.Results: No significant differences were seen in quality of life or physical activity scores between the two groups after 12 weeks; however, the KD group showed higher global quality of life and physical activity scores compared to the control group at 6 weeks (P=0.02 P= 0.01). Also, serum lactate and ALP levels decreased significantly in the KD group compared to the control group at the end of the intervention (10.7±3 vs 13.3±4, 149±71 vs 240±164, P=0.02 and P=0.007, respectively). A significant inverse association was observed between total carbohydrate intake and serum beta-hydroxybutyrate at 12 weeks (r= -0.77 P <0.001). No significant differences between groups were observed in thyroid hormones, electrolytes, albumin, LDH or ammonia. Compliance among KD subjects ranged from 66.7% to 79.2% as assessed by dietary intake and serum ketones levels of >0.5.Conclusion: According to our results, besides a higher global quality of life and physical activity scores compared to the control group at 6 weeks, KD diet combined to chemotherapy in patients with breast cancer does not bring additional benefit about quality of life and physical activity at 12 weeks. However, decreases seen in levels of lactate and ALP in the KD group suggest that a KD may benefit patients with breast cancer.

scholarly journals PHYSICAL ACTIVITY AND QUALITY OF LIFE IN WOMEN WITH BREAST CANCER – A CROSS-SECTIONAL STUDY

2018 ◽  
Vol 24 (5) ◽  
pp. 377-381
Author(s):  
Leonessa Boing ◽  
Gustavo Soares Pereira ◽  
Melissa de Carvalho Souza Vieira ◽  
Taysi Seemann ◽  
Allana Alexandre Cardoso ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Physical Activity ◽  
Side Effects ◽  
Cancer Treatment ◽  
Vigorous Physical Activity ◽  
Breast Cancer Treatment ◽  
Clinical Treatment ◽  
Walking Time

ABSTRACT Introduction: Breast cancer treatment can cause different side effects on the quality of life of women. Physical activity, in turn, can reduce these side effects. Objective: To investigate the physical activity and quality of life of women during and after breast cancer treatment. Methods: Sample of 174 women (57.0±9.5 years) during or after clinical treatment for breast cancer. Interview questionnaire composed of general information, physical activity (IPAQ short version) and quality of life (EORTC QLQ-C30 and BR23). For statistical analysis chi-squared test or Fisher's exact test, student's t-test for independent samples, Mann-Whitney U test and multiple logistic regression analyses (p <0.05). Results: Most women did not achieve the physical activity guidelines, particularly those undergoing clinical treatment. Results showed longer walking time, moderate physical activity, vigorous physical activity, moderate + vigorous physical activity, and total physical activity among the women following completion of treatment. The quality of life scores were also higher among women after clinical treatment. Logistic regression indicated that every 10-minute increment to walking time results in a 19% decrease in the probability of worse functional capacity and a 26% decrease in the probability of worse symptoms associated with treatment side effects. Conclusion: During treatment, women with breast cancer undertake less physical activity and have worse quality of life. Walking appears to be an effective type of physical activity for these women, improving quality of life during and after breast cancer treatment. Level of evidence II; Prognostic studies - Investigation of the effect of patient characteristics on the disease outcome.

Quality of life assessment of oncologically treated patients because of breast cancer

2019 ◽  
Vol 9 (4) ◽  
pp. 14-20
Author(s):  
Aleksandra Trybulec ◽  
Filip Georgiew ◽  
Katarzyna Borowiec-Trybulec
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Body Image ◽  
Side Effects ◽  
Sexual Functioning ◽  
Personal Control ◽  
Sexual Pleasure ◽  
Life Assessment ◽  
Malignant Neoplasms

Introduction: Currently, in the world, breast cancer is recognized as one in four malignant neoplasms in women. It is the second most common cause of death in cancer patients. The disease, which is a threat to women’s lives, leads to the loss of personal control, during its duration it becomes everyday life with negative emotions such as uncertainty, anxiety and anxiety. Women have contact with a range of negative effects that the disease provides, causing them to resign and destructive to the psychophysical sphere. Disorders in the physical and mental aspect of body image, side effects of therapy, sexual relations with a partner and anxiety about health in the future are factors that have a huge impact on the quality of life of patients. The aim of the study was to assess the quality of life of women with breast cancer. Materials and methods: The quality of life of 40 women with breast cancer who underwent oncological treatment was assessed using the author’s questionnaire with 12 questions and QLQ-BR23 questionnaire with 23 questions.. Results and conclusions: Studies have shown that the biggest problem for women was the side effects of the treatment and the most common discomfort during radiation therapy. They are characterized by redness of the skin, general weakness and fatigue, which in turn later translated into, a change in the perception of their body image, a decrease in their attractiveness, a sense of comfort and confidence. The obtained results showed that the lowest quality of life of the respondents was registered in the domain determining future perspectives. The best result was recorded in the domain of sexual pleasure and sexual functioning. When assessing the quality of life of the respondents, it follows that patients with vocational education have a worse quality of life within the domain of breast symptoms. Employed persons surveyed obtained worse quality of life results in terms of sexual functioning and sexual pleasure. Considering the duration of illness of the respondents, there were no statistically significant differences affecting the quality of life.

scholarly journals The Effects of Individual Diet Therapy on Food Intake, Quality of Life, and Related Serum Proteins in Patients with Breast Cancer: A Randomized Clinical Trial

2021 ◽  
Author(s):  
Azadeh Fallah ◽  
Kiana Parnian ◽  
Hamid Abdolazimi ◽  
Sajjad Tezerji ◽  
Zohreh Mazloom
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Side Effects ◽  
Cancer Patients ◽  
Serum Proteins ◽  
Intervention Group ◽  
Diet Therapy ◽  
Control Group ◽  
Nutritional Needs

Background: In cancer patients, weight loss due to malnutrition has a significant impact on the patients’ treatment and quality of life. This study aimed to determine the appropriate therapeutic strategy to control the side effects of chemotherapy in patients with breast cancer to improve their health, quality of life, and nutritional status. Methods: In our prospective study, we examined gastric cancer patients who were Seventy patients undergoing chemotherapy were included and randomly divided into intervention (n=35) and control groups (n=35). The intervention group received an individualized diet according to their nutritional needs for eight weeks, and the control group received dietary advice on the side effects of chemotherapy. Malnutrition, nutritional barriers, and patients’ quality of life were evaluated by PG-SGA, nutritional barriers, and QLQ-C30 questionnaires. Serum proteins were also assessed at the beginning and the end of the study. Results: The patients’ mean age was 50.91±1.72 years in the intervention group and 51±1.35 in the control group. According to the PG-SGA questionnaire classification, 68.5% of patients had malnutrition at baseline. In the intervention group, the mean score of PG-SGA decreased, which indicated an improvement in patients’ nutritional status. Increased scores in the functional section of QLQC30 and a decrease in the symptom section of this questionnaire indicated the improved quality of life in patients undergoing treatment at the end of the intervention. Albumin (P<0.001) and hemoglobin (P<0.001) levels increased in the intervention group, while there were no significant changes in these variables of the control group. Serum levels of ferritin did not show significant changes in either the intervention or the control group. Conclusion: Identifying nutritional barriers in breast cancer patients and individual diet therapy based on these barriers and nutritional needs reduces nutritional barriers. Consequently, malnutrition would decline, and the quality of life may enhance in these patients.

scholarly journals The Chinese herb Xiaoaiping protects against breast cancer chemotherapy-induced alopecia and other side effects: a randomized controlled trial

2019 ◽  
Vol 47 (6) ◽  
pp. 2607-2614 ◽  
Author(s):  
Fujie Yu ◽  
Yuanmei Li ◽  
Jiaqun Zou ◽  
Lisha Jiang ◽  
Chun Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Side Effects ◽  
Cancer Patients ◽  
Chinese Herb ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Breast Cancer Patients ◽  
Wbc Count

Objective To investigate the effects of the Chinese herbal medicine Xiaoaiping to treat chemotherapy-induced side effects in breast cancer patients. Methods Ninety-three adult patients who attended our hospital and met the entry criteria from January 2016 to December 2017 were included. Patients were randomly divided into the control group (routine chemotherapy only) and the combined group (routine chemotherapy and Xiaoaiping). Demographic data and clinical variables were collected, and side effects including alopecia, nausea and vomiting, diarrhea, white blood cell (WBC) count, aspartate aminotransferase (AST) levels, and the quality of life were evaluated. Results Basic clinical characteristics were not different between the groups. There were significantly fewer patients with alopecia grade 3–4, but significantly more patients with alopecia grade 1–2, in the combined group compared with the control group. Disease-free time for alopecia was longer in the combined compared with the control group. Overall, the side effects were significantly more serious in the control compared with the combined group. Patients in the combined group had better quality of life than the control patients. Conclusion Xiaoaiping can improve alopecia, nausea and vomiting, and diarrhea symptoms, WBC count, AST levels, and the quality of life in breast cancer patients.

scholarly journals A Mobile Game for Patients With Breast Cancer for Chemotherapy Self-Management and Quality-of-Life Improvement: Randomized Controlled Trial

2018 ◽  
Vol 20 (10) ◽  
pp. e273 ◽  
Author(s):  
Hee Jun Kim ◽  
Sun Mi Kim ◽  
Heechul Shin ◽  
Joung-Soon Jang ◽  
Young In Kim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Side Effects ◽  
Patient Education ◽  
Psychological Status ◽  
Control Group ◽  
Drug Compliance ◽  
Mobile Games ◽  
Mobile Game

Background The application of game-based learning in clinical practice has shown potential advantages in previous studies. However, there have been little efforts to use smartphone-based mobile games in the management of adult patients with cancer. Objective The objective of our study was to evaluate if patient education using a mobile game may increase drug compliance, decrease physical side effects of chemotherapy, and improve psychological status in breast cancer patients. Methods A total of 76 patients with metastatic breast cancer who were planned to receive cytotoxic chemotherapy were enrolled in this trial. Study participants were randomly assigned to a mobile game play group (game group, n=36) or a conventional education group (control group, n=40) in a ratio of 1:1. The patients were unblinded and followed prospectively for 3 weeks. Outcome measures included time spent for education, compliance to medication, physical side effects, and psychological side effects including quality of life (QoL). Results Overall, 72 out of 76 patients completed the study after 3 weeks (95%). The subjects in the game group showed high levels of satisfaction with the app. The time spent playing the mobile game in the game group was longer than that spent for self-education in the control group (mean 22.2, SD 6.1 vs mean 5.5, SD 4.0 minutes a day; P<.001). The mobile game group showed better drug adherence (Korean version of the Medication Adherence Rating Scale; mean 7.6, SD 0.7 vs mean 6.5, SD 0.5; P<.001). The use of the mobile game was associated with lower rates of chemotherapy-related side effects, such as nausea, fatigue, numbness of hand or foot, and hair loss, than the control group. The game group exhibited better QoL during chemotherapy (mean 74.9, SD 3.5 vs mean 72.2, SD 5.3; P=.01). However, there were no significant differences in terms of depression and anxiety scales. Conclusions This study suggests the feasibility and potentiality of the use of smartphone mobile games for patients with breast cancer receiving chemotherapy. Education using a mobile game led to better patient education, improved drug compliance, decreased side effects, and better QoL compared with conventional education. Mobile games can be used as easy, fun, and effective measures for patient education and have the potential to improve treatment outcomes. Trial Registration ClinicalTrials.gov NCT03205969; http://clinicaltrials.gov/ct2/show/NCT03205969 (Archived by WebCite at http://www.webcitation.org/71jfSBOq9).

Sign in / Sign up

Export Citation Format

Share Document