scholarly journals Cardiovascular risk factor burden in Africa and the Middle East across country income categories: a post hoc analysis of the cross-sectional Africa Middle East Cardiovascular Epidemiological (ACE) study

2018 ◽  
Vol 76 (1) ◽  
Author(s):  
Frederick J. Raal ◽  
Alawi A. Alsheikh-Ali ◽  
Mohamed I. Omar ◽  
Wafa Rashed ◽  
Omar Hamoui ◽  
...  
PLoS ONE ◽  
2014 ◽  
Vol 9 (8) ◽  
pp. e102830 ◽  
Author(s):  
Alawi A. Alsheikh-Ali ◽  
Mohamed I. Omar ◽  
Frederick J. Raal ◽  
Wafa Rashed ◽  
Omar Hamoui ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. e015340 ◽  
Author(s):  
Guoju Li ◽  
Guanghong Guo ◽  
Wenrui Wang ◽  
Ke Wang ◽  
Hailing Wang ◽  
...  

Author(s):  
Ghazi Radaideh ◽  
Nikolaos Tzemos ◽  
Talaha Mubarak Ali ◽  
Yasser Eldershaby ◽  
Jean Joury ◽  
...  

<p><strong>Background: </strong><span style="font-family: Calibri;">T</span>he Africa Middle East (AfME) Cardiovascular Epidemiological (ACE) study demonstrated that cardiovascular risk factors are highly prevalent among relatively young adult outpatients attending general practice clinics across AfME regions.</p><p><strong>Objective: </strong>Based on the broader AfME estimates from the ACE Study, this sub-analysis evaluated the prevalence of cardiovascular risk factors in the United Arab Emirates (UAE), particularly in rural and urban cohorts attending general practice clinics.</p><p><strong>Methods: </strong>Data from the cross-sectional ACE study were used: stable, adult outpatients attending general practice clinics in the UAE. Prevalence of six CV risk factors were analyzed: hypertension, diabetes, dyslipidemia, obesity, smoking, abdominal obesity. Rural populations were defined as living &gt;50km from urban centers, or lack of transportation.</p><p><strong>Results: </strong>In this cohort of 495 patients (aged 45.1 years; 49.8% female) from the UAE, a high prevalence of abdominal obesity (71.5%) and dyslipidemia (74.0%) was found. Nearly half of patients had hypertension (43.0%) and one-third diabetes (32.4%). Nearly all outpatients (92.9%) had ≥1 modifiable risk factor (74.9% had ≥1, 59.7% had ≥3). Observations were similar by gender, and across urban and rural centers. Many outpatients with pre-existing hypertension or dyslipidemia did not meet recognized blood pressure or low-density lipoprotein cholesterol goals.</p><p><strong>Conclusions: </strong>Cardiovascular risk factors are prevalent among relatively young adult, clinically stable outpatients attending outpatient clinics across the UAE. These findings support targeted screening of outpatients visiting a general practitioner, which may provide opportunity for early discovery and ongoing management of risk factors, including recommending lifestyle changes. The ACE trial is registered under NCT01243138.</p>


1999 ◽  
Vol 31 (Supplement) ◽  
pp. S379
Author(s):  
S. V. Jaque ◽  
R. A. Wiswell ◽  
S. A. Hawkins ◽  
K. M. Tarpenning ◽  
N. L. Constantino ◽  
...  

Author(s):  
Pilar de Lucas-Ramos ◽  
Jose Luis Izquierdo Alonso ◽  
jESÚS Fernandez Frances ◽  
Paz Vaquero Lopez ◽  
Jose Miguel Rodriguez Gonzalez-Moro

2009 ◽  
Vol 5 (1) ◽  
pp. 10 ◽  
Author(s):  
Rhonda BeLue ◽  
Titilayo A Okoror ◽  
Juliet Iwelunmor ◽  
Kelly D Taylor ◽  
Arnold N Degboe ◽  
...  

Hypertension ◽  
2015 ◽  
Vol 66 (suppl_1) ◽  
Author(s):  
Janet M Catov ◽  
Steven E Reis ◽  
Matthew F Muldoon ◽  
Roberta B Ness ◽  
Lananh Nguyen ◽  
...  

Objective: To investigate whether preterm birth and placental evidence of malperfusion is associated with subclinical atherosclerosis and a higher cardiovascular risk factor burden 4 to 12 years after pregnancy. Methods: A cohort of women with preterm (n=119) and term births (n=242), mean age 38 years, was examined on average eight years after pregnancy for carotid artery intima-media thickness (IMT), fasting lipids, blood pressure and inflammatory markers (C-reactive protein [hsCRP] and Interleukin-6 [IL-6]). Pregnancy characteristics included placental pathology evidence of malperfusion (vasculopathy, infarct, advanced villous maturation, perivillous fibrin, fibrin deposition), infection (chorioamnionitis, funisitis, deciduitus), villitis (chronic inflammation), fetal thrombosis or chorangiosis. Vascular-mediated preterm births were those with malperfusion lesions, and by design, those with preeclampsia were excluded. Results: Women with malperfusion lesions had a higher mean carotid IMT (+0.055 cm), total cholesterol (+17.49 mg/dl), LDL-C (+11.44), triglycerides (+17%), apolipoprotein-B (+8.95) and systolic and diastolic blood pressure (+4.58/+2.62 mmHg) compared to women with term births, independent of age, race, smoking and adiposity assessed before and after pregnancy (all p<0.05). Women with preterm birth and evidence of malperfusion accompanied by other lesions related to infection or chronic inflammation had the most atherogenic profile after pregnancy, and carotid IMT differences were independent of traditional risk factors (+0.04 cm; p=0.027). Conclusions: Vascular-mediated preterm birth is associated with maternal subclinical atherosclerosis and a higher cardiovascular risk factor burden in the decade after pregnancy compared to term birth. The placenta may offer unique insight into how pregnancy complications can portend the emergence of maternal cardiovascular disease.


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