Robustness of magnetic resonance radiomic features to pixel size resampling and interpolation in patients with cervical cancer

Abstract Background Radiomics is a promising field in oncology imaging. However, the implementation of radiomics clinically has been limited because its robustness remains unclear. Previous CT and PET studies suggested that radiomic features were sensitive to variations in pixel size and slice thickness of the images. The purpose of this study was to assess robustness of magnetic resonance (MR) radiomic features to pixel size resampling and interpolation in patients with cervical cancer. Methods This retrospective study included 254 patients with a pathological diagnosis of cervical cancer stages IB to IVA who received definitive chemoradiation at our institution between January 2006 and June 2020. Pretreatment MR scans were analyzed. Each region of cervical cancer was segmented on the axial gadolinium-enhanced T1- and T2-weighted images; 107 radiomic features were extracted. MR scans were interpolated and resampled using various slice thicknesses and pixel spaces. Intraclass correlation coefficients (ICCs) were calculated between the original images and images that underwent pixel size resampling (OP), interpolation (OI), or pixel size resampling and interpolation (OP+I) as well as among processed image sets with various pixel spaces (P), various slice thicknesses (I), and both (P + I). Results After feature standardization, ≥86.0% of features showed good robustness when compared between the original and processed images (OP, OI, and OP+I) and ≥ 88.8% of features showed good robustness when processed images were compared (P, I, and P + I). Although most first-order, shape, and texture features showed good robustness, GLSZM small-area emphasis-related features and NGTDM strength were sensitive to variations in pixel size and slice thickness. Conclusion Most MR radiomic features in patients with cervical cancer were robust after pixel size resampling and interpolation following the feature standardization process. The understanding regarding the robustness of individual features after pixel size resampling and interpolation could help future radiomics research.

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Magnetic resonance imaging based coracoid morphology and its associations with subscapularis tears: a new index

Shoulder & Elbow ◽

10.1177/1758573217744170 ◽

2017 ◽

Vol 11 (1_suppl) ◽

pp. 52-58 ◽

Cited By ~ 2

Author(s):

Adam C. Watson ◽

Richard P. Jamieson ◽

Andrew C. Mattin ◽

Richard S. Page

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Sagittal Plane ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Resonance Imaging ◽

Intraclass Correlation Coefficients ◽

Arm Position ◽

Magnetic Resonance Imaging Mri

Background We aimed to assess the validity of magnetic resonance imaging (MRI) in assessing the subcorocoid space and determine the validity of novel sagittal plane subcorocoid space measurements. Methods We assessed 33 arthroscopically proven subscapularis tears with MRIs compared to 33 (instability) controls with normal subscapularis tendons. Three examiners analyzed MRIs for seven static indices of corocoid morphology, in axial and sagittal planes. We explored reviewer variation using intraclass correlation coefficients (ICC) and differences between the two groups was explored using t-tests. Results Groups were similar in characteristics but different in age (cases = 53, controls = 23). ICC showed good (2/7) or excellent (5/7) reliability. Small differences(<1.6 mm) were identified between subscapularis tears and controls in coraco–humeral distance, in axial ( p = 0.092) and sagittal planes ( p = 0.045). There were statistically significant differences between groups when analyzing the angular projection of the coracoid from the glenoid, in both sagittal ( p < 0.0001) and axial planes ( p = 0.045). Conclusions Acute inferior angulation of the corocoid in the sagittal plane may be associated with subscapularis tears. Static indices are measured within the scapula and not affected by arm position. MRI reliably provided a platform to assess the coracoid. Based on this, we currently consider corocoplasty in patients with subscapularis tears and a sagittal coroco–glenoid angle <60o to reduce potential impingement.

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The Longitudinal Reliability and Responsiveness of the OMERACT Hand Osteoarthritis Magnetic Resonance Imaging Scoring System (HOAMRIS)

The Journal of Rheumatology ◽

10.3899/jrheum.140983 ◽

2015 ◽

Vol 42 (12) ◽

pp. 2486-2491 ◽

Cited By ~ 17

Author(s):

Ida K. Haugen ◽

Iris Eshed ◽

Frederique Gandjbakhch ◽

Violaine Foltz ◽

Mikkel Østergaard ◽

...

Keyword(s):

Magnetic Resonance ◽

Scoring System ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Hand Osteoarthritis ◽

Cross Sectional ◽

Change Scores ◽

Intraclass Correlation Coefficients ◽

Smallest Detectable Change ◽

Sum Scores

Objective.To evaluate the interreader reliability of change scores and the responsiveness of the OMERACT Hand Osteoarthritis (OA) Magnetic Resonance Image (MRI) Scoring System (HOAMRIS).Methods.Paired MRI (baseline and 5-yr followup) from 20 patients with hand OA were scored with known time sequence by 3 readers according to the HOAMRIS: Synovitis, erosive damage, cysts, osteophytes, cartilage space loss, malalignment, and bone marrow lesions (BML; 0–3 scales with 0.5 increments for synovitis, erosive damage, and BML). Interreader reliability for status and change scores were assessed by intraclass correlation coefficients (ICC), percentage exact agreement and percentage close agreement (PEA/PCA), and smallest detectable change (SDC). Responsiveness was assessed by standardized response means (SRM).Results.Cross-sectional interreader ICC were good to very good (≥ 0.74) for all features except synovitis, cysts, and malalignment (ICC 0.50–0.58). The range of change values was small, leading to low ICC for change scores. The SDC values for sum scores (total range 0–24) varied between 1.97–3.05 (except 1.08 for malalignment). For status scores, PEA/PCA on scores in individual joints across the readers were 8.1–50.0 and 43.8–78.1, respectively. Similarly, PEA/PCA for change scores were 20.6–63.8 and 66.3–93.1, respectively. All features except cysts and BML demonstrated good responsiveness with higher SRM for sum scores (range 0.46–1.62) than for scores in individual joints (range 0.24–0.73).Conclusion.Good to very good interreader ICC values were found for cross-sectional readings, whereas the longitudinal reliability was lower because of a smaller range of change scores. All features, except cysts and BML, showed good responsiveness.

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The Transaxial Orientation Is Superior to Both the Short Axis and Horizontal Long Axis Orientations for Determining Right Ventricular Volume and Ejection Fraction Using Simpson's Method with Cardiac Magnetic Resonance

ISRN Cardiology ◽

10.1155/2013/268697 ◽

2013 ◽

Vol 2013 ◽

pp. 1-9 ◽

Cited By ~ 2

Author(s):

Michael K. Atalay ◽

Kevin J. Chang ◽

David J. Grand ◽

Shawn Haji-Momenian ◽

Jason T. Machan ◽

...

Keyword(s):

Cardiac Magnetic Resonance ◽

Magnetic Resonance ◽

Ejection Fraction ◽

Right Ventricular ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Ventricular Volume ◽

Short Axis ◽

Intraclass Correlation Coefficients ◽

Significant Difference

We sought to determine which of the three orientations is the most reliable and accurate for quantifying right ventricular (RV) volume and ejection fraction (EF) by cardiac magnetic resonance using Simpson’s method. We studied 20 patients using short axis (SA), transaxial (TA), and horizontal long axis (HLA) orientations. Three readers independently traced RV endocardial contours at end-diastole and end-systole for each orientation. End-diastolic volumes (EDVs), end-systolic volumes (ESVs), and EF were calculated and compared with the 3D piecewise smooth subdivision surface (PSSS) method. The intraclass correlation coefficients among the 3 readers for EDV, ESV, and EF were 0.92, 0.82, and 0.42, respectively, for SA, 0.95, 0.92, and 0.67 for TA, and 0.85, 0.93, and 0.69 for HLA. For mean data there was no significant difference between TA and PSSS for EDV (−2.6%, 95% CI: −8.2 to 3.3%), ESV (−5.9%, −15.2 to 4.5%), and EF (1.7%, −1.5 to 4.9%). HLA was accurate for ESV (−8.9%, −18.5 to 1.8%) and EF (−0.7%, −3.8 to 2.5%) but significantly underestimated EDV (−9.8, −16.6 to −2.4%). SA was accurate for EDV (0.5%, −6.0 to 7.5%) but overestimated ESV (10.5%, 0.1 to 21.9%) and had poor interrater reliability for EF. Conclusions. The TA orientation provides the most reliable and accurate measures of EDV, ESV, and EF.

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Longitudinal Reliability of the OMERACT Thumb Base Osteoarthritis Magnetic Resonance Imaging Scoring System (TOMS)

The Journal of Rheumatology ◽

10.3899/jrheum.180949 ◽

2018 ◽

Vol 46 (9) ◽

pp. 1228-1231

Author(s):

Féline P.B. Kroon ◽

Sjoerd van Beest ◽

Frédérique Gandjbakhch ◽

Charles G. Peterfy ◽

Su Chen ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Scoring System ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Hand Osteoarthritis ◽

Resonance Imaging ◽

Intraclass Correlation Coefficients ◽

Smallest Detectable Change ◽

Magnetic Resonance Imaging Mri

Objective.To assess the longitudinal reliability of the Outcome Measures in Rheumatology (OMERACT) Thumb base Osteoarthritis Magnetic resonance imaging (MRI) Scoring system (TOMS).Methods.Paired MRI of patients with hand osteoarthritis were scored in 2 exercises (6-mo and 2-yr followup) for synovitis, subchondral bone defects (SBD), osteophytes, cartilage assessment, bone marrow lesions (BML), and subluxation. Interreader reliability of delta scores was assessed.Results.Little change occurred. Average-measure intraclass correlation coefficients were good-excellent (≥ 0.71), except synovitis (0.55–0.83) and carpometacarpal-1 osteophytes/cartilage assessment (0.47/0.39). Percentage exact/close agreement was 52–92%/68–100%, except BML in 2 years (28%/64–76%). Smallest detectable change was below the scoring increment, except in SBD and BML.Conclusion.TOMS longitudinal reliability was moderate-good. Limited change hampered assessment.

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Interobserver Reliability Using the Phonetic Level Evaluation With Severely and Profoundly Hearing-Impaired Children

Journal of Speech Language and Hearing Research ◽

10.1044/jshr.3405.989 ◽

1991 ◽

Vol 34 (5) ◽

pp. 989-999 ◽

Cited By ~ 6

Author(s):

Stephanie Shaw ◽

Truman E. Coggins

Keyword(s):

Interrater Reliability ◽

Interobserver Reliability ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Hearing Impaired ◽

Intraclass Correlation Coefficients ◽

Assessment Measure ◽

Impaired Children ◽

Speech Assessment ◽

Hearing Impaired Children

This study examines whether observers reliably categorize selected speech production behaviors in hearing-impaired children. A group of experienced speech-language pathologists was trained to score the elicited imitations of 5 profoundly and 5 severely hearing-impaired subjects using the Phonetic Level Evaluation (Ling, 1976). Interrater reliability was calculated using intraclass correlation coefficients. Overall, the magnitude of the coefficients was found to be considerably below what would be accepted in published behavioral research. Failure to obtain acceptably high levels of reliability suggests that the Phonetic Level Evaluation may not yet be an accurate and objective speech assessment measure for hearing-impaired children.

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Is there a relationship between the overhead press and split jerk maximum performance? Influence of sex

International Journal of Sports Science & Coaching ◽

10.1177/17479541211020452 ◽

2021 ◽

pp. 174795412110204

Author(s):

Marcos A Soriano ◽

G Gregory Haff ◽

Paul Comfort ◽

Francisco J Amaro-Gahete ◽

Antonio Torres-González ◽

...

Keyword(s):

Confidence Intervals ◽

Body Mass ◽

Upper Limb ◽

High Reliability ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Training Experience ◽

Maximum Performance ◽

Repetition Maximum ◽

Intraclass Correlation Coefficients

The aims of this study were to (I) determine the differences and relationship between the overhead press and split jerk performance in athletes involved in weightlifting training, and (II) explore the magnitude of these differences in one-repetition maximum (1RM) performances between sexes. Sixty-one men (age: 30.4 ± 6.7 years; height: 1.8 ± 0.5 m; body mass 82.5 ± 8.5 kg; weightlifting training experience: 3.7 ± 3.5 yrs) and 21 women (age: 29.5 ± 5.2 yrs; height: 1.7 ± 0.5 m; body mass: 62.6 ± 5.7 kg; weightlifting training experience: 3.0 ± 1.5 yrs) participated. The 1RM performance of the overhead press and split jerk were assessed for all participants, with the overhead press assessed on two occasions to determine between-session reliability. The intraclass correlation coefficients (ICC) and 95% confidence intervals showed a high reliability for the overhead press ICC = 0.98 (0.97 – 0.99). A very strong correlation and significant differences were found between the overhead press and split jerk 1RM performances for all participants (r = 0.90 [0.93 – 0.85], 60.2 ± 18.3 kg, 95.7 ± 29.3 kg, p ≤ 0.001). Men demonstrated stronger correlations between the overhead press and split jerk 1RM performances (r = 0.83 [0.73-0.90], p ≤ 0.001) compared with women (r = 0.56 [0.17-0.80], p = 0.008). These results provide evidence that 1RM performance of the overhead press and split jerk performance are highly related, highlighting the importance of upper-limb strength in the split jerk maximum performance.

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Patient-Reported Dysphagia in Adults with Eosinophilic Esophagitis: Translation and Validation of the Swedish Eosinophilic Esophagitis Activity Index

Dysphagia ◽

10.1007/s00455-021-10277-5 ◽

2021 ◽

Author(s):

Sofie Albinsson ◽

Lisa Tuomi ◽

Christine Wennerås ◽

Helen Larsson

Keyword(s):

Eosinophilic Esophagitis ◽

Activity Index ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Control Group ◽

Cronbach’S Alpha ◽

Intraclass Correlation Coefficients ◽

Cronbach's Alpha ◽

Patient Reported ◽

Eortc Qlq

AbstractThe lack of a Swedish patient-reported outcome instrument for eosinophilic esophagitis (EoE) has limited the assessment of the disease. The aims of the study were to translate and validate the Eosinophilic Esophagitis Activity Index (EEsAI) to Swedish and to assess the symptom severity of patients with EoE compared to a nondysphagia control group. The EEsAI was translated and adapted to a Swedish cultural context (S-EEsAI) based on international guidelines. The S-EEsAI was validated using adult Swedish patients with EoE (n = 97) and an age- and sex-matched nondysphagia control group (n = 97). All participants completed the S-EEsAI, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Oesophageal Module 18 (EORTC QLQ-OES18), and supplementary questions regarding feasibility and demographics. Reliability and validity of the S-EEsAI were evaluated by Cronbach’s alpha and Spearman correlation coefficients between the domains of the S-EEsAI and the EORTC QLQ-OES18. A test–retest analysis of 29 patients was evaluated through intraclass correlation coefficients. The S-EEsAI had sufficient reliability with Cronbach’s alpha values of 0.83 and 0.85 for the “visual dysphagia question” and the “avoidance, modification and slow eating score” domains, respectively. The test–retest reliability was sufficient, with good to excellent intraclass correlation coefficients (0.60–0.89). The S-EEsAI domains showed moderate correlation to 6/10 EORTC QLQ-OES18 domains, indicating adequate validity. The patient S-EEsAI results differed significantly from those of the nondysphagia controls (p < 0.001). The S-EEsAI appears to be a valid and reliable instrument for monitoring adult patients with EoE in Sweden.

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Diagnosis of left ventricular hypertrophy using non-ECG-gated 15O-water PET

Journal of Nuclear Cardiology ◽

10.1007/s12350-021-02734-3 ◽

2021 ◽

Author(s):

Jens Sörensen ◽

Jonny Nordström ◽

Tomasz Baron ◽

Stellan Mörner ◽

Sven-Olof Granstam ◽

...

Keyword(s):

Method Development ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Roc Curves ◽

Left Ventricular ◽

Intraclass Correlation Coefficients ◽

Concentric Hypertrophy ◽

2D Echocardiography ◽

Positron Emission ◽

Septal Wall Thickness

Abstract Aim To develop a method for diagnosing left ventricular (LV) hypertrophy from cardiac perfusion 15O-water positron emission tomography (PET). Methods We retrospectively pooled data from 139 subjects in four research cohorts. LV remodeling patterns ranged from normal to severe eccentric and concentric hypertrophy. 15O-water PET scans (n = 197) were performed with three different PET devices. A low-end scanner (66 scans) was used for method development, and remaining scans with newer devices for a blinded evaluation. Dynamic data were converted into parametric images of perfusable tissue fraction for semi-automatic delineation of the LV wall and calculation of LV mass (LVM) and septal wall thickness (WT). LVM and WT from PET were compared to cardiac magnetic resonance (CMR, n = 47) and WT to 2D-echocardiography (2DE, n = 36). PET accuracy was tested using linear regression, Bland–Altman plots, and ROC curves. Observer reproducibility were evaluated using intraclass correlation coefficients. Results High correlations were found in the blinded analyses (r ≥ 0.87, P < 0.0001 for all). AUC for detecting increased LVM and WT (> 12 mm and > 15 mm) was ≥ 0.95 (P < 0.0001 for all). Reproducibility was excellent (ICC ≥ 0.93, P < 0.0001). Conclusion 15O-water PET might detect LV hypertrophy with high accuracy and precision.

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Intersession reliability of GPS-based and accelerometer-based physical variables in small-sided games with and without the offside rule

Proceedings of the Institution of Mechanical Engineers Part P Journal of Sports Engineering and Technology ◽

10.1177/1754337120987646 ◽

2021 ◽

pp. 175433712098764

Author(s):

Igor Junio de Oliveira Custódio ◽

Gibson Moreira Praça ◽

Leandro Vinhas de Paula ◽

Sarah da Glória Teles Bredt ◽

Fabio Yuzo Nakamura ◽

...

Keyword(s):

Root Mean Square ◽

Global Positioning System ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Mean Square ◽

Physical Demands ◽

Intraclass Correlation Coefficients ◽

Total Distance ◽

Global Positioning ◽

High Level

This study aimed to analyze the intersession reliability of global positioning system (GPS-based) distances and accelerometer-based (acceleration) variables in small-sided soccer games (SSG) with and without the offside rule, as well as compare variables between the tasks. Twenty-four high-level U-17 soccer athletes played 3 versus 3 (plus goalkeepers) SSG in two formats (with and without the offside rule). SSG were performed on eight consecutive weeks (4 weeks for each group), twice a week. The physical demands were recorded using a GPS with an embedded triaxial accelerometer. GPS-based variables (total distance, average speed, and distances covered at different speeds) and accelerometer-based variables (Player Load™, root mean square of the acceleration recorded in each movement axis, and the root mean square of resultant acceleration) were calculated. Results showed that the inclusion of the offside rule reduced the total distance covered (large effect) and the distances covered at moderate speed zones (7–12.9 km/h – moderate effect; 13–17.9 km/h – large effect). In both SSG formats, GPS-based variables presented good to excellent reliability (intraclass correlation coefficients – ICC > 0.62) and accelerometer-based variables presented excellent reliability (ICC values > 0.89). Based on the results of this study, the offside rule decreases the physical demand of 3 versus 3 SSG and the physical demands required in these SSG present high intersession reliability.

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Assessment of reliability and validity of the 5-scale grading system of the point-of-care immunoassay for tear matrix metalloproteinase-9

Scientific Reports ◽

10.1038/s41598-021-92020-6 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Minjeong Kim ◽

Ja Young Oh ◽

Seon Ha Bae ◽

Seung Hyeun Lee ◽

Won Jun Lee ◽

...

Keyword(s):

Matrix Metalloproteinase ◽

Calibration Curve ◽

Point Of Care ◽

Interobserver Reliability ◽

Intraclass Correlation ◽

Reliability And Validity ◽

Correlation Coefficients ◽

Grading System ◽

Intraclass Correlation Coefficients ◽

The Difference

AbstractWe evaluated the reliability and validity of the 5-scale grading system to interpret the point-of-care immunoassay for tear matrix metalloproteinase (MMP)-9. Six observers graded red bands of photographs of the readout window in MMP-9 immunoassay kit (InflammaDry) two times with 2-week interval based on the 5-scale grading system (i.e. grade 0–4). Interobserver and intraobserver reliability were evaluated using intraclass correlation coefficients. The interobserver agreements were analyzed according to the severity of tear MMP-9 expression. To validate the system, a concentration calibration curve was made using MMP-9 solutions with reference concentrations, then the distribution of MMP-9 concentrations was analyzed according to the 5-scale grading system. Both intraobserver and interobserver reliability was excellent. The readout grades were significantly correlated with the quantified colorimetric densities. The interobserver variance of readout grades had no correlation with the severity of the measured densities. The band density continued to increase up to a maximal concentration (i.e. 5000 ng/mL) according to the calibration curve. The difference of grades reflected the change of MMP-9 concentrations sensitively, especially between grade 2 and 4. Together, our data indicate that the subjective 5-scale grading system in the point-of-care MMP-9 immunoassay is an easy and reliable method with acceptable accuracy.

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