scholarly journals Three-step one-way model in terahertz biomedical detection

PhotoniX ◽  
2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Yan Peng ◽  
Jieli Huang ◽  
Jie Luo ◽  
Zhangfan Yang ◽  
Liping Wang ◽  
...  
Keyword(s):  
Clinical Medicine ◽  
Detection Method ◽  
Flow Analysis ◽  
Effective Characteristic ◽  
Disease Biomarkers ◽  
Terahertz Detection ◽  
Terahertz Technology ◽  
Terahertz Spectrum ◽  
Human Sample ◽  
Biomedical Detection

AbstractTerahertz technology has broad application prospects in biomedical detection. However, the mixed characteristics of actual samples make the terahertz spectrum complex and difficult to distinguish, and there is no practical terahertz detection method for clinical medicine. Here, we propose a three-step one-way terahertz model, presenting a detailed flow analysis of terahertz technology in the biomedical detection of renal fibrosis as an example: 1) biomarker determination: screening disease biomarkers and establishing the terahertz spectrum and concentration gradient; 2) mixture interference removal: clearing the interfering signals in the mixture for the biomarker in the animal model and evaluating and retaining the effective characteristic peaks; and 3) individual difference removal: excluding individual interference differences and confirming the final effective terahertz parameters in the human sample. The root mean square error of our model is three orders of magnitude lower than that of the gold standard, with profound implications for the rapid, accurate and early detection of diseases.

scholarly journals Three-Step One-Way Model in Terahertz Biomedical Detection

2021 ◽  
Author(s):  
Yan Peng ◽  
Jieli Huang ◽  
Jie Luo ◽  
Zhangfan Yang ◽  
Liping Wang ◽  
...  
Keyword(s):  
Detection Method ◽  
Flow Analysis ◽  
Effective Characteristic ◽  
Disease Biomarkers ◽  
Terahertz Detection ◽  
Terahertz Technology ◽  
Medical Clinics ◽  
Terahertz Spectrum ◽  
Human Sample ◽  
Biomedical Detection

Abstract Terahertz technology has broad application prospects in biomedical detection. However, the mixed characteristics of actual samples make the terahertz spectrum complex and difficult to distinguish, and there is no practical terahertz detection method for medical clinics. Here, we propose a three-step one-way terahertz model, presenting a detailed flow analysis of terahertz technology in the biomedical detection of renal fibrosis as an example: 1) biomarker determination: screening disease biomarkers and establishing the terahertz spectrum and concentration gradient; 2) mixture interference removal: clearing the interfering signals in the mixture for the biomarker in the animal model and evaluating and retaining the effective characteristic peaks; and 3) individual difference removal: excluding individual interference differences and confirming the final effective terahertz parameters in the human sample. The root mean square error of our model is three orders of magnitude lower than that of the gold standard, with profound implications for the rapid, accurate and early detection of diseases.

Research on Three Fierce Exploders Reflected Terahertz Spectrum

2013 ◽  
Vol 760-762 ◽  
pp. 492-496 ◽  
Author(s):  
Gao Wang ◽  
Jian Quan Yao ◽  
De Gang Xu ◽  
Gao Wang ◽  
Xiao Fang Ren
Keyword(s):  
Rapid Development ◽  
Terahertz Technology ◽  
Terahertz Spectrum ◽  
Spectrum Characteristics ◽  
Application Fields

The rapid development of the Terahertz technology has been the essential focus among all application fields. In order to applying the spectral technology to the security and analyzing all exploders spectrum characteristics, the paper aims to three exploders spectrums researches including the HNS, DNMT and DNAN. The three reflected spectrums are tested and analyzed, using the most advanced portable terahertz spectrometer, and the absorption peaks among 0.1~2.5THz are determined successfully.

scholarly journals Terahertz Characteristics of Magnetic Fluid Based on Microfluidic Technology

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Xinyuan Zhao ◽  
Guoyang Wang ◽  
Siyu Shao ◽  
Qinghao Meng ◽  
Jiahui Wang ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Electric Field ◽  
Electric Fields ◽  
Field Intensity ◽  
Magnetic Fluid ◽  
Terahertz Technology ◽  
Terahertz Spectrum ◽  
Microfluidic Technology ◽  
Terahertz Transmission ◽  
The Magnetic Field

Magnetic fluid is a new functional material with both liquid fluidity and solid magnetism, which has important application value in medicine, biology, and so on. In this study, terahertz technology and microfluidic technology were combined to investigate the terahertz transmission characteristics of a magnetic fluid in different magnetic fields and different electric fields. In the external magnetic field, the intensity of the terahertz spectrum increased with an increase in the magnetic field intensity, and the response to the magnetic field in different directions was different. Under the applied electric field, the intensity of the terahertz spectrum decreased with an increase in the electric field intensity. This method is convenient for studying the terahertz characteristics of magnetic fluid and provides technical support for in-depth studies of magnetic fluid.

Real-Time Early Detection NTP Amplification Attack

2019 ◽  
Vol 3 (1) ◽  
pp. 76-84
Author(s):  
Gede Barkah Widagdo
Keyword(s):  
Early Detection ◽  
Real Time ◽  
Detection Method ◽  
Flow Analysis ◽  
Legitimate User ◽  
Monitoring Tools ◽  
Packet Header ◽  
Ddos Detection ◽  
Ip Packet

This paper is the initials of DDoS mitigation, the goal of this research is to detect NTP Amplification as early as possible so that the victim have a data to do further eskalation process. We knows that the goal of the attacker using NTP Amplification Attack is to exhaust the bandwidth of the victim, in this research also simulate an NTP amplification scenario and detection method; the scenario is the attacker sends requests with spoofed IP MONLIST victim to the compromised NTP server NTP server then responds the large volumes of traffic (amplified traffic) towards Victim to consume the bandwidth so as the legitimate user could not access the services. We put DDoS detection device side of the victim, we combine several monitoring tools to detect NTP amplification i.e bandwidth gauge and netflow analyzer. Netflow analyzer (flow analysis) conduct analysis IP packet header that is sent by the router as a flow-exporter. In our experiment, we could perform early detection of the NTP amplification less than 2 minute.

Solid-phase immunoelectron microscopy for rapid diagnosis of enteroviruses

1984 ◽  
Vol 42 ◽  
pp. 226-227 ◽  
Author(s):  
K. Pegg-Feige ◽  
F. W. Doane
Keyword(s):  
Electron Microscopy ◽  
Cell Culture ◽  
Immunoelectron Microscopy ◽  
Detection Method ◽  
Solid Phase ◽  
Protein A ◽  
Plant Viruses ◽  
Rapid Diagnosis ◽  
Virus Diagnosis ◽  
Antiviral Antibody

Immunoelectron microscopy (IEM) applied to rapid virus diagnosis offers a more sensitive detection method than direct electron microscopy (DEM), and can also be used to serotype viruses. One of several IEM techniques is that introduced by Derrick in 1972, in which antiviral antibody is attached to the support film of an EM specimen grid. Originally developed for plant viruses, it has recently been applied to several animal viruses, especially rotaviruses. We have investigated the use of this solid phase IEM technique (SPIEM) in detecting and identifying enteroviruses (in the form of crude cell culture isolates), and have compared it with a modified “SPIEM-SPA” method in which grids are coated with protein A from Staphylococcus aureus prior to exposure to antiserum.

Drug Induced Changes in Cell Organelles

1968 ◽  
Vol 26 ◽  
pp. 110-111
Author(s):  
Sarah A. Luse
Keyword(s):  
Clinical Medicine ◽  
Cell Organelles ◽  
Riboflavin Deficiency ◽  
Drug Induced ◽  
New Era ◽  
Health And Disease ◽  
In The Beginning ◽  
Cellular Pathology ◽  
Induced Changes ◽  
The Impact

In the mid-nineteenth century Virchow revolutionized pathology by introduction of the concept of “cellular pathology”. Today, a century later, this term has increasing significance in health and disease. We now are in the beginning of a new era in pathology, one which might well be termed “organelle pathology” or “subcellular pathology”. The impact of lysosomal diseases on clinical medicine exemplifies this role of pathology of organelles in elucidation of disease today.Another aspect of cell organelles of prime importance is their pathologic alteration by drugs, toxins, hormones and malnutrition. The sensitivity of cell organelles to minute alterations in their environment offers an accurate evaluation of the site of action of drugs in the study of both function and toxicity. Examples of mitochondrial lesions include the effect of DDD on the adrenal cortex, riboflavin deficiency on liver cells, elevated blood ammonia on the neuron and some 8-aminoquinolines on myocardium.

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