scholarly journals Comparative study between fascia lata and temporalis fascia in myringoplasty

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Ayman Ali Abdel Fattah ◽  
Abdel Hay Rashad Elasy ◽  
Ahmed Helmy Hoseini ◽  
Tarek Abdel Rahman Abdel Hafez
Keyword(s):  
Tympanic Membrane ◽  
Good Alternative ◽  
Fascia Lata ◽  
The Body ◽  
Temporalis Fascia ◽  
Fascia Graft ◽  
Fascia Lata Graft ◽  
Group A ◽  
The Mean ◽  
Group B

Abstract Background Repair of a perforated tympanic membrane (myringoplasty) can facilitate normal middle ear function, resist infection, and help re-establish normal hearing. Autogenous graft materials are the most popular graft materials used in myringoplasty because of their easy acceptability by the body. This study is conducted to compare between temporalis fascia graft and fascia lata graft in myringoplasty for patients with tubo-tympanic dry perforation. Results A total of 60 patients with persistent dry tympanic membrane perforation were included in our study during the period from January 2018 to May 2020. Patients underwent myringoplasty with temporalis fascia (30 patients as group A) or fascia lata (30 patients as group B). Patients were scheduled for follow-up visits concerning graft status, ear discharge, and audiograms. The mean postoperative air-bone gap in group A was 17.5 ± 4 after 1 month and 8.6 ± 6.9 after 3 months, while in group B, the mean postoperative air-bone gap was 17.6 ± 4.9 after 1 month and 9.4 ± 7.5 after 3 months. There was 90% success in graft uptake in group A, while there was 80% success in group B. Conclusion Using temporalis fascia is still the best and most trustworthy technique of myringoplasty compared to fascia lata graft. However, fascia lata can be a good alternative to temporalis fascia especially in cases of revision myringoplasty, ears having large perforation, or near-total perforation where the chances of residual perforation are high because of the limited margin of remnant tympanic membrane overlapping the graft.

scholarly journals Endoscopic tympanoplasty using Tutoplast versus conventional microscopic tympanoplasty

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Taha M. Abdelaal ◽  
Ahmed A. Ibrahim
Keyword(s):  
Tympanic Membrane ◽  
Operative Time ◽  
Tympanic Membrane Perforation ◽  
Temporalis Fascia ◽  
Fascia Graft ◽  
Significant Difference ◽  
Membrane Perforation ◽  
Group A ◽  
The Mean ◽  
Group B

Abstract Background Temporalis fascia and perichondrium are still the most successful graft materials for primary microscopic repair of tympanic membrane perforations worldwide with 80% to 90% success rate. However, minimally invasive surgery is becoming standard in many fields and the endoscope has been largely incorporated in ear surgery over the past 10 years. This study aimed to evaluate the success rate of endoscopic transcanal closure of tympanic membrane perforation using Tutoplast® compared with the conventional post auricular approach using homologous temporalis fascia graft. Results Our study was conducted on 50 patients, were equally divided into 2 groups. Group A patients have been operated endoscopic transcanal using the Tutoplast as a graft material. Group B patients have been operated using a temporalis fascia graft through a post-auricular approach. The graft take rate, the pre- and post-operative pure tone audiogram, and operative time were compared in both the groups. The graft uptake rate was 100% in both groups. The mean of ABG showed significant improvement in both groups. In group A, the mean of ABG was 28.2 pre-operatively and became 12.12 post-operatively. In group B, the mean of ABG was 29.72 pre-operatively then became 15.2 post-operatively. Comparing the mean of post-operative ABG between both groups showed statistically significant difference as p value was 0.000496. We found a significant difference of the mean average operative time between both groups as the mean average time for group A was 48.08 min compared to 69.4 min for group B with p value 0.049772295. Conclusions Endoscopic closure of tympanic membrane perforation using Tutoplast is successful short-time procedure avoiding the postauricular or endaural incisions with shorter operative time.

scholarly journals A comparative study of hearing outcome in patients undergoing type 1 tympanoplasty using temporalis fascia versus sliced tragal cartilage

2021 ◽  
Vol 7 (2) ◽  
pp. 258
Author(s):  
Vinod Shinde ◽  
Tejal Sonar ◽  
Shikha Shah ◽  
Ashutosh Kumar ◽  
Anuja Satav
Keyword(s):  
Tympanic Membrane ◽  
Chronic Otitis Media ◽  
P Value ◽  
Temporalis Fascia ◽  
Duration Of Symptoms ◽  
Type 1 Tympanoplasty ◽  
Fascia Graft ◽  
Group A ◽  
The Mean

<p class="abstract"><strong>Background:</strong> A tympanoplasty is a surgical procedure to close a tympanic membrane perforation and reconstruct the tympanic membrane and hearing, commonly after chronic otitis media and trauma.</p><p class="abstract"><strong>Methods:</strong> 50 patients were divided into 2 groups and underwent type-1 tympanoplasty using temporalis fascia versus sliced tragal cartilage. The patient was placed in supine position. Antiseptic painting and draping was done. All cases were operated under local anaesthesia. Post aural approach with post aural Wilde’s incision with 15 number blade, the incision was made 5-10 mm posterior to post aural groove. Temporalis fascia graft was harvested. Tragal cartilage, incision was taken over the under surface of the tragus and tragal cartilage was sliced.  </p><p class="abstract"><strong>Results:</strong> The mean duration of symptoms was 12.72 and 15.84 months in group A and B respectively. Reduced hearing was noted in 21 and 24 patients, ear discharge in 21 each and giddiness in 2 and 4 patients respectively in group A and B. The difference was non-significant when the symptoms were evaluated. Improvement in AB gap was significantly better in group B with a p value of 0.042. The mean improvement was 14.2 dB and 17 dB respectively.</p><p class="abstract"><strong>Conclusions:</strong> Type-1 tympanoplasty using the sliced tragal cartilage may be associated with better improvement in AB gap and can be regularly employed compared to temporalis fascia method.</p>

scholarly journals PREVALENCE OF HEPATIC STEATOSIS AMONG CHILDREN AND ADOLESCENTS WITH CYSTIC FIBROSIS AND ITS ASSOCIATION WITH NUTRITIONAL STATUS

2019 ◽  
Vol 37 (4) ◽  
pp. 435-441
Author(s):  
Amanda Oliva Gobato ◽  
Ana Carolina Junqueira Vasques ◽  
Antonio Fernando Ribeiro ◽  
Roberto Massao Yamada ◽  
Gabriel Hessel
Keyword(s):  
Cystic Fibrosis ◽  
Nutritional Status ◽  
Children And Adolescents ◽  
Hepatic Steatosis ◽  
Statistical Tests ◽  
The Body ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B

ABSTRACT Objective: To determine the prevalence of hepatic steatosis (HS) in children and adolescents with cystic fibrosis (CF) and associate it with nutritional status. Methods: Cross-sectional study with children and adolescents with CF diagnosis. Weight and height were used to calculate the body mass index (BMI) and subsequent classification of the nutritional status. The midarm circumference (MAC), triceps skinfold thickness (TSF) and midarm muscle circumference (MAMC) were used to evaluate body composition. Abdominal ultrasonography was performed for diagnosis of HS. The statistical tests used were Student’s t test, Mann-Whitney test and chi-square test with significance level of 5%. Results: 50 patients with CF were evaluated, 18 (36%) were diagnosed with HS (Group A) and 32 (64%) without HS (Group B). The mean age of Group A was 13,2±4,9 years old and Group B 11,7±4,9; for BMI, the value for Group A was 18,0±4,1 and Group B was 15,7±3,8; the TSF of Group A was 8,4±3,5 mm and Group B was 7,0±2,5 mm. For these variables, there was no significant difference between the groups. The mean of MAC and MAMC differed significantly between the groups, being higher in the HS group, with p values of 0,047 and 0,043. Conclusions: The frequency of HS in patients with CF is high and it is not related to malnutrition, according to the parameters of BMI, TSF and MAMC. The values of MAC and MAMC indicated a greater reserve of muscle mass in patients with HS.

scholarly journals Outcome of Myringoplasty with Temporalis Fascia and Perichondrial-Cartilage Composite Graft in High Risk Perforations

2019 ◽  
Vol 21 (1) ◽  
pp. 60-64
Author(s):  
Anup Dhungana ◽  
RR Joshi ◽  
AS Rijal ◽  
KK Shrestha ◽  
S Maharjan
Keyword(s):  
High Risk ◽  
Tympanic Membrane ◽  
Uptake Rate ◽  
Pure Tone Audiometry ◽  
Composite Graft ◽  
Temporalis Fascia ◽  
Fascia Graft ◽  
Significant Difference ◽  
The Mean ◽  
And Cartilage

 The objective of this study was to compare the graft uptake results and postoperative hearing of myringoplasty with temporalis fascia and cartilage-perichondrial composite graft in high risk perforations. Patients of age 13 years and above with diagnosis of chronic otitis media – mucosal type with high risk perforation that is >50% perforation of tympanic membrane, revision cases, absent/ eroded handle of malleus, oedematous/unhealthy middle ear mucosa and marginal involvement cases were included for myringoplasty. Pure Tone Audiometry was done within 1 week before surgery. 80 cases were included for myringoplasty which were randomly allocated by lottery method with 40 cases each in temporalis fascia group and cartilage perichondrial composite graft group. Graft uptake results were assessed after 6 weeks and postoperative hearing was evaluated and compared within and between the groups. Graft uptake rate in temporalis fascia group and cartilage perichondrial composite graft group was 90% and 92.5%, respectively with no significance difference in the graft uptake rate (p = 0.692) between the groups. The mean pre and post-operative air bone gap in temporalis fascia group and cartilage perichondrial composite group were 30.69dB±10.19,16.36±8.37dB and 33.73±8.07dB, 20.76±9.47dB, respectively with highly significant difference in both groups (p < 0.001) showing improvement in the hearing after surgery in both groups. The mean air bone gain were 14.33dB and 12.97dB in temporalis fascia and cartilage perichondrial composite group respectively with no significant difference between the groups (p=0.469). The graft uptake rate and hearing results after cartilage perichondrial composite graft are comparable to those of temporalis fascia graft. Furthermore, the cartilage perichondrial composite graft is more rigid and thick so it is more resistant than fascia to anatomic deformation and necrosis. Therefore, we recommend the use of cartilage perichondrial composite graft for tympanic membrane reconstruction in high risk perforation without concern about affecting audiometric results.

scholarly journals Effects of Probiotics Supplementation on Growth Performance and Certain Haemato-biochemical Parameters in Broiler Chickens

1970 ◽  
Vol 2 (1) ◽  
pp. 39-43 ◽  
Author(s):  
MW Islam ◽  
MM Rahman ◽  
SML Kabir ◽  
SM Kamruzzaman ◽  
MN Islam
Keyword(s):  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Live Weight ◽  
The Body ◽  
Mean Values ◽  
Growth Performances ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Key Words Probiotics

The study was carried out to know the effects of probiotics (Protexin® Boost) supplementation on growth performances and haemato-biochemical parameters of "Shaver Star Bro" broiler chickens during the period from September to October 2003. A total of 20, day-old broiler chickens were randomly assigned into four equal groups (n = 5) as A, B, C and D. Group A was considered as control fed with commercial ration while group B, C and D were fed with commercial ration with the addition of 1 g, 2 g and 3 g probiotics / 10 litres drinking water respectively up to 35 days of age. The results showed that the body weight gains corresponding to the different treatments were differed significantly (p < 0.01) at the 1st, 2nd, 3rd, 4th and 5th weeks of age. The meat yield characteristics corresponding to the different treatments did not differ significantly (p > 0.05) whereas bursa weight differed significantly (p < 0.05) among the different groups. The mean values of Hb, PCV and ESR corresponding to the different treatments were significantly (p < 0.01) differ. Triglycerides, HDL, LDL, SGPT and SGOT values corresponding to the different treatments were also differed significantly (p < 0.01). The findings suggest that supplementation of probiotics has significant effects on live weight gain and haemato-biochemical parameters of broiler chickens. Key words: Probiotics; effects; growth; haemato-biochemical parameters; broiler chickens doi: 10.3329/bjvm.v2i1.1933 Bangl. J. Vet. Med. (2004). 2 (1) : 39-43

scholarly journals Comparative study of temporalis fascia graft versus cartilage shield tympanoplasty

2018 ◽  
Vol 4 (4) ◽  
pp. 951
Author(s):  
Gaurav Chhabra ◽  
Amresh K. Saxena ◽  
Sanjay Kumar
Keyword(s):  
Comparative Study ◽  
Uptake Rate ◽  
Graft Material ◽  
Temporalis Fascia ◽  
Fascia Graft ◽  
Uptake Rates ◽  
Group A ◽  
Subtotal Perforation ◽  
Group B ◽  
The Comparative Study

<p class="abstract"><strong>Background:</strong> The objective of the study was to demonstrate the comparative study in terms of graft uptake rate &amp; hearing gain between cartilage shield tympanoplasty and temporalis fascia tympanoplasty in patients with moderate/ large/subtotal perforation.</p><p class="abstract"><strong>Methods:</strong> Cartilage shield tympanoplasty and temporalis fascia tympanoplasty were conducted in Group A and Group B, respectively, each containing 30 patients with moderate/large/subtotal perforations. Pure tone audiogram (PTA) was performed preoperatively and at postoperative visit i.e. at 12<sup>th</sup> month, a greater than 10-dB closure of air bone gap (ABG) was considered significant.  </p><p class="abstract"><strong>Results:</strong> The graft uptake rates were 93.33% and 86.67% in Group A and Group B, respectively, at the end of 10th week. In total, 90% in Group A and 88% in Group B had significant improvement in hearing (ABG ≥10 dB) at 12th week of surgery.</p><p class="abstract"><strong>Conclusions:</strong> Conchal cartilage is a possible graft material for cartilage shield tympanoplasty, especially in moderate, large &amp; subtotal perforation, as it is showed superior autograft as compared to temporalis fascia, not only because of better graft uptake rate and less partial failure but also due to the comparable hearing improvement in terms of mean AB gap in both types of graft materials.</p>

scholarly journals Comparative Evaluation of Efficacy Between Topical Calcipotriol Used Along With Topical Clobetasol And Topical Clobetasol Monotherapy In Treatment Of Alopecia Areata: A Randomised Clinical Trial

2021 ◽  
Author(s):  
MohanLal Gupta ◽  
Shivangna Singh ◽  
Bushra Hasan Khan
Keyword(s):  
Vitamin D ◽  
Alopecia Areata ◽  
The Body ◽  
Mean Values ◽  
Affected Area ◽  
Vitamin D Receptors ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Vitamin D Analogue

Introduction: Alopecia Areata (AA) is a hair disorder characterised by non-scarring, patchy loss of hair from scalp and other parts of the body. For the treatment of AA, topical steroid is one of the first line therapeutic options. Topical vitamin D analogue Calcipotriol has immunomodulatory action. Vitamin D receptors (VDR) are present in the hair follicles,therefore for treatment of AA topical vitamin D analogue Calcipotriol can be considered. Aim: To comparatively evaluate the role in terms of efficacy of topical vitamin D analogue Calcipotriol when used along with topical Clobetasol in comparison to topical Clobetasol used alone for AA treatment. Materials and Methods: In this randomised, open label, clinical study, sixty patients (age 20-32 years) diagnosed with AA were randomly assigned into two groups, thirty patients in each from Sept 2019 to Feb 2020. Topical Clobetasol (0.05%) was applied on the affected area twice a day for 24 weeks by Group A patients. While both topical Clobetasol (0.05%) and topical Calcipotriol (0.005%) was applied on the affected area twice daily for 24 weeks by Group B patients. Parametery like Age, Serum Hydroxy Vitamin D (25(OH)D) and SALT Score were mesured at baseline. At regular intervals of time (i.e baseline, 6,12,24 weeks), SALT (Severity Of Alopecia Tool) score was evaluated. Mean values of the data were evaluated using student's t-test and chi-square test based on whether the data was quantitative or qualitative in nature respectively. p<0.05 was considered statistically significant. Results: With respect to age and gender distribution both the groups were comparable (p>0.05). For patients of group A and group B the mean values of SALT score at baseline were 10.45±5.25 and 9.85±4.95, respectively (p=0.65). In patients of Group A and Group B towards the end of 24 weeks the mean values of SALT score decreased to 5.98±4.32 (p=0.0007) and 3.66±3.53 (p=0.0001), with a greater decrease in SALT score seen in Group B (p=0.05) i.e., the group in which patients were treated with topical calcipotriol 0.005% along with topical Clobetasol 0.05%. Conclusion: Topical calcipotriol 0.005% lotion used along with topical Clobetasol 0.05% lotion had higher efficacy than topical Clobetasol 0.05% lotion used alone, in the treatment of AA.

scholarly journals A prospective study of insulin resistance among infertile women with polycystic ovarian syndrome

2018 ◽  
Vol 7 (9) ◽  
pp. 3786
Author(s):  
M. Smitha ◽  
S. Jyothi ◽  
Anand Acharya
Keyword(s):  
Insulin Resistance ◽  
Mean Value ◽  
The Body ◽  
P Value ◽  
Infertile Women ◽  
Androgen Synthesis ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Infertile Patients

Background: Insulin plays a key role in producing hyperandronism and suppression of insulin secretion in women with PCOS is associated with decreased cytochrome P450c17α. cytochrome P450c17α is a bifunctional enzyme present in ovary is a key enzyme for androgen synthesis. Various studies have been conducted regarding association of insulin resistance with PCOS in infertile patients but there is no study is available about this in our area. So we have designed this study to evaluate insulin resistance in infertile patients with PCOS in rural Andhra Pradesh.Methods: The study population include 180 untreated patients who attended the infertility clinic in outpatient department of obstetrics with infertility due to different cause that include polycystic ovarian disorder also. They have been selected for this study randomly based on inclusion and exclusion criteria.Results: The mean value of glucose insulin ratio was 5.146+2.611 in group A and 8.62 + 5.55 in group B the P value was 0.004909. The mean of LH/FSH ratio was 1.78+0.423 in group A and 1.02 +0.042 in group B. The P value was <0.00001. The mean of HOMA IR was 8.375+ 2.68 in group A and 3.03+ 1.09 in group B, with P value <0.00001. The mean value of QUICKI was 0.2815+ 0.0002875 in group A and 0.347+0.10 in group B with P value <0.00001. Mean serum DHEAS level was 275.59 + 53.48 in infertile patient with PCOS and 208.48 + 36.11 in infertile patients without PCOS. The p value was 0.00012.Conclusions: Based on present study we would like to conclude that the body mass index was high among infertile women with PCOS and a greater number of women presented with acanthosis. There was decrease insulin sensitivity and increase insulin resistance among infertile women with poly cystic ovarian disease, in rural area of Andhra Pradesh and that is not different from the study of other part of world.

scholarly journals Morphological and Histological Study of The Pyramidal Lobe of The Thyroid Gland in Bangladeshi People - A Postmortem Study

1970 ◽  
Vol 7 (2) ◽  
pp. 94-100
Author(s):  
Abu Sadat Mohammad Nurunnabi ◽  
Abu Alim ◽  
Sabiha Mahbub ◽  
Segupta Kishwara ◽  
Manowara Begum ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Histological Study ◽  
Thyroid Tissue ◽  
The Body ◽  
Human Thyroid ◽  
Medical College ◽  
Group A ◽  
Pyramidal Lobe ◽  
The Mean ◽  
Group B

Background: The pyramidal lobe of the thyroid gland is an embryonic remnant of the caudal end of the thyroglossal tract. The pyramidal lobe is formed from normal thyroid tissue. A fibrous band, levator glandulae thyroideae, is found occasionally and extending upwards from the apex of the pyramidal lobe. As all thyroid diseases are found to be present in the pyramidal lobe, the study of the pyramidal lobe bears a great importance. Study design: Cross-sectional descriptive type of study. Place and period of study: Department of Anatomy, Dhaka Medical College, Dhaka from January to December 2008. Materials: The present study was performed on 60 post mortem human thyroid gland (39 male and 21 female) collected from unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. Methods: The samples were divided into three age-groups including Group A (10 -20 years), Group B (21- 50 years) & Group C (>50 years) and the pyramidal lobes were studied both morphologically i.e. position, length, breadth, thickness, its association with levator glandulae thyroideae and histologically including presence of thyroid tissue, percentage proportion of parenchyma and stroma. Results: The pyramidal lobe was found in 25 cases out of 60 (41.67%) and situated more on the left side (56%). The mean±SD length of the pyramidal lobe of the thyroid gland was 10.83±0.75 mm in group A, 12.80±3.05 mm in group B and 11.00±1.41 mm in group C. The mean±SD breadth of the pyramidal lobe was 5.50±1.22 mm in group A, 7.60±2.06 mm in group B and 6.75±0.96 mm in group C. The mean±SD thickness of the pyramidal lobe was 3.00±0.00 mm in group A, 3.27±0.59 mm in group B and 3.00±0.96 mm in group C. The levator glandulae thyroideae was found in 12 cases out of 60 (20%) and extended from the apex of the pyramidal lobe to the body of the hyoid bone. The proportion of the parenchyma increases with advancing age upto 50 years. Key Words: morphology; histology; pyramidal lobe; thyroid gland DOI: 10.3329/bja.v7i2.6095 Bangladesh Journal of Anatomy July 2009, Vol. 7 No. 2 pp. 94-100

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