A Suicidal Family

1981 ◽  
Vol 139 (1) ◽  
pp. 68-69 ◽  
Author(s):  
Khin-Maung-Zaw ◽  
K. M. Zaw
Keyword(s):  
Affective Disorder ◽  
Identical Twins ◽  
Familial Incidence ◽  
Affective Illness ◽  
The Family

The familial incidence of affective illness is well documented. Many studies have shown identical twins to be highly concordant for affective illness (e.g. Price, 1968; Tsuang, 1977). Suicide is strongly linked with affective disorder. However, few cases of both twins committing suicide have been described, and the family reported here, in which several other members also committed suicide by violent means, is thought to be of considerable interest.

Psychosis in Bipolar and Unipolar Affective Illness with Special Reference to Schizo-affective Disorder

1984 ◽  
Vol 145 (3) ◽  
pp. 236-242 ◽  
Author(s):  
George Winokur
Keyword(s):  
Special Reference ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Course Of Illness ◽  
Affective Illness ◽  
Family Histories ◽  
The Family ◽  
History Of ◽  
Motor Abnormalities ◽  
Multiple Episodes

SummaryBipolar and unipolar patients respectively were separated into psychotic and non-psychotic sub-types. The bipolar psychotic patients were more likely to have certain severe symptoms, such as hallucinations and motor abnormalities, than were the unipolar patients, but the family histories of the four sub-groups were identical. The psychotic sub-groups had a different course of illness, in that they were less likely to have had a history of multiple episodes on admission and were more likely to show chronicity for a period of time on discharge. The data are interpreted as being opposed to the concept of a continuum of vulnerability in the affective disorders, and as not favouring either psychotic unipolar or psychotic bipolar illnesses or schizo-affective disorder being considered autonomous. One possible interpretation of the findings is that a trait or propensity to psychosis is transmitted totally independently of the major affective illness, and that this propensity is silent or not observed when the patient is in remission.

Plasma Lithium Levels and Therapeutic Outcome in the Prophylaxis of Affective Disorders: A Retrospective Study

1982 ◽  
Vol 140 (6) ◽  
pp. 619-622 ◽  
Author(s):  
S. P. Sashidharan ◽  
R. J. McGuire ◽  
A. I. M. Glen
Keyword(s):  
Retrospective Study ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Favourable Outcome ◽  
Therapeutic Outcome ◽  
Lithium Therapy ◽  
Affective Illness

SummaryPatients receiving prophylactic lithium therapy for primary affective disorder during a four year period were studied for recurrence of affective illness. Patients who had affective episodes during this period did not differ from those who remained well in age, sex or diagnosis. Those with a favourable outcome had spent significantly less time at serum lithium levels above 0.9 mmol/litre than those who had a recurrence of affective episodes.

Pre-Pubertal Depressive Stupor: A Case Report

1988 ◽  
Vol 153 (5) ◽  
pp. 689-692 ◽  
Author(s):  
J. C. Powell ◽  
W. R. Silveira ◽  
R. Lindsay
Keyword(s):  
Case Report ◽  
Family History ◽  
Affective Disorder ◽  
Dexamethasone Suppression Test ◽  
Clinical State ◽  
Affective Illness ◽  
History Of ◽  
Suppression Test ◽  
Dexamethasone Suppression ◽  
Maternal Side

A case of childhood affective disorder with episodes of depressive stupor in a 13-year-old pre-pubertal boy is described. Changes in the patient's clinical state were accompanied by changes in the dexamethasone suppression test. A family history of affective illness on the maternal side, with phenomenological similarities, is noted.

Cervical arteriovenous anastomosis in one of identical twins

1954 ◽  
Vol 4 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Robert M. Rankin
Keyword(s):  
Physical Violence ◽  
Mental Disease ◽  
Shock Therapy ◽  
Identical Twins ◽  
Arteriovenous Anastomosis ◽  
The Family ◽  
Before And After ◽  
Clinical Diagnoses ◽  
History Of ◽  
Mental Institution

In recent years various surgical procedures have been attempted to improve the cerebral function of mentally retarded or cerebral palsied children. One of these is the anastomosis of the carotid artery and jugular vein in an effort to improve the cerebral blood flow. This has been reported to have some degree of success, but the results are of questionable value because of the necessary lack of suitable controls. In this paper are presented the case histories of such an operation on identical twins, one operated and the second serving as a perfect control.The family history of the twins was significant in that there was a strong history of mental disease on the father's side. Several members of his family had been confined to mental institutions. No clinical diagnoses are known but at least one was known to be a sexual pervert. The father had been in a mental institution before and after the birth of the twins and had received electric shock therapy, with no demonstrable improvement. He also was a sexual pervert. The parents were divorced when the twins were twenty months old. Before and after the divorce the twins and their mother were subjected to physical violence by the father. The twins were said to be extremely fearful of the father. There were no other children, and no other pregnancies.Pregnancy was uneventful. Delivery was at term following a five day labor. Donald, the twin who was subsequently operated, was born first with a birth weight of six pounds, seven ounces. David, born a few minutes later, weighed six pounds, eight ounces.

Associations of affective disorder in patients with inflammatory bowel disease

2011 ◽  
Vol 26 (S2) ◽  
pp. 2220-2220 ◽  
Author(s):  
B.J. Baig ◽  
C.W. Lees ◽  
E.C. Johnstone ◽  
V. James ◽  
J. Satsangi ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Affective Disorder ◽  
Bowel Disease ◽  
Rating Scale ◽  
Depression Scale ◽  
Cross Sectional Study ◽  
Medication History ◽  
Cross Sectional ◽  
Affective Illness ◽  
Inflammatory Bowel

IntroductionInflammatory Bowel Disease (IBD) is associated with co morbid depression and anxiety of up to 42%. Corticosteroids, used commonly in IBD, are known to cause psychiatric side-effects and could be an independent risk factor for affective illness. Recent studies show that depression is also associated with raised CRP and IL6.AimsThis study aims to show which demographic, clinical, medication and immunological factors are predictors of anxiety and depression in IBD.MethodsThe IBD, Steroids and Affective Disorder (ISA) study is a cross-sectional study of IBD patients in Edinburgh, UK. Out patients underwent assessment including Hospital Anxiety Depression Scale (HADS) past psychiatric history, steroid medication history, inflammatory markers, the Medication Adherence Rating Scale (MARS) and Altman Self Rated Mania Scale (ARSM).Results326 patients with Crohns and 256 with Colitis (72% of clinic attendees) were recruited. 251 (43%) patients scored 12 or above on the HADS questionnaire. 45% of patients had previously suffered from affective illness. Patients on Prednisolone and Budesonide scored significantly higher on HADS Depression (p = 0.03 and p = 0.002) as did those who had been on Prednisolone for more than 8 weeks (p = 0.041). Being on prednisolone was not associated with increased Colitis and Crohns activity indices (p = 0.2). HADS scores were measured against other disease and demographic variables.ConclusionAffective illness is common in the IBD population and the prescription and duration of systemic corticosteroids are associated with depression. Biological and disease variables may play an important role in co morbid affective illness in IBD

scholarly journals Quality of Life in Schizophrenia and Bipolar Affective Disorder

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Pratima
Keyword(s):  
Quality Of Life ◽  
Bipolar Disorder ◽  
Affective Disorder ◽  
Expressed Emotion ◽  
Bipolar Affective Disorder ◽  
Poor Quality ◽  
Living Environment ◽  
The Family ◽  
Bipolar Patients

Family caregivers of persons with bipolar disorder and schizophrenia experience high level of burden and compromised quality of life. A considerable amount of burden on the caregivers often leads to display of certain attitudes towards persons with severe mental illness called expressed emotion, which then leads to poor quality of patients as well. Although numerous studies dealing with these issues separately are present, but studies dealing with relationship, using mixed methodology, among these issues are scarce. The aim of the present study was to understand how actually the construct of quality of life in different demographic conditions affect life conditions of schizophrenic and bipolar patients and determining relapse. The present study was designed mainly to assess the quality of life on patients and the families of a particular group of patients namely those with schizophrenia and bipolar disorder. The objectives if the present research were to study: (i) the quality of life of patients with Schizophrenia and Bipolar Affective disorder. (ii) the quality of life of caregivers of patients with Schizophrenia and Bipolar Affective disorder. Patients with disorders such as schizophrenia and bipolar affective disorder are more likely to relapse when there is high expressed emotion present in their living environment. The stress from the remarks and attitudes of the family is overwhelming because they feel like the cause of the problems. The patient then falls into the cycle of relapse. The only way to escape this vortex for the family is to go through therapy together to prevent the relapse. But before that it becomes necessary to understand that what is the reason behind such attitude towards a family member who is mentally ill, what is the cause of burden and what all changes the caregivers’ and the patients’ quality of life come across.

scholarly journals The affective disorder-related burden imposed on the family environment: an overview

2013 ◽  
Vol 47 (4) ◽  
pp. 635-644 ◽  
Author(s):  
Joanna Borowiecka-Kluza ◽  
Magdalena Miernik-Jaeschke ◽  
Rafał Jaeschke ◽  
Marcin Siwek ◽  
Dominika Dudek
Keyword(s):  
Affective Disorder ◽  
Family Environment ◽  
The Family

The Effects of Treatment on Mortality in Affective Illness

1992 ◽  
Vol 6 (2_suppl) ◽  
pp. 312-317 ◽  
Author(s):  
Guy M. Goodwin
Keyword(s):  
Drug Treatment ◽  
Affective Disorder ◽  
Excess Mortality ◽  
Mortality Data ◽  
Adequate Treatment ◽  
Refractory Depression ◽  
Risk Of Death ◽  
Affective Illness ◽  
The Impact

All studies of mortality in patients with a diagnosis of affective illness agree that the death rate is increased. The excess mortality appears primarily to result from suicide; any excess mortality from physical illness, most notably cardiovascular disease, now appears unlikely to be a simple consequence of affective illness. Historical comparisons suggest that acute treatment of affective disorder reduces the immediate risk of death. It is much more difficult to assess the impact of treatment upon the subsequent rates of suicide. This is true of all aspects of the acute and short-term continuation of treatment for an episode of illness, from the need for hospital admission to the choice of drug treatment. Adequate treatment of refractory depression and the possibility that some actions of drugs may increase the risks of suicide are emergent therapeutic issues that are still providing more questions than answers. Prophylaxis should also reduce the risk of suicide. However, although standardized mortality rates, reflecting relative risk, are very high, only ~2% of patients with affective disorder will commit suicide in a follow-up interval of 2 years. Comparison of mortality data for patients on lithium registers with that from lithium clinics shows important reductions in specialized clinics. Indeed, mortality from suicide may actually be lower than expected. It raises the question of whether long-term hospital follow-up by personnel with a specialist interest in drug treatment of major mental illness is safer than a potentially more erratic provision of care in the community. The future issues in the prevention of suicide include whether to treat patients by admission to a hospital in-patient unit or not, whether to treat for at least a year with adequate doses of tricyclic drugs or a selective 5-hydroxytryptamine (5-HT, serotonin) re-uptake inhibitor, and whether to maintain patients with a second episode of affective illness or a prolonged first illness indefinitely with lithium or antidepressants.

Conduct disorder and affective disorder among the offspring of patients with Huntington's Disease

1983 ◽  
Vol 13 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Susan E. Folstein ◽  
Mary Lousie Franz ◽  
Barbara A. Jensen ◽  
Gary A. Chase ◽  
Marshal F. Folstein
Keyword(s):  
Conduct Disorder ◽  
Psychiatric Disorder ◽  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Affective Disorder ◽  
Genetic Counselling ◽  
Early Onset ◽  
Affective Illness ◽  
Hd Gene ◽  
Early Manifestation

SynopsisThe rate of occurrence of conduct disorder and affective illness was studied for a sample of 112 offspring of 34 Huntington's Disease (HD) patients. Psychiatric disorder in the offspring was assessed as a function of: (1) age of the parent at the onset of symptoms of HD; (2) family disorganization; and (3) psychiatric disorder in either parent. The findings indicated an increased frequency of conduct disorder in disrupted families, most especially in those where the HD parent had an early onset of symptoms and the non-HD parent showed psychiatric disorder. Affective disorder in the offspring was most strongly associated with the presence of similar symptoms in the HD parent. Affective disorder, but not conduct disorder, may be an early manifestation of the HD gene. The implication of these findings for genetic counselling is discussed.

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