Psychosis in Bipolar and Unipolar Affective Illness with Special Reference to Schizo-affective Disorder

1984 ◽  
Vol 145 (3) ◽  
pp. 236-242 ◽  
Author(s):  
George Winokur
Keyword(s):  
Special Reference ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Course Of Illness ◽  
Affective Illness ◽  
Family Histories ◽  
The Family ◽  
History Of ◽  
Motor Abnormalities ◽  
Multiple Episodes

SummaryBipolar and unipolar patients respectively were separated into psychotic and non-psychotic sub-types. The bipolar psychotic patients were more likely to have certain severe symptoms, such as hallucinations and motor abnormalities, than were the unipolar patients, but the family histories of the four sub-groups were identical. The psychotic sub-groups had a different course of illness, in that they were less likely to have had a history of multiple episodes on admission and were more likely to show chronicity for a period of time on discharge. The data are interpreted as being opposed to the concept of a continuum of vulnerability in the affective disorders, and as not favouring either psychotic unipolar or psychotic bipolar illnesses or schizo-affective disorder being considered autonomous. One possible interpretation of the findings is that a trait or propensity to psychosis is transmitted totally independently of the major affective illness, and that this propensity is silent or not observed when the patient is in remission.

Schizophrenia and Affective Disorder: Are They Genetically Linked?

1991 ◽  
Vol 159 (2) ◽  
pp. 267-270 ◽  
Author(s):  
Miron Baron ◽  
Rhoda S. Gruen
Keyword(s):  
Family History ◽  
Major Depression ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Nuclear Families ◽  
Affective Illness ◽  
Increased Risk ◽  
History Of ◽  
Spectrum Disorders ◽  
The Relationship

The relationship between schizophrenic ‘spectrum’ disorders and affective illness was studied in the nuclear families of 90 chronic schizophrenic probands. An increased risk of schizophrenia and related disorders was demonstrated among the first-degree relatives of probands with a family history of major affective disorders. Conversely, relatives of probands with a family history of schizophrenic ‘spectrum’ disorders were at a greater risk of affective illness (major depression) than relatives of probands with no family history. These results lend support to the notion that a subset of affective disorders is associated with the liability to schizophrenia.

Plasma Lithium Levels and Therapeutic Outcome in the Prophylaxis of Affective Disorders: A Retrospective Study

1982 ◽  
Vol 140 (6) ◽  
pp. 619-622 ◽  
Author(s):  
S. P. Sashidharan ◽  
R. J. McGuire ◽  
A. I. M. Glen
Keyword(s):  
Retrospective Study ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Favourable Outcome ◽  
Therapeutic Outcome ◽  
Lithium Therapy ◽  
Affective Illness

SummaryPatients receiving prophylactic lithium therapy for primary affective disorder during a four year period were studied for recurrence of affective illness. Patients who had affective episodes during this period did not differ from those who remained well in age, sex or diagnosis. Those with a favourable outcome had spent significantly less time at serum lithium levels above 0.9 mmol/litre than those who had a recurrence of affective episodes.

Everyday creativity and bipolar and unipolar affective disorder: preliminary study of personal and family history

1992 ◽  
Vol 7 (2) ◽  
pp. 49-52 ◽  
Author(s):  
R Richards ◽  
DK Kinney ◽  
H Daniels ◽  
K Linkins
Keyword(s):  
Bipolar Disorder ◽  
Family History ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Bipolar Disorders ◽  
Data Support ◽  
History Of ◽  
Preliminary Study ◽  
Everyday Creativity ◽  
Underlying Mechanisms

SummaryPreliminary new data support the enhancement of ‘everyday’ creativity among those persons with bipolar disorders who manifest milder rather than more severe mood elevations, and among certain individuals who are likely to carry bipolar liability but themselves show no clinical mood elevations – in this case, unipolar depressives with a family history of bipolar disorder, when compared with depressives lacking this history. Creativity was assessed using the lifetime creativity scales (Richards el al, 1988). Underlying mechanisms may be multifactorial and complex. Results suggest that both personal and family history should be considered when making predictions concerning creativity and affective disorders.

Pre-Pubertal Depressive Stupor: A Case Report

1988 ◽  
Vol 153 (5) ◽  
pp. 689-692 ◽  
Author(s):  
J. C. Powell ◽  
W. R. Silveira ◽  
R. Lindsay
Keyword(s):  
Case Report ◽  
Family History ◽  
Affective Disorder ◽  
Dexamethasone Suppression Test ◽  
Clinical State ◽  
Affective Illness ◽  
History Of ◽  
Suppression Test ◽  
Dexamethasone Suppression ◽  
Maternal Side

A case of childhood affective disorder with episodes of depressive stupor in a 13-year-old pre-pubertal boy is described. Changes in the patient's clinical state were accompanied by changes in the dexamethasone suppression test. A family history of affective illness on the maternal side, with phenomenological similarities, is noted.

Diagnosing Affective Disorder in Adolescents: The Use of the Schedule for Affective Disorders and Schizophrenia

1985 ◽  
Vol 30 (8) ◽  
pp. 605-608 ◽  
Author(s):  
S.P. Kutcher ◽  
G. Yanchyshyn ◽  
Carole Cohen
Keyword(s):  
Affective Disorder ◽  
Affective Disorders ◽  
Depressive Disorders ◽  
Past History ◽  
Structured Interview ◽  
Good Measure ◽  
Traditional Assessment ◽  
Assessment Period ◽  
History Of

The Schedule for Affective Disorders and Schizophrenia was administered to 42 consecutively hospitalized psychiatrically disturbed adolescents. The SADS proved to be a good measure of current affective disorder and also identified a large number of adolescents with a positive past history of affective disorder. These patients had not been so identified by traditional assessment means. The use of a semi-structured interview is to be encouraged in the assessment period of psychiatrically disturbed adolescents and in further research at attempts to define the parameters of depressive disorders occurring in adolescents.

A Suicidal Family

1981 ◽  
Vol 139 (1) ◽  
pp. 68-69 ◽  
Author(s):  
Khin-Maung-Zaw ◽  
K. M. Zaw
Keyword(s):  
Affective Disorder ◽  
Identical Twins ◽  
Familial Incidence ◽  
Affective Illness ◽  
The Family

The familial incidence of affective illness is well documented. Many studies have shown identical twins to be highly concordant for affective illness (e.g. Price, 1968; Tsuang, 1977). Suicide is strongly linked with affective disorder. However, few cases of both twins committing suicide have been described, and the family reported here, in which several other members also committed suicide by violent means, is thought to be of considerable interest.

Scores on Neuroticism Pathology, Mood, and Rorschach and Diagnosis of Affective Disorder

1977 ◽  
Vol 40 (3_suppl) ◽  
pp. 1135-1141 ◽  
Author(s):  
Donald S. Schaeffer
Keyword(s):  
Social Competence ◽  
Affective Disorder ◽  
Affective Disorders ◽  
The Social ◽  
History Of ◽  
Neuroticism Scale ◽  
Speech Content

Patients in an affective disorders clinic diagnosed unipolar ( n = 13), bipolar ( n = 10), or schizo-affective ( n = 7) disorder were given a Maudsley Neuroticism Scale, a Rorschach, and a form interview. Mood over the course of the procedure was assessed and speech content measured. Diagnostic groups differed on background measures of social competence, schizo-affectives being poorer than bipolar and unipolar subjects. Rorschach pathognomic verbalization scores for schizo-affective and bipolar subjects were poorer than for unipolar subjects. Rorschach form definiteness for schizo-affectives was poorer than for bipolar and unipolar subjects. Neuroticism scores did not discriminate diagnostic groups but correlated with mood ratings. History of mania was associated with symbolic bizarreness, resembling schizo-affective disorder. However, the social competence and perceptual maturity of subjects with manic histories did not differ from those without.

Mania in the elderly

1989 ◽  
Vol 155 (2) ◽  
pp. 220-224 ◽  
Author(s):  
Kit Stone
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Affective Disorders ◽  
Age Of Onset ◽  
The Elderly ◽  
Prior History ◽  
Lithium Toxicity ◽  
Affective Illness ◽  
History Of

A retrospective study of 92 patients admitted with mania, aged over 65 years of age, found that 26% had no prior history of affective illness; 30% had previously only experienced depression, and half of these had at least three episodes of depression before the first manic illness. Patients with a family history of affective disorders had a significantly earlier age of onset of illness. There was evidence of cerebral organic impairment in 24% of the patients, and this group had a significantly later age of onset of illness. Prognosis was good, with only 8% still in hospital at six months. Half of the patients were started on lithium prophylaxis, but this did not significantly alter the number of readmissions. A quarter of those started on lithium developed evidence of lithium toxicity.

scholarly journals Use of social media and online dating among individuals with a history of affective disorder

2020 ◽  
pp. 1-12
Author(s):  
Klara F. K. Rydahl ◽  
René B. K. Brund ◽  
Clara R. Medici ◽  
Vibeke Hansen ◽  
Krista N. Straarup ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Social Media ◽  
Affective Disorder ◽  
Affective Disorders ◽  
Odds Ratio ◽  
Online Dating ◽  
Unipolar Depression ◽  
History Of ◽  
Use Of Social Media ◽  
Depressive Episodes

Abstract Objectives: To investigate how individuals with a history of affective disorder use and perceive their use of social media and online dating. Methods: A questionnaire focusing on affective disorders and the use of social media and online dating was handed out to outpatients from unipolar depression and bipolar disorder clinics and general practice patients with or without a history of affective disorders (latter as controls). The association between affective disorders and use of social media and online dating was analysed using linear/logistic regression. Results: A total of 194 individuals with a history of unipolar depression, 124 individuals with a history of bipolar disorder and 196 controls were included in the analysis. Having a history of unipolar depression or bipolar disorder was not associated with the time spent on social media compared with controls. Using the controls as reference, having a history bipolar disorder was associated with use of online dating (adjusted odds ratio: 2.2 (95% CI: 1.3; 3.7)). The use of social media and online dating had a mood-congruent pattern with decreased and more passive use during depressive episodes, and increased and more active use during hypomanic/manic episodes. Among the respondents with a history of affective disorder, 51% reported that social media use had an aggravating effect on symptoms during mood episodes, while 10% reported a beneficial effect. For online dating, the equivalent proportions were 49% (aggravation) and 20% (benefit), respectively. Conclusion: The use of social media and online dating seems related to symptom deterioration among individuals with affective disorder.

Sign in / Sign up

Export Citation Format

Share Document