Significance of Extreme Temperament in Infancy for Clinical Status in Preschool Years

1989 ◽  
Vol 154 (4) ◽  
pp. 544-551 ◽  
Author(s):  
Michel Maziade ◽  
Jacques Thivierge ◽  
Robert Côté ◽  
Pierrette Boutin ◽  
Hugues Bernier

Few, if any, of children's behavioural or cognitive characteristics assessed in the first years of life demonstrate stability until later childhood; early characteristics have so far failed to show an association with future psychopathology. This longitudinal study, from 4–8 months to 4.7 years old, focused on stability and change of extreme temperamental traits in groups of infants subselected from a large birth cohort. Persistent extreme temperament at four and eight months old did not increase stability of temperament to four years of age, relative to other children in the whole population. Sizeable change occurred, and the environmental parameters associated with negative temperamental change did not seem to be the same as those related to positive change. Boys with extreme scores were more stable, while girls appeared more prone to positive change. It is hypothesised that the direction of temperamental change in the first years could be more meaningful for long-term prediction of disorders than any one assessment of temperament taken at any one year.

Author(s):  
Joannes W. Renes ◽  
Dominique F. Maciejewski ◽  
Eline J. Regeer ◽  
Adriaan W. Hoogendoorn ◽  
Willem A. Nolen ◽  
...  

1976 ◽  
Vol 129 (3) ◽  
pp. 252-260 ◽  
Author(s):  
Myrna M. Weissman ◽  
Stanislav V. Kasl

SummaryThis paper reports on the clinical status, help-seeking and subsequent treatment experiences of 150 women one year after they had completed out-patient maintenance treatment by amitriptyline and/or psychotherapy for a depressive episode.While the majority of patients were asymptomatic at follow-up, a substantial minority had a return of acute symptoms and 2 per cent made minor suicide attempts during the year. Admission to hospital was rare. However, only 30 per cent of the patients did not seek any treatment during the year and the majority received some psychotropic medication.The findings support the long-term need for prompt access to treatment by patients who have recovered from an acute depression.


2021 ◽  
Vol 100 (2) ◽  
pp. 17-21
Author(s):  
A.G. Rumyantsev ◽  

The study of the immune response to SARS-CoV-2 is crucial for the prognosis and control of coronavirus infection, diagnosis and formation of individual and population immunity, the development of indications and evaluation of the effectiveness of vaccinations, and, ultimately, the scientific prediction of the course of a pandemic. One year after the infection debuted in numerous immunological studies in COVID-19 patients, kinetics, duration and evolution of immune memory in humans due to infection are not well predictable, as data obtained represent the initial effector phase of the immune response, and the responses after recovery from infection cannot be used for long-term prediction. The paper presents an analysis of the results of studies of immune response and immune memory to SARS-CoV-2, including all three branches of adaptive immunity: immunoglobulins, memory B-cells, CD8+ and CD4+ T-cells in sick and cured patients in the dynamic period of 6–8 months after the onset of the disease.


2014 ◽  
Vol 38 (5) ◽  
pp. 453-460 ◽  
Author(s):  
Jens B. Asendorpf ◽  
Rens van de Schoot ◽  
Jaap J. A. Denissen ◽  
Roos Hutteman

Most longitudinal studies are plagued by drop-out related to variables at earlier assessments (systematic attrition). Although systematic attrition is often analysed in longitudinal studies, surprisingly few researchers attempt to reduce biases due to systematic attrition, even though this is possible and nowadays technically easy. This is particularly true for studies of stability and the long-term prediction of developmental outcomes. We provide guidelines how to reduce biases in such cases particularly with multiple imputation. Following these guidelines does not require advanced statistical knowledge or special software. We illustrate these guidelines and the importance of reducing biases due to selective attrition with a 25-year longitudinal study on the long-term prediction of aggressiveness and delinquency.


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