scholarly journals Simultaneous Testing of Grouped Hypotheses: Finding Needles in Multiple Haystacks

2009 ◽  
Vol 104 (488) ◽  
pp. 1467-1481 ◽  
Author(s):  
T. Tony Cai ◽  
Wenguang Sun
2020 ◽  
Vol 3 (1) ◽  
pp. 45-55
Author(s):  
Larassanti Eka Putri ◽  
K. Bagus Wardianto ◽  
Ghia Subagia

ABSTRAK Penelitian ini bertujuan untuk mengetahui pengaruh kesadaran logo halal dan iklan media sosial Instagram terhadap keputusan pembelian produk kosmetik.  Jenis penelitian yang digunakan adalah explanatory research dengan pendekatan kuantitatif. Populasi dalam penelitian ini adalah konsumen wanita yang menggunakan kosmetik Wardah di Bandar Lampung, dengan sampel sebanyak 100 responden. Teknik pengambilan sampel menggunakan purposive sampling. Data dikumpulkan menggunakan kuisioner, dan dianalisis menggunakan analisis regresi linier berganda. Hasil penelitian ini menunjukkan bahwa kesadaran logo halal, dan iklan media sosial Instagram berpengaruh signifikan secara parsial maupun silmultan terhadap keputusan pembelian kosmetik. Kehalalan dapat menjadi branding yang semakin kuat, jika didukung dengan promosi melalui media sosial, yang mampu menjangkau segmentasi pasar yang lebih luas terhadap produk lokal.   ABSTRACT This study aims to determine the effect of Awareness of the Halal Logo and Instagram Social Media Ads on Wardah Cosmetics Purchasing Decisions. This type of research used in this research is explanatory research with a quantitative approach. The population in this study is female consumers who use Wardah cosmetics in Bandar Lampung. The sampling technique uses purposive sampling with a sample of 100 respondents. The data was obtained from a questionnaire using a Likert scale. The results of this study explain that Awareness of the Halal Logo, and Instagram Social Media Ads significantly influence Wardah Cosmetics Purchasing Decisions. Simultaneous testing results showed that Halal Logo Awareness and Instagram Social Media Ads had a significant effect on Wardah Cosmetics Purchasing Decisions.


Author(s):  
C. Daniel Batson

The first new possibility was that empathic concern simultaneously produces all five egoistic motives we have considered. This possibility raised three distinct but related concerns: (a) The search for altruism has focused on testing egoistic alternatives, not on testing the altruism hypothesis directly. (b) The egoistic alternatives have been tested one at a time. (c) The egoistic alternatives should be examined simultaneously, as a gang. Concerning the first concern, the reason for focusing on the egoistic alternatives was examined and found justified. Second, testing the egoistic motives one at a time wasn’t a problem because when examining each new egoistic motive, care was taken to make sure that previously dismissed motives couldn’t account for the new results predicted by the empathy–altruism hypothesis. Regarding simultaneous testing, several later experiments had addressed all five egoistic motives and failed to support the all-at-once alternative. The gang idea was dismissed.


Author(s):  
Nina Reiners ◽  
Carolin Schnurra ◽  
Henning Trawinski ◽  
Judith Kannenberg ◽  
Thomas Hermsdorf ◽  
...  

AbstractSARS CoV-2 antibody assays measure antibodies against the viral nucleoprotein (NP) or spike protein. The study examined if testing of antibodies against both antigens increases the diagnostic sensitivity. Sera (N=98) from infected individuals were tested with ELISAs based on the NP, receptor-binding domain (RBD), or both proteins. The AUROCs were 0.958 (NP), 0.991 (RBD), and 0.992 (NP/RBD). The RBD- and NP/RBD-based ELISAs showed better performance than the NP-based assay. Simultaneous testing for antibodies against NP and RBD increased the number of true and false positives. If maximum diagnostic sensitivity is required, the NP/RBD-based ELISA is preferable. Otherwise, the RBD-based ELISA is sufficient.


2014 ◽  
Vol 6 (3) ◽  
pp. 033142 ◽  
Author(s):  
I. Visa ◽  
M. Comsit ◽  
M. D. Moldovan ◽  
A. Duta
Keyword(s):  

2013 ◽  
Vol 6 (1) ◽  
pp. 31-41 ◽  
Author(s):  
H.U. Aamot ◽  
I.S. Hofgaard ◽  
G. Brodal ◽  
O. Elen ◽  
B. Holen ◽  
...  

The aim of this study was to evaluate the performance and usefulness of three rapid test kits for analysis of HT-2 and T-2 toxins (HT-2 and T-2), two of the most potent trichothecenes commonly found in European oats. Concentrations of these two toxins combined (HT-2+T-2) were analysed in naturally contaminated oat samples (n=68) using the following test kits: Ridascreen® FAST T-2 Toxin (‘Fast ELISA’), DRAFT Ridascreen® HT-2/T-2 (‘Standard ELISA’, not commercially available), and the lateral flow device ROSA® HT-2-T-2 (‘Rosa LFD’). Mycotoxin analysis by LC-MS/MS was used as a reference method. Rosa LFD offered the best reliability, achieving detection that was stable across toxin levels, whereas detection by both ELISA kits differed significantly among toxin levels (P<0.01). The kits were also evaluated regarding agreement with the reference method (measured as Cohen's kappa) at a HT-2+T-2 concentration of 1000 μg/kg in naturally contaminated oats. Agreement was greatest for Rosa LFD (89.2%), intermediate for Standard ELISA (66.8%), and lowest for Fast ELISA (62.2%). Rosa LFD showed cross-reaction of 100% with both T-2 and HT-2. For the ELISA kits, cross-reactions were 100% with T-2 but below 100% with HT-2. Therefore, to estimate the sum of HT-2 and T-2 in an oat sample, it was necessary to re-calculate the data from both ELISA kits according to the known cross-reaction of each kit with HT-2 and the concentration ratio of HT-2 to T-2 in Norwegian oats. Rosa LFD had the highest correlation with LC-MS/MS (R2=0.94), and the corresponding R2 values for Fast and Standard ELISA were 0.61 and 0.83, respectively. Rosa LFD was well suited for on-site detection. Standard ELISA allows simultaneous testing of several samples that are useful for centralised laboratories.


2000 ◽  
Vol 25 (1) ◽  
pp. 60-83 ◽  
Author(s):  
Yoav Benjamini ◽  
Yosef Hochberg

A new approach to problems of multiple significance testing was presented in Benjamini and Hochberg (1995), which calls for controlling the expected ratio of the number of erroneous rejections to the number of rejections–the False Discovery Rate (FDR). The procedure given there was shown to control the FDR for independent test statistics. When some of the hypotheses are in fact false, that procedure is too conservative. We present here an adaptive procedure, where the number of true null hypotheses is estimated first as in Hochberg and Benjamini (1990), and this estimate is used in the procedure of Benjamini and Hochberg (1995). The result is still a simple stepwise procedure, to which we also give a graphical companion. The new procedure is used in several examples drawn from educational and behavioral studies, addressing problems in multi-center studies, subset analysis and meta-analysis. The examples vary in the number of hypotheses tested, and the implication of the new procedure on the conclusions. In a large simulation study of independent test statistics the adaptive procedure is shown to control the FDR and have substantially better power than the previously suggested FDR controlling method, which by itself is more powerful than the traditional family wise error-rate controlling methods. In cases where most of the tested hypotheses are far from being true there is hardly any penalty due to the simultaneous testing of many hypotheses.


1991 ◽  
Vol 54 (5) ◽  
pp. 349-353 ◽  
Author(s):  
AMECHI OKEREKE ◽  
THOMAS J. MONTVILLE

Twenty-three strains of lactic acid bacteria were tested by deferred antagonism methods for bacteriocin-like activity against types A and B spores from 11 proteolytic and nonproteolytic Clostridium botulinum strains. Pediococcus pentosaceus ATCC 43200, Pediococcus pentosaceus ATCC 43201, Lactococcus lactis subsp. lactis ATCC 11454, Lactobacillus acidophilus N2, Lactobacillus plantarum Lb75, Lactobacillus plantarum Lb592, and Lactobacillus plantarum BN exhibited bacteriocin-like inhibition of all C. botulinum strains tested. By excluding inhibition due to hydrogen peroxide, acid, and lytic phage and confirming their proteinaceous nature, the inhibitors were confirmed as bacteriocins. The minimum inhibitory cell concentrations (MICC) required to produce 1 mm radius inhibition zones were determined by direct antagonism testing. Only strains 43200, 43201, 11454, and N2 were inhibitory when cultured simultaneously with the botulinal spores. The MICCs of strains antagonistic to C. botulinum spores by simultaneous testing ranged between 1.6 × 105and 4.7 × 107CFU/ml. Based on the MICCs, P. pentosaceus 43200 was most inhibitory to C. botulinum.


2013 ◽  
Vol 8 (4) ◽  
Author(s):  
Rima D. Mangundap ◽  
Herman Karamoy ◽  
Stanly Alexander

Companies as a form of organization in general has a specific goal to be achieved in an effort to meet the interests of its members. Success in achieving the company's goal is performance management. Performance appraisal or performance of a company is measured because it can be used as the basis for decision making both internally and eksternal.Tujuan of this study was to determine Is asset structure, debt ratios, and capital structure affect the financial performance of companies either simultaneously or partially. The method used in this study is the linear regression equation berganda.Dalam simultaneous testing result that financial factors have a significant influence on the financial performance of the company. This is evidenced by calculated F value is greater than the value of F table  and significant values significantly smaller than the size. Subsequently the partial test of the three variables tested only a capital structure that has a significant influence on the financial performance of the company.


2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Ahmad Syifa ◽  
Budi Heryanto ◽  
Sri Rochani

The purpose of this study is as follows: To determine the effect of testimonials on purchase intention On the Product LA Florist, to identify the Influence of eWOM ( Electronic Word Of Mouth ) towards the Purchase Intention on the Product LA Florist, to identify the Influence of Testimonials And eWOM ( Electronic Word Of Mouth ) toward the Purchase Intention on the Product LA Florist. Population in this research is on consumer product LA Florist that totaled 56. The sample used is the whole of the total population. Methods of data collection using questionnaire, observation, interview, and literature Study. Partial test results showed that the influential and significant between the variables of testimonials on Purchase Intention as evidenced by the significant value of 0.000 which is smaller than 0.05 (0.000 < 0,05). Partial test results showed that the influential and significant between the variables of eWOM towards Purchase Intention as evidenced by the significant value of 0.005 which is smaller than 0,05 (0,005 < 0,05). Based on the results of the calculation of the obtained significant value is 0.000. This shows that the significant value of F test variable testimonials and eWOM <0.05, which means that the result of simultaneous testing are testimonial and eWOM influence thePurchase Intention Tujuan penelitian ini adalah sebagai berikut: Untuk mengetahui pengaruh testimonial terhadap purchase intention Pada Produk LA Florist, untuk Mengetahui Pengaruh Antara eWOM ( Elektronik Word Of Mouth ) terhadap Purchase Intention pada Produk LA Florist, untuk Mengetahui Pengaruh Antara Testimonial Dan eWOM ( Elektronik Word Of Mouth ) teradap Purchase Intention pada Produk LA Florist. Populasi dalam penelitian ini adalah konsumen pada produk LA Florist yang berjumlah 56. Sampel yang digunakan adalah seluruh dari total populasi. Metode pengumpulan data menggunakan kuisioner, obsevasi, wawancara, dan Studi kepustakaan. Hasil pengujian secara parsial menunjukan bahwa berpengaruh dan signifikan antara variabel testimonial terhadap Purchase Intention yang dibuktikan dengan nilai signifikan sebesar 0,000 dimana lebih kecil dari 0,05 (0,000 < 0,05). Hasil pengujian secara parsial menunjukan bahwa berpengaruh dan signifikan antara variabel eWOM terhadap Purchase Intention yang dibuktikan dengan nilai signifikan sebesar 0,005 dimana lebih kecil dari 0,05 (0,005 < 0,05). Berdasarkan hasil perhitungan diperoleh nilai signifikan adalah 0,000. Hal ini menunjukan bahwa nilai signifikan uji F variabel testimonial dan eWOM <0,05 yang berarti hasil dari pengujian simultan ini adalah testimonial dan eWOM berpengaruh terhadap Purchase Intention.


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