scholarly journals Machine Learning in Oncology: What Should Clinicians Know?

2020 ◽  
pp. 799-810
Author(s):  
Matthew Nagy ◽  
Nathan Radakovich ◽  
Aziz Nazha

The volume and complexity of scientific and clinical data in oncology have grown markedly over recent years, including but not limited to the realms of electronic health data, radiographic and histologic data, and genomics. This growth holds promise for a deeper understanding of malignancy and, accordingly, more personalized and effective oncologic care. Such goals require, however, the development of new methods to fully make use of the wealth of available data. Improvements in computer processing power and algorithm development have positioned machine learning, a branch of artificial intelligence, to play a prominent role in oncology research and practice. This review provides an overview of the basics of machine learning and highlights current progress and challenges in applying this technology to cancer diagnosis, prognosis, and treatment recommendations, including a discussion of current takeaways for clinicians.

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Muhammad Javed Iqbal ◽  
Zeeshan Javed ◽  
Haleema Sadia ◽  
Ijaz A. Qureshi ◽  
Asma Irshad ◽  
...  

AbstractArtificial intelligence (AI) is the use of mathematical algorithms to mimic human cognitive abilities and to address difficult healthcare challenges including complex biological abnormalities like cancer. The exponential growth of AI in the last decade is evidenced to be the potential platform for optimal decision-making by super-intelligence, where the human mind is limited to process huge data in a narrow time range. Cancer is a complex and multifaced disorder with thousands of genetic and epigenetic variations. AI-based algorithms hold great promise to pave the way to identify these genetic mutations and aberrant protein interactions at a very early stage. Modern biomedical research is also focused to bring AI technology to the clinics safely and ethically. AI-based assistance to pathologists and physicians could be the great leap forward towards prediction for disease risk, diagnosis, prognosis, and treatments. Clinical applications of AI and Machine Learning (ML) in cancer diagnosis and treatment are the future of medical guidance towards faster mapping of a new treatment for every individual. By using AI base system approach, researchers can collaborate in real-time and share knowledge digitally to potentially heal millions. In this review, we focused to present game-changing technology of the future in clinics, by connecting biology with Artificial Intelligence and explain how AI-based assistance help oncologist for precise treatment.


Entropy ◽  
2020 ◽  
Vol 23 (1) ◽  
pp. 18
Author(s):  
Pantelis Linardatos ◽  
Vasilis Papastefanopoulos ◽  
Sotiris Kotsiantis

Recent advances in artificial intelligence (AI) have led to its widespread industrial adoption, with machine learning systems demonstrating superhuman performance in a significant number of tasks. However, this surge in performance, has often been achieved through increased model complexity, turning such systems into “black box” approaches and causing uncertainty regarding the way they operate and, ultimately, the way that they come to decisions. This ambiguity has made it problematic for machine learning systems to be adopted in sensitive yet critical domains, where their value could be immense, such as healthcare. As a result, scientific interest in the field of Explainable Artificial Intelligence (XAI), a field that is concerned with the development of new methods that explain and interpret machine learning models, has been tremendously reignited over recent years. This study focuses on machine learning interpretability methods; more specifically, a literature review and taxonomy of these methods are presented, as well as links to their programming implementations, in the hope that this survey would serve as a reference point for both theorists and practitioners.


Author(s):  
Navjot Singh ◽  
Amarjot Kaur

The objective of the present chapter is to highlight applications of machine learning and artificial intelligence (AI) in clinical diagnosis of neurodevelopmental disorders. The proposed approach aims at recognizing behavioral traits and other cognitive aspects. The availability of numerous data and high processing power, such as graphic processing units (GPUs) or cloud computing, enabled the study of micro-patterns hundreds of times faster compared to manual analysis. AI, being a new technological breakthrough, enables study of human behavior patterns, which are hidden in millions of micro-patterns originating from human actions, reactions, and gestures. The chapter will also focus on the challenges in existing machine learning techniques and the best possible solution addressing those problems. In the future, more AI-based expert systems can enhance the accuracy of the diagnosis and prognosis process.


2020 ◽  
pp. practneurol-2020-002688
Author(s):  
Stephen D Auger ◽  
Benjamin M Jacobs ◽  
Ruth Dobson ◽  
Charles R Marshall ◽  
Alastair J Noyce

Modern clinical practice requires the integration and interpretation of ever-expanding volumes of clinical data. There is, therefore, an imperative to develop efficient ways to process and understand these large amounts of data. Neurologists work to understand the function of biological neural networks, but artificial neural networks and other forms of machine learning algorithm are likely to be increasingly encountered in clinical practice. As their use increases, clinicians will need to understand the basic principles and common types of algorithm. We aim to provide a coherent introduction to this jargon-heavy subject and equip neurologists with the tools to understand, critically appraise and apply insights from this burgeoning field.


2019 ◽  
Vol 21 (3) ◽  
pp. 280-290 ◽  
Author(s):  
Jenifer Sunrise Winter ◽  
Elizabeth Davidson

Purpose This paper aims to assess the increasing challenges to governing the personal health information (PHI) essential for advancing artificial intelligence (AI) machine learning innovations in health care. Risks to privacy and justice/equity are discussed, along with potential solutions. Design/methodology/approach This conceptual paper highlights the scale and scope of PHI data consumed by deep learning algorithms and their opacity as novel challenges to health data governance. Findings This paper argues that these characteristics of machine learning will overwhelm existing data governance approaches such as privacy regulation and informed consent. Enhanced governance techniques and tools will be required to help preserve the autonomy and rights of individuals to control their PHI. Debate among all stakeholders and informed critique of how, and for whom, PHI-fueled health AI are developed and deployed are needed to channel these innovations in societally beneficial directions. Social implications Health data may be used to address pressing societal concerns, such as operational and system-level improvement, and innovations such as personalized medicine. This paper informs work seeking to harness these resources for societal good amidst many competing value claims and substantial risks for privacy and security. Originality/value This is the first paper focusing on health data governance in relation to AI/machine learning.


Webology ◽  
2021 ◽  
Vol 18 (Special Issue 04) ◽  
pp. 501-513
Author(s):  
Nguyen Dinh Trung ◽  
Dinh Tran Ngoc Huy ◽  
Trung-Hieu Le

Our purpose to conduct this research is that we would like to present advantages and applications of internet of things (IoTs), Machine learning (ML), AI - Artificial intelligence and digital transformation in Education, Medicine-hospitals, Tourism and Manufacturing Sectors. In this paper authors will use methods such as empirical research and practices and experiences in infrared rays system applications in emerging markets such as Vietnam. Research Results find out that in education sector, ML and IoTs and AI has affected methods of teaching and methods of evaluating students in classroom and from then, teachers or instructors can decide suitable career development path for learners. Last but not least, ML and IoTs and AI together also has certain impacts in hospitals and medicine sector where public health data and patients information and diseases information are recorded and processed faster with Big Data. Till the end, we have enough information to propose implications for future researches on applications of machine learning in each specific sector and also, cybersecurity Risk management also need for implementing and applying ML and IoTs and AI.


2020 ◽  
Vol 9 (28) ◽  
pp. 123-129 ◽  
Author(s):  
D. Yu. Eliseeva ◽  
A. Yu. Fedosov ◽  
D. V. Agaltsova ◽  
O. L. Mnatsakanyan ◽  
K. K. Kuchmezov

Artificial intelligence, as a separate field of research, is currently experiencing a boom - new methods of machine learning and hardware are emerging and improving, and the results achieved change the life of society. Machine translation, handwriting recognition, speech recognition are changing our reality. The work of creating unmanned vehicles, voice assistants and other devices using these technologies is in an active process. The article examines the historical context of the artificial intelligence development, it evaluates the possibilities of its introduction into cyber games, as a safe and effective platform for testing new methods of machine learning. The promotion of such projects can increase the reputation of development companies, ensure increased user confidence in other products and, with a competent marketing strategy, cause a significant public resonance among video game fans, providing the developer with economic profit.


Author(s):  
Thomas Langer ◽  
Martina Favarato ◽  
Riccardo Giudici ◽  
Gabriele Bassi ◽  
Roberta Garberi ◽  
...  

Abstract Objective: Reverse Transcription-Polymerase Chain Reaction (RT-PCR) for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) diagnosis currently requires quite a long time span. A quicker and more efficient diagnostic tool in emergency departments could improve management during this global crisis. Our maingoal was assessing the accuracy of artificial intelligence in forecasting the resultsof RT-PCR for SARS-COV-2, using basic information at hand in all emergencydepartments.Methods: This is a retrospective study carried out between February 22 and March 16 2020 in one of the main hospitals in Milan, Italy. We screened for eligibility all patients admitted with influenza-like symptoms tested for SARS-COV-2.Patients under 12 years old, with no leukocyte formula performed in the ED,were excluded. Input data through artificial intelligence were made up of a combination of clinical, radiological and routine laboratory data upon hospital admission.Results: Among 199 patients subject to study (median [interquartile range] age 65 [46-78] years; 127 [63.8%] men), 124 [62.3%] resulted positive to SARS-COV-2. The best Machine Learning System reached an accuracy of 91.4% with 94.1% sensitivity and 88.7% specificity.Conclusion: Our study suggests that properly trained artificial intelligence algorithms may be able to predict correct results in RT-PCR for SARS-COV-2, using basic clinical data. If confirmed,on a larger-scale study, this approach could have important clinical and organizational implications.


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