Survival benefit of repeat liver resections for recurrent colorectal metastases: 143 cases. Association Francaise de Chirurgie.

PURPOSE Resection is the only chance for cure in patients with colorectal liver metastases (LM). Five-year survival rates are close to 25%. Unfortunately, recurrences occur in most patients. Some recurrent LM are technically resectable. The aim of this study was to determine the risks and benefits of repeat resections for recurrent LM. PATIENTS AND METHODS Data from 130 patients who received 143 repeat liver resections for recurrent LM were collected. In 116 patients, only the liver was involved, while 14 had both liver and extrahepatic recurrences. RESULTS In the first group, the operative mortality and morbidity rates were 0.9% and 24.7%, respectively. Two- and 3-year survival rates were 57% and 33%, respectively. Recurrences were observed in 66% of patients. Twelve patients underwent a third hepatectomy for recurrence. The mortality rate was nil, and the mean survival time was 12.5 months. In the group with liver and extrahepatic metastases, the operative mortality and morbidity rates were 0% and 25%. The mean survival time was 16 months. Eleven patients died and 13 had recurrences during the follow-up period. CONCLUSION Some hepatic recurrences after surgical excision of colorectal metastases can be resected with a low operative risk and with a long-term survival rate similar to that obtained after first resections. This emphasizes the need for a careful follow-up after hepatectomy for colorectal metastases to detect resectable recurrences.

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Bifurcated bypass in severe chronic limb threatening ischaemia

Vascular ◽

10.1177/1708538121999856 ◽

2021 ◽

pp. 170853812199985

Author(s):

Daniele Adami ◽

Michele Marconi ◽

Alberto Piaggesi ◽

Davide M Mocellin ◽

Raffaella N Berchiolli ◽

...

Keyword(s):

Survival Rates ◽

Primary Patency ◽

Free Survival ◽

Mortality And Morbidity ◽

Bypass Patency ◽

Stage 4 ◽

Endovascular Approach ◽

The Mean ◽

Clinical Records

Objectives Revascularization according to the angiosome concept is of proven importance for limb salvage in chronic limb threatening ischaemia but it is not always practicable. Bifurcated bypasses could be considered as an option when an endovascular approach is not feasible or has already failed and a single bypass would not allow direct revascularization of the ischaemic area. Bifurcated bypasses are characterized by landing on two different arteries, the main artery (in direct continuity with the foot vessels) and the secondary one (perfusing the angiosome district). The aim of this study is to evaluate the safety and effectiveness of bifurcated bypass in chronic limb threatening ischaemia. Methods Thirty-five patients were consecutively treated with a bifurcated bypass for chronic limb threatening ischaemia from January 2014 to December 2019 in a single vascular surgery centre. Data from clinical records and operative registers were collected prospectively in an electronic database and retrospectively analysed. Primary and primary assisted bypass patency, amputation-free survival, morbidity and mortality rates at 12 and 24 months were analysed. Results Mean follow-up period was 25.1 months (range 2–72 months). Thirty-six bifurcated bypasses were performed on 35 patients (age 75.3 ± 7.2 years; 69.4% were male). According to Wound, Ischemia, foot Infection classification 22.2% belonged to stage 3 and 77.8% to stage 4 and the mean Rutherford’s class was 5.1 ± 0.7. Immediate technical success was 100%. Early mortality and morbidity rates were respectively 5.5%, and 33.3%; foot surgery was performed in 50% of cases with wound healing in all patients. Primary patency and primary assisted bypass patency were 96.7% and 100% at 6 months; 85.2% and 92% at 12 months, 59.9% and 73.4% at 24 months, respectively. Amputation-free survival at 12 and 24 months was, respectively, 95.6% and 78.8%. Overall survival rates at 12 and 24 months were respectively 94.4% and 91.6%. Conclusions Bifurcates bypass can provide good results in patients with chronic limb threatening ischaemia without endovascular option, especially in diabetic ones. Bifurcated bypass is a complex surgical solution, both to be planned and performed, and it is quite invasive for frail patients that should be accurately selected.

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Relationship Between Survival Rate and Survival-Time of Rabbits, Oryctolagus-Cuniculus (L), Challenged With Myxoma Virus

Australian Journal of Zoology ◽

10.1071/zo9950303 ◽

1995 ◽

Vol 43 (3) ◽

pp. 303 ◽

Cited By ~ 5

Author(s):

I Parer

Keyword(s):

Survival Time ◽

Small Groups ◽

Regression Line ◽

Survival Rates ◽

Myxoma Virus ◽

Survival Times ◽

Mean Survival Time ◽

The Past ◽

Survival Percentage ◽

The Mean

The mean survival times of small groups of rabbits challenged with myxoma virus have been used to estimate survival rates and to allocate virulence grades to field strains of myxoma virus. The slope of the regression Line relating survival percentage to mean survival time in days was shown to be less steep than has been previously estimated. This overestimation of the regression slope has, in the past, resulted in most field strains of myxoma virus being allocated to the Grade III level of virulence when allocation to Grade I would have been more appropriate.

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Epidemiological Study of Adamantinoma from US Surveillance, Epidemiology, and End Results Program: III Retrospective Analysis

Journal of Oncology ◽

10.1155/2020/2809647 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8

Author(s):

Mahmut Nedim Aytekin ◽

Recep Öztürk ◽

Kamil Amer

Keyword(s):

Marital Status ◽

Survival Time ◽

Survival Rates ◽

Age Groups ◽

Tumor Location ◽

Cancer Surveillance ◽

Survival Duration ◽

Low Grade ◽

The Mean

Objective. Adamantinomas are rare low-grade malignant bone tumors. This study aims to describe the demographic characteristics and survival rates of patients suffering from adamantinomas. Methods. The National Institute of Cancer Surveillance, Epidemiology, and Recent Results (SEER) database was used, and patients diagnosed with adamantinoma between 1973 and 2016 were screened. Patients were classified according to sex, age, race/ethnicity, and marital status, and also tumors were classified according to year of diagnosis, laterality, type of treatment, and follow-up. Results. The mean age of patients was 30.8 ± 16.7 (range: 4–75). A total of 92 patients were identified; of these, 43 were females and 49 were males. The mean follow-up period was 138.1 ± 90.3 (range: 1–156) months. Mean survival duration was 287.8 ± 15.4 (95% CI: 257.7–317.9) months. Five- and ten-year survival rates were 98.8% and 91.5%, respectively. Besides, survival time was also observed to be independent of gender, age groups, race, marital status, tumor location, and year of diagnosis. Conclusion. Adamantinoma is a very rare bone tumor that affects the long bones in lower extremities and is more common in men. Five- and 10-year survival prognoses are reasonably satisfactory. Also, survival time is independent of variables such as gender, age, and tumor location.

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Clinical and radiological outcomes of the Ivory arthroplasty for trapeziometacarpal joint osteoarthritis with a minimum of 5 years of follow-up: a prospective single-centre cohort study

Journal of Hand Surgery (European Volume) ◽

10.1177/1753193413488494 ◽

2013 ◽

Vol 38 (8) ◽

pp. 866-874 ◽

Cited By ~ 29

Author(s):

J. F. Goubau ◽

C. K. Goorens ◽

P. Van Hoonacker ◽

B. Berghs ◽

D. Kerckhove ◽

...

Keyword(s):

Functional Outcome ◽

Rating Scale ◽

Numerical Rating Scale ◽

Survival Rates ◽

Trapeziometacarpal Joint ◽

Term Survival ◽

Numerical Rating ◽

Trapeziometacarpal Joint Osteoarthritis ◽

The Mean

We present the results of a 5 year prospective follow-up study on the functional outcome after total replacement of the trapeziometacarpal joint with the Ivory prosthesis (Memometal, Stryker Corporate, Kalamazoo, Michigan, USA) in 22 patients. The female to male ratio was 21:1 and the mean age was 66 (range 54–78) years. The mean follow-up period was 67 (range 60–77) months after operation. Patient satisfaction was high. The mobility of the operated thumb was restored to a range of motion comparable to the contralateral thumb. Key pinch and grip strength improved by 13% and 31%, respectively. Overall function, according to Quick Disabilities of the Arm, Shoulder and Hand (QuickDASH) score, improved by 59%. Pain decreased by 85% according to the numerical rating scale. Radiological evaluation revealed no loosening of the implant after 5 years except in one patient who required revision due to polythene wear with secondary joint instability. Another patient had asymptomatic polythene wear that required no revision but remains in follow-up. The 5 year overall survival of the prosthesis was 95%. These medium-term results suggest that the Ivory arthroplasty is a reliable option for treating advanced trapeziometacarpal arthritis, because it appears to give a very good functional outcome and has the potential for long-term survival rates.

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CLO19-061: Clinical Features and Prognosis of Head and Neck Cancer in Patients With Esophagus Cancer

Journal of the National Comprehensive Cancer Network ◽

10.6004/jnccn.2018.7140 ◽

2019 ◽

Vol 17 (3.5) ◽

pp. CLO19-061

Author(s):

Weihui Zheng ◽

Weimin Mao ◽

Jianlin Lou

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Survival Time ◽

Neck Cancer ◽

Survival Rates ◽

Metachronous Cancer ◽

Esophagus Cancer ◽

Mean Survival Time ◽

Significant Difference ◽

The Mean

Objective: This study investigated the clinical and prognostic characteristics of head and neck cancer in patients with esophagus cancer. Methods: Information on 124 patients with head and neck cancer with esophagus cancer was collected from head and neck and thoracic surgery departments between January 2007 and December 2016 in Zhejiang Cancer Hospital. The incidence of synchronous and metachronous cancer was described. The clinical characteristics and prognosis were also compared in synchronous and metachronous cancer. The number of hospitalization and different treatments were analyzed the affection on the survival time. Results: 32 cases were synchronous cancer and 72 cases were metachronous cancer. The rate of surgery and the number of hospitalization were significantly different in synchronous and metachronous cancer (χ2=4.661; P<.05). The 1-year, 3-year, and 5-year survival rates were 39.9%, 19.9%, and15.2%, respectively in patients with synchronous cancer and the mean survival time was 18.4±6.2 months. In contrast, the survival rates were 78.7%, 77.8%, and 59.1% respectively in metachronous cancer and the mean survival time was 122.2±17.2 months. There was a significant difference between the 2 groups (χ2=10.934; P=.001). The number of hospitalizations greater than or equal to 5 times were significantly different from those with less than 5 times (χ2=10.574; P=.001). There was no statistically significant difference in the improvement of OS by single operation, chemotherapy, and target treatment. The P value was only slightly less than .05 in the radiation therapy. Conclusions: Head and neck cancer in patients with esophagus cancer have a high survival rate through active combined-modality therapies, especially in metachronous carcinoma.

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Survival Rate of Cholangiocarcinoma, Hepatocellular Patients Received Cannabis Treatment

10.21203/rs.3.rs-1030279/v1 ◽

2021 ◽

Author(s):

Narisara Phansila ◽

Ranee Wongkongdech ◽

Chaiyasit Sittiwech

Keyword(s):

Palliative Care ◽

Survival Rate ◽

Treatment Group ◽

Mortality Rate ◽

Survival Time ◽

Cox Regression ◽

Survival Rates ◽

Term Survival ◽

Medicinal Cannabis

Abstract Introduction:Cholangiocarcinoma (CCA) incidence in Northeastern Thailand is very high, and a major cause of mortality CCA patients typically have a poor prognosis and short-term survival rate, due to late-stage diagnosis. . Thailand is , the first Southeast Asian country to approve medicinal cannabis treatment, especially for palliative care with advanced cancer patients..Patients and methods:A retrospectively cohort comparative study of , survival rates among 491 newly diagnosed advanced CCA patients was carried out between September 2019 and 30 July, 2021; (404 patients in a standard palliative care pain management treatment group (ST), and 87 in a medicinal cannabis treatment group (CT). CCA Patients were recruited from 4 tertiary hospitals and 2 secondary hospitals in five provinces of Northeast Thailand. The cumulative survival rates were calculated by the Kaplan-Meier method, and independent prognostic factors were investigated using Cox regression.Results:For ST patients there was a total follow-up time of 790 person-months, with a , mortality rate of 48.35/ 100 person-years. For CT patients the total follow-up time was 476 person-months, with mortality rate of 10.9./ 100 person-years. The median survival time after registration at a palliative clinic was 0.83 months (95%CI: 0.71-0.95) for ST and 5.66 months (95%CI: 1.94-9.38) for CT None of the demographic factors were significantly associated with survival time for either ST or CT. Comparing ST with CT, there was a difference statistically significant in age, sex, cancer treatment and period of diagnosis with advanced CCA,HCC to registration factors (p-value<0.05)Conclusions:The medicinal cannabis group had an increase post CCA diagnosis survival rate.. Our findings support the importance of early access to palliative cannabis clinic before caner’s terminal and accelerating phase close to death.

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P1345CATHETER FAILURE AND MORTALITY IN HEMODIALYSIS PATIENTS WITH THE TUNNELLED-CUFFED CATHERTER TIP POSITIONED IN THE INFERIOR VENA CAVA

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfaa142.p1345 ◽

2020 ◽

Vol 35 (Supplement_3) ◽

Author(s):

Lu Cheng ◽

Shen-Ju Gou ◽

Jing Yi ◽

Qian Ren ◽

Tian-Lei Cui ◽

...

Keyword(s):

Inferior Vena Cava ◽

Survival Time ◽

Vascular Access ◽

Inferior Vena ◽

Survival Rates ◽

Vena Cava ◽

Mean Survival Time ◽

Kaplan Meier ◽

Catheter Tip ◽

The Mean

Abstract Background and Aims For patients with multiple central vein obstruction (CVO) and exhausted all options for arteriovenous accesses, how to establish a new effective vascular access is an urgent problem, and the key point to solve this problem is where to locate the tip of catheter. This study focused on these patients and investigated the safety and efficient of tunnelled cuffed catheter (TCC) with the tip placed in the inferior vena cava (IVC). Method Thirty-three maintenance haemodialysis patients with vascular access malfunction presented to West China Hospital of Sichuan University from March 2013 to December 2016 were included in this retrospective study and followed up until their catheter failure or death or until June 30, 2019. The short-term efficacy and safety of the procedure placing TCC tip in IVC were observed. The survival rates of TCC with catheter tip in IVC and patients were analysed. Results All thirty-three patients achieved adequate blood flow to complete the first session of haemodialysis after catheterization procedure and no obvious complications, such haemorrhage, arrhythmia and pulmonary embolism. The mean survival time of the TCC with catheter tip in IVC was 58.5 (95% CI 48.8–63.4) months by Kaplan–Meier analysis. The survival rates of TCC with catheter tip in IVC were 87, 83, 75, 71% in 1, 2, 3, 4 years, respectively. The highest incidence of catheter dysfunction was at 12 months after catheterization. The mean survival time of patients was 56.2 (95% CI 46.9–65.4) months by Kaplan–Meier analysis. The patient survival rates were 88, 82, 70, 67 % in 1, 2, 3, 4 years, respectively. The highest mortality was at 12 months after catheterization. Conclusion Our study suggested that placement of the tunnelled-cuffed catheter tip in the IVC was safety and efficacy in the end-stage haemodialysis patients who has exhausted vascular resources with CVO. The TCC with tip in the IVC was feasible to be a long-term vascular access for these patients.

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Surgical Treatment of Double Valve Endocarditis

The Heart Surgery Forum ◽

10.1532/hsf98.2013280 ◽

2014 ◽

Vol 17 (1) ◽

pp. 28

Author(s):

Serpil Tas ◽

Taylan Adademir ◽

Eylem Yayla Tuncer ◽

Arzu Antal Donmez ◽

Ebru Bal Polat ◽

...

Keyword(s):

Infective Endocarditis ◽

Aortic Valve ◽

Survival Rates ◽

Pacemaker Implantation ◽

Prosthetic Valve Endocarditis ◽

Actuarial Survival ◽

Mortality And Morbidity ◽

Septic Embolization ◽

The Mean

Background: We have retrospectively analyzed the results of the operations made for aortic infective endocarditis with mitral involvement in a single center in 19 years.Methods: From May 1992 to January 2011, we have operated on 72 patients with infective endocarditis of the aortic valve with mitral valve involvement. Fifty-two patients (72.2%) were male and the mean age was 40.5 � 15.5 (9-73) years. The blood cultures were positive in 33 patients (45.8%) and the most commonly identified microorganism was Streptococcus. Nine patients (12.5%) had prosthetic valve endocarditis. The mean duration of follow-up was 6.8 � 4.7 (0.1-16.9) years, adding up to a total of 156.1 patient/years.Results: A total of 155 procedures were performed on these 72 patients. The most commonly performed procedure was aortic valve replacement, in 63 patients (87.5%). Aortic annular involvement was present in 9 cases (12.5%). In-hospital mortality was seen in 13 patients (18.1%). Postoperatively, 13 (18.1%) patients had low cardiac output, 9 (12.5%) had heart block, and only 1 of them required permanent pacemaker implantation. The actuarial survival rates for 1, 5, and 10 years were 96.4% � 2.5%, 84.4% � 5.1%, and 77.4 � 6.7%, respectively.Conclusions: Double-valve endocarditis is a serious condition and the surgeon must be aware of the high rates of mortality and morbidity in these patients. Although no association was found, heart blocks and septic embolization must be handled with caution. The patients generally do well after surgery, and recurrences and reoperations decrease by the second year after operation.

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Minimally Invasive Transaortic Repair of the Mitral Valve

The Heart Surgery Forum ◽

10.1532/hsf98.20101133 ◽

2011 ◽

Vol 14 (4) ◽

pp. 232 ◽

Cited By ~ 2

Author(s):

Orlando Santana ◽

Joseph Lamelas

Keyword(s):

Mitral Valve ◽

Aortic Valve ◽

Mitral Regurgitation ◽

Aortic Valve Replacement ◽

Minimally Invasive ◽

Valve Replacement ◽

Operative Mortality ◽

The Mean ◽

Transaortic Approach

Objective: We retrospectively evaluated the results of an edge-to-edge repair (Alfieri stitch) of the mitral valve performed via a transaortic approach in patients who were undergoing minimally invasive aortic valve replacement.Methods: From January 2010 to September 2010, 6 patients underwent minimally invasive edge-to-edge repair of the mitral valve via a transaortic approach with concomitant aortic valve replacement. The patients were considered to be candidates for this procedure if they were deemed by the surgeon to be high-risk for a double valve procedure and if on preoperative transesophageal echocardiogram the mitral regurgitation jet originated from the middle portion (A2/P2 segments) of the mitral valve.Results: There was no operative mortality. Mean cardiopulmonary bypass time was 137 minutes, and mean cross-clamp time was 111 minutes. There was a significant improvement in the mean mitral regurgitation grade, with a mean of 3.8 preoperatively and 0.8 postoperatively. The ejection fraction remained stable, with mean preoperative and postoperative ejection fractions of 43.3% and 47.5%, respectively. Follow-up transthoracic echocardiograms obtained at a mean of 33 days postoperatively (range, 8-108 days) showed no significant worsening of mitral regurgitation.Conclusion: Transaortic repair of the mitral valve is feasible in patients undergoing minimally invasive aortic valve replacement.

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Hybrid Endovascular Repair of Thoracoabdominal Aorta: Early Results

The Heart Surgery Forum ◽

10.1532/hsf98.2014315 ◽

2014 ◽

Vol 17 (3) ◽

pp. 146

Author(s):

Osman Tansel Darcin ◽

Mehmet Kalender ◽

Ayse Gul Kunt ◽

Okay Guven Karaca ◽

Ata Niyazi Ecevit ◽

...

Keyword(s):

Endovascular Repair ◽

Therapeutic Option ◽

Complete Recovery ◽

Aortic Aneurysms ◽

Thoracoabdominal Aorta ◽

Mortality And Morbidity ◽

Early Results ◽

The Mean ◽

Procedural Success

Background: Thoracoabdominal aortic aneurysms (TAAA) present a significant clinical challenge, as they are complex and require invasive surgery. In an attempt to prevent considerably high mortality and morbidity in open repair, hybrid endovascular repair has been developed by many authors. In this study, we evaluated the early-term results obtained from this procedure.Methods: From November 2010 to February 2013, we performed thoracoabdominal hybrid aortic repair in 18 patients. The mean age was 68 years (12 men, 6 women). All of the patients had significant comorbidities. Follow-up computed tomography (CT) scans were performed at 1 week, 3 months, 6 months, and annually thereafter.Results: All patients were operated on in a staged procedure and stent graft deployment was achieved. Procedural success was achieved in all cases. All patients were discharged with complete recovery. No endoleaks weres detected in further CT examination.Conclusion: Our results suggests that hybrid debranching and endovascular repair of extensive thoracoabdominal aneurysms represents a suitable therapeutic option to reduce the morbidity and mortality of TAAA repair, particularly in those typically considered at high risk for standard repair.

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