Prospective Study of the Correlation Between Postoperative Computed Tomography Scan and Primary Surgeon Assessment in Patients With Advanced Ovarian, Tubal, and Peritoneal Carcinoma Reported to Have Undergone Primary Surgical Cytoreduction to Residual Disease 1 cm or Less

2007 ◽  
Vol 25 (31) ◽  
pp. 4946-4951 ◽  
Author(s):  
Dennis S. Chi ◽  
Pedro T. Ramirez ◽  
Jerrold B. Teitcher ◽  
Svetlana Mironov ◽  
Debra M. Sarasohn ◽  
...  

Purpose To compare surgeons' operative assessments of residual disease (RD) to those identified on postoperative computed tomography (CT) scans in patients with advanced ovarian carcinoma reported to have undergone optimal primary cytoreduction. Patients and Methods All patients at one of two institutions, who were scheduled to have primary surgery for presumed advanced ovarian cancer, were asked to consent to a postoperative CT scan if cytoreduction to ≤ 1 cm RD was reported. CT scan findings were graded using a qualitative analysis scale from 1 (normal) to 5 (definitely malignant). Results From January 2001 to September 2006, 285 patients were enrolled. A total of 78 patients met eligibility criteria and had postoperative CT scans. In 41 cases (52%), postoperative scan findings correlated with the surgical report of no RD more than 1 cm, and in seven cases (9%), the CT findings were indeterminate. In 10 cases (13%), more than 1 cm RD was noted by the radiologist as probably malignant, and in 20 cases (26%), definitely malignant. In these 30 cases, the radiologically reported median largest residual mass was 1.9 cm (range, 1.1 to 5.1), with RD more than 1 cm reported most commonly in the right upper quadrant (15 patients [50%]) and central abdomen (nine patients [30%]). Conclusion There was only a 52% correlation between surgeons' assessments and postoperative CT scan evaluations of RD in patients reported to have undergone optimal cytoreduction. Further study is required to determine whether this lack of correlation is due to rapid interval tumor regrowth, RD underestimated by the surgeons, and/or overestimated by the radiologists; and to determine the clinical implications of these discrepancies.

2007 ◽  
Vol 25 (4) ◽  
pp. 384-389 ◽  
Author(s):  
Allison E. Axtell ◽  
Margaret H. Lee ◽  
Robert E. Bristow ◽  
Sean C. Dowdy ◽  
William A. Cliby ◽  
...  

Purpose Identify features on preoperative computed tomography (CT) scans to predict suboptimal primary cytoreduction in patients treated for advanced ovarian cancer in institution A. Reciprocally cross validate the predictors identified with those from two previously published cohorts from institutions B and C. Patients and Methods Preoperative CT scans from patients with stage III/IV epithelial ovarian cancer who underwent primary cytoreduction in institution A between 1999 and 2005 were retrospectively reviewed by radiologists blinded to surgical outcome. Fourteen criteria were assessed. Crossvalidation was performed by applying predictive model A to the patients from cohorts B and C, and reciprocally applying predictive models B and C to cohort A. Results Sixty-five patients from institution A were included. The rate of optimal cytoreduction (≤ 1 cm residual disease) was 78%. Diaphragm disease and large bowel mesentery implants were the only CT predictors of suboptimal cytoreduction on univariate (P < .02) and multivariate analysis (P < .02). In combination (model A), these predictors had a sensitivity of 79%, a specificity of 75%, and an accuracy of 77% for suboptimal cytoreduction. When model A was applied to cohorts B and C, accuracy rates dropped to 34% and 64%, respectively. Reciprocally, models B and C had accuracy rates of 93% and 79% in their original cohorts, which fell to 74% and 48% in cohort A. Conclusion The high accuracy rates of CT predictors of suboptimal cytoreduction in the original cohorts could not be confirmed in the cross validation. Preoperative CT predictors should be used with caution when deciding between surgical cytoreduction and neoadjuvant chemotherapy.


2019 ◽  
Vol 08 (03) ◽  
pp. 121-125
Author(s):  
Ajay Kumar ◽  
Alok Tripathi ◽  
Shobhit Raizaday ◽  
Shilpi Jain ◽  
Satyam Khare ◽  
...  

Abstract Background and Aim The purpose of present study was to obtain comprehensive data of morphometric and anatomical details of jugular foramen. Materials and Methods The study was performed on 30 dry adult human skulls along with computed tomography (CT) scans from 30 adult patients. The parameters observed were dimensions, shape, margins, confluence, septations, and distance from jugular foramen to mastoid base. Result In the dry skull observations, only anteroposterior diameter (APD) was significantly different between the right and left side, while for the CT scan observations both transverse diameter and APD exhibit significant difference. Conclusion We believe that data from the present study will help radiologists and neurosurgeons for diagnosis and treatment of skull base pathology around jugular foramen.


2018 ◽  
Vol 8 ◽  
pp. 21-27
Author(s):  
Kyumi Vinod Shethiya ◽  
Gauri S. Vichare

Introduction Cortical bone thickness is an important factor in mini implant stability. Many studies have evaluated cortical bone thickness by different methods, but this study is a step ahead in measuring cortical bone in wet mandibles from cadavers comparing thickness values from computed tomograms to images from a stereomicroscope (SM). In this study, we investigated buccal cortical bone thickness at three interdental areas using computed tomography (CT) scan and SM. Methods From the CT scans of 30 wet human cadaveric mandibles, 2-dimensional slices through three interdental area (mesial of canine, interpremolar, and inter-molar) were generated. On these, cortical bone thickness was measured at 2, 4, and 6 mm from the cementoenamel junction (CEJ). The cortical bone thickness at same areas was compared with an SM. Results By both methods, it was observed that thickness of cortical bone increased from mesial of canines toward the premolar region and then decreased in the molar region. Increase in thickness of cortical bone was observed with increase in height from the CEJ toward the apical region up to 6 mm. CT scans underestimated the measurements as compared to the SM method. Conclusions The mean buccal cortical bone thickness at all interdental sites at 2, 4, and 6 mm from CEJ was 1.7 ± 0.4 by the CT scan method and 1.9 ± 0.5 by the SM method, indicating that results observed with the CT method were underestimated by 11% than SM method.


PEDIATRICS ◽  
1980 ◽  
Vol 66 (3) ◽  
pp. 432-437
Author(s):  
Gerald Silverboard ◽  
Anthony Lazzara ◽  
Peter A. Ahmann ◽  
James F. Schwartz

Computed tomography (CT) scan is the most accurate method for diagnosing intracerebral hemorrhage in the high-risk preterm infant. The present study was undertaken to evaluate lumbar puncture (LP) as a reliable means of diagnosing such hemorrhages. Forty eight infants less than 35 weeks gestation, requiring intensive care, were evaluated by CT scan at 48 to 96 hours of life, and serial LPs were performed. The initial LP preceded the CT scan by one to four hours and repeat LPs were done three and five days later if the initial CT scan revealed intracerebral hemorrhage. The initial LP was successfully performed in 28 of 48 infants. Of these 48 infants, 15 had hemorrhage by CT scan. The initial LP was consistent with the diagnosis on scan in eight of these 15. In the other seven infants, initial LP was normal in three, traumatic in one, and unsuccessful in three. The second LP was consistent with hemorrhage in four of the latter seven. Thus, in only eight of 15 infants, in whom CT scans revealed intracerebral hemorrhage, was the initial LP useful in confirming the diagnosis. Furthermore, LPs showed bloody cerebrospinal fluid in 10 of 18 infants whose CT scans were normal. At the present time LP cannot be considered a reliable means of identifying infants with subependymal-intraventricular hemorrhage.


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Meidianty Tandi ◽  
Vonny N. Tubagus ◽  
Martin L. Simanjuntak

Abstract: Lung tumor has become one of the most common tumors in the world. Lung tumor is the growth of abnormal lumps on lung tissue that could be benign or malignant, derived from malignant tumors of primary epithelial tissue in respiratory tract especially bronchus that could invade nearby tissue structures, and potentially spread throughout the body by bloodstream and lymphatic system. Approximately 1.59 billion people worldwide died from lung malignancy resulting from the increasing of smoking habit which is one of the risk factors of lung tumor. CT scan is the chosen modality on diagnosing the suspicion of lung tumor and also to evaluate the tumor itself. The aim of this study is to identify the CT scan images on patients with lung tumor. Retrospective descriptive study was conducted on November 2015. The data was obtained from thorax CT scan examination request forms and eventually 41 cases of lung tumor were found eligible according to inclusion criteria. Based on radiologic diagnosis there were 41 cases (39,4%) of lung tumor. The patients were mostly male with 35 patients (85.4%), the largest age group is middle aged adults with 30 patients (73.2%), and the most common site of tumor was the right lung with 22 cases (53.7%), moreover the most complication of lung tumor is pleural effusion with 13 cases (31.7%). Conclusion: Lung tumor is one of malignancies that become risk factor of deaths worldwide.Keywords: lung tumor, computed tomography scan. Abstrak: Tumor paru menjadi salah satu tumor yang paling banyak ditemui di dunia. Tumor paru adalah tumbuhnya benjolan abnormal pada jaringan paru yang dapat bersifat jinak atau ganas, serta berasal dari tumor ganas epitel primer saluran nafas terutama bronkus yang dapat menginvasi struktur jaringan disekitarnya dan berpotensi menyebar ke seluruh tubuh melalui aliran darah dan sistem limfatik. Terdapat sekitar 1,59 miliar orang di dunia meninggal dunia akibat keganasan pada paru-paru karena tingginya kebiasaan merokok yang merupakan salah satu faktor resiko terjadinya tumor pada paru. CT scan menjadi modalitas terpilih untuk menegakkan diagnosis kecurigaan tumor paru dan untuk mengevaluasi tumor paru tersebut. Penelitian ini bertujuan untuk mengetahui gambaran CT scan pada penderita tumor paru dan menggunakan jenis penelitian deskriptif retropektif yang dilakukan pada bulan November 2015. Data diperoleh melalui lembaran permintaan pemeriksaan CT scan toraks dan didapatkan sebanyak 41 kasus tumor paru yang masuk dalam kriteria inklusi.Terdapat 41 kasus (39,4 %) tumor paru berdasarkan diagnosis radiologis. Penderita terbanyak adalah laki-laki 35 orang (85,4%), golongan umur terbanyak adalah umur 41-65 tahun yaitu 30 orang (73,2%), lokasi tumor paru terbanyak pada pulmo dextra yaitu 22 kasus (53,7%) dan komplikasi terbanyak adalah tumor paru dengan efusi pleura saja sebanyak 13 kasus (31,7%). Simpulan: Tumor paru merupakan salah satu penyakit keganasan yang menjadi faktor resiko kematian di seluruh dunia.Kata kunci: tumor paru, computed tomography scan.


PEDIATRICS ◽  
1981 ◽  
Vol 68 (1) ◽  
pp. 144-144
Author(s):  
Joseph J. Volpe

I read with interest the article by Silverboard et al, "Comparison of Lumbar Puncture with Computed Tomography Scan as an Indicator of Intracerebral Hemorrhage in the Preterm Infant."1 Although the report provides interesting and useful information, I believe that the authors' conclusions might be misinterpreted. I write to offer a few comments. The authors' stated purpose was "to evaluate the reliability of lumbar puncture in comparison with [computed tomography] CT scan in the diagnosis of [subependymal/intraventricular hemorrhage] SEH/IVH."1


Author(s):  
Majid Anwer ◽  
Atique Ur Rehman ◽  
Farheen Ahmed ◽  
Satyendra Kumar ◽  
Md Masleh Uddin

Abstract Introduction Traumatic head injury with extradural hematoma (EDH) is seen in 2% of patients. Development of EDH on the contralateral side is an uncommon complication that has been reported in various case reports. Case Report We report here a case of an 18-year-old male who had a road traffic injury. He was diagnosed as a case of left-sided large frontotemporoparietal acute extradural bleed with a mass effect toward the right side. He was managed with urgent craniotomy and evacuation of hematoma. A noncontrast computed tomography (NCCT) scan performed 8 hours after postoperative period showed a large frontotemporoparietal bleed on the right side with a mass effect toward the left side. He was again taken to the operating room and right-sided craniotomy and evacuation of hematoma were performed. A postoperative NCCT scan revealed a resolved hematoma. The patient made a complete recovery in the postoperative period and is doing well. Conclusion Delayed onset epidural hematoma is diagnosed when the initial computed tomography (CT) scan is negative or is performed early and when late CT scan performed to assess clinical or ICP deterioration shows an EDH. The diagnosis of such a condition requires a high index of suspicion based on the mechanism of injury along with fracture patterns. Additionally, change in pupillary size, raised intracranial pressure, and bulging of the brain intraoperatively are additional clues for contralateral bleeding. Neurologic deterioration may or may not be associated with delayed EDH presentation. An early postoperative NCCT scan within 24 hours is recommended to detect this complication with or without any neurologic deterioration.


2019 ◽  
Vol 58 (6) ◽  
pp. 671-676
Author(s):  
Amy M. West ◽  
Pierre A. d’Hemecourt ◽  
Olivia J. Bono ◽  
Lyle J. Micheli ◽  
Dai Sugimoto

The objective of this study was to determine diagnostic accuracy of magnetic resonance imaging (MRI) and computed tomography (CT) scans in young athletes diagnosed with spondylolysis. A cross-sectional study was used. Twenty-two young athletes (14.7 ± 1.5 years) were diagnosed as spondylolysis based on a single-photon emission CT. Following the diagnosis, participants underwent MRI and CT scan imaging tests on the same day. The sensitivity and false-negative rate of the MRI and CT scans were analyzed. MRI test confirmed 13 (+) and 9 (−) results while CT test showed 17 (+) and 5 (−) results. The sensitivity and false-negative rate of MRI were, respectively, 59.1% (95% confidence interval [CI] = 36.7% to 78.5%) and 40.9% (95% CI = 21.5% to 63.3%). Furthermore, the sensitivity and false-negative rate of CT scan were 77.3% (95% CI = 54.2% to 91.3%) and 22.7% (95% CI = 0.09% to 45.8%). Our results indicated that CT scan is a more accurate imaging modality to diagnose spondylolysis compared with MRI in young athletes.


Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Shahram Majidi ◽  
Basit Rahim ◽  
Sarwat I Gilani ◽  
Waqas I Gilani ◽  
Malik M Adil ◽  
...  

Background: The temporal evolution of intracerebral hematomas and perihematoma edema in the ultra-early period on computed tomographic (CT) scans in patients with intracerebral hemorrhage (ICH) is not well understood. We aimed to investigate hematoma and perihematoma changes in “neutral brain” models of ICH. Methods: One human and 6 goat cadaveric heads were used as “neutral brains” to provide physical properties of the brain without any biological activity or new bleeding. ICH was induced by slow injection of 4 ml of fresh blood into the right basal ganglia of the goat brains. Similarly, 20 ml of fresh blood was injected deep into the white matter of the human cadaver head in each hemisphere. Serial CT scans of the heads were performed at 0, 1, 3, and 5 hours after inducing ICH. Analyze software (AnalyzeDirect, Overland Park, KS) was used to measure hematoma and perihematoma hypodensity volumes in the baseline and follow up CT scans. Results: The initial hematoma volumes of 11.6 ml and 10.5 ml in the right and the left hemispheres of the human cadaver brain gradually decreased to 6.6 ml and 5.4 ml at 5 hours, showing 43% and 48% retraction of hematoma, respectively. The volume of the perihematoma hypodensity in the right and left hemisphere increased from 2.6 ml and 2.2 ml in the 1 hour follow up CT scans to 4.9 ml and 4.4 ml in the 5 hour CT scan, respectively. Hematoma retraction was also observed in all six ICH models in the goat brains. The mean ICH volume in the goat heads was decreased from 1.49 ml in the baseline CT scan to 1.01 ml in the 5 hour follow up CT scan showing 29.6% hematoma retraction. Perihematoma hypodensity was visualized in 70% of ICH in goat brains, with an increasing mean hypodensity volume of 0.4 ml in the baseline CT scan to 0.8 ml in the 5 hour follow up CT scan. Conclusion: Our study demonstrated that substantial hematoma retraction and perihematoma hypodensity occurs in intracerebral hematomas in the absence of any new bleeding or biological activity of the surrounding brain. Such observations suggest that active bleeding is underestimated in patients with no or small hematoma expansion and our understanding of perihematoma hypodesity needs to be reconsidered.


2021 ◽  
pp. 000313482110474
Author(s):  
Gwyneth A. Sullivan ◽  
Nicholas J. Skertich ◽  
Kody B. Jones ◽  
Michael Williams ◽  
Brian C. Gulack ◽  
...  

Intussusception is the most common cause of bowel obstruction in infants four to ten months old and is commonly idiopathic or attributed to lymphoid hyperplasia. Our patient was a 7-month-old male who presented with two weeks of intermittent abdominal pain associated with crying, fist clenching and grimacing. Ultrasound demonstrated an ileocolic intussusception in the right abdomen. Symptoms resolved after contrast enemas, and he was discharged home. He re-presented similarly the next day and was found to be COVID-19 positive. Computed tomography scan demonstrated a left upper quadrant ileal-ileal intussusception. His symptoms spontaneously resolved, and he was discharged home. This suggests that COVID-19 may be a cause of intussusception in infants, and infants presenting with intussusception should be screened for this virus. Additionally, recurrence may happen days later at different intestinal locations. Caregiver education upon discharge is key to monitor for recurrence and need to return.


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