Stopping Trials Early for Positive Results: The Need to Know How Much

2009 ◽  
Vol 27 (21) ◽  
pp. e29-e29 ◽  
Author(s):  
Carl D. Atkins
Keyword(s):  
Know How ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 3517
Author(s):  
Hsin-Chi Ko

Many scholars consider Kwang-Chung Yu (1928–2017) a prominent practitioner of free verse. The poetic quality of his work shows considerable ingenuity, and a key feature is his use of personification to create a humorous style. Collection of Humorous Free Verses by Kwang-Chung Yu contains the most representative examples of his work. As there are no existing studies on how Yu’s personification technique could be used for language education, the present study takes a qualitative approach to explore this topic. Of the verses featured in the collection, 88% of them use personification, and 102 personified themes were found overall. The discussion consists of four parts that serve as references for language education: (1) an analysis of examples representing the six categories of personified themes, (2) eight major reflection shortcuts for personification; (3) the association and application of eight types of situations for personification; and (4) a review of an online questionnaire and its positive results. The concluding section summarises Yu’s use of personification and presents a comprehensive model of personification for language education based on a pragmatic analysis. This model is a study of a master poet and is sure to be of interest to anyone who wants to know how personification techniques are crafted.


2012 ◽  
Vol 94 (887) ◽  
pp. 1089-1114 ◽  
Author(s):  
Claude Voillat

AbstractLarge companies can have both massively positive and massively negative impacts on communities, be it directly through their operations or indirectly through their influence on decision-makers. This is particularly true when business operations take place in conflict-affected or high-risk areas. Humanitarian organisations endeavouring to bring protection and/or assistance in these areas cannot, therefore, ignore these influential actors. Engagement with business actors – as well as with any other societal actor – should be framed within a clear rationale in order to deliver positive results. This article introduces the rationale that has been developed by the International Committee of the Red Cross (ICRC) and offers some examples of past engagement between the ICRC and business actors. It notes that occasions for humanitarian organisations to engage with business actors are likely to become more frequent in the coming years and argues that this trend, if properly managed, offers humanitarian organisations opportunities to leverage energies, know-how, and resources from the business sector for the benefit of the persons and communities that humanitarian organisations strive to protect and assist.


Author(s):  
Deni Ariyanti ◽  
Resi Yudhaningsih

<p><em>This research was conducted to find out how much the effectiveness and contribution of regional taxes on Regional Original Revenue (PAD), as well as to know how the relationship between local taxes and Kendal Regency Regional Revenue (PAD). Data collection methods used are interviews and documentation. The writing method used is description and exposition. The result of the discussion is that the level of local tax effectiveness is very effective with an average of 126.49%, the criteria for regional tax contribution to regional original income are quite good with an average of 30.47%, the results of regression analysis show positive results which means the growth in number Regional Tax revenues will result in the growth of Regional Original Income, and the results of the correlation analysis show that the regional tax on Kendal District Original Revenue (PAD) has a very strong relationship with a coefficient r of 0.89 so that if the local tax increases then the Local Revenue Kendal Regency will alsoincrease.</em><br /><em>Keywords: Regional Taxes, Regional Original Revenue, Effectiveness, and Contributions.</em></p>


2013 ◽  
Vol 22 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Jennifer Kent-Walsh ◽  
Cathy Binger

Abstract Researchers widely agree that working with communication partners is a critical component of any AAC intervention program. However, it can be difficult for clinicians to know how to structure this type of indirect intervention to do more than “tell” communication partners of individuals using AAC what they “should” be doing. The ImPAACT Program is one intervention program that has been documented to yield positive results for clients using AAC. The program involves a structured multistep approach to intervention that clinicians can customize for use across a range of communication partners, clients, and instructional contexts. In this article, we provide an overview of the program's instructional content, approach, and basis of evidence.


Author(s):  
G.D. Danilatos

The advent of the environmental SEM (ESEM) has made possible the examination of uncoated and untreated specimen surfaces in the presence of a gaseous or liquid environment. However, the question arises as to what degree the examined surface remains unaffected by the action of the electron beam. It is reasonable to assume that the beam invariably affects all specimens but the type and degree of effect may be totally unimportant for one class of applications and totally unacceptable for another; yet, for a third class, it is imperative to know how our observations are modified by the presence of the beam. The aim of this report is to create an awareness of the need to initiate research work in various fields in order to determine the guiding rules of the limitations (or even advantages) due to irradiation.


Author(s):  
G.F. Bastin ◽  
H.J.M. Heijligers ◽  
J.M. Dijkstra

For the calculation of X-ray intensities emitted by elements present in multi-layer systems it is vital to have an accurate knowledge of the x-ray ionization vs. mass-depth (ϕ(ρz)) curves as a function of accelerating voltage and atomic number of films and substrate. Once this knowledge is available the way is open to the analysis of thin films in which both the thicknesses as well as the compositions can usually be determined simultaneously.Our bulk matrix correction “PROZA” with its proven excellent performance for a wide variety of applications (e.g., ultra-light element analysis, extremes in accelerating voltage) has been used as the basis for the development of the software package discussed here. The PROZA program is based on our own modifications of the surface-centred Gaussian ϕ(ρz) model, originally introduced by Packwood and Brown. For its extension towards thin film applications it is required to know how the 4 Gaussian parameters α, β, γ and ϕ(o) for each element in each of the films are affected by the film thickness and the presence of other layers and the substrate.


ASHA Leader ◽  
2013 ◽  
Vol 18 (2) ◽  
Keyword(s):  
Know How ◽  

How to use your local know-how to get the media to pay attention.


2010 ◽  
Vol 11 (1) ◽  
pp. 21-24
Author(s):  
Nicole M. Mancini

Abstract At first, grant writing may look like a daunting task. You may ask yourself, “Is it really worth the time and effort?” With today's economic situation, teachers and therapists need ways to supplement their programs and grants provide such an opportunity. However, many of us do not know how to get started. After a few experiences and many lessons learned, I have come to enjoy researching and writing grants to supplement my students' learning. It is well worth the time and effort. This article provides information about a personal journey, lessons learned, and resources to get you started.


2015 ◽  
Vol 72 (9) ◽  
pp. 545-547 ◽  
Author(s):  
Christiane Brockes ◽  
Sabine Schmidt-Weitmann ◽  
Edouard Battegay
Keyword(s):  

Zusammenfassung. Das Messen und Sammeln von Gesundheits- und Fitnessdaten sowie die telemedizinische Beratung unterstützen die Eigenverantwortung und Selbstbestimmung des mündigen Bürgers in seiner Gesundheit und fördern das Patient-Empowerment. Da aber der Patient mit dem zunehmenden und weitläufigen Daten- und Informationsangebot mehr und mehr überfordert ist, benötigt er die Hilfe und den Ratschlag seines Arztes. Erfolgt eine telemedizinische Beratung, Betreuung oder Intervention, steht die sofortige individuelle medizinische Handlungskonsequenz als machbare Telemedizin Applikation im Vordergrund. Die Qualität steht und fällt mit der Aus-, Weiter- und Fortbildung bzw. dem telemedizinischem Know-how der involvierten Ärzte.


2011 ◽  
Vol 68 (9) ◽  
pp. 527-530
Author(s):  
Andreas Siegenthaler

Bei therapierefraktären chronischen Schmerzzuständen werden im Rahmen eines multimodalen Behandlungskonzeptes als Ergänzung zur medikamentösen, physio- und psychotherapeutischen Behandlung interventionelle Schmerztherapien durchgeführt. Diese beinhalten sowohl diagnostische als auch therapeutische Interventionen, welche entweder direkt gegen die Schmerz verursachende Struktur (z.B. intraartikuläre Steroidinfiltration) oder gegen die Schmerz leitenden Nervenstrukturen (z.B. Fazettennervenblockaden) gerichtet sind. Dabei wird zur Erhöhung der Präzision sowie Patientensicherheit die Nadelposition mittels radiologischer Bildgebung kontrolliert, wobei meistens die Durchleuchtung zur Anwendung kommt, bei entsprechender Indikation sowie Know-How sind auch Ultraschall- oder CT-kontrollierte Interventionen möglich. Im Folgenden werden die gängigen schmerztherapeutischen Interventionen, ohne Anspruch auf Vollständigkeit, näher vorgestellt.


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