The Detroit Research on Cancer Survivors (ROCS) study: A focus on outcomes after cancer in a racially diverse patient population.

2018 ◽  
Vol 36 (7_suppl) ◽  
pp. 177-177
Author(s):  
Jennifer Lynn Beebe-Dimmer ◽  
Terrance Lynn Albrecht ◽  
Julie J. Ruterbusch ◽  
Tara Baird ◽  
Theresa A. Hastert ◽  
...  

177 Background: Although we continue to make progress in reducing the incidence and mortality for most cancers in the United States, African Americans (AA) continue to experience higher cancer incidence rates and have worse survival than other populations. The causes of these poorer outcomes, from higher mortality to poorer quality of life, in AA cancer survivors are not well understood. The Detroit ROCS study was initiated to improve our understanding of the experience of AAs living with cancer. Methods: 1,000 AA and non-Hispanic white (NHW) patients with primary lung, female breast, prostate or colorectal cancer diagnosed on or after January 1, 2013, and/or treated at the Karmanos Cancer Institute in Detroit, MI were recruited to participate in a cohort study with planned follow-up for 4 years. At baseline, participants completed a web-based survey to gather information about their medical history, family history of cancer, treatment and medication use, behavioral risk factors and self-assessed quality of life. Statistical analyses were performed to examine racial differences in the distribution of patient characteristics including comorbid conditions, stage at diagnosis, first course treatment and reported health-related quality of life (HRQOL). Results: The majority of patients were AA (60%) and female (61%), with a median age at diagnosis of 60 years. AAs were older, more likely to report use of cigarettes and alcohol and report a greater number of comorbidities compared with NHW patients; they were less educated and less likely to be employed full time or married (all p-values < 0.001). AA patients reported poorer overall HRQOL compared with NHW patients (p-value < 0.001). Controlling for marital status and employment attenuated the observed racial differences in mean HRQOL scores across all measured domains. Conclusions: We observed significantly lower self-reported HRQOL among AA cancer survivors compared with NHW, which could be partially explained by differences in specific socioeconomic factors but interestingly, not the presence of multiple comorbidities. Future research efforts will evaluate the relative contribution of social and financial support to HRQOL in AAs.

2021 ◽  
Vol 12 (1) ◽  
pp. 102-105
Author(s):  
Amandeep R. Mahal ◽  
Laura D. Cramer ◽  
Elyn H. Wang ◽  
Shiyi Wang ◽  
Amy J. Davidoff ◽  
...  

2018 ◽  
Vol 12 (5) ◽  
pp. 1648-1664 ◽  
Author(s):  
Sabrina L. Dickey ◽  
Motolani E. Ogunsanya

The purpose of this integrative review was to explore the impact of prostate cancer (PCa) on the quality of life (QoL) and factors that contribute to the QoL for Black men with PCa. Prostate is recognized as the prevalent cancer among men in the United States. Compared to other men, Black men are diagnosed more frequently and with more advanced stages of PCa. Black men also experience disproportionately higher morbidity and mortality rates of PCa, among all racial and ethnic groups. The initial diagnosis of PCa is often associated with a barrage of concerns for one’s well-being including one’s QoL. As a result, men must contend with various psychosocial and physiological symptoms of PCa survivorship. Whittemore and Knafl’s integrative review method was utilized to examine empirical articles from the electronic databases of the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, PubMed, Project Muse, and Google Scholar. The time frame for the literature was January 2005 to December 2016. A synthesis of the literature yielded 18 studies that met the inclusion criteria for the integrative review. A conceptual framework that examined QoL among cancer survivors identified four domains that measured the QoL among Black PCa survivors: (a) physical; (b) psychological; (c) social; and (d) spiritual well-being. Social well-being was the dominant factor among the studies in the review, followed by physical, psychological, and spiritual. Results indicate the need for additional studies that examine the factors impacting the QoL among Black PCa survivors, using a theoretical framework so as to develop culturally appropriate interventions for Black PCa survivors.


2016 ◽  
Vol 34 (3_suppl) ◽  
pp. 203-203
Author(s):  
Samantha Carlson ◽  
Becky Jones ◽  
Linda Grossheim ◽  
Joseph Mirro

203 Background: The number of cancer survivors in the United States is increasing and estimated to exceed 13 million. Consequently, the quality of life of these patients and their family members has become a high priority. The best interventions to decrease distress, improve coping and quality of life for survivors are poorly understood but are becoming an important focus of research. We therefore, undertook a prospective pilot study using a questionnaire to measure the emotional impact of a play depicting cancer treatment on cancer survivors and their family members. This research project was reviewed and approved by the West Michigan Cancer Center Institutional Review Board (IRB). Methods: The emotional feelings and perceived levels of coping were measured and compared before and after the play. Statistical analyses of responses included chi-square and t-tests for continuous variables, or Fisher’s test or Wilcoxon’s test where parametric assumptions were not met. Results: A total of 60 survivors and 49 family members completed the research questionnaire. The most promising finding was that a majority of survivors and family members 51.0% (n = 50) felt they were coping better (p < 0.0001) after the play. Of the survivors, 73.0% said the play reflected their experiences and 78.0% felt it was helpful dealing with their emotions. Overall, 94.0% of those attending the play requested additional theater performances. Conclusions: Our preliminary data demonstrates that theater depicting cancer treatment has a strong emotional impact and potential therapeutic effects for cancer survivors and family members. Increased feelings of coping with the diagnosis occurred following the play. Attendees also felt less alone (59.5%) and more hopeful (53.4%) after the play.


2016 ◽  
Vol 159 (3) ◽  
pp. 535-543 ◽  
Author(s):  
Laura C. Pinheiro ◽  
Cleo A. Samuel ◽  
Katherine E. Reeder-Hayes ◽  
Stephanie B. Wheeler ◽  
Andrew F. Olshan ◽  
...  

2018 ◽  
Vol 36 (7_suppl) ◽  
pp. 122-122
Author(s):  
Yuly Andrea Remolina Bonilla ◽  
Alejandra Armengol Alonso ◽  
Raul Rogelio Trejo rosales

122 Background: Worldwide there is an increasing number of cancer survivors (CS); in the United States in 2016 there were more than 15 million CS and are predicted to increase to 20 million in 2026. In Mexico (GLOBOCAN 2012), new cancer cases were 148.000 and at least 69.000 will survive. Therefore, it is necessary to focus on cancer survivor’s quality of life (QOL) and its effects in social aspects. Methods: A cross-sectional study was performed including 205 CS with history of non-metastatic cancer (aged ≤65 years, ≥ 2 years from diagnosis and off chemo- or radiotherapy). The QOL-CS questionnaire developed by City of Hope Medical Center was used to measure QOL. Participants reported employment and marital status changes during or after cancer treatment. The aim of this study was to evaluate QOL in CS and its association with employment and marital status. A multivariate logistic regression analysis was conducted to estimate odds ratios (OR). Results: Of the 205 CS 70.2% were women and 29.8% men. Median age at the time of the study was 56 years. Median survival time from diagnosis was 83.6 months. 37.1% had history of invasive breast, 18% colorectal and 8.8% testicular cancers. Disease-related marital status changes presented in 15.6%, 26.8% lost or changed work and 36.6% decreased their work hours. Distress about initial diagnosis, cancer treatment, family and financial burden had the worst score in the QOL-CS. We found no differences in QOL between gender, income, age at diagnosis or type of tumor, but having received chemotherapy was associated with worst QOL (OR 7.33 CI 95% 1.99-26.96 p = 0.003) as well as self-reported neuropathy (OR 2.34 CI 95% 1.06-5.19 p = 0.032). Those with low QOL-CS scores (≤6) were more likely to have a disease-related change in employment (OR 2.34 CI 95% 1.19-4.61 p = 0.014). Disease-related marital status changes were higher in who experienced work status variations (OR 3.87 CI 95% 1.21-12.4 p = 0.023). Conclusions: this is one of the first studies in Mexican CS that associate QOL with relevant social roles. In this cohort having received chemotherapy has the greatest impact in QOL. CS with low QOL were more likely to have changes in employment and therefore, in the marital status.


2019 ◽  
Vol 18 (8) ◽  
pp. 720-728 ◽  
Author(s):  
Jennifer Viveiros ◽  
Brianna Chamberlain ◽  
Aminda O’Hare ◽  
Kristen A Sethares

Background: There has been growing interest in meditation techniques as an intervention in chronic disease populations. Little is known of the effect meditation practice has on outcomes among patients with heart failure. Purpose: To identify and examine current literature on meditation interventions on heart failure outcomes. Method: The review utilized methods described by Whittemore and Knafl. Three electronic databases were searched through March 2018. Terms used were “mindfulness OR meditation” and “heart failure” in combination, generating 58 articles after duplicates were removed. After inclusion and exclusion criteria were applied, six studies qualified for review, including four articles with samples from the United States and two with samples from Brazil and Sweden, respectively. Results: Among the six studies in the final sample, the total number of participants was 320 heart failure patients. Interventional design and length varied among the studies, and 20 different dependent variables were identified. This study distinguished four categories of outcome measures with significant findings: psychosocial, biophysical, quality of life and heart failure symptom burden. Compared with controls meditation practice significantly improved depression ( p<.05), social support ( p<.05), biophysical factors and quality of life ( p<.05), in addition to reducing heart failure symptom burden. Across-study comparisons were limited due to variation in intervention definitions and designs. Additionally, the intervention dose and reporting method varied, limiting comparisons. The sample size in five out of six studies was fewer than 50 participants. Over 20 different measures were used across the six studies to measure outcome variables. Conclusion: Meditation may offer a patient-driven practice to reduce heart failure symptoms as well as improve psychosocial wellness and quality of life. Future research among heart failure patients should include the following: rigorous definition of meditation interventions, consistency in intervention characteristics, larger controlled trials, and standardized outcome instruments.


2006 ◽  
Vol 24 (32) ◽  
pp. 5149-5153 ◽  
Author(s):  
John Z. Ayanian ◽  
Paul B. Jacobsen

The United States devotes substantial resources to understanding the etiologies of cancer and improving treatments, but much less research has focused on the needs of cancer survivors after they have completed active treatment. This article augments findings from the Institute of Medicine about cancer survivorship research and ways to enhance quality of life and quality of care. Studies of cancer survivors should focus on mechanisms and risk factors for impaired quality of life and evaluate interventions to improve this domain. Research to improve quality of care should concentrate on survivorship care plans, surveillance tests, respective roles of primary and specialty care, and performance measures related to survivorship care. Opportunities to expand research on cancer survivors include clinical trials, large cohort studies, cancer registries, and national surveys. Research to understand the needs of cancer survivors will provide a foundation for effective programs to meet these needs.


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