Immobilized Cell Receptor Ligands and Immobilized Cells

1985 ◽  
Vol 50 (10) ◽  
pp. 2122-2133 ◽  
Author(s):  
Jindřich Zahradník ◽  
Marie Fialová ◽  
Jan Škoda ◽  
Helena Škodová

An experimental study was carried out aimed at establishing a data base for an optimum design of a continuous flow fixed-bed reactor for biotransformation of ammonium fumarate to L-aspartic acid catalyzed by immobilized cells of the strain Escherichia alcalescens dispar group. The experimental program included studies of the effect of reactor geometry, catalytic particle size, and packed bed arrangement on reactor hydrodynamics and on the rate of substrate conversion. An expression for the effective reaction rate was derived including the effect of mass transfer and conditions of the safe conversion-data scale-up were defined. Suggestions for the design of a pilot plant reactor (100 t/year) were formulated and decisive design parameters of such reactor were estimated for several variants of problem formulation.


2008 ◽  
Vol 123 (10) ◽  
pp. 2343-2353 ◽  
Author(s):  
Sonja Textor ◽  
Matthias Dürst ◽  
Lars Jansen ◽  
Rosita Accardi ◽  
Massimo Tommasino ◽  
...  

Author(s):  
Suchata Kirdponpattara ◽  
Santi Chuetor ◽  
Malinee Sriariyanun ◽  
Muenduen Phisalaphong

Cell immobilization technique was applied in this study in order to examine effect of immobilized Pichia stipitis TISTR5806 on bioethanol production. Water hyacinth (WH) and thin-shell silk cocoon (CC) were used as cell carriers. Characteristics of the cell carriers were examined to explain the mechanism of bioethanol production. Carrier sizes and weights were optimized to improve bioethanol production. Moreover, stabilities of immobilized cells and carriers were evaluated. Because of high porosity, high surface area and good swelling ability of WH, cell immobilized on 1 g WH with 1 cm length produced the highest ethanol concentration at 13.3 g/L. Five cycles of a repeated batch of immobilized cell (IC) system on WH showed stable performance in ethanol production (8.2–10.4 g/L) with large numbers of the immobilized cells. The interaction between the immobilized cells and the WH surface were discovered.


2019 ◽  
Vol 19 (10) ◽  
pp. 2692-2704 ◽  
Author(s):  
Johanna Egelkamp ◽  
Evgeny Chichelnitskiy ◽  
Jenny F. Kühne ◽  
Franziska Wandrer ◽  
Kerstin Daemen ◽  
...  

Immunity ◽  
1996 ◽  
Vol 5 (2) ◽  
pp. 125-135 ◽  
Author(s):  
Joshua D Rabinowitz ◽  
Craig Beeson ◽  
Christoph Wülfing ◽  
Keri Tate ◽  
Paul M Allen ◽  
...  

2018 ◽  
Vol 34 (3) ◽  
pp. 385-408 ◽  
Author(s):  
Zakaria Al-Qodah ◽  
Mohammad Al-Shannag ◽  
Mamdouh Al-Bosoul ◽  
Ivan Penchev ◽  
Hamed Al-Ahmadi ◽  
...  

Abstract This review focuses on the performance of immobilized cell bioreactors utilizing a magnetic field. These reactors utilized immobilized cells on magnetic particles or beads as the solid phase. All published research papers dealing with the performance of immobilized cell bioreactors utilizing a magnetic field from the early 1960s to the present time were considered and analyzed. It was noted that many microorganisms such as Saccharomyces cerevisiae were immobilized on different supports in these reactors. These papers used the magnetic field for several purposes, mainly for the stabilization of magnetic particles to prevent their washout from the column while operating with relatively high substrate flow rates to enhance mass transfer processes. It was observed that most publications used an axial magnetic field. In addition, most of the magnetic particles were prepared by entrapment. Some comments are presented at the end of the review which show the gaps in this promising application.


2014 ◽  
Vol 5 (5) ◽  
pp. 577-585 ◽  
Author(s):  
Jie Pan ◽  
Julie Palmateer ◽  
Timothy Schallert ◽  
Madison Hart ◽  
Arushi Pandya ◽  
...  

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