Relationship between maternal bone biomarkers and fetal adiposity through normal pregnancy

2021 ◽  
Author(s):  
George Mastorakos ◽  
Dimosthenis Maliopoulos ◽  
Spyridoula Kasioni ◽  
Alexandra Bargiota ◽  
Thomas Μ Barber ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Birth Weight ◽  
Bone Markers ◽  
Subcutaneous Fat ◽  
Normal Pregnancy ◽  
Abdominal Circumference ◽  
Sagittal Abdominal Diameter ◽  
Sagittal Diameter ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

Abstract Purpose To examine the association of maternal bone markers (sclerostin, sRANKL, osteocalcin, 25OHD3) with fetal intra-abdominal and subcutaneous adipose tissue deposition and birthweight during normal pregnancy. Methods One hundred pregnant women (aged 30.4±5.6 years, mean±SD) with pre-pregnancy BMI=24.1±4.6 kg/m² were seen prospectively during each trimester. At each visit they were submitted to anthropometric measurements, a fasting blood sampling, a 75gr oral glucose tolerance test (OGTT) and a fetal ultrasonogram. At birth, neonates had birth weight measurement. Results In the 2 nd trimester maternal sclerostin concentrations correlated positively with fetal abdominal circumference and birth weight; maternal sRANKL concentrations correlated positively with fetal abdominal subcutaneous fat thickness, sagittal abdominal diameter and abdominal circumference. Fetuses born to mothers with greater (>254 ng/mL) compared to fetuses born to mothers with lower (≤254 ng/mL) sRANKL concentrations had greater abdominal circumference, sagittal diameter and abdominal subcutaneous fat thickness. Maternal serum sclerostin concentrations were the best positive predictors of birth weight. In the 3 rd trimester maternal sclerostin concentrations correlated positively with fetal sagittal abdominal diameter; maternal sRANKL concentrations positively correlated with fetal abdominal circumference and fetal abdominal sagittal diameter. Conclusions Maternal bone markers sclerostin and sRANKL may relate with fetal intra-abdominal adipose tissue deposition through direct or indirect unknown as yet mechanisms contributing thus, to birthweight.

The effects of food intake in gestation on sows lactating for 14 days

1983 ◽  
Vol 37 (1) ◽  
pp. 25-31 ◽  
Author(s):  
N. Walker
Keyword(s):  
Growth Rate ◽  
Birth Weight ◽  
Food Intake ◽  
Growth Rates ◽  
Subcutaneous Fat ◽  
Live Weight ◽  
Weaning Weight ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

ABSTRACTNinety-two gilts in replicates of four littermates were mated at puberty at a mean live weight and age of 95 kg and 191 days respectively. The littermates were allocated at random to one of four food allowances (kg/day) during four successive gestations: (A) 1·5, (B) 2·0 in parity 1 followed by 1·5 in subsequent parities, (C) 20 and (D) 2·5. A diet calculated to contain 12·7 MJ digestible energy per kg was fed throughout gestation, the 2-week lactation and from weaning to conception.The numbers of sows which conceived at parity 5 when the experiment terminated were 10, 12, 13 and 16 for treatments A to D respectively. Sow live weight at conception differed significantly (P < 0·01) from parity 2 onwards: the maximum live weights of sows on treatments A and B did not exceed 130 to 135 kg, but the live weights of sows on treatment D continued to increase to reach 195 kg at the end of the experiment. The in vivo skin plus subcutaneous fat thickness at the P2 location differed significantly (P < 0·001) between treatments from parity 2 onwards, decreasing by 3 mm in treatment A and increasing by 6 mm in treatment D from the start of the experiment to conception at parity 4. The interval from weaning to conception was significantly (P < 0·05) lower in treatment B in parity 2. This was the only significant effect and was contrary to the tendency for the interval to increase as the food allowance in gestation was decreased. The numbers of pigs born alive, stillborn or weaned (including fostered pigs) were not significantly affected by treatment. Birth weight and post-natal growth rates were significantly (P < 0·05) increased after parity 1 as gestation food allowance increased, with the exception of the post-natal growth rate in parity 3. Overall birth weight was increased by 018 kg per pig and weaning weight by 0·93 kg per pig on treatment D compared with treatment A.

Correlates of visceral and subcutaneous fat thickness in non-diabetic obese and morbidly obese patients

2014 ◽  
Author(s):  
Ozen Oz Gul ◽  
Murat Pekgoz ◽  
Sumeyye Gullulu ◽  
Soner Cander ◽  
Ahmet Tutuncu ◽  
...  
Keyword(s):  
Subcutaneous Fat ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

The Use of Ultrasonic Measurements on Subcutaneous Fat Thickness in Breeding of Japanese Shorthorn Cattle

1988 ◽  
Vol 59 (4) ◽  
pp. 335-343
Author(s):  
Yoshitaka NAGAMINE ◽  
Takashi HAYASHI ◽  
Hiroshi SATO ◽  
Akira NISHIDA ◽  
Shigeki KOMATSU
Keyword(s):  
Subcutaneous Fat ◽  
Ultrasonic Measurements ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

Subcutaneous fat thickness at slaughter in castrated and non-castrated Santa Inês and Dorper lambs and its influence on meat and carcass quality

2021 ◽  
pp. 104694
Author(s):  
Francisco Fernandes Junior ◽  
Amanda de Freitas Pena ◽  
Fernando Augusto Grandis ◽  
Natalia Albieri Koritiaki ◽  
Fabíola Cristine de Almeida Rego ◽  
...  
Keyword(s):  
Subcutaneous Fat ◽  
Carcass Quality ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness ◽  
Santa Inês

Abdominal Laser Lipolysis Using a Microprocessor-Controlled Robotic Arm with Non-Contact Heating and Cooling

2021 ◽  
Author(s):  
Thomas Fiala
Keyword(s):  
Cooling System ◽  
Subcutaneous Fat ◽  
Treatment Protocol ◽  
Abdominal Fat ◽  
Abdominal Circumference ◽  
Ordinal Scale ◽  
Robotic Arm ◽  
Ultrasound Measurement ◽  
Fat Thickness ◽  
The Mean

Abstract Background A novel FDA-cleared device uses a 1064 nm laser to non-invasively induce apoptosis for lipolysis of subcutaneous abdominal fat while maintaining comfortable skin temperatures with a proprietary jet cooling system (eon ®, Dominion Aesthetic Technologies, Inc.; San Antonio, TX). A programmable articulated robotic arm moves the treatment head without any subject contact, maintaining an appropriate three-dimensional treatment path, compensating for patient movement. Objectives The goal of this prospective, single center, open-label study was to demonstrate the safety and effectiveness of this device for reducing subcutaneous abdominal fat using an updated power delivery curve. Methods Male and female subjects with Fitzpatrick skin types I-VI (N=26) were treated. Four abdominal zones up to 150 cm 2 each, customized in size and location for body habitus were treated. Each zone underwent a single 20-minute treatment session. Follow-up visits occurred after 6 and 12 weeks. Using a standardized protocol, ultrasound measurement of subcutaneous abdominal fat thickness, abdominal circumference, reported patient satisfaction and digital images were obtained. Results The mean treatment area was 378.5 cm 2. At Week 12, there was a 21.6% mean reduction in abdominal subcutaneous fat thickness and a 4.1-cm (1.6-inch) mean reduction in abdominal circumference. Most subjects (84.6%) were satisfied or very satisfied with their results. The mean pain score was 2.5 on an 11-point ordinal scale. There were no non-responders. Only two adverse events were noted: mild transient erythema (n=1, 3.8%) and localized subcutaneous firmness (n=1, 3.8%) which resolved without intervention within 12 weeks. Conclusions This contact-free device is safe and effective for reducing subcutaneous abdominal fat and represents an improvement on the prior treatment protocol.

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