scholarly journals Clinical Characteristics and Postoperative Outcomes of Primary Aldosteronism in the Elderly

2018 ◽  
Vol 103 (10) ◽  
pp. 3620-3629 ◽  
Author(s):  
Masao Takeda ◽  
Koichi Yamamoto ◽  
Hiroshi Akasaka ◽  
Hiromi Rakugi ◽  
Mitsuhide Naruse ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Clinical Characteristics ◽  
The Elderly ◽  
Postoperative Outcomes

scholarly journals Epidemiological and clinical characteristics of the first 500 confirmed COVID-19 inpatients in a tertiary infectious disease referral hospital in Manila, Philippines

2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Kristal An Agrupis ◽  
Chris Smith ◽  
Shuichi Suzuki ◽  
Annavi Marie Villanueva ◽  
Koya Ariyoshi ◽  
...  
Keyword(s):  
Healthcare Workers ◽  
Clinical Characteristics ◽  
Age Groups ◽  
The Elderly ◽  
Underlying Disease ◽  
The Philippines ◽  
Referral Hospital ◽  
Limited Data ◽  
Metro Manila ◽  
Related Mortality

Abstract Background The Philippines has been one of the most affected COVID-19 countries in the Western Pacific region, but there are limited data on COVID-19-related mortality and associated factors from this setting. We aimed to describe the epidemiological and clinical characteristics and associations with mortality among COVID-19-confirmed individuals admitted to an infectious diseases referral hospital in Metro Manila. Main text This was a single-centre retrospective analysis including the first 500 laboratory-confirmed COVID-19 individuals admitted to San Lazaro Hospital, Metro Manila, Philippines, from January to October 2020. We extracted clinical data and examined epidemiological and clinical characteristics and factors associated with in-hospital mortality. Of the 500 individuals, 133 (26.6%) were healthcare workers (HCW) and 367 (73.4%) were non-HCW, with HCW more likely presenting with milder symptoms. Non-HCW admissions were more likely to have at least one underlying disease (51.6% vs. 40.0%; p = 0.002), with hypertension (35.4%), diabetes (17.4%), and tuberculosis (8.2%) being the most common. Sixty-one (12.2%) died, comprising 1 HCW and 60 non-HCW (0.7% vs. 16.3%; p < 0.001). Among the non-HCW, no death occurred for the 0–10 years age group, but deaths were recorded across all other age groups. Compared to those who recovered, individuals who died were more likely to be older (p < 0.001), male (p = 0.015), report difficulty of breathing (p < 0.001), be HIV positive (p = 0.008), be intubated (p < 0.001), categorised as severe or critical (p < 0.001), have a shorter mean hospital stay (p < 0.001), or have an additional diagnosis of pneumonia (p < 0.001) or ARDS (p < 0.001). Conclusion Our analysis reflected significant differences in characteristics, symptomatology, and outcomes between healthcare and non-healthcare workers. Despite the unique mix of cohorts, our results support the country’s national guideline on COVID-19 vaccination which prioritises healthcare workers, the elderly, and people with comorbidities and immunodeficiency states.

scholarly journals Comparing the Clinical Characteristics and Mortality of Residential and Non-Residential Older People with COVID-19: Retrospective Observational Study

2022 ◽  
Vol 19 (1) ◽  
pp. 483
Author(s):  
Francesc X. Marin-Gomez ◽  
Jacobo Mendioroz-Peña ◽  
Miguel-Angel Mayer ◽  
Leonardo Méndez-Boo ◽  
Núria Mora ◽  
...  
Keyword(s):  
Risk Factors ◽  
Electronic Medical Records ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Fold Increase ◽  
The Elderly ◽  
Health Administration ◽  
Epidemic Outbreak ◽  
Risk Of Death ◽  
Using Data

Nursing homes have accounted for a significant part of SARS-CoV-2 mortality, causing great social alarm. Using data collected from electronic medical records of 1,319,839 institutionalised and non-institutionalised persons ≥ 65 years, the present study investigated the epidemiology and differential characteristics between these two population groups. Our results showed that the form of presentation of the epidemic outbreak, as well as some risk factors, are different among the elderly institutionalised population with respect to those who are not. In addition to a twenty-fold increase in the rate of adjusted mortality among institutionalised individuals, the peak incidence was delayed by approximately three weeks. Having dementia was shown to be a risk factor for death, and, unlike the non-institutionalised group, neither obesity nor age were shown to be significantly associated with the risk of death among the institutionalised. These differential characteristics should be able to guide the actions to be taken by the health administration in the event of a similar infectious situation among institutionalised elderly people.

scholarly journals Clinical Characteristics and Management of Angioedema Attacks in Polish Adult Patients with Hereditary Angioedema Due to C1-Inhibitor Deficiency

2021 ◽  
Vol 10 (23) ◽  
pp. 5609
Author(s):  
Katarzyna Piotrowicz-Wójcik ◽  
Małgorzata Bulanda ◽  
Aldona Juchacz ◽  
Joanna Jamróz-Brzeska ◽  
Jacek Gocki ◽  
...  
Keyword(s):  
Hereditary Angioedema ◽  
Clinical Characteristics ◽  
Rescue Medication ◽  
Real Life ◽  
The Elderly ◽  
C1 Inhibitor ◽  
Self Administration ◽  
C1 Inhibitor Deficiency ◽  
Cross Sectional ◽  
Delay In Diagnosis

Hereditary angioedema (HAE) due to C1-inhibitor (C1-INH) deficiency is a rare disease characterized by recurrent swellings. This study aims to determine (i) the clinical characteristics of the HAE patient population from Poland, and (ii) real-life patients’ treatment practices. A cross-sectional study involved 138 adult HAE patients (88 females, 50 males) treated in six regional HAE centers in Poland. Consecutive patients during routine follow-up visits underwent a structured medical interview on the clinical characteristics of the course and treatment of HAE attacks within the last six months. A total of 118 of 138 patients was symptomatic. They reported in total 2835 HAE attacks predominantly peripheral and abdominal, treated with plasma-derived C1-INH (61.4%), icatibant (36.7%) and recombinant C1-INH (1.9%). An amount of 116 patients carried the rescue medication with them while traveling, and 74 patients self-administrated on demand treatment. There were twice as many symptomatic women (n = 78) as there were men (n = 40). Women treated their HAE attacks significantly more often than men. Older patients (≥65 years) reported a longer delay in diagnosis, and practiced the self-administration of rescue medication less frequently in comparison to other patients. Clinical features of the surveyed population are similar to other European, but not Asian, HAE patient groups. Self-administration still remains an unmet medical need. Some distinct HAE patients may require special attention due to the severe course of the disease (females) or a delay in diagnosis (the elderly).

Impact of Tuberculosis in Elderly Population

2018 ◽  
pp. 326-338
Author(s):  
Gagan Chooramani ◽  
Pooja Singh
Keyword(s):  
Clinical Characteristics ◽  
Elderly Population ◽  
The Elderly ◽  
World Health ◽  
Tuberculosis Patients ◽  
Disease Outcomes ◽  
Age Related ◽  
Health Organization ◽  
The Impact ◽  
Poor Memory

The World Health Organization has declared that the spread of tuberculosis is a global emergency. Despite the implementation of strong tuberculosis-control initiatives by WHO, this highly infectious disease continues to affect all vulnerable populations, including the elderly population. Adverse social factors and poor living conditions also affect the elderly much more than the young. The clinical characteristics of tuberculosis in older adults can be unusual and may be confused with age-related illnesses. Various factors related to old age can also cause complications in the diagnosis, treatment, and disease outcomes for tuberculosis patients. The contributory factors may be poor memory, deafness, mental confusion, or impairment of speech. In addition, therapy for tuberculosis in elderly individuals is challenging because of the increased incidence of adverse drug reactions. Hence, understanding the impact of these substantial aspects will help to overcome the problem of tuberculosis in the elderly population.

Acute Heart Failure in the Elderly: Differences in Clinical Characteristics, Outcomes, and Prognostic Factors in the VERITAS Study

2015 ◽  
Vol 21 (3) ◽  
pp. 179-188 ◽  
Author(s):  
Marco Metra ◽  
Gad Cotter ◽  
Jill El-Khorazaty ◽  
Beth A. Davison ◽  
Olga Milo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Prognostic Factors ◽  
Acute Heart Failure ◽  
Clinical Characteristics ◽  
The Elderly

The association of preoperative delirium with postoperative outcomes following hip surgery in the elderly

2020 ◽  
Vol 60 ◽  
pp. 28-33 ◽  
Author(s):  
Shubham Agrawal ◽  
Robby Turk ◽  
Brittany N. Burton ◽  
Jerry Ingrande ◽  
Rodney A. Gabriel
Keyword(s):  
The Elderly ◽  
Postoperative Outcomes ◽  
Hip Surgery ◽  
Surgery In The Elderly

scholarly journals Preoperative Cognitive Dysfunction Is Related to Adverse Postoperative Outcomes in the Elderly

2012 ◽  
Vol 215 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Thomas N. Robinson ◽  
Daniel S. Wu ◽  
Lauren F. Pointer ◽  
Christina L. Dunn ◽  
Marc Moss
Keyword(s):  
Cognitive Dysfunction ◽  
The Elderly ◽  
Postoperative Outcomes
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