scholarly journals Prehospital Management of Acute Addison Disease: Audit of Patients Attending a Referral Hospital in a Regional Area

2019 ◽  
Vol 3 (12) ◽  
pp. 2194-2203 ◽  
Author(s):  
Thomas Goubar ◽  
David J Torpy ◽  
Shaun McGrath ◽  
R Louise Rushworth

Abstract Context Adrenal crisis (AC) causes morbidity and mortality in patients with Addison disease [primary adrenal insufficiency (PAI)]. Patient-initiated stress dosing (oral or parenteral hydrocortisone) is recommended to avert ACs. Although these should be effective, the continued incidence of ACs remains largely unexplained. Methods Audit of all attendances between 2000 and 2017 of adult patients with treated PAI to one large regional referral center in New South Wales, Australia. Measurements were those taken on arrival at hospital. Results There were 252 attendances by 56 patients with treated PAI during the study period. Women comprised 60.7% (n = 34) of the patients. The mean age of attendees was 53.7 (19.6) years. Nearly half (45.2%, n = 114) of the patients had an infection. There were 61 (24.2%) ACs diagnosed by the treating clinician. Only 17.9% (n = 45) of the hospital presentations followed any form of stress dosing. IM hydrocortisone was used prior to presentation 7 (2.8%) attendances only. Among patients with a clinician-diagnosed AC, only 32.8% (n = 20) had used stress dosing before presentation. Vomiting was reported by 47.6% (n = 120) of the patients but only 33 (27.5%) of these attempted stress dosing and 5 patients with vomiting used IM hydrocortisone. The number of prior presentations was an independent predictor of use of stress doses [1.05 (1.01, 1.09)]. Conclusion Dose-escalation strategies are not used universally or correctly by unwell patients with PAI; many patients do not use IM or subcutaneous hydrocortisone injections. Previous hospital treatment increases the likelihood of stress dosing, and hospital attendance offers the opportunity for reinforcement of prevention strategies.

2017 ◽  
Vol 25 (5) ◽  
pp. 456-459
Author(s):  
Kevin Rourke ◽  
Coralie J Wilson

Objectives: To determine if adolescents perceive community-based exercise as beneficial to their well-being and in what ways. Methods: A New South Wales Police Citizens Youth Club ran a four-week fitness course. The classes involved: 1) sports including basketball and soccer, 2) non-contact boxing drills, and 3) games, both team games such as dodgeball and non-team games such as line tag. Parental consent to offer a survey at the completion of the course was requested during registration. The survey was the Warwick Edinburgh Mental Well-being Scale; it was minimally modified to measure perceived benefit to mental well-being instead of actual benefit. Results: Thirty-one high school adolescents, ages 13–18, completed the survey. As a group, participants reported that they believed their well-being had improved after the course. The mean score for each survey item showed an improvement in every area of mental well-being for this sample of adolescents. Thirty-two per cent of adolescents reported having less energy. Survey scores indicated a statistically significant improvement in perceived well-being ( p<0.0001). Conclusions: The results of this study suggest that four weeks of community-based exercise improves perceived mental well-being in adolescent participants.


1998 ◽  
Vol 46 (2) ◽  
pp. 153 ◽  
Author(s):  
Damon L. Oliver

The regent honeyea ter, Xanthomyza phrygia, is an endangered woodland bird whose range and population size have decreased in the last thirty years. Suggested reasons for this decline include abnormal breeding behaviour, poor reproductive output, and excessive inter- and intra-specific aggression. This study investigated the breeding behaviour and aggressive interactions of regent honeyeaters during the nest construction, incubation, nestling, and fledgling stages in two consecutive breeding seasons in the Bundarra–Barraba region near Armidale, New South Wales. The female was entirely responsible for nest construction and incubation, which is typical of many honeyeaters. Both parents fed the nestlings, and at a similar rate, although only the female brooded chicks on the nest. Both parents fed the fledglings. The mean frequency at which nestlings (23 times per hour) and fledglings (29 times per hour) were fed is the highest published rate of any non-cooperative honeyeater. Breeding males were involved in significantly more aggressive interactions with conspecifics and other nectarivores than were females, although the overall percentage of day-time spent in aggression for both sexes was low (2.5%). It appears that abnormal breeding behaviour, poor reproductive effort, or excessive aggression are not experienced by this species in northern New South Wales, and that other factors are likely to be responsible for its current low population level.


1994 ◽  
Vol 34 (1) ◽  
pp. 33 ◽  
Author(s):  
GM Lodge

Burrs were collected from paddocks on 3 properties in northern New South Wales where the age of the Trifolium subterraneum var. brachycalycinum cv. Clare swards varied from 19 to 28 years. At 1 site burrs were also sampled from swards sown 2 and 10 years previously. Twenty seedlings from these burrs and 20 plants of certified cv. Clare were grown as spaced plants in a nursery. These were assessed for vegetative and floral characters, flowering time, number of seeds per burr, seed weight, and percentage hardseed after storage at 25/25�C for 6 months and 25/45�C for a further 6 months. For most plants the mean number of days from sowing to first flower was similar to that of Clare. Compared with the naturalised strains, Clare had the lowest (P<0.05) mean number of seeds per burr: about 25% below the mean of the strains (2.7 seeds per burr). While the lowest mean seed weights of the strains were not significantly different from those of Clare, the seed weights of plants from 3 sites were higher (P<0.05) than those of Clare. After storage for either 6 or 12 months, hardseed levels were also lowest (P<0.05) for Clare. Plants from the 2-year-old sward had the same median number of seeds per burr (2.0) as Clare. As sward age increased, the median number of seeds per burr increased to 2.8. Hardseed percentages were lowest for plants of Clare and for those from the 2-year-old sward after 6 months, and for Clare after 12 months. These studies indicated the presence of divergent strains in old swards of Clare in a summer rainfall environment. Natural selection among variability within Clare is the most likely reason for the development of these strains in an environment marginal for the long-term persistence of this softseeded cultivar. Although strains had the same vegetative and floral markings as Clare, differences in ecologically important characters such as number of seeds per burr, seed weight, and hardseededness may result in plants that are better adapted to the environment in which they evolved. From these studies 23 plants of T. subterraneum var. brachycalycinum were selected for further evaluation.


1967 ◽  
Vol 7 (24) ◽  
pp. 7 ◽  
Author(s):  
P McInnes ◽  
TJ Grainger ◽  
MD Smith

Data are presented on the recovery and reproductive performance of 2 1/2-year-old maiden Merino ewes after a prolonged period of undernutrition. The 217 sheep had been hand-fed on a submaintenance ration in pen feeding trials at Glenfield, New South Wales. During the seven months of the trials they had lost 6 kg (28 to 22 kg) body weight. They were transported to Condobolin in south-western New South Wales, divided into two treatment groups and run on good quality pastures. One group was joined immediately (May 1959) and again ten months later, and the other group was mated after six months at Condobolin (in October 1959) and again 12 months later. The ewes recovered rapidly. The mean weight of both groups had reached 30 kg within six weeks and 40 kg within six months. In the first year 73 of the 100 May-mated ewes bore lambs, but only 38 of these lambs were weaned. Ewes bearing lambs had a higher body weight at the start of joining and gained more during joining than the barren ewes. At the other three joinings (October 1959, May 1960, October 1960) lambing percentage was from 86-89 and weaning percentage from 62-69-both normal for the district. The proportion of twin lambs (3-6 per cent) was low. Wool weight in 1959 was not affected by time of mating or by pregnancy.


1978 ◽  
Vol 1 (2) ◽  
pp. 167
Author(s):  
VR Squires

In order to assess the current level of stock watering facilities on pastoral properties within the western Riverina district of New South Wales and to relate this information to paddock size and vegetation type, large of areas of land (785,000 ha) within the region were surveyed. Paddock boundaries and the location of watering points were plotted. Watering points were classified as to type. Three broad vegetation types were represented: chenopod shrublands (Atriplex and Maireana spp.) degraded grasslands (Stipal Danthonia spp.), and mallee woodlands (Eucalyptus socinlis F. Meull., E, oleosa, F. Meull.) Size of paddocks was related to the dominant vegetation type. On the degraded grasslands in the eastern part of the study area the mean paddock size was 746 ha; on the chenopod shrublands it was 780 ha, and in the Malleedominated areas it was 1,553 ha. The number of permanent watering points per paddock varied from one to four. Less than half the paddocks (43%) had fresh water available as well as saline waters from sub-artesian bores. Almost half the paddocks (47%) were so large, or the watering points so positioned, that the sheep would need to walk more than 3 km to reach the most remote parts of the paddock when temporary waters had dried up. Overall 18% of the land in the non- mallee areas was more than 3 km from permanent water. Therefore the majority of the land could be used in all seasons. Generally the central and northern Riverina district is adequately watered. It would be uneconomic to supply permanent water in the mallee woodlands. In some paddocks in the chenopod dominated area extra watering points may be justified.


1978 ◽  
Vol 1 (2) ◽  
pp. 106 ◽  
Author(s):  
DL Michalk ◽  
PK Herbert

A study of the density and basal diameter of Chloris acicularis Lindl. (syn. Enteropogon acicularis (LindlJLazar. - curly windmill grass) and C. truncata R. Br. (windmill grass) was made at two stocking rates over a period of eight years. The propor- tion of ground covered by these Chloris species varied widely with season, and to a lesser extent with grazing pressure. The density of both species increased in good seasons, while the mean diameter decreased because of the number of new seedlings. Although C. truncata seedlings were more numerous in good seasons, they did not survive as well as did C. acicularis seedlings during prolonged dry periods.


1984 ◽  
Vol 32 (5) ◽  
pp. 631 ◽  
Author(s):  
RJ Whittington ◽  
TR Grant

Blood was collected from a bill sinus of nine conscious adult platypuses, Ornithorhynchus anatinus, caught in south-eastem New South Wales. Sexual dimorphisms were not found in the haematological and serum biochemical values measured. Results were compared with those obtained earlier from anaesthetized platypuses: ether anaethesia did not affect red cell parameters and the majority of biochemical values measured. It did, however, cause significant leukocytosis due to neutrophilia and monocytosis. The mean total leukocyte count in conscious platypuses was 28.63 X 10*9.1-�. The unusually high urea levels and low creatinine levels found in anaesthetized platypus were confirmed in this study (31.5 mmol.l-� and 26 �mol.l-� respectively). High values for erythrocyte count (9.96 X 10*12.l-�), packed cell volume (0.491.l-�) and haemoglobin (190 g.l-�) were found in conscious platypuses, confirming earlier findings and supporting the view that the erythrocyte parameters of the platypus show significant adaptations to hypoxia.


1967 ◽  
Vol 15 (6) ◽  
pp. 1163 ◽  
Author(s):  
WH Ewers

A morph-frequency cline and a size cline are described for the snail Velacumantus australis. The frequency of a white-banded form decreases clinally with latitude South. Living populations from Queensland and northern New South Wales have frequencies between 7 and 18% whereas all populations from southern New South Wales and eastern Victoria, except those from Lake Illawarra, have frequencies between 2 and 5%. The frequency in Port Phillip Bay is less than 0.1%. The frequency in a sample from Swan River, Western Australia, was 9.1% about the same as in samples from localities of the same latitude on the eastern coast of Australia. The frequency in most fossil samples was similar to that in nearby living populations. The mean length of populations from the eastern states increases clinally with increase in latitude South, although there are some irregular fluctuations between adjacent populations which are probably influenced by population density.


Soil Research ◽  
2018 ◽  
Vol 56 (8) ◽  
pp. 780 ◽  
Author(s):  
Mark Conyers ◽  
Beverley Orchard ◽  
Susan Orgill ◽  
Albert Oates ◽  
Graeme Poile ◽  
...  

Estimating the likely variance in soil organic carbon (OC) at the scale of farm fields or smaller monitoring areas is necessary for developing sampling protocols that allow temporal change to be detected. Given the relatively low anticipated soil OC sequestration rates (&lt;0.5 Mg/ha.0.30 m/year) for dryland agriculture it is important that sampling strategies are designed to reduce any cumulative errors associated with measuring soil OC. The first purpose of this study was to evaluate the spatial variation in soil OC and nitrogen (N), in soil layers to 1.50 m depth at two monitoring sites (Wagga Wagga and Yerong Creek, 0.5 ha each) in southern New South Wales, Australia, where crop and pasture rotations are practiced. Four variogram models were tested (linear, spherical, Gaussian and exponential); however, no single model dominated across sites or depths for OC or N. At both sites, the range was smallest in surface soil, and on a scale suggesting that sowing rows (stubble) may dominate the pattern of spatial dependence, whereas the longer ranges appeared to be associated with horizon boundaries. The second purpose of the study was to obtain an estimate of the population mean with 1%, 5% and 10% levels of precision using the calculated variance. The number of soil cores required for a 1% precision in estimation of the mean soil OC or N was impractical at most depths (&gt;500 per ha). About 30 soil cores per composite sample to 1.50 m depth, each core being at least 10 m apart, would ensure at least an average of 10% precision in the estimation of the mean soil OC at these two sites, which represent the agriculture of the region.


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