Essential Tremor: Five New Things

2021 ◽  
pp. 10.1212/CPJ.0000000000001145
Author(s):  
Abhishek Lenka ◽  
Sanjay Pandey
Keyword(s):  
Magnetic Resonance ◽  
Essential Tremor ◽  
Clinical Diagnosis ◽  
Focused Ultrasound ◽  
Consensus Statement ◽  
Cerebellar Degeneration ◽  
Considerable Progress ◽  
Clinical Aspects ◽  
Definition Of

ABSTRACTPurpose of the review:To highlight five new things in the research and clinical aspects of essential tremor (ET).Recent findings:The introduction of a new definition of ET and a new category “ET plus” were the major themes of the recent consensus statement. This new change demands a change in the approach to the clinical diagnosis of ET and related diseases. From the pathogenesis standpoint, the cerebellar neurodegenerative model seems to have numerous evidence in its favor compared to the olivary model which has largely fallen out of favor. From the standpoint of therapeutics, magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy has enriched the therapeutic armamentarium.Summary:There has been considerable progress in the field of ET. We discuss five new things in this article which include- (i) new definition (ii) ET plus (iii) approach to the diagnosis of ET, (iv) cerebellar degeneration, and (v) MRgFUS thalamotomy.

Consensus on the change of criteria for cure of acromegaly during the last decade

2011 ◽  
Vol 152 (18) ◽  
pp. 703-708 ◽  
Author(s):  
Gábor László Kovács ◽  
Judit Dénes ◽  
Erika Hubina ◽  
László Kovács ◽  
Sándor Czirják ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Disease Control ◽  
Short Communication ◽  
Consensus Statement ◽  
Diagnosis And Treatment ◽  
Clinical Aspects ◽  
Insulin Like Growth Factor ◽  
Criteria For Diagnosis ◽  
Definition Of

The Acromegaly Consensus Group redefined the consensus criteria for cure of acromegaly. 74 neurosurgeons and experienced endocrinologists summarized the latest results on diagnosis and treatment of acromegaly. In this consensus statement the reliable growth hormone and insulin-like growth factor-1 assays were established. Definition of disease control was discussed based on the available publications and evidence. This short communication summarizes the clinical aspects of consensus criteria for diagnosis and cure of acromegaly based on the original article. Orv. Hetil., 2011, 152, 703–708.

3T magnetic resonance-guided focused ultrasound thalamotomy in patients with essential tremor: Three-year clinical experience from a single center

2021 ◽  
Vol 429 ◽  
pp. 117674
Author(s):  
Stefano Tamburin ◽  
Giuseppe Kenneth Ricciardi ◽  
Tommaso Bovi ◽  
Michele Longhi ◽  
Giorgia Bulgarelli ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Essential Tremor ◽  
Clinical Experience ◽  
Focused Ultrasound ◽  
Single Center

Cost‐Effectiveness of Magnetic Resonance‐Guided Focused Ultrasound for Essential Tremor

2018 ◽  
Vol 34 (5) ◽  
pp. 735-743 ◽  
Author(s):  
Chunmei Li ◽  
Olga Gajic‐Veljanoski ◽  
Alexis K. Schaink ◽  
Caroline Higgins ◽  
Alfonso Fasano ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Magnetic Resonance ◽  
Essential Tremor ◽  
Focused Ultrasound

Unilateral magnetic resonance guided focused ultrasound thalamotomy for essential tremor: practices and clinicoradiological outcomes

2014 ◽  
Vol 86 (3) ◽  
pp. 257-264 ◽  
Author(s):  
W. S. Chang ◽  
H. H. Jung ◽  
E. J. Kweon ◽  
E. Zadicario ◽  
I. Rachmilevitch ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Essential Tremor ◽  
Focused Ultrasound

Cognitive safety after unilateral magnetic resonance-guided focused ultrasound thalamotomy for essential tremor

2019 ◽  
Vol 90 (7) ◽  
pp. 830-831 ◽  
Author(s):  
Carmen Gasca-Salas ◽  
Pasqualina Guida ◽  
Rosanna Piredda ◽  
Ignacio Obeso ◽  
Lydia Vela Desojo ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Essential Tremor ◽  
Focused Ultrasound

scholarly journals What factors impact the clinical outcome of magnetic resonance imaging–guided focused ultrasound thalamotomy for essential tremor?

2020 ◽  
pp. 1-6 ◽  
Author(s):  
Kenji Fukutome ◽  
Yoshihiro Kuga ◽  
Hideyuki Ohnishi ◽  
Hidehiro Hirabayashi ◽  
Hiroyuki Nakase
Keyword(s):  
Magnetic Resonance Imaging ◽  
Treatment Outcome ◽  
Magnetic Resonance ◽  
Essential Tremor ◽  
Focused Ultrasound ◽  
Maximum Temperature ◽  
Resonance Imaging ◽  
Improvement Rate ◽  
Lower Baseline ◽  
Younger Age

OBJECTIVEMagnetic resonance imaging–guided focused ultrasound (MRgFUS) is a novel and useful treatment for essential tremor (ET); however, the factors impacting treatment outcome are unknown. The authors conducted this study to determine the factors affecting the outcome of MRgFUS.METHODSFrom May 2016 through August 2017, 15 patients with ET were admitted to Ohnishi Neurological Center and treated with MRgFUS. To determine the factors impacting treatment outcome, the authors retrospectively studied correlations between the Clinical Rating Scale for Tremor (CRST) improvement rate and age, disease duration, baseline CRST score, skull density ratio (SDR), skull volume, maximum delivered energy, or maximum temperature.RESULTSThe mean CRST score was 18.5 ± 5.8 at baseline and 4.6 ± 5.7 at 1 year. The rate of improvement in the CRST score was 80% ± 22%. Younger age and lower baseline CRST score were correlated with a higher CRST improvement rate (p = 0.025 and 0.007, respectively). To obtain a CRST improvement rate ≥ 50%, a maximum temperature ≥ 55°C was necessary. There was no correlation between SDR and CRST improvement rate (p = 0.658). A lower SDR and higher skull volume required significantly higher maximum delivered energy (p = 0.014 and 0.016, respectively). A higher maximum temperature was associated with a significantly larger lesion volume (p = 0.026).CONCLUSIONSYounger age and lower baseline CRST score were favorable outcome factors. It is important to assess predictive factors when applying MRgFUS.

Magnetic resonance-guided focused ultrasound thalamotomy for treatment of essential tremor: A 2-year outcome study

2018 ◽  
Vol 33 (10) ◽  
pp. 1647-1650 ◽  
Author(s):  
Ying Meng ◽  
Benjamin Solomon ◽  
Alexandre Boutet ◽  
Maheleth Llinas ◽  
Nadia Scantlebury ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Essential Tremor ◽  
Focused Ultrasound ◽  
Outcome Study
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