Spinal Glioblastomas: Report of Seven Cases and Review of the Literature

Neurosurgery ◽  
1991 ◽  
Vol 28 (2) ◽  
pp. 302-306 ◽  
Author(s):  
Pasquale Ciappetta ◽  
Maurizio Salvati ◽  
Giovanna Capoccia ◽  
Marco Artico ◽  
Antonino Raco ◽  
...  
Keyword(s):  
Relevant Literature ◽  
Clinical History ◽  
Pathological Features ◽  
Review Of The Literature ◽  
Slight Tendency ◽  
Salient Features

Abstract Intramedullary glioblastomas are uncommon tumors. They occur chiefly in the cervicothoracic segments, have a slight tendency to occur in the early decades of life, and have a short clinical history before diagnosis. We report seven cases and discuss the salient features of these tumors, particularly the pathological features and treatment, in light of the relevant literature.

scholarly journals Small Cell Ovarian Cancer in Adolescents: Report of Two Cases and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
M. Rovithi ◽  
A. G. Pallis ◽  
A. Kalykaki ◽  
E. Lagoudaki ◽  
L. Giannikaki ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Combination Chemotherapy ◽  
Poor Prognosis ◽  
Relevant Literature ◽  
Malignant Neoplasm ◽  
Standard Of Care ◽  
Small Cell ◽  
Review Of The Literature

Ovarian small cell carcinoma is a rare and highly malignant neoplasm carrying a poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, no regimen can be recommended as standard of care although in the majority of cases platinum-based regimens are used. Herein, we report two cases of small cell carcinoma of the ovaries along with a review of the relevant literature.

scholarly journals Bilateral Renal Tumors in Children: The First 5 Years’ Experience of National Centralization in The Netherlands and a Narrative Review of the Literature

2021 ◽  
Vol 10 (23) ◽  
pp. 5558
Author(s):  
Sophie E. van Peer ◽  
Janna A. Hol ◽  
Alida F. W. van der Steeg ◽  
Martine van Grotel ◽  
Godelieve A. M. Tytgat ◽  
...  
Keyword(s):  
Renal Tumor ◽  
Relevant Literature ◽  
Renal Tumors ◽  
Chemotherapy Response ◽  
Review Of The Literature ◽  
Kidney Tumors ◽  
Tumor Patients ◽  
Nephron Sparing ◽  
Expert Center ◽  
National Expert

Survival of unilateral Wilms tumors (WTs) is exceeding 90%, whereas bilateral WTs have an inferior outcome. We evaluated all Dutch patients with bilateral kidney tumors, treated in the first five years of national centralization and reviewed relevant literature. We identified 24 patients in our center (2015–2020), 23 patients had WT/nephroblastomatosis and one renal cell carcinoma. Patients were treated according to SIOP-RTSG protocols. Chemotherapy response was observed in 26/34 WTs. Nephroblastomatosis lesions were stable (n = 7) or showed response (n = 18). Nephron-sparing surgery was performed in 11/22 patients undergoing surgery (n = 2 kidneys positive margins). Local stage in 20 patients with ≥1 WT revealed stage I (n = 7), II (n = 4) and III (n = 9). Histology was intermediate risk in 15 patients and high risk in 5. Three patients developed a WT in a treated nephroblastomatosis lesion. Two of 24 patients died following toxicity and renal failure, i.e., respectively dialysis-related invasive fungal infection and septic shock. Genetic predisposition was confirmed in 18/24 patients. Our literature review revealed that knowledge is scarce on bilateral renal tumor patients with metastases and that radiotherapy seems important for local stage III patients. Bilateral renal tumors are a therapeutic challenge. We describe management and outcome in a national expert center and summarized available literature, serving as baseline for further improvement of care.

Occupational Therapy Core Skills in Mental Handicap: A Review of the Literature

1992 ◽  
Vol 55 (11) ◽  
pp. 424-428 ◽  
Author(s):  
Linda B M Renton
Keyword(s):  
Occupational Therapy ◽  
Relevant Literature ◽  
Review Of The Literature ◽  
Skill Mix ◽  
Mental Handicap ◽  
The Core ◽  
Core Skills

This article attempts to explore the core skills in occupational therapy by reviewing the relevant literature and then to relate the findings to the field of mental handicap. It should be read in conjunction with recently published and accepted work on occupational therapy core skills and skill mix. A brief overview of the rote of occupational therapy in mental handicap is given and the concept of core skills is defined and discussed with reference to competence, skill mix and teamwork.

SIDS and Sleeping Position

PEDIATRICS ◽  
1993 ◽  
Vol 91 (2) ◽  
pp. 511-512
Author(s):  
DANIEL C. SHANNON ◽  
CARL E. HUNT
Keyword(s):  
Clinical History ◽  
Scientific Data ◽  
Statistical Association ◽  
Review Of The Literature ◽  
Sleeping Position ◽  
Death Scene ◽  
Death Scene Investigation ◽  
Prone Sleeping ◽  
Scene Investigation ◽  
Definition Of

In Reply.— Guntheroth and Spiers,1 displeased with our commentary in Pediatrics,2 have raised many issues. However, the key question is whether the scientific data incriminating the prone position as a contributor to SIDS warrant a recommendation to change sleeping position at this time. Based on our critical review of the literature, we conclude that this recommendation was premature and unwarranted. Accepting the current definition of SIDS as the sudden death of an infant that remains unexplained even after a thorough postmortem examination, death scene investigation, and review of the clinical history, one can decide which of the 15 published studies in which a statistical association is described between prone sleeping and SIDS is acceptable.

Immunoglobulin replacement for primary immunodeficiency: Indications for initiating and continuing treatment

2021 ◽  
Vol 42 (6) ◽  
pp. 489-494 ◽  
Author(s):  
Richard L. Wasserman
Keyword(s):  
Replacement Therapy ◽  
Primary Immunodeficiency ◽  
New Products ◽  
Relevant Literature ◽  
Clinical History ◽  
Laboratory Evaluation ◽  
Burden Of Care ◽  
Continue Treatment ◽  
Immunoglobulin Replacement Therapy ◽  
Immunoglobulin Replacement

Background: Immunoglobulin replacement therapy (IGRT) is the foundation of treatment for the majority of patients with primary immunodeficiency. Clinical history and laboratory evaluation define the patients for whom IGRT is necessary and appropriate. During the 70 years since the first patient was treated, new products have led to the development of several modes of administration that facilitate the individualization of treatment that enables the optimization of care. Objective: The objective was to explain the assessment of candidates for IGRT and approaches to reevaluating recipients of IGRT to decide on the need to continue treatment and to review the approaches to optimize IGRT. Methods: The relevant literature was reviewed in the context of the author's experience supervising > 20,000 IGRT treatments over a 40-year period. Results: Providing the most appropriate form of IGRT for individual patients ameliorates disease and lessens the burden of care for patients with primary immunodeficiency. Conclusion: IGRT is safe and effective when used to treat patients with primary immunodeficiency who meet established and appropriate clinical and laboratory criteria.

scholarly journals Late Recurrence in Ovarian Dysgerminoma Presenting as a Primary Retroperitoneal Tumor: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Yuichiro Sato ◽  
Tohru Hayashi ◽  
Hidetaka Yamamoto ◽  
Ichiro Niina ◽  
Naoya Kuroki ◽  
...  
Keyword(s):  
Clinical History ◽  
Late Recurrence ◽  
Retroperitoneal Tumor ◽  
Retroperitoneal Mass ◽  
Review Of The Literature ◽  
Rare Type ◽  
History Of ◽  
Node Metastases ◽  
Ovarian Dysgerminoma ◽  
Primary Retroperitoneal

Ovarian dysgerminoma is a rare type of germ cell tumor. The majority of patient relapses occur within 2 years of diagnosis. Here, we report the case of a 74-year-old woman with a history of ovarian dysgerminoma 39 years earlier. The patient visited the hospital presenting with heartburn. An abdominal computed tomography (CT) revealed a right retroperitoneal mass, and a primary retroperitoneal tumor was suspected. She underwent surgical resection of the retroperitoneal tumor. Histological examination confirmed a metastatic dysgerminoma to the retroperitoneum. Postoperative CT showed paraaortic and cervical lymph node metastases. The patient was treated with bleomycin, etoposide, and cisplatin chemotherapy. This case demonstrates the difficulties that may be encountered in the differential diagnosis of a retroperitoneal mass and underlines the necessity for understanding a patient’s clinical history.

scholarly journals Juvenile Hemochromatosis: A Case Report and Review of the Literature

2020 ◽  
Vol 13 (8) ◽  
pp. 195
Author(s):  
Akiyoshi Takami ◽  
Yasuaki Tatsumi ◽  
Katsuhisa Sakai ◽  
Yasumichi Toki ◽  
Katsuya Ikuta ◽  
...  
Keyword(s):  
Autosomal Recessive ◽  
Age Of Onset ◽  
Relevant Literature ◽  
Autosomal Recessive Disorder ◽  
Age Difference ◽  
Outpatient Basis ◽  
Review Of The Literature ◽  
Hepcidin Expression ◽  
Juvenile Hemochromatosis ◽  
First Time

Juvenile hemochromatosis (JH), type 2A hemochromatosis, is a rare autosomal recessive disorder of systemic iron overload due to homozygous mutations of HJV (HFE2), which encodes hemojuvelin, an essential regulator of the hepcidin expression, causing liver fibrosis, diabetes, and heart failure before 30 years of age, often with fatal outcomes. We report two Japanese sisters of 37 and 52 years of age, with JH, who showed the same homozygous HJV I281T mutation and hepcidin deficiency and who both responded well to phlebotomy on an outpatient basis. When all reported cases of JH with homozygous HJV mutations in the relevant literature were reviewed, we found—for the first time—that JH developed in females and males at a ratio of 3:2, with no age difference in the two groups. Furthermore, we found that the age of onset of JH may depend on the types of HJV mutations. In comparison to patients with the most common G320V/G320V mutation, JH developed earlier in patients with L101P/L101P or R385X/R385X mutations and later in patients with I281T/I281T mutations.

scholarly journals Penile and intramuscular metastases from esophageal squamous cell carcinoma: A rare case report and review of the literature

2014 ◽  
Vol 8 (11-12) ◽  
pp. 875 ◽  
Author(s):  
Ci Zou ◽  
Yu Dexin ◽  
Wang Qi ◽  
Zhang Tao ◽  
Xie Dongdong ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Relevant Literature ◽  
Review Of The Literature ◽  
Rare Case Report ◽  
Total Esophagectomy ◽  
Intramuscular Metastasis

We present a case with penile and intramuscular metastases of esophageal squamous cell carcinoma. A 61-year-old male had undergone a total esophagectomy and later developed metastatic nodules of the penis and intramuscular metastasis of the thigh. We believe this is the first report of this rare case. We describe the clinical manifestation and offer therapeutic regimen; we also summarize the relevant literature.

scholarly journals Nasopharyngeal Pleomorphic Adenoma: A Rare Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Serdal Celik ◽  
Osman Kilic ◽  
Tulay Zenginkinet ◽  
M. Tayyar Kalcioglu
Keyword(s):  
Salivary Gland ◽  
Case Report ◽  
Pleomorphic Adenoma ◽  
Relevant Literature ◽  
Minor Salivary Gland ◽  
Minor Salivary Glands ◽  
Review Of The Literature ◽  
Neck Tumors ◽  
Rare Case Report ◽  
Chondroid Metaplasia

Salivary gland tumors are rare among all head and neck tumors. Pleomorphic adenoma (PA) is the most commonly seen subtype, and 85% of the cases are located in the parotid gland. PA may very rarely be seen in minor salivary glands. Minor salivary gland PAs are mostly located in the hard and soft palates. Nasopharyngeal PA is very rare, and a total of 8 cases have been published to date. In this case report, a 51-year-old female patient who had nasopharyngeal PA with chondroid metaplasia is presented, and we review the relevant literature.

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