The Responses of Nephtys (Polychaeta: Annelida) to Changes in Hydrostatic Pressure

1969 ◽  
Vol 50 (2) ◽  
pp. 501-513
Author(s):  
ELFED MORGAN

1. An increase in pressure elicited swimming in Nephtys, the number of worms induced to swim being related to the amplitude of the pressure change within the range of stimuli investigated. A decrease in pressure inhibited swimming. 2. The latency of the response to both an increase and a decrease also appears to be related to the magnitude of the stimulus, the worms responding more rapidly to the bigger pressure changes. 3. Brief pulses of pressure lasting 1 sec. elicited neither increase nor decrease in the level of swimming, but pulses of 5 sec. duration induced some individuals to swim. Releasing the pressure at the end of the 5 sec. period resulted in a decrease in the swimming activity below the pre-stimulus level. It is suggested that the different responses may be mediated via separate receptor mechanisms. 4. Phase-angle analysis of the responses to cyclical changes in pressure suggested that the worms were responding primarily to the rate of change of pressure, but the response did not appear to be a simple sine-function of the stimulus. The worms also seemed to be responding in part to some component occurring at twice the basic cycle.

1969 ◽  
Vol 51 (1) ◽  
pp. 203-220
Author(s):  
G. M. HUGHES ◽  
B. KNIGHTS ◽  
C. A. SCAMMELL

1. A technique is described for replacing part of the branchiostegite of Carcinus maenas by a transparent plastic ‘window’ for direct observation of the gills in situ with minimum disturbance. 2. Observation of dye streams shows that most water enters the hypobranchial space through the Milne-Edwards openings above the chelae, flowing anteriorly and/or posteriorly to ventilate most of gills 3-8. Water also enters above the pereiopods to ventilate the rest of the gills. Water passes from the hypobranchial to the epibranchial space, confirming that there is a counterflow with respect to the circulation of blood through the gill lamellae. 3. By sampling water at different points in the branchial system, patterns of oxygen removal were studied. The gradients confirmed the direction of water flow observed by the use of dyes. 4. Rhythmic changes in hydrostatic pressure in normal forward-pumping of 3-12 mm. H2O were recorded from the branchial cavities, superimposed on a maintained negative pressure relative to that outside the crab of 0-10 mm. H2O. Reversals produced a brief positive pressure change of 0-22 mm. H2O. 5. The possible relationships of the rhythmic pressure changes to scaphognathite movements are discussed. 6. The role of reversals is discussed and it is concluded that their primary function during ventilation is in helping to clean the ventrally facing gill surfaces. But they are also important in respiration under certain special conditions which arise during the normal life of the animal. 7. The utilization of O2 during its passage over the gills is low (7-23%) in spite of the counterflow. Possible explanations of this are discussed in relation to a model of the whole ventilation system.


1986 ◽  
Vol 29 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Janet E. Shanks ◽  
Richard H. Wilson

The effects of the direction (ascending and descending) and rate (12.5, 25.0, and 50.0 daPa/s) of ear-canal pressure changes on three tympanometric measures (peak static admittance, shape, and typanometric peak pressure) were studied in 24 adults with normal middle-ear transmission systems. Susceptance, conductance, admittance, and phase angle data for the six conditions both at 226 and 678 Hz were obtained using a general purpose computer. Peak static admittance was significantly affected by both the rate and direction of pressure change as evidenced by a decrease in phase angle for ascending and for fast rates of ear-canal pressure change. Tympanometric shape was broader for descending pressure changes with less frequent notching both for descending and for slow rates of pressure change. Finally, the difference in peak pressure for the two directions of pressure change increased with the rate of ear-canal pressure change.


1964 ◽  
Vol 31 (3) ◽  
pp. 303-313 ◽  
Author(s):  
C. C. Thiel ◽  
P. A. Clough ◽  
D. N. Akam

SummaryA method is described of measuring pressures in a teatcup assembly using strain gauge transducers and simultaneously following movement of the liner wall by means of a cine camera. In preliminary experiments with a narrow bore type liner it was found that pressures below the teat could vary during a single pulsation cycle from a few inches of mercury below atmospheric pressure (inHg vacuum) to as high as 25 inHg vacuum in the absence of an airbleed. Bleeding air into the barrel of the liner or into the clawpiece considerably reduced fluctuation in pressure, and the vacuum barely rose above the nominal milking vacuum of 15 inHg. Reducing the rate of change of pressure in the pulsation chamber did not greatly affect the maximum vacuum obtained. Opening and closing of the liner by pressure change in the pulsation chamber was under some conditions considerably delayed by the pressure conditions existing inside the liner.It is suggested that inertia effects of milk in the cluster and the natural frequency of the system are largely responsible for the observed pressure changes under the teat.


2000 ◽  
Vol 39 (02) ◽  
pp. 200-203
Author(s):  
H. Mizuta ◽  
K. Yana

Abstract:This paper proposes a method for decomposing heart rate fluctuations into background, respiratory and blood pressure oriented fluctuations. A signal cancellation scheme using the adaptive RLS algorithm has been introduced for canceling respiration and blood pressure oriented changes in the heart rate fluctuations. The computer simulation confirmed the validity of the proposed method. Then, heart rate fluctuations, instantaneous lung volume and blood pressure changes are simultaneously recorded from eight normal subjects aged 20-24 years. It was shown that after signal decomposition, the power spectrum of the heart rate showed a consistent monotonic 1/fa type pattern. The proposed method enables a clear interpretation of heart rate spectrum removing uncertain large individual variations due to the respiration and blood pressure change.


1988 ◽  
Vol 97 (2) ◽  
pp. 199-206 ◽  
Author(s):  
Yehuda Finkelstein ◽  
Yuval Zohar ◽  
Yoav P. Talmi ◽  
Nelu Laurian

The Toynbee maneuver, swallowing when the nose is obstructed, leads in most cases to pressure changes in one or both middle ears, resulting in a sensation of fullness. Since first described, many varying and contradictory comments have been reported in the literature concerning the type and amount of pressure changes both in the nasopharynx and in the middle ear. In our study, the pressure changes were determined by catheters placed into the nasopharynx and repeated tympanometric measurements. New information concerning the rapid pressure variations in the nasopharynx and middle ear during deglutition with an obstructed nose was obtained. Typical individual nasopharyngeal pressure change patterns were recorded, ranging from a maximal positive pressure of + 450 to a negative pressure as low as −320 mm H2O.


1967 ◽  
Vol 46 (2) ◽  
pp. 307-315 ◽  
Author(s):  
E. DON STEVENS ◽  
D. J. RANDALL

1. Changes in blood pressure in the dorsal aorta, ventral aorta and subintestinal vein, as well as changes in heart rate and breathing rate during moderate swimming activity in the rainbow trout are reported. 2. Blood pressures both afferent and efferent to the gills increased during swimming and then returned to normal levels within 30 min. after exercise. 3. Venous blood pressure was characterized by periodic increases during swimming. The pressure changes were not in phase with the body movements. 4. Although total venous return to the heart increased during swimming, a decreased blood flow was recorded in the subintestinal vein. 5. Heart rate and breathing rate increased during swimming and then decreased when swimming ceased. 6. Some possible mechanisms regulating heart and breathing rates are discussed.


Author(s):  
Saber Rezaey

One of the most important components of fluid transmission systems is a control valve located in the pipelines of oil, gas, etc. The primary purpose of this valve is to control the rate of fluid flow passing through it under pressure changes and the most important issue is to investigate the flow’s characteristics in order to achieve a proper geometry to control the flow rate and pressure as desired. The valves used in pipelines add to the overall head loss of the system. Therefore, valves with proper geometry can reduce these minor losses and finally decrease total energy losses. In this paper, a globe control valve is modeled and then numerically investigated to extract its functional relation, which relates pressure ratio to inlet Reynolds number, and estimate its loss coefficient at the valve’s different opening states which have not been addressed completely before and can be beneficial for the selection and usage of globe valves under certain conditions. According to the results, it is found that pressure ratio and loss coefficient are functions of inlet velocity and the valve’s opening state’s percentage, which are directly related to the valve’s geometry. When the valve opens, the rate of change in pressure ratio and loss coefficient are very sharp. Gradually, this rate decreases and the results tend to the final value at the valve’s fully opened state.


Heart ◽  
2021 ◽  
pp. heartjnl-2021-319110
Author(s):  
Dae Hyun Lee ◽  
Fahad Hawk ◽  
Kieun Seok ◽  
Matthew Gliksman ◽  
Josephine Emole ◽  
...  

BackgroundIbrutinib is a tyrosine kinase inhibitor most commonly associated with atrial fibrillation. However, additional cardiotoxicities have been identified, including accelerated hypertension. The incidence and risk factors of new or worsening hypertension following ibrutinib treatment are not as well known.MethodsWe conducted a retrospective study of 144 patients diagnosed with B cell malignancies treated with ibrutinib (n=93) versus conventional chemoimmunotherapy (n=51) and evaluated their effects on blood pressure at 1, 2, 3 and 6 months after treatment initiation. Descriptive statistics were used to compare baseline characteristics for each treatment group. Fisher’s exact test was used to identify covariates significantly associated with the development of hypertension. Repeated measures analyses were conducted to analyse longitudinal blood pressure changes.ResultsBoth treatments had similar prevalence of baseline hypertension at 63.4% and 66.7%, respectively. There were no differences between treatments by age, sex and baseline cardiac comorbidities. Both systolic and diastolic blood pressure significantly increased over time with ibrutinib compared with baseline, whereas conventional chemoimmunotherapy was not associated with significant changes in blood pressure. Baseline hypertensive status did not affect the degree of blood pressure change over time. A significant increase in systolic blood pressure (defined as more than 10 mm Hg) was noted for ibrutinib (36.6%) compared with conventional chemoimmunotherapy (7.9%) at 1 month after treatment initiation. Despite being hypertensive at follow-up, 61.2% of patients who were treated with ibrutinib did not receive adequate blood pressure management (increase or addition of blood pressure medications). Within the ibrutinib group, of patients who developed more than 20 mm Hg increase in systolic blood pressure, only 52.9% had hypertension management changes.ConclusionsIbrutinib is associated with the development of hypertension and worsening of blood pressure. Cardiologists and oncologists must be aware of this cardiotoxicity to allow timely management of blood pressure elevations.


1966 ◽  
Vol 45 (2) ◽  
pp. 197-202
Author(s):  
R. A. HAMMOND

1. Two indirect methods for recording changes of hydrostatic pressure within the trunk of Acanthocephalus ranae have been described. 2. Internal pressure has been shown to be lowest when the trunk is fully contracted and the proboscis invaginated, and highest when the trunk is fully elongated. 3. A rapid rise of internal pressure occurs when the circular trunk muscles contract. 4. Overall internal pressure changes of up to 0.5 cm. Hg have been shown to occur in active specimens. 5. The body length when fully extended is only 40-50% greater than when contracted. 6. The correlation between muscular activity, body shape, and internal hydrostatic pressure in A. ranae is discussed


2021 ◽  
Author(s):  
Sebastian Müller ◽  
Andreas Malcherek

Abstract In this paper a unified approach based on the momentum balance is presented, capable of predicting the pressure change of sudden contractions and sudden expansions. The use of empirically determined correction coefficients is not necessary. Therefore, the momentum balance is derived similarly for both applications but with different control volumes. The control volume takes into account the specific geometry of the hydraulic structure. With a properly chosen control volume, the unified approach requires coefficients that account for the velocity as well as pressure distributions on the boundaries of the control volume. These coefficients can be obtained by parameterizing the results of numerical simulations by simple analytical functions. The numerical model itself is validated by checking the simulated pressure change against calculated or measured pressure changes. It is found that the formulation of the momentum balance for the sudden expansion is more complex compared with the sudden contraction. The prediction of the pressure change of flows through sudden expansions can be improved by applying the momentum balance non-idealized. Most of the correction coefficients originate from an inappropriate application of Bernoulli’s energy conservation principle. Consequently, this leads to a gap between theory and experimental results. The proposed unified approach solely contains physical coefficients that are used to substitute integrals by averaged expressions.


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