scholarly journals Syntheses of Ion-exchange Resins. I. Syntheses of Ion-exchange Resins of Carboxylic Acid Type.

1954 ◽  
Vol 57 (7) ◽  
pp. 506-507
Author(s):  
Hiroshi Suda ◽  
Ryohei Oda
1957 ◽  
Vol 10 (4) ◽  
pp. 484 ◽  
Author(s):  
MP Hegarty

The isolation and identification of 5-hydroxypiperidine-2-carboxylic acid from the leaves of L. glauca Benth. by procedures using ion-exchange resins and chromatography are described. This imino acid has been synthesized and the resulting diastereo-isomers separated by chromatographic techniques. The stereochemistry of the natural and the synthetic compounds is discussed.


1960 ◽  
Vol 38 (12) ◽  
pp. 2285-2289 ◽  
Author(s):  
J. K. N. Jones ◽  
R. A. Wall ◽  
A. O. Pittet

Fractionation according to molecular size has been achieved by development of oligosaccharide mixtures with water on columns of neutral salt forms of sulphonic acid type ion-exchange resins. The method was used to separate a synthetic mixture of raffinose, sucrose, and glucose and a number of hydrolyzates of polysaccharides to give clean, salt-free fractions of high purity. The procedure is rapid and economical and provides a useful extension of older methods of separating such mixtures.


1960 ◽  
Vol 38 (12) ◽  
pp. 2290-2294 ◽  
Author(s):  
J. K. N. Jones ◽  
R. A. Wall

Columns of neutral salt forms of sulphonic acid type ion-exchange resins have been shown to be useful in separations of monosaccharide mixtures with water as the developing solvent. A number of synthetic mixtures and a series of plant extracts have been resolved into clean, salt-free fractions by use of the new technique. The procedure is analogous to column partition chromatography, but in many cases it is more rapid and gives a useful extension of separability.


1970 ◽  
Vol 25 (8) ◽  
pp. 808-820 ◽  
Author(s):  
K. Bunzl ◽  
B. Sansoni

The hydration of carboxylic acid groups in ion exchange resins was studied by means of dielectric measurements. For three resins carrying carboxylic groups with quite different pK-values the dielectric constant and the dielectric loss were measured as a function of frequency, water content, and temperature. A comparison of their behaviour showed that the observed dielectric dispersion is due to a Maxwell-Wagner mechanism. In the course of the water adsorption the resin with very weak carboxylic acid groups exhibited a discontinuity of the dielectric constant, if one molecule of water was attached to two carboxylic groups. This can be explained by assuming that the carboxylic groups which are connected by hydrogen bonds in the dry state begin to dissociate at the above mentioned water content. As a consequence, the formation of H5O2⊕-complexes becomes possible. The corresponding increase of the proton mobility leads to the observed Maxwell-Wagner effects. Hydration structures of the carboxylic acid groups below and above this critical water content are proposed.In the case of the two other resins with higher acidity of the carboxyl groups no discontinuity during water sorption could be observed. The mobility of the proton and hence the Maxwell-Wagner effects could thus be observed at much lower water contents.The appreciable differences in the shapes of the corresponding wateradsorption isotherms are in agreement with conclusions from the dielectric measurements.


1969 ◽  
Vol 22 (2) ◽  
pp. 449 ◽  
Author(s):  
EOP Thompson R Hosken ◽  
GM Air

A haemolysate of red blood cells of the grey kangaroo, M. giganteu8, gave several haemoglobin peaks when chromatographed on polycarboxylic-acid-type ion-exchange resins. In the four samples studied two major components, haemoglobin I and II, were present. In the sample examined in detail these comprised 51 and 45% respectively, together with about 4% of minor haem-containing proteins. The two major haemoglobin components were readily separated by chromatography at pH 6�4 in phosphate buffer of 0 �152M sodium-potassium ion concentration.


Author(s):  
Ann M. Thomas ◽  
Virginia Shemeley

Those samples which swell rapidly when exposed to water are, at best, difficult to section for transmission electron microscopy. Some materials literally burst out of the embedding block with the first pass by the knife, and even the most rapid cutting cycle produces sections of limited value. Many ion exchange resins swell in water; some undergo irreversible structural changes when dried. We developed our embedding procedure to handle this type of sample, but it should be applicable to many materials that present similar sectioning difficulties.The purpose of our embedding procedure is to build up a cross-linking network throughout the sample, while it is in a water swollen state. Our procedure was suggested to us by the work of Rosenberg, where he mentioned the formation of a tridimensional structure by the polymerization of the GMA biproduct, triglycol dimethacrylate.


Author(s):  
Kathpalia Harsha ◽  
Das Sukanya

Ion Exchange Resins (IER) are insoluble polymers having styrene divinylbenzene copolymer backbone that contain acidic or basic functional groups and have the ability to exchange counter ions with the surrounding aqueous solutions. From the past many years they have been widely used for purification and softening of water and in chromatographic columns, however recently their use in pharmaceutical industry has gained considerable importance. Due to the physical stability and inert nature of the resins, they can be used as a versatile vehicle to design several modified release dosage forms The ionizable drug is complexed with the resin owing to the property of ion exchange. This resin complex dissociatesin vivo to release the drug. Based on the dissociation strength of the drug from the drug resin complex, various release patterns can be achieved. Many formulation glitches can be circumvented using ion exchange resins such as bitter taste and deliquescence. These resins also aid in enhancing disintegrationand stability of formulation. This review focuses on different types of ion exchange resins, their preparation methods, chemistry, properties, incompatibilities and their application in various oral drug delivery systems as well as highlighting their use as therapeutic agents.


2004 ◽  
Vol 3 (3) ◽  
pp. 447-455
Author(s):  
Viky Dicu ◽  
Carmen Iesan ◽  
Mihai Chirica ◽  
Satish Bapat

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