scholarly journals Androgen Modulators from the Roots of Paeonia lactiflora (Paeoniae Radix) Grown and Processed in Nara Prefecture, Japan

2009 ◽  
Vol 57 (9) ◽  
pp. 971-974 ◽  
Author(s):  
Kazuto Washida ◽  
Yoshiyuki Itoh ◽  
Takashi Iwashita ◽  
Kyosuke Nomoto
Keyword(s):  
Paeonia Lactiflora ◽  
Paeoniae Radix ◽  
Nara Prefecture

scholarly journals Single Standard Substance for the Simultaneous Determination of Eleven Components in the Extract of Paeoniae Radix Alba (Root of Paeonia lactiflora Pall.)

2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Menglan Shen ◽  
Qiaoyan Zhang ◽  
Luping Qin ◽  
Binjun Yan
Keyword(s):  
Simultaneous Determination ◽  
High Performance ◽  
Low Cost ◽  
Extraction Process ◽  
Chemical Components ◽  
Paeonia Lactiflora ◽  
External Standard Method ◽  
Single Standard ◽  
Paeoniae Radix

Paeoniae Radix Alba (PRA), an herbal drug produced from the root of Paeonia lactiflora Pall., is widely used in many herbal medicine prescriptions/preparations. Since the pharmacological effects of PRA come from multiple chemical components, it is important to establish a method for the determination of those components in PRA extracts with simple operation and low cost, which is more suitable to evaluate the quality of PRA extracts and optimize the extraction process. This work introduced the quantitative analysis of multicomponents with a single-marker (QAMS) method for the simultaneous determination of eleven bioactive components in PRA extracts, including gallic acid, oxypaeoniflorin, catechin, albiflorin, paeoniflorin, ethyl gallate, galloylpaeoniflorin, pentagalloylglucose, benzoic acid, benzoylpaeoniflorin, and paeonol. In the QAMS method established based on high performance liquid chromatography with diode array detection, only the reference substance of paeoniflorin was needed, and the other ten components were determined based on their relative correction factors (RCFs) to paeoniflorin. Moreover, the repeatability and robustness of the RCFs were studied with different column temperatures, detection wavelengths, flow rates, column types, and instruments. In method validation, good linearity (r > 0.999), stability, repeatability (RSD < 1.9%), and accuracy (recoveries within 96.1%–105.5%) were shown. Sample analyses showed that the QAMS method was consistent with the conventional external standard method. The established method provided a comprehensive, efficient, and low-cost tool for the routine quality evaluation of PRA extracts.

scholarly journals Carbon Dots from Paeoniae Radix Alba Carbonisata: Hepatoprotective Effect

2020 ◽  
Vol Volume 15 ◽  
pp. 9049-9059
Author(s):  
Yusheng Zhao ◽  
Yue Zhang ◽  
Hui Kong ◽  
Meiling Zhang ◽  
Jinjun Cheng ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Hepatoprotective Effect ◽  
Paeoniae Radix

scholarly journals Relationship between initial peritoneal dialysis modality and risk of peritonitis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maiko Kokubu ◽  
Masaru Matsui ◽  
Takayuki Uemura ◽  
Katsuhiko Morimoto ◽  
Masahiro Eriguchi ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Lower Risk ◽  
Observational Studies ◽  
Primary Outcome ◽  
Propensity Scores ◽  
First Episode ◽  
Connection Type ◽  
Adjusted Model ◽  
The Relationship ◽  
Nara Prefecture

Abstract Peritonitis is a critical complication of peritoneal dialysis (PD). Investigators have reported the risk of peritonitis in patients on continuous ambulatory peritoneal dialysis (CAPD) versus automated peritoneal dialysis (APD), but the available evidence is predominantly based on observational studies which failed to report on the connection type. Our understanding of the relationship between peritonitis risk and PD modality thus remained insufficient. We studied 285 participants who began PD treatment between 1997 and 2014 at three hospitals in Nara Prefecture in Japan. We matched 106 APD patients with 106 CAPD patients based on their propensity scores. The primary outcome was time to first episode of peritonitis within 3 years after PD commencement. In total, PD peritonitis occurred in 64 patients during the study period. Patients initiated on APD had a lower risk of peritonitis than did those initiated on CAPD in both the unadjusted and adjusted models. The hazard ratio (HR) and 95% confidence interval (CI) for the primary endpoint were 0.30 (0.17–0.53) in the fully adjusted model including connection type. In the matched cohort, APD patients had a significantly lower risk of peritonitis than did CAPD patients (log-rank: p < 0.001, HR 0.32, 95% CI 0.16–0.59). The weighting-adjusted analysis of the inverse probability of treatment yielded a similar result (HR 0.35, 95% CI 0.18–0.67). In conclusion, patients initiated on APD at PD commencement had a reduced risk of peritonitis compared with those initiated on CAPD, suggesting APD may be preferable for prevention of peritonitis among PD patients.

scholarly journals The complete chloroplast genome of Paeonia lactiflora Pall. (Paeoniaceae)

2019 ◽  
Vol 4 (2) ◽  
pp. 2715-2716 ◽  
Author(s):  
Minjee Lee ◽  
Jin Hee Park ◽  
Jinsu Gil ◽  
Jungho Lee ◽  
Yi Lee
Keyword(s):  
Chloroplast Genome ◽  
Paeonia Lactiflora ◽  
Complete Chloroplast Genome

ВЛИЯНИЕ РАЗНЫХ СУБСТРАТОВ НА РАЗМНОЖЕНИЕ КОРНЕВЫМИ ЧЕРЕНКАМИ ПИОНА МОЛОЧНОЦВЕТКОВОГО PAEONIA LACTIFLORA PALL.

2021 ◽  
pp. 18-18
Author(s):  
А. А. Жукова ◽  
Н. Г. Коршикова
Keyword(s):  
Paeonia Lactiflora

В статье представлены результаты исследования особенностей размножения пиона корневыми черенками. На первом этапе исследовали способности к размножению корневыми черенками трех сортов: «Sweet Sixteen» (Свит Сикстин), «Maestro» (Маэстро), «Sarah Bernhardt» (Сара Бернар) – для выявления сорта с более высокими показателями укоренения. По результатам выбрали сорт «Sarah Bernhardt» (укоренение черенков 60 %, против 32 и 12 % соответственно). На втором этапе опыта изучили влияние субстрата и диаметра корневого черенка на укоренение, на примере сорта «Sarah Bernhardt» (Сара Бернар). Корневые черенки обработали Фитоспорином М. и регулятором роста Корневин СП. Варианты опыта: контроль – торфогрунт без обработки Фитоспорином М., торфогрунт, вермикулит, сфагнум, перлит. Во всех вариантах, кроме контроля, субстраты обработаны Фитоспорином М. Установлено, что наиболее оптимальный вариант для укоренения – торфогрунт, обработанный Фитоспорином М. В контроле процент укоренения равен 83,4 %, средняя длина образовавшихся корешков от 1,8 до 2,9 см, а среднее число образовавшихся корешков на черенке равно 6,2 шт. В варианте с обработанным торфогрунтом процент укоренения равен 94,5 %, средняя длина образовавшихся корешков от 1,3 до 3,8 см, а среднее число образовавшихся корешков на черенке равен 14,4 шт. Остальные субстраты оказались непригодными для укоренения черенков. На результаты укоренения черенков оказывало влияние диаметр черенка. Черенки диаметром 2,0 см имели меньший процент укоренения по сравнению с черенками диаметром 1,0 и 1,5 см.

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