scholarly journals Evaluation of Mixing Performance of Large Paddle Impeller HRX300

2021 ◽  
Vol 47 (6) ◽  
pp. 257-261
Author(s):  
Ryota Nishida ◽  
Chihiro Koide ◽  
Haruki Furukawa ◽  
Yoshihito Kato ◽  
Yoshikazu Kato ◽  
...  
Keyword(s):  
Processes ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 464
Author(s):  
Xingren Jiang ◽  
Ning Yang ◽  
Rijie Wang

Continuous manufacturing has received increasing interest because of the advantages of intrinsic safety and enhanced mass transfer in the pharmaceutical industry. However, the difficulty for scale-up has limited the application of continuous manufacturing for a long time. Recently, the tubular flow reactor equipped with the Kenics static mixer appears to be a solution for the continuous process scale-up. Although many influence factors on the mixing performance in the Kenics static mixer have been investigated, little research has been carried out on the aspect ratio. In this study, we used the coefficient of variation as the mixing evaluation index to investigate the effect of the aspect ratio (0.2–2) on the Kenics static mixer’s mixing performance. The results indicate that a low aspect ratio helps obtain a shorter mixing time and mixer length. This study suggests that adjusting the aspect ratio of the Kenics static mixer can be a new strategy for the scale-up of a continuous process in the pharmaceutical industry.


2021 ◽  
Vol 13 (8) ◽  
pp. 4255
Author(s):  
Mingmin Kong ◽  
Shuaiming Feng ◽  
Qi Xia ◽  
Chen Chen ◽  
Zhouxin Pan ◽  
...  

Hydrogen is of great significance for replacing fossil fuels and reducing carbon dioxide emissions. The application of hydrogen mixing with natural gas in gas network transportation not only improves the utilization rate of hydrogen energy, but also reduces the cost of large-scale updating household or commercial appliance. This paper investigates the necessity of a gas mixing device for adding hydrogen to existing natural gas pipelines in the industrial gas network. A three-dimensional helical static mixer model is developed to simulate the mixing behavior of the gas mixture. In addition, the model is validated with experimental results. Parametric studies are performed to investigate the effect of mixer on the mixing performance including the coefficient of variation (COV) and pressure loss. The research results show that, based on the, the optimum number of mixing units is three. The arrangement of the torsion angle of the mixing unit has a greater impact on the COV. When the torsion angle θ = 120°, the COV has a minimum value of 0.66%, and when the torsion angle θ = 60°, the COV has a maximum value of 8.54%. The distance of the mixing unit has little effect on the pressure loss of the mixed gas but has a greater impact on the COV. Consecutive arrangement of the mixing units (Case A) is the best solution. Increasing the distance of the mixing unit is not effective for the gas mixing effect. Last but not least, the gas mixer is optimized to improve the mixing performance.


Processes ◽  
2020 ◽  
Vol 8 (10) ◽  
pp. 1236
Author(s):  
Hamid Mortazavi ◽  
Leila Pakzad

Oscillatory baffled reactors (OBRs) have attracted much attention from researchers and industries alike due to their proven advantages in mixing, scale-up, and cost-effectiveness over conventional stirred tank reactors (STRs). This study quantitatively investigated how different mixing indices describe the mixing performance of a moving baffle OBR using computational fluid dynamics (CFD). In addition, the hydrodynamic behavior of the reactor was studied, considering parameters such as the Q-criterion, shear strain rate, and velocity vector. A modification of the Q-criterion showed advantages over the original Q-criterion in determination of the vortices’ locations. The dynamic mesh tool was utilized to simulate the moving baffles through ANSYS/Fluent. The mixing indices studied were the velocity ratio, turbulent length scale, turbulent time scale, mixing time, and axial dispersion coefficient. We found that the oscillation amplitude had the most significant impact on these indices. In contrast, the oscillatory Reynolds number did not necessarily describe the mixing intensity of a system. Of the tested indices, the axial dispersion coefficient showed advantages over the other indices for quantifying the mixing performance of a moving baffle OBR.


Author(s):  
Joseph R. Nalbach ◽  
Dave Jao ◽  
Douglas G. Petro ◽  
Kyle M. Raudenbush ◽  
Shibbir Ahmad ◽  
...  

A common method to precisely control the material properties is to evenly distribute functional nanomaterials within the substrate. For example, it is possible to mix a silk solution and nanomaterials together to form one tuned silk sample. However, the nanomaterials are likely to aggregate in the traditional manual mixing processes. Here we report a pilot study of utilizing specific microfluidic mixing designs to achieve a uniform nanomaterial distribution with minimal aggregation. Mixing patterns are created based on classic designs and then validated by experimental results. The devices are fabricated on polydimethylsiloxane (PDMS) using 3D printed molds and soft lithography for rapid replication. The initial mixing performance is validated through the mixing of two solutions with colored dyes. The microfluidic mixer designs are further analyzed by creating silk-based film samples. The cured film is inspected with scanning electron microscopy (SEM) to reveal the distribution uniformity of the dye particles within the silk material matrix. Our preliminary results show that the microfluidic mixing produces uniform distribution of dye particles. Because the microfluidic device can be used as a continuous mixing tool, we believe it will provide a powerful platform for better preparation of silk materials. By using different types of nanomaterials such as graphite (demonstrated in this study), graphene, carbon nanotubes, and magnetic nanoparticles, the resulting silk samples can be fine-tuned with desired electrical, mechanical, and magnetic properties.


2017 ◽  
Vol 24 (6) ◽  
pp. 2599-2610 ◽  
Author(s):  
Ranjitsinha R. Gidde ◽  
Prashant M. Pawar ◽  
Babruvahan P. Ronge ◽  
Nitin D. Misal ◽  
Ranjit B. Kapurkar ◽  
...  

2012 ◽  
Vol 501 ◽  
pp. 388-392
Author(s):  
Hui Guang Bian ◽  
Wei Shuai Lv ◽  
Chuan Sheng Wang

The paper is used to analyze the structure of traditional synchronous rotor from the perspective which the helix angle between long edge and short edge has some difference. The specialized viscoelastic fluid software--Polyflow is used to dynamic simulation analyze the two different kinds of rotors during the process of flow mixing, and then to analyze the two kinds of rotor performance through the result of transient flow simulation which mixed for one second. The analysis revealed that the improved synchronous rotor had better axial tensile properties in the case of remaining the original performance basically unchanged. And that could improve mixing performance and the production efficiency of mixer more effectively. There will provide a theoretical basis for the optimization of the rotor configuration in future.


1987 ◽  
Vol 53 (491) ◽  
pp. 2037-2040
Author(s):  
Teruyoshi UMEMURA ◽  
Kazuo MINENO ◽  
Fuminori KAMEMIZU ◽  
Yoshihiro SEINO

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