scholarly journals An assessment of the extent to which the contents of PROSPERO records meet the systematic review protocol reporting items in PRISMA-P

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 773
Author(s):  
Alison Booth ◽  
Alex S. Mitchell ◽  
Andrew Mott ◽  
Sophie James ◽  
Sarah Cockayne ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
A Priori ◽  
Health Interventions ◽  
Systematic Review Protocol ◽  
Eligibility Criteria ◽  
Single Entry ◽  
Review Protocol ◽  
The Mean ◽  
Source Of Information

Background: PROSPERO is an international prospective register for systematic review protocols. Many of the registrations are the only available source of information about planned methods. This study investigated the extent to which records in PROSPERO contained the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Methods: A random sample of 439 single entry PROSPERO records of reviews of health interventions registered in 2018 was identified. Using a piloted list of 19 PRISMA-P items, divided into 63 elements, two researchers independently assessed the registration records. Where the information was present or not applicable to the review, a score of 1 was assigned. Overall scores were calculated and comparisons made by stage of review at registration, whether or not a meta-analysis was planned and whether or not funding/sponsorship was reported. Results: Some key methodological details, such as eligibility criteria, were relatively frequently reported, but much of the information recommended in PRISMA-P was not stated in PROSPERO registrations. Considering the 19 items, the mean score was 4.8 (SD 1.8; median 4; range 2-11) and across all the assessed records only 25% (2081/8227) of the items were scored as reported. Considering the 63 elements, the mean score was 33.4 (SD 5.8; median 33; range 18-47) and overall, 53% (14,469/27,279) of the elements were assessed as reported. Reporting was more frequent for items required in PROSPERO than optional items. The planned comparisons showed no meaningful differences between groups. Conclusions: PROSPERO provides reviewers with the opportunity to be transparent in their planned methods and demonstrate efforts to reduce bias. However, where the PROSPERO record is the only available source of a priori reporting, there is a significant shortfall in the items reported, compared to those recommended. This presents challenges in interpretation for those wishing to assess the validity of the final review.

scholarly journals An assessment of the extent to which the contents of PROSPERO records meet the systematic review protocol reporting items in PRISMA-P

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 773
Author(s):  
Alison Booth ◽  
Alex S. Mitchell ◽  
Andrew Mott ◽  
Sophie James ◽  
Sarah Cockayne ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
A Priori ◽  
Health Interventions ◽  
Systematic Review Protocol ◽  
Eligibility Criteria ◽  
Single Entry ◽  
Review Protocol ◽  
The Mean ◽  
Source Of Information

Background: PROSPERO is an international prospective register for systematic review protocols. Many of the registrations are the only available source of information about planned methods. This study investigated the extent to which records in PROSPERO contained the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). Methods: A random sample of 439 single entry PROSPERO records of reviews of health interventions registered in 2018 was identified. Using a piloted list of 19 PRISMA-P items, divided into 63 elements, two researchers independently assessed the registration records. Where the information was present or not applicable to the review, a score of 1 was assigned. Overall scores were calculated and comparisons made by stage of review at registration, whether or not a meta-analysis was planned and whether or not funding/sponsorship was reported. Results: Some key methodological details, such as eligibility criteria, were relatively frequently reported, but much of the information recommended in PRISMA-P was not stated in PROSPERO registrations. Considering the 19 items, the mean score was 4.8 (SD 1.8; median 4; range 2-11) and across all the assessed records only 25% (2081/8227) of the items were scored as reported. Considering the 63 elements, the mean score was 33.4 (SD 5.8; median 33; range 18-47) and overall, 53% (14,469/27,279) of the elements were assessed as reported. Reporting was more frequent for items required in PROSPERO than optional items. The planned comparisons showed no meaningful differences between groups. Conclusions: PROSPERO provides reviewers with the opportunity to be transparent in their planned methods and demonstrate efforts to reduce bias. However, where the PROSPERO record is the only available source of a priori reporting, there is a significant shortfall in the items reported, compared to those recommended. This presents challenges in interpretation for those wishing to assess the validity of the final review.

scholarly journals Pulmonary rehabilitation for COVID-19: A living systematic review protocol

Medwave ◽  
2021 ◽  
Vol 21 (06) ◽  
pp. e8223-e8223
Author(s):  
Stefanie Arce Pardo ◽  
Shuheng Lai ◽  
Luis Ortiz-Muñoz ◽  
Francisca Verdugo-Paiva ◽  
Gabriel Rada
Keyword(s):  
Systematic Review ◽  
Pulmonary Rehabilitation ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Systematic Review Protocol ◽  
Traditional Media ◽  
Eligibility Criteria ◽  
Assessment Development ◽  
Review Protocol

Objective This living systematic review aims to provide a timely, rigorous and continuously updated summary of the evidence available on the role of pulmonary rehabilitation in the treatment of patients with COVID-19. Design This is the protocol of a living systematic review. Data sources We will conduct searches in the L·OVE (Living OVerview of Evidence) platform for COVID-19, a system that maps PICO questions to a repository maintained through regular searches in electronic databases, preprint servers, trial registries and other resources relevant to COVID-19. No date or language restrictions will be applied. Eligibility criteria for selecting studies and methods We adapted an already published common protocol for multiple parallel systematic reviews to the specificities of this question. We will include randomized trials evaluating the effect of pulmonary rehabilitation as monotherapy or in combination with other interventions-versus sham or no treatment in patients with COVID-19. Two reviewers will independently screen each study for eligibility, extract data, and assess the risk of bias. We will pool the results using meta-analysis and will apply the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to assess the certainty of the evidence for each outcome. Ethics and dissemination No ethics approval is considered necessary. The results of this review will be widely disseminated via peer-reviewed publications, social networks and traditional media.

scholarly journals 3D photography versus digital planimetry in wound measurement : a systematic review protocol

2021 ◽  
Author(s):  
Parinaz Onikzeh ◽  
◽  
Afshin Heidari ◽  
Aida Kazemi ◽  
Parisa Najjariasl ◽  
...  
Keyword(s):  
Systematic Review ◽  
Area Measurement ◽  
Wound Management ◽  
Systematic Review Protocol ◽  
Eligibility Criteria ◽  
Wound Area ◽  
Venous Ulcers ◽  
Review Protocol ◽  
Review Question ◽  
3D Photography

Review question / Objective: The aim of this study is to find whether there is concordance between two methods of wound area measurement: 3D photography and digital planimetry. Condition being studied: One of the most important factors in all types of wound management is wound measurement and two new digital techniques are : digital planimetry and 3D-photography. Eligibility criteria: the articles will be included only if the study cases would be measured by both methods of wound measurement including 3D photography and digital planimetry. patients with wound in any area of their body like diabetic ulcers, venous ulcers or burning. not models or animals.not bite or scar or bruising. without any restriction in age or gender.

Effectiveness of Physiotherapy to Promote Motor Recovery in Individuals with Stroke: A Systematic Review Protocol

2022 ◽  
Author(s):  
Shehong Zhang ◽  
Hongyu Xie ◽  
Chuanjie Wang ◽  
Fengfeng Wu ◽  
Xin Wang
Keyword(s):  
Systematic Review ◽  
Motor Function ◽  
Systematic Reviews ◽  
Evaluation System ◽  
Meta Analysis ◽  
Primary Data ◽  
Cochrane Library ◽  
Systematic Review Protocol ◽  
Qualitative Synthesis ◽  
Review Protocol

Abstract Introduction: Motor function is essential in our daily lives, one of the most common impairments caused by stroke is loss of functional movement. Over 70% of stroke survivors have motor or other neurological functional disabilities. However, rehabilitation of motor function suffered from a stroke can be rather difficult due to the complexity of organs and systems related to motor function, as well as the neural system that supported motor function. In particularly, previous evidence for the effectiveness of physiotherapy, a commonly prescribed intervention method for people with stroke, that recover motor function in people following a stroke is varied and limited in the chronic rehabilitation phase and therefore has never been reviewed systematically. With the progress of study in neurology and the development of novel tools for rehabilitation, results from more and more clinical trials are now available, thus here justifying conducting a systematic review. Methods and analysis: This systematic review protocol is developed in accordance with the methodology recommended by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols, as well as the Cochrane handbook for systematic reviews of interventions. Relevant studies will be identified by searching the databases. We will perform searches for relevant studies in databases, including PubMed, Embase, CINAHL, and Web of Science, Physiotherapy Evidence Database and Cochrane Library databases. The reference lists of included articles and reviews will be searched manually. The date range parameters used in searching all databases will be restricted between January 2001 and January 2021. Randomized controlled trials (RCTs) published will be included. The language used in the articles included was restricted to English. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation system from the Cochrane Handbook for Systematic Reviews of Interventions) approach will be used to systematically appraise the quality of methodology. We will assess the risk of bias of the RCTs included using the Cochrane Collaboration’s tool and provide a qualitative synthesis. After that, we will consider conducting a meta-analysis if the final data across outcomes shows sufficient homogeneity. Ethics and dissemination: No ethical approval is needed as the proposed study does not involve the collection of primary data, and the results of this review will be disseminated via peer-reviewed publications and conference presentations. Trial registration number: CRD42021267069.

scholarly journals Diagnostic Value of TLE1 in Synovial Sarcoma: A Systematic Review and Meta-Analysis

Sarcoma ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Marc El Beaino ◽  
Daniel C. Jupiter ◽  
Tarek Assi ◽  
Elie Rassy ◽  
Alexander J. Lazar ◽  
...  
Keyword(s):  
Systematic Review ◽  
Synovial Sarcoma ◽  
Predictive Value ◽  
Meta Analysis ◽  
Diagnostic Value ◽  
Cochrane Library ◽  
Specific Marker ◽  
Eligibility Criteria ◽  
Depth Analysis ◽  
The Mean

Background. Synovial sarcoma can present morphologically in multiple forms, including biphasic and monophasic subtypes. As a result, the histological diagnosis can sometimes be challenging. Transducin-Like Enhancer 1 (TLE1) is a transcriptional corepressor that normally is involved in embryogenesis and hematopoiesis but is also expressed in certain tumors. This systematic review examines the potential role of TLE1 as a diagnostic biomarker for the synovial sarcoma. Materials and Methods. A literature review and meta-analysis were conducted using the electronic databases Pubmed, the Cochrane Library, and Google Scholar. Thirteen studies met our eligibility criteria and were selected for in-depth analysis. Results. The mean sensitivity and specificity of TLE1 in detecting synovial sarcoma were 94% (95% CI 91%–97%) and 81% (95% CI 72%–91%), respectively, when all studies were aggregated together. The mean positive predictive value (PPV) of TLE1 was 75% (95% CI 62%–87%), whereas the negative predictive value (NPV) was 96% (95% CI 93%–98%). Conclusion. TLE1 is a sensitive and specific marker for synovial sarcoma that can aid in its diagnosis. Due to its involvement in several relevant signaling pathways, TLE1 might have direct relevance to the pathophysiology of the disease.

scholarly journals B waves: a systematic review of terminology, characteristics, and analysis methods

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Isabel Martinez-Tejada ◽  
Alexander Arum ◽  
Jens E. Wilhjelm ◽  
Marianne Juhler ◽  
Morten Andresen
Keyword(s):  
Systematic Review ◽  
Intracranial Pressure ◽  
Literature Search ◽  
Search Strategy ◽  
Morphological Characteristics ◽  
Systematic Review Protocol ◽  
Eligibility Criteria ◽  
Wave Characteristics ◽  
Search Terms ◽  
Review Protocol

Abstract Background Although B waves were introduced as a concept in the analysis of intracranial pressure (ICP) recordings nearly 60 years ago, there is still a lack consensus on precise definitions, terminology, amplitude, frequency or origin. Several competing terms exist, addressing either their probable physiological origin or their physical characteristics. To better understand B wave characteristics and ease their detection, a literature review was carried out. Methods A systematic review protocol including search strategy and eligibility criteria was prepared in advance. A literature search was carried out using PubMed/MEDLINE, with the following search terms: B waves + review filter, slow waves + review filter, ICP B waves, slow ICP waves, slow vasogenic waves, Lundberg B waves, MOCAIP. Results In total, 19 different terms were found, B waves being the most common. These terminologies appear to be interchangeable and seem to be used indiscriminately, with some papers using more than five different terms. Definitions and etiologies are still unclear, which makes systematic and standardized detection difficult. Conclusions Two future lines of action are available for automating macro-pattern identification in ICP signals: achieving strict agreement on morphological characteristics of “traditional” B waveforms, or starting a new with a fresh computerized approach for recognition of new clinically relevant patterns.

scholarly journals Performance of host blood transcriptomic signatures for diagnosing and predicting progression to tuberculosis disease in HIV-negative adults and adolescents: a systematic review protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e026612 ◽  
Author(s):  
Humphrey Mulenga ◽  
Erick Wekesa Bunyasi ◽  
Stanley Kimbung Mbandi ◽  
Simon C Mendelsohn ◽  
Benjamin Kagina ◽  
...  
Keyword(s):  
Systematic Review ◽  
Messenger Rna ◽  
Literature Search ◽  
Meta Analysis ◽  
Systematic Review Protocol ◽  
Cross Sectional ◽  
Review Protocol ◽  
Randomised Controlled ◽  
Host Blood ◽  
True False

IntroductionOne-quarter of the global population, including the majority of adults in tuberculosis (TB) endemic countries, are estimated to beMycobacterium tuberculosis(MTB) infected. An estimated 10 million new TB cases occurred in 2017. One of the biggest challenges confronting TB control is the lack of accurate diagnosis and prediction of prevalent and incident TB disease, respectively. Several host blood transcriptomic messenger RNA (mRNA) signatures that reflect the host immune response following infection with MTB and progression to TB disease in different study populations have recently been published, but these TB biomarkers have not been systematically described. We will conduct a systematic review of the performance of host blood transcriptional signatures for TB diagnosis and prediction of progression to TB disease.Methods and analysisThis systematic review will involve conducting a comprehensive literature search of cohort, case–control, cross-sectional and randomised-controlled studies of the performance of host blood transcriptomic signatures for TB diagnosis and prediction of progression to TB disease. We will search Medline via PubMed, Scopus, Web of Science and EBSCO libraries, complemented by a search of bibliographies of selected articles for other relevant articles. The literature search will be restricted to studies published in English from 2005 to 2018 and conducted in HIV-uninfected adults and adolescents (≥12 years old). Forest plots and a narrative synthesis of the findings will be provided. The primary outcomes will be sensitivity, specificity, as well as true/false positives and true/false negatives. Heterogeneity resulting from differences in the design, composition and structure of individual signatures will preclude meta-analysis and pooling of results.Ethics and disseminationEthics approval is not required for this systematic review protocol. The results of this review will be disseminated through a peer-reviewed journal as well as conference presentations.PROSPERO registration numberCRD42017073817.

scholarly journals Safety and efficiency of gasless laparoscopy: a systematic review protocol

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Haitham Shoman ◽  
Simone Sandler ◽  
Alexander Peters ◽  
Ameer Farooq ◽  
Magdalen Gruendl ◽  
...  
Keyword(s):  
Systematic Review ◽  
Assessment Tool ◽  
Data Extraction ◽  
Meta Analysis ◽  
A Priori ◽  
Risk Of Bias ◽  
Conventional Laparoscopy ◽  
Eligibility Criteria ◽  
Gasless Laparoscopy ◽  
Resource Setting

Abstract Background Gasless laparoscopy, developed in the early 1990s, was a means to minimize the clinical and financial challenges of pneumoperitoneum and general anaesthesia. It has been used in a variety of procedures such as in general surgery and gynecology procedures including diagnostic laparoscopy. There has been increasing evidence of the utility of gasless laparoscopy in resource limited settings where diagnostic imaging is not available. In addition, it may help save costs for hospitals. The aim of this study is to conduct a systematic review of the available evidence surrounding the safety and efficiency of gasless laparoscopy compared to conventional laparoscopy and open techniques and to analyze the benefits that gasless laparoscopy has for low resource setting hospitals. Methods This protocol is developed by following the Preferred Reporting Items for Systematic review and Meta-Analysis–Protocols (PRISMA-P). The PRISMA statement guidelines and flowchart will be used to conduct the study itself. MEDLINE (Ovid), Embase, Web of Science, Cochrane Central, and Global Index Medicus (WHO) will be searched and the National Institutes of Health Clinical Trials database. The articles that will be found will be pooled into Covidence article manager software where all the records will be screened for eligibility and duplicates removed. A data extraction spreadsheet will be developed based on variables of interest set a priori. Reviewers will then screen all included studies based on the eligibility criteria. The GRADE tool will be used to assess the quality of the studies and the risk of bias in all the studies will be assessed using the Cochrane Risk assessment tool. The RoB II tool will assed the risk of bias in randomized control studies and the ROBINS I will be used for the non-randomized studies. Discussion This study will be a comprehensive review on all published articles found using this search strategy on the safety and efficiency of the use of gasless laparoscopy. The systematic review outcomes will include safety and efficiency of gasless laparoscopy compared to the use of conventional laparoscopy or laparotomy. Trial registration The study has been registered in PROSPERO under registration number: CRD42017078338

scholarly journals Association between bipolar spectrum disorder and bone health: a meta-analysis and systematic review protocol

BMJ Open ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. e013981 ◽  
Author(s):  
Vinoomika Chandrasekaran ◽  
Sharon L Brennan-Olsen ◽  
Amanda L Stuart ◽  
Julie A Pasco ◽  
Michael Berk ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bone Health ◽  
Meta Analysis ◽  
Spectrum Disorder ◽  
Bipolar Spectrum ◽  
Systematic Review Protocol ◽  
Bipolar Spectrum Disorder ◽  
Review Protocol

scholarly journals Effectiveness of Auricular Acupuncture in Treating Depressive Disorders: a Systematic Review Protocol

2021 ◽  
Author(s):  
Karla Natally Santos ◽  
Mayk Rodolfo de Jesus Santana ◽  
Giselle de Carvalho Brito ◽  
Luciana Pereira Lobato
Keyword(s):  
Systematic Review ◽  
Depressive Disorder ◽  
Systematic Reviews ◽  
Depressive Disorders ◽  
Functional Disability ◽  
Meta Analysis ◽  
Auricular Acupuncture ◽  
World Population ◽  
Systematic Review Protocol ◽  
Review Protocol

Abstract Background: Depression is a chronic condition of high prevalence in the world population and associated with functional disability and compromises the physical health of affected individuals. According to Traditional Chinese Medicine (TCM), depression is associated with disability, there is not enough energy for positive feelings or associated with stagnation, when there is energy, but the flow of energy and emotions is blocked. Deficiency is also associated with excess in manic depression or irregularity in depression associated with anxiety. Auricular acupuncture, also known as auriculotherapy, it is part of a set of techniques based on TCM. For this, the auricular pavilion is related to 12 meridians, stimulating points in the ear and restoring the balance between blood and Qi (energy or vital force).Methods: This is a systematic review protocol for clinical trials prepared in accordance with the guidelines of the protocol Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA-P). Studies in which participants have any depressive disorder, diagnosed through standardized criteria such as the Diagnostic and Statistical Manual of Mental Disorders (DSM), the International Classification of Diseases (ICD) and other diagnostic criteria used internationally will be included. There will be no restrictions on age, gender, ethnicity, education or economic status. Studies will be accepted that have as experimental intervention any type of auricular acupuncture (using needles, seeds, magnetic stones, lasers, ultrasound, bleeding or electrical treatment). The control interventions that will be considered for the studies will be conventional medical treatment for each depressive disorder, no treatment, placebo and other active therapies. Discussion: Auricular acupuncture can be a potential alternative complementary treatment, it is low cost and has minimal side effects presented until now. With this review we hope to complete gaps in the knowledge of auricular acupuncture, promoting an updated and comprehensive synthesis of research on this topic. Record of systematic review: In accordance with the guidelines, our systematic review protocol was registered with the International Prospective Registry of systematic reviews (PROSPERO) on 10/27/2020 (registration number CRD42020211302).

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