scholarly journals Ocimum basilicum (kemangi) intervention on powder and microencapsulated Spirulina platensis and its bioactive molecules

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 485
Author(s):  
Y Yuliani ◽  
Putut Har Riyadi ◽  
Eko Nurcahya Dewi ◽  
Irwandi Jaswir ◽  
Tri Winarni Agustini
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Spirulina Platensis ◽  
Encapsulation Efficiency ◽  
Control Sample ◽  
Pharmaceutical Product ◽  
Ocimum Basilicum ◽  
Total Phenol ◽  
Bioactive Molecules ◽  
Drying Methods

Background: Spirulina platensis contains several bioactive molecules such as phenol, flavonoid and phycocyanin pigments. This study unveils total phenol, flavonoid, antioxidant activity, phycocyanin content and evaluated encapsulation efficiency from Ocimum basilicum intervention on S. platensis. O. basilicum intervention aims to reduce unpleasant odors from S. platensis that will increase consumption and increase bioactive compounds.   Methods: The intervention was carried out by soaking a S. platensis control sample (SP) in O. basilicum with a ratio of 1:4 (w/v) and it was then dried (DSB) and microencapsulated by freeze drying methods (MSB) using a combination of maltodextrin and gelatin. Total flavonoid and phenolic analysis with curve fitting analysis used a linear regression approach. Antioxidant activity of samples was analysed with the 2,2’-azino-bis-3-3thylbenzthiazoline-6-sulphonic acid (ABTS) method. Data were analysed using ANOVA at significance level (p < 0.05) followed by Tukey test models using SPSS v.22.  Results: The result of this study indicated that O. basilicum intervention treatment (DSB) has the potential to increase bioactive compounds such as total phenol, antioxidant activity and phycocyanin, and flavonoid content. Intervention of O. basilicum on S. platensis (DSB) significantly increases total phenol by 49.5% and phycocyanin by 40.7%. This is due to the phenol and azulene compounds in O. basilicum which have a synergistic effect on phenol and phycocyanin in S. platensis. Microencapsulation using a maltodexrin and gelatin coating is effective in phycocyanin protection and antioxidant activity with an encapsulation efficiency value of 71.58% and 80.5%.   Conclusion: The intervention of O. basilicum on S. platensis improved the total phenol and phycocyanin content and there is potential for a pharmaceutical product for a functional food and pharmaceutical product.

scholarly journals Ocimum basilicum (kemangi) intervention on powder and microencapsulated Spirulina platensis and its bioactive molecules

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 485
Author(s):  
Y Yuliani ◽  
Putut Har Riyadi ◽  
Eko Nurcahya Dewi ◽  
Irwandi Jaswir ◽  
Tri Winarni Agustini
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Spirulina Platensis ◽  
Encapsulation Efficiency ◽  
Control Sample ◽  
Ocimum Basilicum ◽  
Total Phenol ◽  
Bioactive Molecules ◽  
Drying Methods ◽  
Significance Level

Background: Spirulina platensis contains several bioactive molecules such as phenol, flavonoid and phycocyanin pigments. This study unveils total phenol, flavonoid, antioxidant activity, phycocyanin content and evaluated encapsulation efficiency from Ocimum basilicum intervention on S. platensis. O. basilicum intervention aims to reduce unpleasant odors from S. platensis that will increase consumption and increase bioactive compounds.   Methods: The intervention was carried out by soaking a S. platensis control sample (SP) in O. basilicum with a ratio of 1:4 (w/v) and it was then dried (DSB) and microencapsulated by freeze drying methods (MSB) using a combination of maltodextrin and gelatin. Total flavonoid and phenolic analysis with curve fitting analysis used a linear regression approach. Antioxidant activity of samples was analysed with the 2,2’-azino-bis-3-3thylbenzthiazoline-6-sulphonic acid (ABTS) method. Data were analysed using ANOVA at significance level (p < 0.05) followed by Tukey test models using SPSS v.22.  Results: The result of this study indicated that O. basilicum intervention treatment (DSB) has the potential to increase bioactive compounds such as total phenol, antioxidant activity and phycocyanin, and flavonoid content. Intervention of O. basilicum on S. platensis (DSB) significantly increases total phenol by 48.7% and phycocyanin by 40.7%. This is due to the phenol and azulene compounds in O. basilicum which have a synergistic effect on phenol and phycocyanin in S. platensis. Microencapsulation using a maltodexrin and gelatin coating is effective in phycocyanin protection with an encapsulation efficiency value of 71.58%.   Conclusion: The intervention of O. basilicum on S. platensis improved the total phenol and phycocyanin content and there is potential for a pharmaceutical product.

scholarly journals PENGARUH METODE PENGERINGAN TERHADAP KADAR SENYAWA BIOAKTIF DAN AKTIVITAS ANTIOKSIDAN PADA HERBA SURUHAN (Peperomia pellucida L.)

2021 ◽  
Vol 6 (2) ◽  
pp. 302-311
Author(s):  
Dewi Puspita Apsari ◽  
◽  
Muhammad Nanda Aprilianto ◽  
Ni Luh Desyani ◽  
Ni Putu Widayanti ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Total Phenol ◽  
Drying Methods ◽  
Total Flavonoids ◽  
Total Phenols ◽  
Direct Sunlight ◽  
Oven Drying ◽  
Bioactive Content

Suruhan herb have been used globally as concoction for medical and therapeutic purposes, so that it is much needed to investigate their phytonutrients. The variations in drying methods can affect the levels of bioactive compounds and antioxidant activity, so an appropriate drying strategy is needed to produce simplicia that containing high bioactive compounds and antioxidant activity. Based on the considerations above, this study aimed to determine the effect of various drying methods strategies (direct sunlight, oven drying and wind drying) on the bioactive compounds and antioxidant activity of the suruhan herb. The extract of suruhan herb were subsequently analyzed for total flavonoids, total phenols, total tannins, and their antioxidant activity. The results showed that oven-dried suruhan herb produced the highest potential antioxidant activity, that was 94.67 ppm with total flavonoids 51.00 mgQE/g extract, total phenol 63.36 mgGAE/g extract, and total tannins 41.89 mgTAE/g extract. It can be concluded that the variety of drying strategy has a significant impact (p<0.05) on the bioactive content and antioxidant activity of the suruhan herb.

scholarly journals Encapsulation of Soursop (Annona muricata Linn.) Leaf Tea Extract Using Natural Mucilage

REAKTOR ◽  
2019 ◽  
Vol 19 (1) ◽  
pp. 26-33
Author(s):  
Melanie Cornelia ◽  
Kam Natania ◽  
Herry Cahyana ◽  
Edison Sutiyono
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Encapsulation Efficiency ◽  
Aloe Vera ◽  
Bioactive Molecules ◽  
Total Phenolic ◽  
Coating Materials ◽  
Before And After ◽  
Materials Used ◽  
Tea Extract

The bioactively rich soursop leaf extract can be encapsulated inside several natural coating materials. The extract of soursop leaf has been found to contain many bioactive compounds such as various phenolic compounds that are beneficial for anticancer, antidiabetic and many other health benefits. However due to the sensitive nature of the bioactive molecules, encapsulation procedure was applied to prolong the activity of the biomolecules. Capsule materials used in this experiment were obtained from natural extract of Okra mucilage, Aloe vera mucilage and Maltodextrin-WPI mixture to protect the unstable bioactive compounds. Homogenation time using ultrasonication and Core to Coating ratio was differed to observe the optimum encapsulation process. The encapsulation efficiency, release factor ability, size distribution and its correlation with bioactive stability are observed using Total Phenolic methods and Antioxidant Activity before and after encapsulation. Aloe vera gave best encapsulation efficiency (88-91%) while microcapsule made with Okra gave the best antioxidant activity (DPPH IC50 633-710ppm), and maltodextrin-WPI gave best powder recovery (yield 70-73%). Keywords: aloe mucilage, antioxidant activity,  encapsulation, okra mucilage, soursop tea extract

scholarly journals Ultrasound and Microwave Assisted Extraction of Opuntia Fruit Peels Biocompounds: Optimization and Comparison Using RSM-CCD

Molecules ◽  
2019 ◽  
Vol 24 (19) ◽  
pp. 3618 ◽  
Author(s):  
Bruno Melgar ◽  
Maria Inês Dias ◽  
Lillian Barros ◽  
Isabel C.F.R. Ferreira ◽  
Antonio D. Rodriguez-Lopez ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Bioactive Molecules ◽  
Specific Response ◽  
Microwave Assisted Extraction ◽  
Ultrasound Assisted Extraction ◽  
Microwave Assisted ◽  
Assisted Extraction ◽  
Ic50 Values ◽  
Effective Models

Ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE) of bioactive compounds, peels from Opuntia engelmannii cultivar (cv.) Valencia were optimized by response surface methodology. Randomized extraction runs were performed for each of the technologies employed in order to build effective models with maximum (bioactive molecules content and yield) and minimum (antioxidant activity) responses. A 5-level, 4-factor central composite design was used to obtain target responses as a function of extraction time (t), solid to liquid ratio (S/L), methanol concentration (metOH), and temperature (T). Specific response optimization for each technology was analyzed, discussed, and general optimization from all the responses together was also gather. The optimum values for each factor were: t = 2.5 and 1.4 min, S/L = 5 and 5 g/L, metOH = 34.6 and 0% of methanol and T = 30 and 36.6 °C, achieving maximum responses of 201.6 and 132.9 mg of betalains/g, 13.9 and 8.0 mg of phenolic acids/g, 2.4 and 1.5 mg of flavonoids/g, 71.8% and 79.1% of extractable solid and IC50 values for the antioxidant activity of 2.9 and 3.6, for UAE and MAE, respectively. The present study suggested UAE as the best extraction system, in order to maximize recovery of bioactive compounds with a high antioxidant activity.

Microcapsules of Cajá-manga (Spondias dulcis Parkinson): Influence of Different Types of Encapsulating Agents and Drying Technology

2019 ◽  
Vol 15 (6) ◽  
pp. 557-564
Author(s):  
Suelen S. dos Santos ◽  
Letícia M. Rodrigues ◽  
Vicelma L. Cardoso ◽  
Miria H.M. Reis ◽  
Grasiele S. Madrona
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Compounds ◽  
Vitamin A ◽  
Xanthan Gum ◽  
Encapsulation Efficiency ◽  
Physicochemical Analysis ◽  
Drying Methods ◽  
Spray Dryer ◽  
Different Types ◽  
Drying Technology

Background: Cajá-manga is an exotic fruit, source of compounds that have antioxidant activity, such as pro-vitamin A and carotenoids. Objective: Thus, the objective of the present study was to develop an efficient microencapsulation process for cajá-manga pulp by different types of encapsulating agents (maltodextrin and xanthan gum), ratio pulp/carrier agents (1:2 or 1:5), and the drying technology (lyophilization and spray dryer). Methods: Physicochemical analysis, phenolic compounds, carotenoids, antioxidant activity and microcapsule morphology were performed. Results: The cajá-manga and its microcapsulas can be considered source of phenolic compounds, carotenoides and antioxidants. The morphology showed differences between the both drying methods, with encapsulation efficiency greater than 70% in 1:2 (w/w) ratio, and efficiencies around 40% with 1:5 (w/w) pulp and carrier agent. Conclusion: The use of maltodextrin and xanthan gum showed to be viable in the spray dryer and lyophilization drying processes.

scholarly journals Design of Healthy Snack Based on Kiwifruit

Molecules ◽  
2020 ◽  
Vol 25 (14) ◽  
pp. 3309 ◽  
Author(s):  
Urszula Tylewicz ◽  
Malgorzata Nowacka ◽  
Katarzyna Rybak ◽  
Kinga Drozdzal ◽  
Marco Dalla Rosa ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Vitamin C ◽  
Bioactive Compounds ◽  
Freeze Drying ◽  
Bioactive Compound ◽  
Convective Drying ◽  
Drying Methods ◽  
Hot Air ◽  
Sugar Addition ◽  
High Antioxidant Activity

Kiwifruit is an excellent source of vitamin C and other bioactive compounds, which contribute to its high antioxidant activity. However, the fruits with small size and low weight are considered waste and are unprofitable; therefore, the production of healthy kiwifruit-based dried snacks, which contain a lot of health-beneficial ingredients, could be a viable alternative for their use. The aim of this study was to develop formulations and methods to produce attractive and nutritionally valuable dried snacks based on yellow kiwifruit. Three different puree formulations (kiwifruit; fennel; and strawberry, lemon, or spinach) with or without addition of sugar were subjected to two drying methods: freeze-drying (fruit bars) and conventional hot air drying (fruit leathers). The obtained products were analysed for their content of total polyphenols (TPs), flavonoids, and vitamin C, as well as their antioxidant activity. The results showed that snacks prepared by freeze-drying (fruit bars) presented higher TP, vitamin C, and flavonoids content than those prepared by convective drying; however, the antioxidant activity did not always follow this trend. The amount of bioactive compounds depended on the formulation used for the preparation of snacks. The effect of the sugar addition seems to be strictly related to the mix used and specific bioactive compound investigated.

scholarly journals Characterisation of an Aromatic Plant-based Formula using UV-Vis Spectroscopy, LC–ESI(+)QTOF-MS and HPLC-DAD Analysis

2013 ◽  
Vol 70 (1) ◽  
pp. 16 ◽  
Author(s):  
Florina Bunghez ◽  
Carmen Socaciu ◽  
Florina Zagrean ◽  
Raluca Maria Pop ◽  
Floricuta Ranga ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Biological Effects ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
New Product ◽  
Bioactive Molecules ◽  
Accurate Information ◽  
Vis Spectroscopy ◽  
The Individual

Abstract. It is known for a long time that seasoning/condimentary herbs have antioxidant activity and antibacterial properties, being good natural alternatives for disease prevention. The different efficiency of these plants is assigned to their bioactive molecules, stability and bioavailability. In the present study seven aromatic herbs (basil, thyme, oregano, rosemary, clove, cinnamon and sage) were investigated individually. A new product was developed using basil, thyme, oregano, rosemary, clove, cinnamon and sage, according to a default recipe. The characterization of each plant aimed to identify the specific “fingerprint” by its main bioactive molecules and the “traceability” of these molecules in the new product, made by mixing the selected plants according to a default recipe. In order to determine the main bioactive compounds of the individual plants composition, in comparison with the new plant-based (EPC) formula, high throughput techniques like UV-Vis spectroscopy and LC-QTOF-MS  spectrometry were used. The most important bioactive compounds determined in the studied herbs, which may exert antioxidant activity and antibacterial properties, were phenolic compounds (phenolic acids, flavonoids), quinones, clorophylls as well some polar terpenoids. The fingerprints are providing comprehensive and accurate information about the compounds that may exert antimicrobial properties. In order to assure the biological effects and the bioavailability of the polyphenols and the secondary metabolites we have to consider the antagonistic and synergistic effect that the metabolites can exert on each other.

scholarly journals ANTIOXIDANT ACTIVITY AND ISOLATION BIOACTIVE COMPOUNDS FROM ROSELLE (HIBISCUS SABDARIFFA) FROM VARIOUS METHODS AND DRYING TIME

AGROINTEK ◽  
2019 ◽  
Vol 13 (1) ◽  
pp. 1
Author(s):  
Ike Sitoresmi mulyo Purbowati ◽  
Sujiman Sujiman ◽  
Ali Maksum
Keyword(s):  
Antioxidant Activity ◽  
Vitamin C ◽  
Bioactive Compounds ◽  
Drying Methods ◽  
Hibiscus Sabdariffa ◽  
Drying Time ◽  
Radical Trapping ◽  
Direct Exposure ◽  
Total Anthocyanins ◽  
Antioxidant Agent

The focus of this study was to evaluate the effect of different drying methods and drying level on the bioactive compounds of roselle (Hibiscus sabdariffa L.)as antioxidant agent. The experiment has been conducted in cabinet dryer and by a direct exposure on sun light as weel as by using a green house effect panel with duration of driying: 1, 3, 5, 7 hours. The observed parameters were Colour, levels of anthocyanins,vitamin C, and free radical trapping capacity (DPPH). The data obtained were analyzed using analysis of variance (ANOVA) and further test DMRT (Duncant Multiple Range Test). The best results from these study was the cabinet drying with 7 h of drying time which have value for color (L, a*, b*), total anthocyanins, vitamin C, and antioxidant activity in respective order were 21.633; 6.80; 4.53; 3.22mg/100g; 1238.29mg/100g; 74,63%.

Sign in / Sign up

Export Citation Format

Share Document