scholarly journals Recent advances in managing primary hypertension

2020 ◽  
Vol 9 ◽  
Author(s):  
Ioannis Leontsinis ◽  
Manos Mantzouranis ◽  
Panagiotis Tsioufis ◽  
Ioannis Andrikou ◽  
Costas Tsioufis
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Measurement ◽  
Treatment Options ◽  
Initial Assessment ◽  
Antihypertensive Medications ◽  
Optimal Method ◽  
Mortality And Morbidity ◽  
Novel Treatment ◽  
Individualized Approach ◽  
Patient Groups

Hypertension remains a leading risk factor for cardiovascular mortality and morbidity globally despite the availability of effective and well-tolerated antihypertensive medications. Accumulating evidence suggests a more aggressive blood pressure regulation aimed at lower targets, particularly for selected patient groups. Our concepts of the optimal method for blood pressure measurement have radically changed, maintaining appropriate standard office measurements for initial assessment but relying on out-of-office measurement to better guide our decisions. Thorough risk stratification provides guidance in decision making; however, an individualized approach is highly recommended to prevent overtreatment. Undertreatment, on the other hand, remains a major concern and is mainly attributed to poor adherence and resistant or difficult-to-control forms of the disease. This review aims to present modern perspectives, novel treatment options, including innovative technological applications and developing interventional and pharmaceutical therapies, and the major concerns emerging from several years of research and epidemiological observations related to hypertension management.

Acute Pancreatitis in Pregnancy: Maternal and Fetal Outcomes

2017 ◽  
Vol 9 (2) ◽  
pp. 106-109
Author(s):  
Asha Swarup ◽  
GS Jyothi ◽  
Shruti R Bhoosanoor
Keyword(s):  
Acute Pancreatitis ◽  
Epigastric Pain ◽  
Treatment Options ◽  
Abdominal Cavity ◽  
Age At Onset ◽  
Initial Assessment ◽  
Fetal Mortality ◽  
Fetal Outcomes ◽  
Mortality And Morbidity ◽  
In Pregnancy

ABSTRACT Aim and objective To evaluate the maternal and fetal outcomes in patients with acute pancreatitis. Materials and methods It is a retrospective observational study. A total of three patients were admitted with acute pancreatitis complicating pregnancy between January 2013 and June 2015 in the Department of Obstetrics and Gynaecology, M. S. Ramaiah Medical College and Hospital, Bengaluru, India, and were followed up until after delivery. Results Incidence of acute pancreatitis in our study was 1 in 1,620. Mean age was 24 years, and 33.3% were multiparous. Mean gestational age at onset was 33 weeks. One patient (33.3%) in our study had hypertriglyceridemia (870 mg/dL), and 66.7% of patients were idiopathic. The most common complaint was epigastric pain radiating to back. All patients showed leukocytosis and elevated amylase and lipase levels. Ultrasound showed [1] enlarged pancreas with decreased peripancreatic echogenicity and [2] pelvic and abdominal cavity effusions, in all the patients. All patients were managed conservatively in the intensive care unit. Mean duration of hospital stay was 7 days; 33.3% patients developed acute respiratory distress syndrome; 33.3% patients went into preterm spontaneous vaginal delivery. Cesarean section rate was 66.7%. Perinatal mortality was 33.3%. Conclusion Acute pancreatitis in pregnancy remains a challenging clinical problem to manage. The initial assessment, severity, and the initial management of the patient are of great importance in order to support the function and to prevent maternal and fetal mortality and morbidity. Clinical significance Acute pancreatitis either in its mild or its severe form causes maternal and fetal morbidity. However, these rates are declining due to early diagnosis and greater treatment options. Multidisciplinary approach leads to good maternal and fetal outcomes. How to cite this article Jyothi GS, Bhoosanoor SR, Swarup A. Acute Pancreatitis in Pregnancy: Maternal and Fetal Outcomes. J South Asian Feder Obst Gynae 2017;9(2):100-103.

scholarly journals May Measurement Month 2018: an analysis of blood pressure screening results from Italy

2020 ◽  
Vol 22 (Supplement_H) ◽  
pp. H70-H73
Author(s):  
Camilla Torlasco ◽  
Andrea Faini ◽  
Claudio Ferri ◽  
Guido Grassi ◽  
Massimo Salvetti ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Health Care ◽  
Blood Pressure Measurement ◽  
Positive Trend ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Hypertension Awareness ◽  
Wide Scale ◽  
Definition Of

Abstract Cardiovascular (CV) diseases are burdened by high mortality and morbidity, being responsible for half of the deaths in Europe. Although hypertension is recognized as the most important CV risk factor, hypertension awareness and blood pressure (BP) control are still unsatisfactory. In 2017, 30.6% of a >10 000 individual sample who took part in the May Measurement Month (MMM) campaign in Italy was found to have high BP. To raise awareness on the hypertension issue and to report BP data on a nation-wide scale in Italy. In the frame of the MMM campaign, an opportunistic cross-sectional survey of volunteers aged ≥18 was carried out in May 2018. Blood pressure measurement, the definition of hypertension and statistical analysis followed the standard MMM protocol. Screenings were conducted in multiple sites by health care personnel. Among the 5554 people screened (females: 48.3%, mean age 58 ± 17 years) mean BP was 127/77 mmHg, and after imputations, 1462 (26.3%) participants were found to have high BP levels. Body mass index >25 was associated with higher systolic BP and diastolic BP (DBP), while diabetes was associated with high DBP only. Our data provide a nation-wide snapshot of BP control in a sample of individuals participating in a national health care campaign, and confirm the power of this kind of healthcare-related activities in reaching a significant number of people to raise awareness on health topics. The apparent positive trend in BP control compared to available data from other similar campaigns carried out during the past years needs to be confirmed with more methodologically robust studies.

scholarly journals Prevalence of Hypertension and Diabetes Mellitus among Haemodialysis Patients at Elobied Haemodialysis Unit –West Sudan

2019 ◽  
pp. 1-5
Author(s):  
Abdelsalam Mohamed Hamed Elfaki ◽  
Samia Tarig Abdalla Mohamed
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Insulin Therapy ◽  
Blood Pressure Measurement ◽  
Diabetic Patients ◽  
Chronic Haemodialysis ◽  
Antihypertensive Medications ◽  
Cross Sectional ◽  
Female Ratio ◽  
Hypertensive Patients

Background and Objectives: Hypertension and diabetes mellitus are major risk factors of end – stage renal disease (ESRD). This study aimed to determine the prevalence of hypertension and diabetes mellitus among haemodialysis patients at Elobeid haemodialysis unit. Patients and Methods: The study was a single – centre cross - sectional study including 130 patients on chronic haemodialysis in Elobeid hospital haemodialysis unit. Each patient was personally interviewed by the co-author in the haemodialysis unit using a structured questionnaire prepared by the investigators. Data collected include: socioeconomic data (gender, age, residence, and occupation), history of hypertension, diabetes mellitus, treatment of hypertension, treatment of diabetes mellitus, duration of hypertension, duration of diabetes mellitus and duration of dialysis. Hypertension was defined as blood pressure ≥ 140/90 or the use of antihypertensive medications. Diabetes mellitus is defined by use of insulin therapy. In this study both hypertension and diabetes mellitus were already diagnosed and on regular medications. Statistic package for social sciences (SPSS) version 20 was used for data analysis. Results: One hundred and thirty patients were recruited. More than two thirds of patients were males with male to female ratio of 2.2: 1. Patient’s age ranged from 12 years to 90 years. The mean age was 46.3 ± 17.8 years. Forty (32%) patients were above 56 years of age. Ninety eight (75%) patients were hypertensive, the majority of hypertensive patients were males (90%). Eighty six hypertensive patients were on calcium channel blocker (88%). Amlodipine was the commonly used antihypertensive used. Twenty five (19%) patients were diabetics and all of them were males. All diabetic patients were also hypertensive. Fourteen diabetic patients (56%) were on insulin therapy, while 11 patients were using metformin. Conclusion: The prevalence of hypertension among haemodialysis patients was high while the prevalence of diabetes is less than that reported globally. The blood pressure should be tidily controlled specially in diabetic patients and patients with impaired renal function. For early detection of chronic kidney disease and elevated blood pressure as a sequel, routine blood pressure measurement is highly recommended in adult patients attend the clinic for any reason.

scholarly journals Host-Directed Therapy as a Novel Treatment Strategy to Overcome Tuberculosis: Targeting Immune Modulation

Antibiotics ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 21 ◽  
Author(s):  
Sultan Ahmed ◽  
Rubhana Raqib ◽  
Guðmundur Hrafn Guðmundsson ◽  
Peter Bergman ◽  
Birgitta Agerberth ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Immune Modulation ◽  
Treatment Options ◽  
Lung Pathology ◽  
Current Standard ◽  
Mortality And Morbidity ◽  
Immune Mechanisms ◽  
Novel Treatment ◽  
Long Term Treatment ◽  
Mdr Tb

Tuberculosis (TB) is one of the leading causes of mortality and morbidity, particularly in developing countries, presenting a major threat to the public health. The currently recommended long term treatment regimen with multiple antibiotics is associated with poor patient compliance, which in turn, may contribute to the emergence of multi-drug resistant TB (MDR-TB). The low global treatment efficacy of MDR-TB has highlighted the necessity to develop novel treatment options. Host-directed therapy (HDT) together with current standard anti-TB treatments, has gained considerable interest, as HDT targets novel host immune mechanisms. These immune mechanisms would otherwise bypass the antibiotic bactericidal targets to kill Mycobacterium tuberculosis (Mtb), which may be mutated to cause antibiotic resistance. Additionally, host-directed therapies against TB have been shown to be associated with reduced lung pathology and improved disease outcome, most likely via the modulation of host immune responses. This review will provide an update of host-directed therapies and their mechanism(s) of action against Mycobacterium tuberculosis.

Evaluation of two methods of teaching blood pressure measurement

1988 ◽  
Vol 52 (9) ◽  
pp. 519-521
Author(s):  
NK Nordstrom ◽  
S Longenecker ◽  
HL Whitacre ◽  
FM Beck
Keyword(s):  
Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Measurement

EFEKTIVITAS PEMBERIAN HYDROTHERAPI RENDAM KAKI PADA PENDERITA HIPERTENSI DI BANJAR SRI MANDALA, KELURAHAN DAUHWARU KABUPATEN JEMBRANA

2019 ◽  
Vol 10 (01) ◽  
pp. 33-44
Author(s):  
N.L.G. Sudaryati ◽  
I P. Sudiartawan ◽  
Dwi Mertha Adnyana
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Measurement ◽  
Reduce Blood Pressure ◽  
Second Grade ◽  
Control Group ◽  
Hypertensive Patients ◽  
First Category

The aim of the study was to determine the effectiveness of giving hydrotherapi foot soak in hypertensive patients. The study was conducted with one group pretestposttest design without a control group by measuring blood pressure (pretest) before being given an intervention in the form of foot soak hydrotherm against 15 people with hypertension in Banjar Sri Mandala, Dauhwaru Village, Jembrana Subregency. Then do the blood pressure measurement again (posttest) after finishing the intervention. After the study was completed, the results showed that before the hydrotherapi foot bath intervention, there were 0% of patients classified as normal, 13.32% in prehypertension category, 60.08% in hypertension category I and 26.60% in hypertension category II. After the intervention was given, there were 13.32% of the patients classified as normal, 66.68% in the prehypertension category, 20.00% in the first category of hypertension and no patients belonging to the second grade hypertension category. There is a decrease of 20-30 mmHg for systolic blood pressure and 0-10 mmHg for diastolic blood pressure after intervention. Based on the results of the study it can be concluded that the hydrotherapi foot bath is effectively used to reduce blood pressure in hypertensive patients in the Banjar Sri Mandala, Dauhwaru Village, Jembrana District.

Study on Cuff-Less Blood Pressure Measurement Based on Electrocardiography and Photoplethysmography Signal

2019 ◽  
Vol 2 (3) ◽  
pp. 206-214
Author(s):  
Putri Indes Oktabriani ◽  
Fuad Ughi ◽  
Aulia Arif Iskandar
Keyword(s):  
Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Monitoring ◽  
Blood Pressure Measurement ◽  
Ecg Signal ◽  
Optimum Location ◽  
Blood Pressure Monitor ◽  
Pressure Monitor ◽  
Left Hand ◽  
Measure Blood Pressure

The continuous blood pressure measurement research is widely known for helpingthe development of ambulatory blood pressure monitoring where it measures blood pressureevery 15 to 30 minutes throughout the day. The cuff is a problem for the patient withAmbulatory Blood Pressure Monitor. It can make a person feel uncomfortable and must staystill when the cuff starts to inflate. It is limiting and disturbing their daily activity when thedevice is starting to measure the blood pressure. Blood pressure measurement without cuff isbeing proposed in this research, called cuff-less blood pressure measurement. It will be based onPhotoplethysmography (PPG) and Electrocardiography (ECG) signal analysis. ECG (Lead 1,Lead 2, and Lead 3) with PPG signal produced from index finger on the left hand are comparedand analyzed. Then the relation of PPG and ECG signal and the optimum location for daily usecan be obtained. The optimum location will be based on the electrode’s position that producedthe optimum ECG lead Signal to measure blood pressure. Based on the result, PPG and ECGsignal have a linear relation with Blood Pressure Measurement and Lead 1 is more stable inproducing the ECG signal. The equation from Lead 1 appeared as one of the optimum equationsfor measuring Systolic Blood Pressure (SBP) or Diastolic Blood Pressure (DBP).

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