Poria cocos ethanol extract and its active constituent, pachymic acid, modulate sleep architectures via activation of GABAA-ergic transmission in rats

2015 ◽  
Vol 16 (3) ◽  
pp. 84-92 ◽  
Author(s):  
funcVikash Kumar Shah ◽  
Sam-Shik Na ◽  
Myong-Soo Chong ◽  
Jae-Hoon Woo ◽  
Yeong-Ok Kwon ◽  
...  
Keyword(s):  
Ethanol Extract ◽  
Active Constituent ◽  
Poria Cocos ◽  
Pachymic Acid

scholarly journals ANTIANXIETY EFFECT OF ETHANOLIC EXTRACT OF FRUITS OF LIMONIA ACIDISSIMA IN SWISS ALBINO MICE

2021 ◽  
Vol 6 (8) ◽  
pp. 104-117
Author(s):  
Chouhan Vaishali ◽  
Sujane Sandhya ◽  
Bapna Rajendra ◽  
Pyathi Asharani
Keyword(s):  
Elevated Plus Maze ◽  
Treatment Options ◽  
Ethanolic Extract ◽  
Anxiolytic Effect ◽  
Ethanol Extract ◽  
Active Constituent ◽  
Swiss Albino Mice ◽  
Plus Maze ◽  
Albino Mice ◽  
Limonia Acidissima

Anxiety disorder is one of the most common mental ailments exhibited by human. It is characterized by motor tension, sympathetic hyperactivity and apprehension and vigilance syndromes. A part from very few chemical remedies available like benzodiazepine and serotonin modulators, not much treatment options are at hand that safely and effectively alleviate anxiety. The ethanol extract of the fruits of plant Limonia acidissima was evaluated for its anti-anxiety activity in swiss albino mice at dose 200mg/kg and 400mg/kg body weight. Anti-anxiety was assessed by using elevated plus maze (EPM) and light and dark model methods. The ethanolic extract exhibit anxiolytic effect in experimental mice. So it is supports the use of Limonia acidissima as anxiolytic agents. Further investigation should be made to elucidate the active constituent of responsible for the activity.

scholarly journals Antioxidant effect of ethanol extract from Poria cocos depending on cultivation methods

2016 ◽  
Vol 31 (5) ◽  
pp. 107-114 ◽  
Author(s):  
Yoo-Jin Kim ◽  
Hae-Jin Park ◽  
Jin Sang Lee ◽  
Eunju Do ◽  
Hyeong Rack Sohn ◽  
...  
Keyword(s):  
Ethanol Extract ◽  
Antioxidant Effect ◽  
Poria Cocos ◽  
Cultivation Methods

scholarly journals Nematicidal Activity of Holigarna caustica (Dennst.) Oken Fruit Is Due to Linoleic Acid

Biomolecules ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1043
Author(s):  
Sujogya Kumar Panda ◽  
Raju Das ◽  
Anh Hung Mai ◽  
Wim M. De Borggraeve ◽  
Walter Luyten
Keyword(s):  
Linoleic Acid ◽  
Model Organism ◽  
Anthelmintic Activity ◽  
Ethanol Extract ◽  
Traditional Healers ◽  
Northeast India ◽  
Nematicidal Activity ◽  
Active Constituent ◽  
C Elegans ◽  
Bioassay Guided Fractionation

Holigarna caustica (Dennst.) Oken is used by the tribes of Northeast India for the treatment of intestinal problems. Therefore, the present study was undertaken to investigate the active principles of this plant responsible for its anthelmintic activity, using bioassay-guided fractionation. An ethanol extract of H. caustica fruit was fractionated on a silica gel column, followed by HPLC, while nematicidal activity was followed throughout on Caenorhabditis (C.) elegans as a model organism. Our study constitutes the first nematicidal report for this plant. Bioassay-guided purification led to the isolation of one compound (IC50 = 0.4 µM) as the only active constituent in the most active fraction. The compound was identified as linoleic acid based on spectroscopic data (1H and 13C NMR and ESI-MS). No cytotoxicity was observed in the crude extract or in linoleic acid (up to 356 µM). The results support the use of H. caustica for the treatment of intestinal problems by traditional healers in India.

scholarly journals In Vivo Anti-tumor Effects of the Ethanol Extract of Gleditsia sinensis Thorns and Its Active Constituent, Cytochalasin H

2015 ◽  
Vol 38 (6) ◽  
pp. 909-912 ◽  
Author(s):  
Jin-Mu Yi ◽  
Jinhee Kim ◽  
Jong-Shik Park ◽  
Jun Lee ◽  
You Jin Lee ◽  
...  
Keyword(s):  
Ethanol Extract ◽  
Active Constituent ◽  
Gleditsia Sinensis

Triterpenes in the Ethanol Extract of Poria cocos Induce Dermal Papilla Cell Proliferation

2019 ◽  
Vol 16 (1) ◽  
pp. 1-9
Author(s):  
Chun-Chieh Wang ◽  
Lu-Kai Wang ◽  
Mao-Liang Chen ◽  
Chan-Yen Kuo ◽  
Fu-Ming Tsai ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Ethanol Extract ◽  
Dermal Papilla ◽  
Poria Cocos ◽  
Dermal Papilla Cell
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