scholarly journals The importance of vitamin D3 supplementation in orthopedics - literature review

2020 ◽  
Vol 10 (5) ◽  
pp. 118
Author(s):  
Dominik Machaj ◽  
Katarzyna Cyboran ◽  
Alicja Płaczek ◽  
Marlena Baran ◽  
Michał Wojnowski
Keyword(s):  
Literature Review ◽  
Vitamin D3 ◽  
Vitamin D3 Supplementation

scholarly journals The benefits of vitamin D3 supplementation for menopausal women - literature review

2021 ◽  
Vol 11 (6) ◽  
pp. 47-51
Author(s):  
Katarzyna Cyboran ◽  
Monika Kuc ◽  
Jakub Lis ◽  
Damian Machaj ◽  
Jakub Polak
Keyword(s):  
Literature Review ◽  
Vitamin D3 ◽  
Menopausal Women ◽  
Vitamin D3 Supplementation ◽  
Women Literature

Witamina D to potoczna nazwa cholekalcyferolu i ergokalcyferolu. Występuje w postaci nieaktywnej, ale w wyniku hydroksylacji w pozycji 1 lub 25 staje się witaminą aktywną. Cholekalcyferol paszy z nieaktywnej formy pod wydanie UV w ciało ciało, natomiast ergosterol jest dostarczany do organizmu z pożywienia roślinnego. Witamina D ma znaczący wpływ na zdrowie kobiet po menopauzie. Poziom estrogenu spada u kobiety w okresie menopauzy. Ma to konsekwencje m.in. ubytki wapnia. To jest powód, dla którego kobiety w tym wieku znajduje się w grupie ryzyka zachorowania na osteoporozę. Witamina D pomaga w przyswajaniu wapnia i fosforu. Te minerały pełnią wolę wolę w okresie menopauzy.Kobiety w tej grupie wiekowej przyjmować od 1000 do 1500 mg dziennie. Nie zaleca się nadmiernego spożycia, przekroczenie normy nie przynosi lepszych efektów. Mimo to wykrycie niedoboru witaminy D u kobiet po menopauzie i rozpoczęcie leczenia pozytywnie wpływ na ich stan zdrowia. [1]

scholarly journals Prevention of Advanced Cancer by Vitamin D3 Supplementation: Interaction by Body Mass Index Revisited

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1408
Author(s):  
Hermann Brenner ◽  
Sabine Kuznia ◽  
Clarissa Laetsch ◽  
Tobias Niedermaier ◽  
Ben Schöttker
Keyword(s):  
Body Mass Index ◽  
Vitamin D ◽  
Cancer Patients ◽  
Body Mass ◽  
Advanced Cancer ◽  
Vitamin D3 ◽  
Normal Weight ◽  
The Body ◽  
Published Data ◽  
Vitamin D3 Supplementation

Meta-analyses of randomized controlled trials (RCTs) have demonstrated a protective effect of vitamin D3 (cholecalciferol) supplementation against cancer mortality. In the VITAL study, a RCT including 25,871 men ≥ 50 years and women ≥ 55 years, protective effects of vitamin D3 supplementation (2000 IU/day over a median of 5.3 years) with respect to incidence of any cancer and of advanced cancer (metastatic cancer or cancer death) were seen for normal-weight participants but not for overweight or obese participants. We aimed to explore potential reasons for this apparent variation of vitamin D effects by body mass index. We conducted complementary analyses of published data from the VITAL study on the association of body weight with cancer outcomes, stratified by vitamin D3 supplementation. Significantly increased risks of any cancer and of advanced cancer were seen among normal-weight participants compared to obese participants in the control group (relative risk (RR), 1.27; 95% confidence interval (CI), 1.07–1.52, and RR, 1.44; 95% CI, 1.04–1.97, respectively). No such patterns were seen in the intervention group. Among those with incident cancer, vitamin D3 supplementation was associated with a significantly reduced risk of advanced cancer (RR, 0.86; 95% CI, 0.74–0.99). The observed patterns point to pre-diagnostic weight loss of cancer patients and preventive effects of vitamin D3 supplementation from cancer progression as plausible explanations for the body mass index (BMI)—intervention interactions. Further research, including RCTs more comprehensively exploring the potential of adjuvant vitamin D therapy for cancer patients, should be pursued with priority.

Vitamin D Receptor (VDR) Allelic Variants Correlating with Response to Vitamin D3 Supplementation in Breast Cancer Survivors

2021 ◽  
pp. 1-14
Author(s):  
Elham Kazemian ◽  
Sayed Hossein Davoodi ◽  
Mohammad Esmaeil Akbari ◽  
Nariman Moradi ◽  
Safoora Gharibzadeh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Cancer Survivors ◽  
Vitamin D Receptor ◽  
Vitamin D3 ◽  
Breast Cancer Survivors ◽  
Allelic Variants ◽  
Vitamin D3 Supplementation

Vitamin D3 supplementation of beef steers increases longissimus tenderness.

1999 ◽  
Vol 77 (4) ◽  
pp. 874 ◽  
Author(s):  
S S Swanek ◽  
J B Morgan ◽  
F N Owens ◽  
D R Gill ◽  
C A Strasia ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
Beef Steers ◽  
Vitamin D3 Supplementation

scholarly journals Vitamin D and Serum Cytokines in a Randomized Clinical Trial

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Eleanor Yusupov ◽  
Melissa Li-Ng ◽  
Simcha Pollack ◽  
James K. Yeh ◽  
Mageda Mikhail ◽  
...  
Keyword(s):  
Vitamin D ◽  
Placebo Group ◽  
Vitamin D3 ◽  
Intracellular Signaling ◽  
Final Visit ◽  
Active Vitamin ◽  
Gm Csf ◽  
Active Vitamin D ◽  
Significant Difference ◽  
Vitamin D3 Supplementation

Background. The role of vitamin D in the body's ability to fight influenza and URI's may be dependent on regulation of specific cytokines that participate in the host inflammatory response. The aim of this study was to test the hypothesis that vitamin D can influence intracellular signaling to regulate the production of cytokines.Subjects and Methods. This study was a 3-month prospective placebo-controlled trial of vitamin D3 supplementation in ambulatory adults [Li-Ng et al., 2009]. 162 volunteers were randomized to receive either 50 μg/d(2000 IU) of vitamin D3 or matching placebo. 25(OH)D and the levels of 10 different cytokines (IL-2, 4, 5, 6, 8, 10, 13, GM-CSF, IFN-γ, TNF-α) were measured in the serum of participants at baseline and the final visit. There were 6 drop-outs from the active vitamin D group and 8 from the placebo group.Results. In the active vitamin D group, we found a significant median percent decline in levels of GM-CSF (−62.9%,P<.0001), IFN-γ(−38.9%,P<.0001), IL-4 (−50.8%,P=.001), IL-8 (−48.4%,P<.0001), and IL-10 (−70.4%,P<.0001). In the placebo group, there were significant declines for GM-CSF (−53.2%,P=.0007) and IFN-γ(−34.4%,P=.0011). For each cytokine, there was no significant difference in the rate of decline between the two groups. 25(OH)D levels increased in the active vitamin D group from a mean of64.3±25.4 nmol/L to88.5±23.2 nmol/L.Conclusions. The present study did not show that vitamin D3 supplementation changed circulating cytokine levels among healthy adults.

Primary hypoparathyroidism in a cat complicated by suspect iatrogenic calcinosis cutis

2001 ◽  
Vol 37 (4) ◽  
pp. 370-373 ◽  
Author(s):  
JL Ruopp
Keyword(s):  
Adult Male ◽  
Vitamin D3 ◽  
Calcium Gluconate ◽  
Recent Literature ◽  
Calcium Supplementation ◽  
Direct Reaction ◽  
Calcinosis Cutis ◽  
Vitamin D3 Supplementation

An adult male cat presented to the Ontario Veterinary College after having a seizure at the humane society. The cat was diagnosed with primary hypoparathyroidism and was treated with calcium and vitamin D3 supplementation. Calcium supplementation included subcutaneous (SC) administration of diluted calcium gluconate according to protocols described in recent literature. Seven days after SC calcium administration, firm SC masses developed in the intrascapular area where the injections were given and in the dependent axillary area. These areas became raised, formed crusts, necrosed, and left scars. Although not histopathologically confirmed, the author postulates that this was a direct reaction to SC calcium gluconate administration.

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